多重線形代数を基盤とする多次元データ統計解析と計算解剖学への応用

• Project Area: Computational anatomy for computer-aided diagnosis and therapy :Frontiers of medical image sciences
• Project/Area Number: 24103710
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Ritsumeikan University
• Principal Investigator: 陳 延偉 立命館大学, 情報理工学部, 教授 (60236841)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000); Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2012: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
• Keywords: 多重線形 / 腹部複数臓器 / スパース / Low-rank / 局所解析 / ボリューム / 医用画像 / テンプレートマッチング / パターン認識

Research Abstract

医用ボリュームデータをテンソルとしてそのまま取り扱うことができる、多重線形テンソルコーディング法（LTC: Linear Tensor Coding）を開発した。提案法では、まず入力テンソルから先行研究で開発したGND-PCAでランク１テンソル基底（第１基底）を求め、次に残差テンソル（入力テンソルと再構成テンソルとの差）から第2、第3、などの基底を階層的に求めていく。残差テンソルのノルムがある閾値r(近似精度を表すパラメータ)より小さくなるまで高次の基底を求めていく。入力テンソルは、これらのテンソル基底の線形結合で表される。
先行研究のGND-PCAに比べ、LTCは以下のような二つの特徴をもつ。
特徴１：学習サンプル（入力テンソル）から求められた第1基底は、入力群の最も分散の大きい成分（低周波成分）を表しており、第2基底以降は、残差テンソル（入力テンソルと再構成テンソルとの差）から求められているので、入力テンソルの特徴的なパターン（高周波成分）を表しており、特定な意味・効果を表している。基底の係数はそれらの特定効果の尺度として用いることができる．病気の特定や診断支援が期待できる。
特徴2: 基底の数は近似精度を表すパラメータrで自動的に決まる。
また、本研究では、理論開発だけだはなく、肝臓画像データにも適用し、正常か異常かの分類実験において、従来法よりすぐれた結果がえられたので、支援診断に有効であることを示した。その成果は国際学術誌Computational and Mathematical Methods in Medicineに論文を掲載した。

