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Effect of dietary Calcium source to improvement of bone metabolism.

Research Project

Project/Area Number 63480487
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 家政学
Research InstitutionJapan Women's University

Principal Investigator

EZAWA Ikuko  Japan Women's University, Faculty of Home Economics, professor, 家政学部, 教授 (10060641)

Co-Investigator(Kenkyū-buntansha) TAKAGI Chikako  Japan Women's University, Faculty of Home Economics, assistant, 家政学部, 助手 (60120771)
KAWANA Mitsuko  Japan Women's University, Faculty of Home Economics, assistant professor, 家政学部, 助教授 (50060611)
NAKAHAMA Nobuko  Japan Women's University, Faculty of Home Economics, professor, 家政学部, 教授 (90060590)
Project Period (FY) 1988 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥6,900,000 (Direct Cost: ¥6,900,000)
Fiscal Year 1989: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1988: ¥5,400,000 (Direct Cost: ¥5,400,000)
Keywordsosteoporosis model rat / ovariectomy / hard tissue preparation / breaking properties / calcium balance / BMD / MD / whey calcium / 乳清カルシウム / 卵巣摘出ラット / カルシウム出納試験 / 大腿骨MD法 / 脛骨SPA / カルシウム供給源 / 卵巣摘出 / 食物カルシウム源 / 骨破断強度 / 骨軟X線像 / 骨形態計測 / 魚骨粉料理
Research Abstract

Effects of Whey Ca on Bone Metabolism in Ovariectomized Osteoporosis Model Rats
In this study, we investigated the bioavailability of whey in diet as a Ca source, compared to CaCO_3 and CaHPO_4.5-weeks-female rats were ovariecotomized, and then they were fed on the low Ca diet(Ca:0.01%) for 27days. After that, these rats were divided into three groups, whey, CaCO_3 and CaHPO_4. They were estimated Ca balance, microdensitometry and breaking properties of bone. As a result, there were no significant differences in serum Ca levels, food efficiency ratio and body weight gain between those three groups. On the other hand, in whey Ca diet group, the urinary Ca excretion is higher than that of CaCO_3 and CaHPO_4 diet groups. And in whey and CaHPO_4 diet groups, the femur breaking properties and the parameters of micro densitometry, SIGMA GS, SIGMA GS/D, GSmin, GSmax, increased compared to CaCO_3 diet group. And those parameters of whey diet group were a little higher than that of CaHPO_4 diet group (not significant). These results clearly suggest that the whey, as a Ca source, has a beneficial effect on increasing bone strength.

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] 江澤郁子: "卵巣摘出・低Ca食飼育ラットにおける乳情Caの利用効果" 日本栄養・食糧学会誌(予定). 43. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 川名光子: "食物Ca源としての魚骨粉利用について" 調理科学(予定). 23. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Chie Igarashi, Ikuko Ezawa, Etsuro Ogata: "Effects of Whey Calcium on Bone Metabolism in Ovariectomized Osteoporosis Model Rats." Journal of Japanese Society of Nutrition and Food Science, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mitsuko Kawana, Chikako Takagi, Nobuko Nakahama, Keiko Kumeno, Ikuko Ezawa: "Utilization of Fish Bone Powder as the Dietary Calcium Source." Science of Cookery, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 江澤郁子: "卵巣摘出・低Ca食飼育ラットにおける乳清Caの利用効果" 日本栄養・食糧学会誌. 46. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 川名光子: "食物Ca源としての魚骨粉の利用について" 調理科学. 23. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 江澤郁子: Medical Practice. 5. 153-156 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 江澤郁子: 臨床医. 14. 330-332 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 江澤郁子: 自然と人間を結ぶ. 9. 51-55 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 江澤郁子: スズケンPHC. 1. 13-19 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 江澤郁子: The Bone. 3. (1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] 江澤郁子: 日本家政学会誌. (1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] 江澤郁子: "透析患者の骨病変" 前田貞亮、平沢由平、黒川清、鈴木正司, 1-346 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 江澤郁子: "老人と家族の暮らしの相談室part1" 柴田博, 1-289 (1988)

    • Related Report
      1988 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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