| Project/Area Number |
63580139
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
物質生物化学
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| Research Institution | National Center of Neurology and Psychiatry (NCNP) |
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Principal Investigator |
MOMOI Takashi NCNP, Chief researcher, 神経研究所5部, 室長 (40143507)
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| Co-Investigator(Kenkyū-buntansha) |
佐藤 淳子 国立精神神経センター, 神経研究所・第5部, 研究者
北本 年弘 国立精神, 神経センター神経研究所・第5部, 研究所
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| Project Period (FY) |
1988 – 1989
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| Project Status |
Completed (Fiscal Year 1989)
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| Budget Amount *help |
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1989: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1988: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | Retinoic acid / Cellular retinoic acid / binding protein / Retinoic acid receptor / neurogenesis / neural tube / ガングリオシド / 形態形成因子 / 細胞内レチノイン酸結合タンパク / CRABP / モルフォージュン |
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| Research Abstract |
We previously demonstrated the presence of cellular retinoic acid binding protein II, chick-CRABP II, in chick embryos. In the present study, we investigated the distribution of chick-CRABP II in 14-day chick embryos by means of immunoblot analysis. Chick-CRABP II was expressed in skin, muscle, bone with tendon of the embryos, but not expressed in the nervous system. In adult chick tissues, chick CRABP II was not detected on immunoblotting; Chick-CRABP II in adults amounts to less than long/mg soluble embryonic protein involved in the development of specific tissues, such as bone, muscle and skin.
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