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脳卒中患者の運動主体感を高めるハイブリッド型ニューロリハビリテーションの効果検証

Publicly Offered Research

Project AreaUnderstanding brain plasticity on body representations to promote their adaptive functions
Project/Area Number 17H05915
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionKio University

Principal Investigator

森岡 周  畿央大学, 健康科学部, 教授 (20388903)

Project Period (FY) 2017-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2018: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywords脳卒中 / 身体性 / 多感覚統合 / 運動主体感 / 失行症 / 運動障害 / 身体意識 / ニューロリハビリテーション / 片麻痺 / 機能回復
Outline of Annual Research Achievements

本年度に関しては,次の3つの研究を遂行した.1) 同一被験者に遅延検出タスクおよびAgency Attribution taskを実施して,運動-感覚間の不一致に気づく時間窓と運動主体感が損なわれる時間窓の相違性と類似性を検証することを目的とし実験を行なった.2) 脳卒中後の失行患者を対象にして,その者の多感覚統合機能を定量的に捉え,病巣との関連性を検討することを目的に調査を行なった.3) 身体に感覚閾値未満のランダムな周波数ノイズを加えることにより,感覚入力や運動機能が改善させる現象である確率共鳴(Stochastic Reasonance:SR)の提供が,身体性変容に関わる感覚-運動統合機能に影響を与えるか実験を行なった.なお運動主体感が運動-感覚の比較照合プロセスに準じているのならば,遅延を検出する時間と運動主体感が損なわれる時間との間には,密接な関係があると仮説立てて実験を行なった.その結果,運動主体感の変容には運動-感覚の比較照合以外の要因も考えられることが明らかになった.また,脳卒中後の失行症においては,ナラティブな運動主体感は変容していないものの,運動‐感覚フィードバックの遅延を検出する時間窓が有意に遅延していることも判明した.その遅延検出閾値の異常と関係している損傷部位をVoxel-based lesion-symptom mappingによって分析した結果,左前頭-頭頂ネットワーク上の左下前頭回および左下頭頂小葉といった病巣が関係していることが明らかになった.加えて,このような遅延検出能力を向上させるリハビリテーション手段も検討し,体性感覚閾値以下の振動刺激が運動‐感覚フィードバックの遅延を検出する能力を向上させることが明らかになった.これらの一連の研究から,身体性変容を捉える定量的評価方法の確立およびそのリハビリテーション手段の考案に貢献した.

Research Progress Status

平成30年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

平成30年度が最終年度であるため、記入しない。

Report

(2 results)
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (29 results)

All 2018 2017 Other

All Journal Article (8 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 8 results,  Open Access: 6 results) Presentation (18 results) (of which Int'l Joint Research: 9 results,  Invited: 4 results) Book (1 results) Remarks (2 results)

  • [Journal Article] Sensorimotor incongruence alters limb perception and movement2018

    • Author(s)
      Osumi M, Nobusako S, Zama T, Taniguchi M, Shimada S, Morioka S.
    • Journal Title

      Human Movement Science

      Volume: 57 Pages: 251-157

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Distortion of Visuo-Motor Temporal Integration in Apraxia: Evidence From Delayed Visual Feedback Detection Tasks and Voxel-Based Lesion-Symptom Mapping2018

    • Author(s)
      Nobusako S, Ishibashi R, Takamura Y, Oda E, Tanigashira Y, Kouno M, Tominaga T, Ishibashi Y, Okuno H, Nobusako K, Zama T, Osumi M, Shimada S, Morioka S
    • Journal Title

      Frontiers in Neurology

      Volume: 9 Pages: 709-709

    • DOI

      10.3389/fneur.2018.00709

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Manual Dexterity Is a Strong Predictor of Visuo-Motor Temporal Integration in Children2018

    • Author(s)
      Nobusako S, Sakai A, Tsujimoto T, Shuto T, Nishi Y, Asano D, Furukawa E, Zama T, Osumi M, Shimada S, Morioka S, Nakai A
    • Journal Title

      Frontiers in Psychology

      Volume: 9 Pages: 948-948

    • DOI

      10.3389/fpsyg.2018.00948

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] tochastic resonance improves visuomotor temporal integration in healthy young adults.2018

    • Author(s)
      Nobusako S, Osumi M, Matsuo A, Fukuchi T, Nakai A, Zama T, Shimada S, Morioka S.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 12 Pages: e0209382-e0209382

    • DOI

      10.1371/journal.pone.0209382

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Changes in intentional binding effect during a novel perceptual-motor task2018

    • Author(s)
      Morioka S, Hayashida K, Nishi Y, Negi S, Nishi Y, Osumi M, Nobusako S
    • Journal Title

      PeerJ

      Volume: 6 Pages: e6066-e6066

    • DOI

      10.7717/peerj.6066

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sensorimotor incongruence alters limb perception and movement.2017

    • Author(s)
      Osumi M, Nobusako S, Zama T, Taniguchi M, Shimada S, Morioka S.
    • Journal Title

      Hum Mov Sci

      Volume: 57 Pages: 251-257

    • DOI

      10.1016/j.humov.2017.09.003

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of illusory kinesthesia by tendon vibratory stimulation on the postoperative neural activities of distal radius fracture patients.2017

    • Author(s)
      Imai R, Osumi M, Ishigaki T, Kodama T, Shimada S, Morioka S.
    • Journal Title

