| Project/Area Number |
63570744
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | SHINSHU UNIVERSITY SCHOOL OF MEDICINE |
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Principal Investigator |
FUKUI Junnosuke SHINSHU UNIVERSITY SCHOOL OF MEDICINE, UROLOGY, ASSOCIATE PROFESSOR, 医学部・泌尿器科, 助教授 (50115367)
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| Co-Investigator(Kenkyū-buntansha) |
OKADA Noboru 信州大学, 医学部・泌尿器科, 助手 (80177055)
ISHIZUKA Osamu 信州大学, 医学部・泌尿器科, 助手 (20184541)
YAMASHITA Toshio 信州大学, 医学部・泌尿器科, 助手 (10200685)
吉村 明 信州大学, 医学部・泌尿器科, 助手 (10201047)
中本 富夫 信州大学, 医学部・泌尿器科, 助手 (10135139)
小川 秋実 信州大学, 医学部・泌尿器科, 教授 (10009954)
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| Project Period (FY) |
1988 – 1989
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| Project Status |
Completed (Fiscal Year 1989)
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| Budget Amount *help |
¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 1989: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1988: ¥700,000 (Direct Cost: ¥700,000)
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| Keywords | ELECTRICAL STIMULATION / NEUROPATHIC BLADDER / SPINAL SHOCK / NON-CATHETERIZED BLADDER DRAINAGE / SACRAL NERVE PLEXUS / 脊髄損傷 / 排尿 / 仙骨神経刺激 / 電気刺激法 / 針電極 |
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| Research Abstract |
An electrode make up of 19 helical stainless-steel wires of 25mu m in diameter and coated by Teflon was used for electrical stimulation of the anterior sacral roots to induce a micturition.
In two patients with acute spinal cord injury (injury of C_<6-7> or Th_<5-6>) and one patient with subacute spinal cord injury (injury of Th1_<2->-L_1), the electrode was percutaneously inserted into the sacral plexus through the 2nd, 3rd and 4th sacral canals. Electrical stimulation failed to elicit voiding in all patients, although the vesicle pressure rose up to 20 to 30 cm of water. It seeded difficult to place the electrode on the sacral nerve plexds percutaneously.
In 5 dogs the electrode was placed anterior to the 1 st and 2nd sacral nerves after a laminecromy. Stimulation of the sacral nerves resulted in an incomplete emptying of their bladders. Because of a simultaneous contraction of the urethral sphincter during electrical stimulation, the average rate of voiding efficiency. was 20%.
The results indicate that relaxation of the urethral sphincter is necessary to obtain an efficient voiding by electrical stimulation, and this requires further study.
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