Current Status of Research Progress

Reason

25年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

25年度が最終年度であるため、記入しない。

Research Products

• [Journal Article] Computer-Aided Diagnosis and Quantification of Cirrhotic Livers Based on Morphological Analysis and Machine Learning (2013)
  • Author(s): Yen-Wei Chen, Jie Luo, Chunhua Dong, Xianhua Han, Tomoko Tateyama, Akira Furukawa, Shuzo Kanasaki
  • Journal Title: Computational and Mathematical Methods in Medicine Volume: Volume 2013 Pages: 1-8
  • DOI: 10.1155/2013/264809
  • Peer Reviewed
• [Journal Article] Statistical Shape Model of the Liver and Its Application to Computer Aided Diagnosis of Liver Cirrhosis (2013)
  • Author(s): Mei Uetani, Tomoko Tateyama, Shiya Kohara, Hitetoshi Tanaka, Xian-hua Han, Shuzo Kanasaki, Akira Furukawa and Yen-Wei Chen
  • Journal Title: IEEJ Trans. on Electronice, Information and Systems Volume: Vol.133,No.11 Pages: 2037-2043
  • NAID: 130003382761
  • Peer Reviewed
• [Journal Article] Novel Liver Visualization and Surgical Simulation System (2013)
  • Author(s): Kaibori M, Chen YW, Matsui K, Ishizaki M, Tsuda T, Nakatake R, Sakaguchi T, Matsushima H, Miyawaki K, Shindo T, Tateyama T, Kwon AH
  • Journal Title: J Gastrointest Surg Volume: Vol.17 Pages: 1422-1428
  • Peer Reviewed
• [Journal Article] Segmentation of Liver in Low-contrast Images Using K-Means Clustering and Geodesic Active Contour Algorithms (2013)
  • Author(s): A. H. Foruzan, Y.-W. Chen at. al.,
  • Journal Title: IEICE Trans Volume: Vol.E96-D Pages: 798-807
  • Peer Reviewed
• [Journal Article] Application of Statistical Shape Model of the Liver in Classification of Cirrhosis (2013)
  • Author(s): Yen-Wei Chen, Mei Uetani, Shinya Kohara, Tomoko Tateyama, Xian-Hua Han, Akira Furukawa, Shuzo Kanasaki
  • Journal Title: International Journal of Digital Content Technology and its Applications Volume: Vol. 7, No. 9 Pages: 477-484
  • Peer Reviewed
• [Journal Article] Statistical Texture Modeling for Medical Volume Using Linear Tensor Coding (2013)
  • Author(s): Junping Deng, Xu Qiao and Yen-Wei Chen
  • Journal Title: Computational and Mathematical Methods in Medicine Volume: Volume 2013 Pages: 1-10
  • Peer Reviewed
• [Journal Article] Generalized N-Dimensional Independent Component Analysis and Its Application to Multiple Feature Selection and Fusion for Image Classification (2013)
  • Author(s): Danni Ai, Guifang Duan, Xianhua Han, Yen-Wei Chen
  • Journal Title: Neurocomputing Volume: Vol.103 Pages: 186-197
  • Peer Reviewed
• [Journal Article] 患者に特化した肝臓情報とその脈管分布可視化及び対話かつ直感的な手術支援システムの構築 (2013)
  • Author(s): 健山智子、海堀昌樹、進藤典、Amir Hossein Foruzan, 林正倫、宮脇康介、津田匠、松井康輔、權雅憲、韓先花、姜彗研、陳延偉
  • Journal Title: Medical Imaging Technology Volume: Vol.31, No.3 Pages: 176-188
  • Peer Reviewed
• [Journal Article] Multilinear Supervised Neighborhood Embedding of Local Descriptor Tensor for Scene/object Recognition (2012)
  • Author(s): Xian-Hua Han and Yen-Wei Chen
  • Journal Title: IEEE Trans. on Image Processing Volume: Vol.21, No.3 Pages: 1314-1326
  • Peer Reviewed
• [Journal Article] Application of ICA to X-ray coronary digital subtraction angiography (2012)
  • Author(s): Songyuan Tang, Yongtian Wang, Yen-Wei Chen
  • Journal Title: Neurocomputing Volume: Vol.79 Pages: 168-172
  • Peer Reviewed
• [Journal Article] Analysis of CT Images of Liver for Surgical Planning (2012)
  • Author(s): Amir H. Foruzan, Yen-Wie Chen, Reza A. Zoroofi, Masaki Kaibori
  • Journal Title: American Journal of Biomedical Engineering Volume: Vol.2, No.2 Pages: 23-28
  • Peer Reviewed
• [Journal Article] Hybrid Particle Swarm Optimization and Its Application to Multimodal 3D Medical Image Registration (2012)
  • Author(s): Chen-Lun Lin, Aya Mimori, and Yen-Wei Chen
  • Journal Title: Computational Intelligence and Neuroscience Volume: Vol. 2012 Pages: 1-7
  • Peer Reviewed
• [Presentation] Super-Resolution of MR Volumetric Images Using Sparse Representation and Self-Similarity (2012)
  • Author(s): Yutaro Iwamoto, Xian-Hua Han, So Sasatani, Kazuki Taniguchi, Wei Xiong and Yen-Wei Chen
  • Organizer: Proc. of 21st International Conference on Pattern Recognition (ICPR 2012)
  • Place of Presentation: 茨城県, つくば国際会議場
  • Year and Date: 2012-11-15
