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Three-dimensional histological study on the effect of extraoral force to the mandible

Research Project

Project/Area Number 63480453
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 小児・社会系歯学
Research InstitutionNiigata University

Principal Investigator

SASAKURA Hitoshi  Niigata Univ. Sch.of Dent. Associate Professor, 歯学部, 助教授 (70107788)

Co-Investigator(Kenkyū-buntansha) TAKATO Makoto  Niigata Univ. Dental Hospital Assistant, 歯学部附属病院, 助手 (60187979)
高頭 誠  新潟大学, 歯学部附属病院, 助手 (40176144)
Project Period (FY) 1988 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥6,400,000 (Direct Cost: ¥6,400,000)
Fiscal Year 1989: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1988: ¥5,900,000 (Direct Cost: ¥5,900,000)
KeywordsRat / Mandible / Chin cap / Lead-labelling technique / Internal remodeling / Three-dimensional analysis / Ultrasoft x-rays producer / 鉛抽記法 / Chin cap / 顎外力 / 骨改造現象 / 三次元画像解析
Research Abstract

The present study was made to investigate the initial bone remodeling and tissue response of the rat mandible to mandibular retractive force by means of lead-labelling technique, ultrasoft x-rays and three-dimensional analyzing system. Experimental rats were given the chin cap-like appliance and after that, they were sacrificed with the intervals of 5,10,15,20,30 days.
This study gave the following results;
1) At the initial stage after mandibular retraction, cephalometrically lower incisors elongated. After,that, mandibular body was strained and upward force from chin cap applied to anterior portion of the mandible. As a result of this phenomena, it appeared that the mandible rotated counterclockwise and anterior-downward growth of it was controlled.
2) Histologically, the condylar cartilage become gradually thinner and internal remodeling of the ramus was reduced. This indicated that cell proliferation was inhibited at the area of the condylar and ramus.
There was little bone deposition on the lower surface of the mandibular angle, but the bone in the transitional zone actively formed towards the outside.
3) The results from three-dimensional analyzing system was as follows; Slight concave shape was observed at the center of the condylar head and it was inclined deeper according to the wearing duration.
This finding supported the prediction on basis of histological one.

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • Research Products

    (9 results)

All Other

All Publications (9 results)

  • [Publications] 山田一尋,花田晃治,他: "成長に伴うラット下顎骨咬筋深層付着部の移動様式に関する微細構造学的研究" 歯科基礎医学会雑誌. 30. 664-682 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yamada,K.,Hanada,K.et.al: "An Ultrastructural Study of changes in the tendinous Attachment of the Deep Layer of Masseter Muscle to the Rat Mandible during Bite Raising" Anat.Anz.165. 91-104 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 斉藤功,篠倉均,花田晃治,他: "3次元解析システムおよび組織学的手法を利用した顎外力の下顎骨への影響に関する実験的研究" 新潟歯学会雑誌(発表予定). 20. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yamada, K., Hanada, K. et al.: "Ultrastructural study on the migration mechanism of the attachment of the deep layer of masseter muscle to the rat mandible during growth" Japanese Journal of Oral Biology 30; 664-682, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yamada, K., Hanada, K. et al.: "aN Ultrastructural Study of Changes in the Tendinous Attachment of the Deep Layer of Masseter Muscle to the Rat Mandible during Bite Raising" Anat. Anz. Jena, 165; 91-104, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Saito, I., Sasakura, H., Hanada, K. et al.: "An experimental study on the effect of extraoral force to the mandible by use of three-dimensional and histological methods" Niigata Dental Journal 20; 1990. (This paper will be published.).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 山田一尋: "成長に伴うラット下顎骨咬筋深層付着部の移動様式に関する微細構造学的研究" 歯科基礎医学会雑誌. 30. 664-682 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] Yamada,K.: "An Ultrastructural Study of Changes in the tendinous Attachment of the Deep Layer of Masseter Muscle to the Rat Mandible during Bite Raising" Anat.Anz.165. 91-104 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 斉藤功: "3次元解析システムおよび組織学的手法と利用した顎外力の下顎骨への影響に関する実験的研究" 新潟歯学会雑誌. 20. (1990)

    • Related Report
      1989 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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