| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1989: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Research Abstract |
In 1988, we investigated about the quantitative sleep diagram's characteristics, that is titled spindle-delta wave sleep diagram consisting of spindle number variations and delta component investigation values. The former was named spindle pattern abbreviatively, that used to periodically appear across night and its peak values showed approximately same one. The latter had a name of delta pattern, that increased in maximum after the appearance of peak of the spindle pattern and after 30 minutes on the average decreased. These two patterns continued so called REM sleep period. After our study, spindle-enhancing phase was suggested to have a role of the initiation and maintenance for sleeping. On the other hand, spindle-modifying phase of spindle pattern after its peak might be controlled by the state and waking time before the sleep.
In 1989 we analyzed the spindle-delta wave sleep diagram with multiple systematic atrophy, that is, olivo-ponto-cerebellar atrophy (OPCA) and Shy-Drager Syndrome (SDS). Moreover, Myotonic Dystrophy (MD)was also studied in the same way. These neurological diseases generally showed that delta activities were remarkably low and on the spindle structure the averaged amplitude had a tendency of decreases, and also on the delta waves the appearance rate and amplitude decreased. SDS and MD had findings that their averaged frequency of spindles increased comparing with that of normal controls. Also, on the automatic variations heart rate per minute was higher in high activities of delta than in low for subjects with OPCA and SDS. This finding is very paradoxical.
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