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Development of a new type of student's manual for laboratory work in biology.

Research Project

Project/Area Number 63880036
Research Category

Grant-in-Aid for Developmental Scientific Research

Allocation TypeSingle-year Grants
Research Field 科学教育(含教育工学)
Research InstitutionUniversity of Tokyo

Principal Investigator

TAKAHASHI Keiichi  Zoological Institute, Faculty of Science, University of Tokyo. Professor., 理学部, 教授 (40011481)

Co-Investigator(Kenkyū-buntansha) ISHII Naokata  Zoological Institute, Faculty of Science, University of Tokyo. Instructor., 理学部, 助手 (20151326)
SHINGYOJI Chikako  Zoological Institute, Faculty of Science, University of Tokyo. Instructor., 理学部, 助手 (80125997)
MURAKAMI Akira  Zoological Institute, Faculty of Science, University of Tokyo. Assistant Profess, 理学部, 助教授 (10021924)
Project Period (FY) 1988 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥5,300,000 (Direct Cost: ¥5,300,000)
Fiscal Year 1989: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1988: ¥3,200,000 (Direct Cost: ¥3,200,000)
KeywordsLaboratory manuals / Biological education / Laboratory in biology / パ-ソナル・コンピュ-タ / パ-ソナルコンピュ-タ / 大学における生物実習 / 高等学校における生物実習 / 生物実験マニュアル作成支援ソフトウェア / パーソナルコンピューター / 動物生理学実習
Research Abstract

one of the major difficulties in teaching biological sciences at high schools and universities is in the laboratory as the practicability of a subject is severely limited by the availability of biological materials and the equipments, and by the skill and experience of teachers or instructors. To remove some of the difficulties; an attempt was made to develop a software for personal computers by which teachers can edit their own version of student's manuals for the laboratory suitable for their individual needs and circumstances The software we have developed consists of a simple editor, text files divided into small blocks, and programs for statistical analyses including linear and non-linear regressions. Teachers can choose, rearrange and even rewrite the text to construct their own instruction manuals at the level of the operating system (MS-DOS, Japanese version), though much finer reorganization of the text can be made by the aid of word processors such as the WordStar. Using this software, we produced instruction manuals for the following subjects and tested them in the physiology course at the Zoological Institute, University of Tokyo: 1. 'The basis of neurophysiology'; 2. 'Physiology of muscle contraction; 3. 'Cell motilityl. The application was successful in that the time required for the preparation of instruction was significantly shortened and the instruction became much more comprehensive to the students. However, some problems such as the management of figures and illustrations were left to be solved. In addition to these problems, application of the software to the practices in high schools and junior high schools should also be studied further.

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • Research Products

    (43 results)

All Other

All Publications (43 results)

