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筋肉協調運動の脳内身体表現学理と脳波を用いた可視化によるリハビリ支援技術の開発

Publicly Offered Research

Project AreaUnderstanding brain plasticity on body representations to promote their adaptive functions
Project/Area Number 17H05903
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionTokyo Institute of Technology

Principal Investigator

吉村 奈津江  東京工業大学, 科学技術創成研究院, 准教授 (00581315)

Project Period (FY) 2017-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
Fiscal Year 2018: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Keywords脳波 / 運動デコーディング / シナジー解析 / 筋シナジー / 運動 / 脳・神経 / 情報工学 / 機械学習
Outline of Annual Research Achievements

本研究では、非侵襲的脳活動計測手法を用いて手や足の運動に関する脳内情報処理過程と筋肉の協調活動(筋シナジー)を可視化することを目的としている。この可視化技術を確立することで、短長期的な運動学習による脳内情報処理や筋シナジー体系の変容を直感的に捉えることができ、効果的なリハビリ介入にも応用可能と考えている。
昨年度までに、運動の種類の識別で高い精度が得られれば運動に関連する脳の領域を調べることができること、そして脳波の信号源電流信号を用いることで運動の違いの識別精度を向上させることができること、を示したことの発展として、今年度はその実用応用に向けて、信号源推定における電極数の検討と、識別器の精度向上に役立つ手法の提案を行った。
電極数については8個に削減すると精度が有意に低下するが、同じ8個でも脳全体を覆うように配置することで有意にはならないことを確認し、国際雑誌IJERASにて発表した。また、識別精度を向上させる手法については、以下の2つを提案した。1つめは、ユーザーが意図した動きと異なる動きを見たり体験した場合に生じる運動予想誤差に関する脳活動を脳波から検出することで、現在最も汎用性の高い事象関連脱同期現象を用いた運動意思の抽出方法と比較して短時間で且つユーザーによる精度のばらつきも小さい識別方法が提供できることを示し、国際雑誌Science Advancesにて発表した。次に2つめは、2つの現象の識別においてこれまで提案されていた2つの波形の位相の同期度合いを指標とするPhase Locking Valueを用いた手法に加えて、2つの波形の位相同期度合いだけでなく振幅の違いを加えることで、識別精度が底上げされることを示し、国際雑誌Chaosにて発表した。

Research Progress Status

平成30年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

平成30年度が最終年度であるため、記入しない。

Report

(2 results)
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (25 results)

All 2019 2018 2017 Other

All Int'l Joint Research (8 results) Journal Article (7 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 7 results,  Open Access: 7 results) Presentation (8 results) (of which Int'l Joint Research: 4 results) Remarks (2 results)

  • [Int'l Joint Research] Polish Academy of Science(ポーランド)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Trento/University of Catania(イタリア)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Tuebingen(ドイツ)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of California San Diego(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of California San Diego(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University of Trento(イタリア)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Polish Academy of Sciences(ポーランド)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University of Tuebingen(ドイツ)

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Warped phase coherence: an empirical synchronization measure combining phase and amplitude information2019

    • Author(s)
      Minati L., Yoshimura N., Frasca M., Drozdz S., and Koike Y.
    • Journal Title

      Chaos

      Volume: 29 Issue: 2 Pages: 1-21

    • DOI

      10.1063/1.5082749

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Classification of Movement Intention Using Independent Components of Premovement EEG2019

    • Author(s)
      Kim H., Yoshimura N., Koike Y.
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 13 Pages: 1-10

    • DOI

      10.3389/fnhum.2019.00063

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Utilizing sensory prediction errors for movement intention decoding: a new methodology2018

    • Author(s)
      Gowrishankar Ganesh, Keigo Nakamura, Supat Saetia, Alejandra Mejia Tobar, Eiichi Yoshida, Hideyuki Ando, Natsue Yoshimura, Yasuharu Koike
    • Journal Title

