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Physio-Pharmaco-Psychological Studies on Learning and Memory in Aged Animals.

Research Project

Project/Area Number 63510044
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Psychology
Research InstitutionUniversity of Tsukuba

Principal Investigator

IWASAKI Tsuneo  University of Tsukuba, Institute of Psychology, Professor, 心理学系, 教授 (70092509)

Project Period (FY) 1988 – 1990
Project Status Completed (Fiscal Year 1990)
Budget Amount *help
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1990: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1989: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1988: ¥1,100,000 (Direct Cost: ¥1,100,000)
Keywordsaged animals / aged rats / learning / memory / discrimination learning / place learning / delayed matching-to-sample learning
Research Abstract

This study was aimed to clarify characteristics of learning and memory in aged animals. Aged (14-27months old) rats were compared with youn g(2-3 months old) rats on their learning and memory performances in the following tasks.
(1) Position (right vs. lef) discrimination learning in Grice box.
(2) Brightness (black vs. white) discrimination learning in Grice box.
(3) Place learning in 8-arm radial-arm maze.
(4) Delayed matching-to-sample learning and memory test in trough T-maze.
(5) Delayed matching-to-sample learning and memory test in trough Y-maze.
(6) Delayed matching-to-sample learning and memory test in elevated Y-maze.
The results indicated that the aged rats showed deficits in learning and memory Performances, especially on the tasks in which sufficient discrimination cues were not available. It should be noted, however, that individual differences were much greater in aged than in young animals.

Report

(4 results)
  • 1990 Annual Research Report   Final Research Report Summary
  • 1989 Annual Research Report
  • 1988 Annual Research Report
  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] 岩崎 庸男: "老齢ラットの明暗弁別と位置弁別学習" 筑波大学心理学研究. 11. 43-47 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 古川 聡: "老齢ラットにおける放射状迷路学習の障害" 心理学研究. 60. 192-195 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 古川 聡: "ラットの遅延見本合わせおよび非見本合わせ反応に及ぼすscopolamineの効果" 薬物・精神・行動. 9. 273-280 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 古川 聡: "老齢ラットの遅延見本合わせ反応の障害" 心理学研究.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Iwasaki, T.: "Brightness and position discrimination learning in senescent rats." Tsukuba Psychological Research. 11. 43-47 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Furukawa, S.: "Deficits in radial-arm maze learning in aged rats." Japanese Journal of Psychology. 60. 192-195 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Furukawa, S.: "Effects of scopolamine on delayed matching and non-matching to sample responses in T-maze in rats." Japanese Journal of Psychopharmacology. 9. 273-280 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Furukawa, S.: "Deficits in delayed matching to sample responses in Y-maze in aged rats." Japanese Journal of Psychology.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 岩崎 庸男: "老齢ラットの明暗弁別と位置弁別学習" 筑波大学心理学研究. 11. 43-47 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 古川 聡: "老齢ラットにおける放射状迷路学習の障害" 心理学研究. 60. 192-195 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 古川 聡: "ラットの遅延見本合わせおよび非見本合わせ反応に及ぼすscopolamineの効果" 薬物・精神・行動. 9. 273-280 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 古川 聡: "老齢ラットの遅延見本合わせ反応の障害" 心理学研究.

    • Related Report
      1990 Annual Research Report
  • [Publications] 岩崎庸男: "老齢ラットの明暗弁別と位置弁別学習" 筑波大学心理学研究. 11. 43-47 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 古川聡: "老齢ラットにおける放射状迷路学習の障害" 心理学研究. 60. 192-195 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 古川聡: "ラットの遅延見本合わせおよび非見合わせ反応に及ぼすscopolamineの効果" 薬物・精神・行動. 9. 273-280 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 岩崎庸男: 筑波大学心理学研究. 11. 43-47 (1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] 古川聡: 心理学研究. 60. (1989)

    • Related Report
      1988 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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