  • [Publications] Yoshimura,K.and K.Takahashi: "Partial extraction of inner dynein arms from an outer arm-less mutant of Chlamydomonas reinhadtii" Cell Struct.Funct.14. 741-749 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Katada,J.,C.Shingyoji and K.Takahashi: "Effects of detergents used to demembranate the sea-urchin spermatozoa on the reactivated flagellar movement,with special reference to the rotatability of the plane of flagellar beat" Cell Struct.Funct.14. 751-758 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Abe,O.,T.Yamada,K.Takahashi and H.Sugi: "Initiation of active force development in a molluscan smooth muscle by laser Photolysis of caged ATP." Proc.Japan Academy Ser.B. 65. 165-168 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yamada,A.,N.Ishii,T.Shimmen and K.Takahashi: "Mg-ATP activity and motility of native thick filaments isolated from the anterior byssus retractor muscle of Mytilus edulis." J.Muscle Res.Cell Motility. 10. 124-134 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ishii,N.,F.Mitsumori,K.Takahashi,A.W.M.Simpson and C.C.Ashley: "Intracellular metabolite and free calcium concentrations during the'catch'contracation and relaxation in a molluscan smooth muscle." Muscle Energetics(ed.R.Paul),Alan R.Liss,NY in Press.(1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Eshel,D.,C.Shingyoji,K.Yoshimura,B.H.Gibbons,I.R.Gibbons and K.Takahashi: "Transient behavior of sea urchin sperm flagella following an abrupt change in beat frequency." J.exp.Biol.,in Press.(1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Shingyoji,C.,I.R.Gibbons,A.Murakami and K.Takahashi: "Effects of imposed head vibration on the stability and waveform of flagellar beating in sea urchin spematozoa." J.exp.Biol.,submitted.(1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ishii,N.,A.W.M.Simpson and C.C.Ashley: "Free-calcium at rest durihg“catch"in single smooth muscle cells" Science. 243. 1367-1368 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Murakami,A.: "The control of cilia in metazoa:Ciliary functions and Ca-dependent responses" Comp.Biochem.Physiol.94A. 375-382 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 石井直方: "'Catch'とTatch'-平滑筋の張力維持機構をめぐって、" 実験医学. vol.8(NO.1). 58-61 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Murakami, A. and K. Takahashi: "Gravitaxis of Paramecium." Biological Sciences in Space, 2: 228-237.1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Oiwa, K. and K. Takahashi: "Force-velocity relation of microtubule sliding in demembranated sperm flagella of the sea urchin." Cell Struct. Funct., 13: 193-205.1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Oiwa, K. and K. Takahashi: "The mechanical power developed by dynein arms in sliding microtubules of flagella." In Yamada Conference XI: Energy Transduction in ATPases (eds. Y. Mukohata, M. F. Morales and S. Fleischer), Yamada Science Foundation, Osaka. pp. 210-211, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Shingyoji, C.: "Control of microtubule sliding in flagella." Proc. 14th Taniguchi Int. Symp. (Division of Biophysics) on Dynamics of Microtubules (ed. H. Hotani), Taniguchi Foundation. pp. 89-103, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yamada, A., N. Ishii, T. Shimmen and K. Takahashi: "Mg-ATP activity and motility of native thick filaments isolated from the anterior byssus retractor muscle of Mytilus edulis." J. Muscle Res. Cell Motility, 10: 124-134.1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Abe, O., T. Yamada, K. Takahashi and H. Sugi: "Initiation of active force development in a molluscan smooth muscle by laser photolysis of caged ATP." Proc. Japan Academy Ser. B, 65: 165-168.1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Katada, J., C. Shingyoji and K. Takahashi: "Effects of detergents used to demembranate the sea-urchin spermatozoa on the reactivated flagellar movement, with special reference to the rotatability of the plane of flagellar beat." Cell Struct. Funct., 14: 751-758.1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yoshimura, K. and K. Takahashi: "Partial extraction of inner dynein arms from an outer arm-less mutant of Chlamydomonas reinhadtii." Cell Struct. Funct., 14: 741-749.1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Eshel, D., C. Shingyoji, K. Yoshimura, B. H. Gibbons, I. R. Gibbons and K. Takahashi: "Transient behavior of sea urchin sperm flagella following an abrupt change in beat frequency." J. exp. Biol., 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Shingyoji, C., I. R. Gibbons, A. Murakami and K. Takahashi: "Effects of imposed head vibration on