      Science Advances

      Volume: 4 Issue: 5 Pages: 1-8

    • DOI

      10.1126/sciadv.aaq0183

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of the EEG sensor number on the current-source decoder performance based on a variational Bayesian method (VBMEG)2018

    • Author(s)
      Alejandra Mejia Tobar, Yousuke Ogata, Kahori Kita, Tatsuhiro Nakamura, Hiroyuki Kambara, Takashi Hanakawa, Yasuharu Koike, and Natsue Yoshimura,
    • Journal Title

      International Journal of Engineering Research and Allied Sciences (IJERAS)

      Volume: 3 Pages: 25-29

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Decoding of Ankle Flexion and Extension from Cortical Current Sources Estimated from Non-invasive Brain Activity Recording Methods2018

    • Author(s)
      Mejia Tobar Alejandra、Hyoudou Rikiya、Kita Kahori、Nakamura Tatsuhiro、Kambara Hiroyuki、Ogata Yousuke、Hanakawa Takashi、Koike Yasuharu、Yoshimura Natsue
    • Journal Title

      Frontiers in Neuroscience

      Volume: 11 Pages: 1-12

    • DOI

      10.3389/fnins.2017.00733

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Versatile Locomotion Control of a Hexapod Robot Using a Hierarchical Network of Nonlinear Oscillator Circuits2018

    • Author(s)
      Minati Ludovico、Frasca Mattia、Yoshimura Natsue、Koike Yasuharu
    • Journal Title

      IEEE Access

      Volume: 6 Pages: 8042-8065

    • DOI

      10.1109/access.2018.2799145

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Decoding finger movement in humans using synergy of EEG cortical current signals2017

    • Author(s)
      Yoshimura Natsue、Tsuda Hayato、Kawase Toshihiro、Kambara Hiroyuki、Koike Yasuharu
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-017-09770-5

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Yes/No Classification of Completely Locked-In Syndrome (CLIS) Patients Using EEG Cortical Current Based on Standard Brain Model2018

    • Author(s)
      Umetsu K., Chaudhary U., Malekshahi A., Rana A., Koike Y., Birbaumer N., Yoshimura N.
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Hand movement reconstruction system using FES and EMG for hemiplegia patients.2018

    • Author(s)
      Koki Okada, Toshiki Matsunaga, Yoichi Shimada, Natsue Yoshimura, Yasuharu Koike
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of Vibrotactile Stimulations using Condition Based Time Coding for Haptic Information Feedback.2018

    • Author(s)
      Tomoya Hayashi, Hiroyuki Kambara, Natsue Yoshimura, Yasuharu Koike
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] EEG cortical current source estimation and synergy analysis2018

    • Author(s)
      Natsue Yoshimura
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 運動座標系の脳内表象解析2018

    • Author(s)
      吉村奈津江
    • Organizer
      MRI講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Synergy analysis for motor decoding2017

    • Author(s)
      Yoshimura Natsue, Kawase Toshihiro, Koike Yasuharu
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Classification of ankle flexion and extension tasks using non-invasive brain activity recording methods2017

    • Author(s)
      Mejia Tobar Alejandra, Hyoudou RIkiya, Kita Kahori, Nakamura Tatsuhiro, Kambara Hiroyuki, Hanakawa Takashi, Koike Yasuharu, Yoshimura Natsue
    • Organizer
      Graz BCI Conference 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Brain activity synergy analysis for motion decoding2017

    • Author(s)
      Yoshimura Natsue, Tsuda Hyato, Kawase Toshihiro, Kambara Hiroyuki, Koike Yasuharu
    • Organizer
      Yamada Symposium 2017
    • Related Report
      2017 Annual Research Report
  • [Remarks] 東京工業大学プレスリリース

    • URL

      https://www.titech.ac.jp/news/2019/044076.html

    • Related Report
      2018 Annual Research Report
  • [Remarks] 東京工業大学プレスリリース

    • URL

      https://www.titech.ac.jp/news/2018/041609.html

    • Related Report
      2018 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2022-02-28  

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