| Project/Area Number |
63870055
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| Research Category |
Grant-in-Aid for Developmental Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Nagoya University school of Medicine |
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Principal Investigator |
NEGORO M. Instructor, Department of Neurosurg., 医学部, 助手 (90115618)
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| Co-Investigator(Kenkyū-buntansha) |
浅井 潔 ダウコーニング社, メディカル技術課, 課長
ISHIGUCHI T. Instructor, Dept. of Radiology, 医学部, 講師 (70115525)
宮地 茂 名古屋大学, 医学部, 医員
ASAI K. Div. of Medical Product, Dow Corning Comp
MIYACHI S. Research Associate, Dept. of Neurosurg.
寺島 圭一 名古屋大学, 医学部, 医員
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| Project Period (FY) |
1988 – 1990
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| Project Status |
Completed (Fiscal Year 1990)
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| Budget Amount *help |
¥5,700,000 (Direct Cost: ¥5,700,000)
Fiscal Year 1990: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1989: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1988: ¥4,300,000 (Direct Cost: ¥4,300,000)
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| Keywords | Experimental aneurysm / Latex balloon / Silicone balloon / Thrombus formation / Endovascular treatment / 血栓形成 / 血管内治療 / Hema / バルーンカテーテル / 血流動態 / 形状記憶合金コイル |
|---|
| Research Abstract |
Recent advance of endovascular occlusion technique has brought a significant change in the treatment of cerebral aneurysm. However, there are still unsolved problem in such therapy.
To find out the definitive method for endovascular treatment, experimental aneurysms were produced in the carotid artery of dogs by venous patch method. Using detachable balloons or coils, intraluminal occlusion of the aneurysm was made. These procedures were performed under the observation by the vascular endoscopy in selected cases. Those treated aneurysms were studied angiographically and histologically. Coils (esp. nitonol coil) as well as balloon were able to occlude the aneurysmal cavity maintaining the parent arte flow.
The occlusion rate of latex balloon was superior to silicone balloon. We will proceed to make such detachable balloon systems for clinical application.
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