| Project/Area Number |
63570505
|
|---|
| Research Category |
Grant-in-Aid for General Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | OSAKA UNIVERSITY MEDICAL SCHOOL |
|---|
Principal Investigator |
MORIMOTO Sigeto Osaka University Medical School, Department of Geriatic Medicine, Instructor, 医学部, 助手 (20150336)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HIRONAKA Takashi Osaka University Medical School, Department of Geriatic Medicine, Fellow, 医学部附属病院, 医員
大西 利夫 大阪大学, 医学部(老年病医学), 助教授 (50107041)
|
|---|
| Project Period (FY) |
1988 – 1989
|
| Project Status |
Completed (Fiscal Year 1989)
|
| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1989: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1988: ¥700,000 (Direct Cost: ¥700,000)
|
|---|
| Keywords | Senile dementia / Senile dementia of Alzheimer's type / Senile dementia of vascular type / Calcium / Parathyroid hormone / Calcitonin / 1,25-dihydroxyvitamin D / 1,25ージヒドロキシビタミンD / アルツハイマー型老年期痴呆 / 脳血管性痴呆 |
|---|
| Research Abstract |
Calcium-related factors were compared in 60 elderly female subjects, who were classified into three groups as nondementia group (n=18), groups of senile dementia of Alzheimer type (SDAT, n=22) and of vascular type (VTD, n=20), The group of SDAT showed significant decrease in scrum calcium, and increases in serum parathyroid hormone and urinary Ca, and tendency of decrease in serum 1,25-dihydroxyvitamin D, compared to those of the nondementia group. However, the group of VTD, without showing these features, showed a tendency towards decreased scrum calcitonin. These results suggest that Ca and Ca-regulating hormones may play several important and different roles in senile dementia.
|