      Neuroreport

      Volume: 28 Issue: 17 Pages: 1122-1129

    • DOI

      10.1097/wnr.0000000000000874

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between unintentional interpersonal postural coordination produced by interpersonal light touch and the intensity of social relationship.2017

    • Author(s)
      Ishigaki T, Imai R, Morioka S.
    • Journal Title

      Front Psychol

      Volume: 8 Pages: 1993-1993

    • DOI

      10.3389/fpsyg.2017.01993

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Noticing the skill in a motor task enhances sense of agency: Employing intentional binding task2018

    • Author(s)
      Hayashida K, Nishi Y, Masuike A, Osumi M, Morioka S
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Confusion within feedback control between cognitive and perceptual cues in self-other attribution: optimal cue integration in motor control2018

    • Author(s)
      Miyawaki Y, Osumi M, Morioka S
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural mechanism of distorted body perception caused by temporal sensorimotor incongruence2018

    • Author(s)
      Katayama O, Tsukamoto T, Osumi M, Kodama T, Morioka S
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The relationship and difference between delay detection ability and judgment of sense of agency2018

    • Author(s)
      Osumi M, Nobusako S, Zama T, Yokotani N, Shimada S, Morioka S
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Stochastic resonance improves visuomotor temporal integration2018

    • Author(s)
      Nobusako S, Osumi M, Matsuo A, Zama T, Shimada S, Morioka S
    • Organizer
      The 2nd International Symposium on Embodied-Brain Systems Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 感覚の自他区別が運動制御に及ぼす影響:自他区別課題開発のための予備的研究2018

    • Author(s)
      宮脇 裕,大谷武史,林田一輝,大住倫弘,森岡 周
    • Organizer
      第23回日本基礎理学療法学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 運動課題に伴う予測が運動主体感および運動パフォーマンスに与える効果2018

    • Author(s)
      林田一輝,益池章裕,西 祐樹,宮脇 裕,森岡 周
    • Organizer
      第23回日本基礎理学療法学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 歩行と身体意識2018

    • Author(s)
      森岡 周
    • Organizer
      第16回日本神経理学療法学会学術大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 私らしさを取り戻すということ-身体性システム科学の視点から2018

    • Author(s)
      森岡 周
    • Organizer
      第16回日本神経理学療法学会学術大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 失行症と視覚-運動統合障害に共通した責任病巣~映像遅延検出課題とVoxel-based lesion-symptom mappingからの証拠2018

    • Author(s)
      信迫悟志,高村優作,石橋凜太郎,谷頭幸恵,河野正志,富永孝紀,石橋ゆりえ,奥埜博之,大住倫弘,       嶋田総太郎,森岡周
    • Organizer
      第16回日本神経理学療法学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 確率共鳴現象が運動の不器用さに与える即時効果~一症例を通じた検討2018

    • Author(s)
      信迫悟志 ,大住倫弘,松尾 篤 ,古川恵美,嶋田総太郎 ,中井昭夫,森岡 周
    • Organizer
      第5回日本小児理学療法学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 確率共鳴現象は若年健常成人の視覚-運動統合機能を向上する2018

    • Author(s)
      信迫悟志,大住倫弘,松尾篤,福知宇宙,嶋田総太郎,森岡 周
    • Organizer
      第19回日本認知神経リハビリテーション学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 感覚運動の不一致による身体性変容の脳内情報処理メカニズムの検討2018

    • Author(s)
      片山脩,塚元達也,大住倫弘,兒玉隆之,森岡周
    • Organizer
      第40回日本疼痛学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 幻肢痛を含んだ身体性変容のメカニズムとニューロリハビリテーション2018

    • Author(s)
      森岡 周
    • Organizer
      第40回日本疼痛学会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Effects of sharing goals with others on sense of agency and motor performance2018

    • Author(s)
      Hayashida K, Nishi Y, Osumi M, Morioka S.
    • Organizer
      Cognitive Neuroscience Society 2018 Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Sense of agency and motor performance are stronger when an individual is capable of motor prediction.2018

    • Author(s)
      Morioka S, Hayashida K, Nishi Y, Osumi M, Nobusako S.
    • Organizer
      Cognitive Neuroscience Society 2018 Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The influence of sensorimotor incongruence on dysesthesia and motor control.2017

    • Author(s)
      Katayama O, Osumi M, Nishi Y, Takamura Y, Kodama T,Morioka S
    • Organizer
      The 10th Congress of the European Pain Federation
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of illusory kinesthesia by vibratory tendon stimulation on acute pain.2017

    • Author(s)
      Morioka S.
    • Organizer
      PCS International Conference of Neuroscience.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Book] 身体性システムとリハビリテーションの科学2 身体認知2018

    • Author(s)
      近藤 敏之、今水 寛、森岡 周
    • Total Pages
      276
    • Publisher
      東京大学出版会
    • ISBN
      4130644025
    • Related Report
      2018 Annual Research Report
  • [Remarks] 畿央大学ニューロリハビリテーション研究センター

    • URL

      http://www.kio.ac.jp/nrc/

    • Related Report
      2018 Annual Research Report
  • [Remarks] 畿央大学ニューロリハビリテーション研究センターホームページ RESEARCHページ

    • URL

      http://www.kio.ac.jp/nrc/

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2019-12-27  

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