| Project/Area Number |
63480359
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Niigata University |
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Principal Investigator |
KANO Ken-ich Niigata Univ. Sch. of Med. Ass. Professor, 医学部, 助教授 (50018686)
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| Co-Investigator(Kenkyū-buntansha) |
TAKAHASHI Hitoshi Niigata Univ. Sch. of Med. Ass. researcher, 医学部, 助手 (60171518)
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| Project Period (FY) |
1988 – 1989
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| Project Status |
Completed (Fiscal Year 1989)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 1989: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1988: ¥2,600,000 (Direct Cost: ¥2,600,000)
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| Keywords | Penis / Erection / Vascular construction / Closed vascular system / Electromagnetic blood flowmeter / Hemodynamics / 血管機構 / イヌ / 勃起神経 / 電気刺戟 / 陰茎動脈および陰茎内動脈の血流の変化 |
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| Research Abstract |
The vascular construction of the dog, monkey and man were investigated mainly by scanning electron microscopic observation of corrosion casts. The corpus cavernosum penis was supplied by the helicine arteries. In the dog and monkey, the vessels were provided with polsters which protruded into the lumen. In man, on the contrary, the helicine arteris had no polsters. The cavernous sinuses strikingly anastomosed each other forming a vascular network. Postcavernous venuies in the corpus cavernosum penis occurred on its dorso-medial surface and ran for a distance beneath the tunica albuginea, and it is apparent that they were effectively compressed between the tunica albuginea and peripheral sinuses during erection. The vascular constructions of dog, monkey and man were basically similar to each other.
Hemodynamic study of the penile erection mechanism was undertaken in the dog using an electromagnetic blood flowmeter. During cavernous nerve stimulation, the blood flows in the penile and bulbourethral. arteries rapidly increased. But the deep arterial flow increased at the beginning of stimulation and decreased to zero in a short time.
These results indicate that the greater part of the increased volume in ihe penile artery flow into the bulbourethral artery and in the corpus cavernosum penis, and blood is isolated from the systemic circulation.
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