Understanding of molecular evolution of innate vocalization

• Project Area: Studies of Language Evolution for Co-creative Human Communication
• Project/Area Number: 18H05063
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Research Institution: Tokyo University of Agriculture and Technology
• Principal Investigator: 新村 毅 東京農工大学, (連合)農学研究科(研究院), 准教授 (50707023)
• Project Period (FY): 2018-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2019: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 先天的発声 / ニワトリ / 行動遺伝学 / 集団ゲノミクス / 機能ゲノム / 機能ゲノミクス

Outline of Annual Research Achievements

なぜ地球上で発声が生まれたのか？なぜ動物は種特有の発声ができ、さらに発声を学習することができるようになったのか？という発声・言語進化の根幹を成す問いは、大きな謎に包まれたまま残されており、遺伝子の実体は、いかなる生物においても明らかにされていない。本研究では、多階層的な技術基盤を結集し、先天的発声の制御遺伝子を同定することを目的としていた。2019年度は、先天的発声のパターンの異なるニワトリ品種の全ゲノム情報を集団遺伝的に解析し、QTL解析で得られる情報との統合により、先天的発声を制御しうる候補遺伝子を同定した。

Research Progress Status

令和元年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和元年度が最終年度であるため、記入しない。

Research Products

• [Int'l Joint Research] Uppsala University(スウェーデン)
• [Int'l Joint Research] Columbia University(米国)
• [Journal Article] The quail genome: insights into social behaviour, seasonal biology and infectious disease response (2020)
  • Author(s): Morris KM, Hindle MM, Boitard S, Burt DW, Danner AF, Eory L, Forrest HL, Gourichon D, Gros J, Hillier L, Jaffredo T, Khoury H, Leterrier C, Loudon A, Mason AS, Meddle SL, Minvielle1 F, Minx P, Pitel F, Seiler JP, Shimmura T, Tomlinson C, Vignal A, Webster RG, Yoshimura T, Warren WC, Smith J
  • Journal Title: BMC Biology Volume: 18 Issue: 1 Pages: 1-14
  • DOI: 10.1186/s12915-020-0743-4
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Cholecystokinin induces crowing in chickens (2019)
  • Author(s): Shimmura T, Tamura M, Ohashi S, Sasaki A, Yamanaka T, Nakao N, Ihara K, Okamura S, Yoshimura T.
  • Journal Title: Sci Rep. Volume: 9 Issue: 1 Pages: 3978-3978
  • DOI: 10.1038/s41598-019-40746-9
  • Peer Reviewed / Open Access
• [Journal Article] Seasonally regulation of the lncRNA LDAIR modulates self-protective behaviors during the breeding season. (2019)
  • Author(s): Nakayama T., Shimmura, T., Shinomiya, A., Okimura, K., Takehana,Y., Furukawa, Y., Shimo, T., Senga, T., Nakatsukasa, M., Nishimura, T., Tanaka, M., Okubo, K., Kamei, Y., Naruse, K. and Yoshimura, T.
  • Journal Title: Nature Eco. Evol. Volume: 3 Issue: 5 Pages: 845-852
  • DOI: 10.1038/s41559-019-0866-6
  • Peer Reviewed / Open Access
• [Journal Article] Action spectrum for photoperiodic control of thyroid-stimulating hormone in Japanese quail (Coturnix japonica) (2019)
  • Author(s): Nakane Yusuke、Shinomiya Ai、Ota Wataru、Ikegami Keisuke、Shimmura Tsuyoshi、Higashi Sho-Ichi、Kamei Yasuhiro、Yoshimura Takashi
  • Journal Title: PLOS ONE Volume: 14 Issue: 9 Pages: 845-852
  • DOI: 10.1371/journal.pone.0222106
  • Peer Reviewed / Open Access
• [Journal Article] Seasonal changes in color perception (2018)
  • Author(s): Shimmura T, Nakayama T, Shinomiya A, Yoshimura T
  • Journal Title: General and Comparative Endcrinology Volume: 260 Pages: 171-174
  • DOI: 10.1016/j.ygcen.2017.12.010
  • Peer Reviewed
• [Presentation] Toward animal computer interaction (2019)
  • Author(s): Shimmura T
  • Organizer: The 14th International Conference on Environmental Enrichment
  • Int'l Joint Research / Invited
• [Presentation] Toward multi-level understanding of innate vocalization in chickens (2018)
  • Author(s): Shimmura T
  • Organizer: Songbird workshop
  • Int'l Joint Research / Invited
• [Presentation] 鳥類の先天的発声の制御機構：集団・個体・遺伝子発現・ゲノム (2018)
  • Author(s): 新村毅
  • Organizer: 第43回日本比較内分泌学会大会
  • Invited
• [Remarks] 研究グループHP
  • URL: https://tsuyoshishimmura.wixsite.com/website-1