• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Bone Disorder in Gastrectomized Patients and Studies on its Prophylaxis and Therapy

Research Project

Project/Area Number 63570634
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionTottori University

Principal Investigator

NISHIMURA Okitsugu  Tottori University, Faculty of Medicine, Associate Professor, 医学部, 助教授 (00032227)

Co-Investigator(Kenkyū-buntansha) HISAKI Toshiko  Tottori University Hospital, Research Associate, 医学部附属病院, 助手 (60218708)
小立 寿成  鳥取大学, 医学部附属病院, 助手 (80185610)
Project Period (FY) 1988 – 1990
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1990: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1989: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1988: ¥800,000 (Direct Cost: ¥800,000)
Keywordsgastrectomy / bone disorder / bone mass / vitamin D / 胃切除後骨障害 / 骨萎縮 / 骨量変動
Research Abstract

To study the incidence of post-gastrectomy bone disorders, bone mass was measured in long-term survivors more than three years after gastrectomy. A prospective study on the onset of bone disorder was made in new patients, their bone mass was evaluated and followed before and after gastrectomy. Another study was performed on the significance of prophylactic and therapeutic use of vitamin D for the bone disorder.
1)A high incidence of bone loss, approximately 50 percent, was pronounced in long-term survivors after gastrectomy. The incidence was pronounced, especially in totally gastrectomized patients and in more longer-term survived patients.
2)Results of the prospective study on the beginning of bone atrophy were as follows.
No change was found within one year after gastrectomy, however, the bone loss was observed morethan 2 years after gastrectomy. The incidence of the bone atrophy was 56% in male and 36% in female respectively. This finding was thought to be more earliver stage than in the previous understanding. But, factors of background of these patients with bone atrophy could not be clarified.
3)No significant results were obtained in administration of vitamin D drug for prophylactic and therapeutic use on the bone atrophy.
Another study on the bone disorder after gastrectomy should be made and a follow-up our patients should be continued in more longer period after surger.

Report

(4 results)
  • 1991 Final Research Report Summary
  • 1990 Annual Research Report
  • 1989 Annual Research Report
  • 1988 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] 西村 興亜,古賀 成昌: "消化器外科セミナ- 35 胃切除後の病態と治療ー最近の進歩,骨代謝障害(分担)" へるす出版, 166 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 古賀 成昌,西村 興亜: "消化器疾患最近の治療ー胃切除後症候群(分担)" 南江堂, 482 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Okitsugu Nishimura, Shigemasa Koga: "Metabolic bone disorder after gastrectomy." Seminar of Gastroenterological Diseases. 35. 64-79 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shigemasa Koga, Okitsugu Nishimura: "Postgastrectomy syndrome." Todays Therapy of Gastroenterological Diseases. Nankodo, Tokyo. 155-167 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 西村 興亜: "胃切除後の骨変化について" 和歌山県医師会 外科・整形外科雑誌. 10. 13-23 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 西村 興亜,古賀 成昌: "消化器病セミナ-35・胃切除後の病態と治療ー最近の進歩、骨代謝障害(分抱)" へるす出版, 166 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 古賀 成昌,西村 興亜: "消化器疾患最近の治療ー胃切除症候群(分抱)" 南江堂, 482 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 西村興亜: "胃切除と骨粗鬆症" 骨と関節. 2. 18-21 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 西村興亜: "胃切除後の骨変化について" 和歌山県医師会外科整形外科部会雑誌. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 武藤輝一編(分担)西村興亜: "消化器病セミナ-35.胃切除後の病態と治療-最近の進歩(分担)骨代謝障害(pp,63-89)" へるす出版,東京, 166 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 岡博ほか編(分担)古賀成昌: "消化器疾患最近の治療'89-'90(分担)胃切除後症候群(pp,155-164)" 南江堂,東京, 482 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 西村興亜: 日本外科学会雑誌. 88. 1684-1694 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 貝原信明: 臨床と研究. 65. 2452-2458 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 西村興亜: 骨と関節. 2. 18-21 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 西村興亜: 和歌山県医師会外科整形外科部会雑誌. (1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] 古賀成昌: "消火器疾患:胃切除後遺症群最近の治療" 南江堂, (1989)

    • Related Report
      1988 Annual Research Report

URL: 

Published: 1988-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi