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Predictive coding on auditory processing: spatio-temporal structure of signal flow in whole-cortical electrocorticograms

Publicly Offered Research

Project AreaCorrespondence and Fusion of Artificial Intelligence and Brain Science
Project/Area Number 17H06034
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

小松 三佐子  国立研究開発法人理化学研究所, 脳神経科学研究センター, 研究員 (00525545)

Project Period (FY) 2017-06-30 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2018: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2017: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywords神経科学 / ECoG / マーモセット / 非ヒト霊長類 / 機能ネットワーク / ニューラルネットワーク / 深層学習 / 皮質脳波
Outline of Annual Research Achievements

本研究では、皮質全体から記録された皮質脳波(全脳皮質脳波)を用い予測符号化にかかわる脳内情報処理の時空間構造を明らかにすることを目的とした。
脳は、時々刻々と入力される刺激に対し、絶え間なく般化と予測(predictive coding; PC)を行っている。PCに関する数学的モデルは皮質の層構造や神経細胞レベルの役割を考慮したものまで様々提案されている。近年ではこのようなモデルを機械学習に適用したディープラーニング(深層学習)により大規模データ解析に大きな進展がみられている。しかし脳内での実装についてはまだ不明な点が多く、とくに全脳レベルでの動力学的性質についてはまったくわかっていないのが現状である。
本年度は、聴覚情報の予測符号化にかかわる神経活動を従来の統計学的手法を用いて解析した。その結果、聴覚情報処理には聴覚皮質だけでなく前頭葉・頭頂葉などの脳全域がかかわること、脳内情報処理が並列的に行われている可能性が示唆された。また、予測誤差が生じる場合には、そうでない場合と比較して前頭葉の関与が重要になることが示唆された。さらに、聴覚皮質―前頭葉の機能結合が予測誤差によって動的に修飾されている可能性があることがわかった。これらの結果は予測符号化モデルの新たなアルゴリズム開発へつながることが期待される。

Research Progress Status

平成30年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

平成30年度が最終年度であるため、記入しない。

Report

(2 results)
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (19 results)

All 2019 2018 2017 Other

All Int'l Joint Research (1 results) Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results) Presentation (14 results) (of which Int'l Joint Research: 7 results,  Invited: 4 results) Patent(Industrial Property Rights) (1 results)

  • [Int'l Joint Research] Chinese Academy of Sciences, Shanghai(中国)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Information seeking mechanism of neural populations in the lateral prefrontal cortex2019

    • Author(s)
      Nakamura Kiyohiko、Komatsu Misako
    • Journal Title

      Brain Research

      Volume: 1707 Pages: 79-89

    • DOI

      10.1016/j.brainres.2018.11.029

    • NAID

      120006599952

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chronic Implantation of Whole-cortical Electrocorticographic Array in the Common Marmoset2019

    • Author(s)
      Komatsu Misako、Kaneko Takaaki、Okano Hideyuki、Ichinohe Noritaka
    • Journal Title

      Journal of Visualized Experiments

      Volume: 144 Issue: 144

    • DOI

      10.3791/58980

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Chronically Implantable Bidirectional Neural Interface for Non-human Primates2017

    • Author(s)
      Misako Komatsu, Eriko Sugano, Hiroshi Tomita and Naotaka Fujii
    • Journal Title

      Front Neurosci.

      Volume: 11 Pages: 514-514

    • DOI

      10.3389/fnins.2017.00514

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Cortical information dynamics: Large-scale electrocorticography in common marmosets2019

    • Author(s)
      Komatsu M
    • Organizer
      German-Japanese Workshop on New Directions in System Neuroscience
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cortical information dynamics: Large-scale electrocorticography in common marmosets2019

    • Author(s)
      Komatsu M, Ichinohe N
    • Organizer
      革新脳国際シンポジウムISBM2019
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Wide range cortical interaction during active visual exploration revealed by a whole hemisphere ECoG recording2019

    • Author(s)
      Kaneko T, Komatsu M, Ichinohe N, Okano H
    • Organizer
      第8回 日本マーモセット研究会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Visual mismatch negativity measured from whole-cortical electrocorticograhic arrays in common marmosets2019

    • Author(s)
      Yoshida M, Kaneko T, Komatsu M, Okano H, Ichinohe N
    • Organizer
      第8回 日本マーモセット研究会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Neural dynamics of recurrent active vision2018

    • Author(s)
      Kaneko T, Komatsu M, Ichinohe N, Okano H
    • Organizer
      The 48th Annual Meeting of Society for Neuroscience
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural mechanism for information seeking in monkey prefrontal cortex2018

    • Author(s)
      Nakamura K, Komatsu M
    • Organizer
      The 48th Annual Meeting of Society for Neuroscience
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Predictive coding on auditory processing: Spatio-temporal structure of signal flow in whole-cortical2018

    • Author(s)
      Komatsu M, Ichinohe N
    • Organizer
      The 48th Annual Meeting of Society for Neuroscience
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マーモセット聴覚情報処理における皮質内信号伝搬2018

    • Author(s)
      小松三佐子
    • Organizer
      次世代脳プロジェクト2018年度冬のシンポジウム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Neural dynamics of recurrent active vision2018

    • Author(s)
      Kaneko T, Komatsu M, Ichinohe N, Okano H
    • Organizer
      第2回ヒト脳イメージング研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Effects of ketamine administrations on frequency and duration mismatch activity in common marmosets with electrocorticograms2018

    • Author(s)
      Misako Komatsu
    • Organizer
      The 8th Mismatch Negativity Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Mismatch negativity in common marmosets2018

    • Author(s)
      Noritaka Ichinohe, Misako Komatsu
    • Organizer
      The 41th Annual Meeting of the Japan Neuroscience Society
    • Related Report
      2017 Annual Research Report
  • [Presentation] Effects of ketamine administrations on frequency and duration mismatch activity in common marmosets.2018

    • Author(s)
      Misako Komatsu, Noritaka Ichinohe
    • Organizer
      The 41th Annual Meeting of the Japan Neuroscience Society
    • Related Report
      2017 Annual Research Report
  • [Presentation] An anesthetic dose of ketamine disrupts mismatch activity in common marmosets.2017

    • Author(s)
      Misako Komatsu, Noritaka Ichinohe
    • Organizer
      The 47th Annual Meeting of Society for Neuroscience
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Whole-cortical recordings reveal spreading photo-stimulation effects: A optogenetics study in marmosets.2017

    • Author(s)
      Misako Komatsu, Eriko Sugano, Noritaka Ichinohe, Hiroshi Tomita, Naotaka Fujii
    • Organizer
      The 40th Annual Meeting of the Japan Neuroscience Society
    • Related Report
      2017 Annual Research Report
  • [Patent(Industrial Property Rights)] 皮質脳波電極、脳活動処理システム、及び脳活動処理方法2018

    • Inventor(s)
      小松三佐子、藤井直敬
    • Industrial Property Rights Holder
      小松三佐子、藤井直敬
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-210975
    • Filing Date
      2018
    • Related Report
      2018 Annual Research Report

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Published: 2017-07-04   Modified: 2019-12-27  

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