the stability and waveform of flagellar beating in sea urchin spermatozoa." J. exp. Biol., 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Murakami, A.: "The control of cilia in metazoa: Ciliary functions and Ca-dependent responses." Comp. Biochem. Physiol., 94A: 375-382.1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ishii, N., A. W. M. Simpson and C. C. Ashley: "Carbachol and KCl-induced changes in intracellular free calcium concentration in isolated, fura-2 loaded smooth-muscle cells om the anterior byssus retractor muscle of Mytilus edulis." Biochem Biophys. Res. Commun., 153: 683-689.1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ishii, N., A. W. M. Simpson and C. C. Ashley: "Free-calcium at rest during "catch" in single smooth muscle cells." Science, 243: 1367-1368.1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ishii, N., F. Mitsumori, K. Takahashi, A. W. M. Simpson and C. C. Ashley: "Intracellular metabolite and free calcium concentrations during the 'catch' contracation and relaxation in molluscan smooth muscle." Muscle Energetics (ed. R. Paul), Alan R. Liss, NY 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yoshimura,K.and K.Takahashi: "Partial extraction of inner dynein arms from an outer arm-less mutant of Chlamydomonas reinhadtii" Cell Struct.Funct. 14. 741-749 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Katada,J.,C.Shingyoji and K.Takahashi: "Effects of detergents used to demembranate the sea-urchin spermatozoa on the reactivated flagellar movement,with special reference to the rotatability of the plane of flagellar beat" Cell Struct.Funct. 14. 751-758 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Abe,O.,T.Yamada,K.Takahashi and H.Sugi: "Initiation of active force development in a molluscan smooth muscle by laser photolysis of caged ATP." Proc. Japan Acaddemy Ser.B. 65. 165-168 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Yamada,A.,N.Ishii,T.Shimmen and K.Takahashi: "Mg-ATP activity and motility of native thick filaments isolated from the anterior byssus retractor muscle of Mytilus edulis." J.Muscle Res.Cell Motility. 10. 124-134 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Ishii,N.,F.Mitsumori,K.Takahashi,A.W.M.Simpson and C.C.Ashley: "Intracellular and free calcium concentrations during the‘catch'contracation and relaxation in a molluscan smooth muscle" Muscle Energetics(ed.R.Paul),Alan R.Liss,NY in press. (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Eshel,D.,C.Shigyoji,K.Yoshimura,B.H.Gibbons,I.R.Gibbons and K.Takahashi: "Transient behavior of sea urchin sperm flagella following an abrupt change in beat frequency" J.exp.Biol.,in press.(1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] Shingyoji,C.,I.R.Gibbons,A.Murakami and K.Takahashi: "Effects of imposed head vibration on the stability and wavwform of flagellar beating in sea urchin spematozoa" J.exp.Biol.,submitted. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] Ishii,N.A.W.M.Simpson and C.C.Ashley: "Free-calcium at rest during“catch"in single smooth muscle cells." Science. 243. 1367-1368 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Murakami,A.: "The control of cilia in metazoa:Ciliary functions and Ca-dependent responses." Comp.Biochem.Physiol.94A. 375-382 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 石井直方: "‘Catch'と‘Iatch'-平滑筋の張力維持機構をめぐって" 実験医学. vol.8(No.1). 58-61 (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 村上彰,高橋景一: 宇宙生物科学. 2. 228-237 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Oiwa,K.;k.Takahashi: Cell Struct.Funct.13. 193-205 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Oiwa,K.;K.Takahashi: Yamada conference XI:Energy Transduction in ATPases(eds.Y.Mukohata,M.F.Morales and S.Fleischer)Yamada Science Foundation,Osaka. 210-211 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 真行寺千佳子,高橋景一: 生体の科学. 39. 92-97 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 真行寺千佳子,高橋景一: 生体の科学. 39. 491-492 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Ishii,N.;A.W.M.Simpson;C.C.Ashley: Pflugers Arch.

    • Related Report
      1988 Annual Research Report
  • [Publications] Ishii,N.;A.W.M.Simpson;C.C.Ashley: Science.

    • Related Report
      1988 Annual Research Report
  • [Publications] Ishii,N.;F.Mitsumori;K.Takahashi;A.W.M.Simpson;C.C.Ashley: Muscle Energetics(ed.R.Paul),Alan R.Liss,NY.

    • Related Report
      1988 Annual Research Report
  • [Publications] Yamada,A.;N.Ishii;T.Shimmen;K.Takahashi: J.Muscle Res.Cell Motility.

    • Related Report
      1988 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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