• [Presentation] Group Sparse Representation of Adaptive Sub-Domain Selection for Image Classification (2012)
  • Author(s): Xian-Hua Han, Xu Qiao and Yen-Wei Chen
  • Organizer: Proc. of 21st International Conference on Pattern Recognition (ICPR 2012)
  • Place of Presentation: 茨城県, つくば国際会議場
  • Year and Date: 2012-11-13
• [Presentation] Multiple Feature Selection and Fusion Based on Generalized N-Dimensional Independent Component Analysis (2012)
  • Author(s): Danni Ai, Guifang Duan, Xianhua Han and Yen-Wei Chen
  • Organizer: Proc. of 21st International Conference on Pattern Recognition (ICPR 2012)
  • Place of Presentation: 茨城県, つくば国際会議場
  • Year and Date: 2012-11-13
• [Presentation] K-CPD: Learning of Overcomplete Dictionaries for Tensor Sparse Coding (2012)
  • Author(s): Guifang Duan, Hongcui Wang, Zhenyu Liu, Junping Deng and Yen-Wei Chen
  • Organizer: Proc. of 21st International Conference on Pattern Recognition (ICPR 2012)
  • Place of Presentation: 茨城県, つくば国際会議場
  • Year and Date: 2012-11-12
• [Presentation] A New Linear Coding Algorithm for Efficient Multi-dimensional Data Representation without Data Expansion (2012)
  • Author(s): Xu Qiao, Xuantao Su, Xianhua Han and Yen-Wei Chen
  • Organizer: Proc. of 2012 International Conference on New Trends in Information Science, Service Science and Data Mining (ISSDM2012)
  • Place of Presentation: Taiwan, Taipei
  • Year and Date: 2012-10-24
• [Presentation] Computational Anatomy Models for Medical Image Understanding (2012)
  • Author(s): Yen-Wei Chen
  • Organizer: 2012 International Conference on New Trends in Information Science, Service Science and Data Mining (ISSDM2012)
  • Place of Presentation: Taiwan, Taipei
  • Year and Date: 2012-10-23
• [Presentation] 顔面神経麻痺の客観的評価のための画像特徴量の検討 (2012)
  • Author(s): 木原裕太・段桂芳・瀬尾昌孝・松代直樹・陳延偉
  • Organizer: 第17回日本顔学会大会
  • Place of Presentation: 東京都, 東京電機大学
  • Year and Date: 2012-10-14
• [Presentation] 超解像イメージング数理の基礎と最新動向 (2012)
  • Author(s): 陳 延偉
  • Organizer: 第31回日本医用画像工学会大会
  • Place of Presentation: 北海道, ＪＡ北海道厚生連札幌厚生病院
  • Year and Date: 2012-08-04
• [Presentation] A Novel Components Selection Method in Statistical Shape Model for Computer-aided Diagnosis and It's Application for Assisting Cirrhosis Diagnosis (2012)
  • Author(s): Jie Luo・Xian-hua Han・Shinya Kohara・Tomoko Tateyama・Akira furukawa・Shuzo Kanasaki・Yen-Wei Chen
  • Organizer: 信学技報
  • Place of Presentation: 愛知県, 名古屋工業大学
  • Year and Date: 2012-05-17
• [Presentation] SPHARMベース統計形状モデルと点分布ベース統計形状モデルとの性能比較 (2012)
  • Author(s): 健山智子・桶川萌・小原伸哉・韓先花・古川顕・金崎周造・陳 延偉
  • Organizer: 信学技報
  • Place of Presentation: 愛知県, 名古屋工業大学
  • Year and Date: 2012-05-17
• [Presentation] Sparse Dictionary Representation and Propagation for MRI Volume Super-Resolution (2012)
  • Author(s): Xianhua Han・Yen-Wei Chen
  • Organizer: 信学技報
  • Place of Presentation: 愛知県, 名古屋工業大学
  • Year and Date: 2012-05-17
• [Presentation] Pilot Study of Applying Shape Analysis to Liver Cirrhosis Diagnosis
  • Author(s): Jie Luo, Yen-Wei Chen, Tomoko Tateyama, Xian-Hua Han, Akira Furukawa, Shuzo Kanasaki
  • Organizer: Proceedings of IEEE International Conference on Image Processing (ICIP2013)
  • Place of Presentation: Melbourne, Australia
• [Presentation] Computer-Aided Liver Surgical Planning System Using CT Volumes
  • Author(s): Yen-Wei Chen, Masaki Kaibori, Kousuke Miyawaki, Tsukasa Shindo, Amir H. Foruzan, Tomoko Tateyama, Xian-Hua Han, Kosuke Matsui, Takumi Tsuda, A-Hon Kwon
  • Organizer: Proc. of IEEE EMBC2013
  • Place of Presentation: Osaka International Convention Center,Osaka, Japan
• [Presentation] A Preliminary Study on Multi-Touch Based Medical Image Analysis and Visualization System
  • Author(s): Wang Jian, Hua-Wei Tu, Xian-Hua Han, Tomoko Tateyama, Yen-Wei Chen
  • Organizer: 2013 6th International Conference on BioMedical Engineering and Informatics (BMEI 2013)
  • Place of Presentation: Hangzhou, China
• [Presentation] Automated Assessment of Small Bowel Motility Function Based on Three-dimensional Zero-mean Normalized Cross Correlation
  • Author(s): Ayako Taniguchi, Yen-Wei Chen, Akira Furukawa, Shuzo Kanasaki, Tomoko Tateyama
  • Organizer: 2013 6th International Conference on BioMedical Engineering and Informatics (BMEI 2013)
  • Place of Presentation: Hangzhou, China
• [Presentation] Nonrigid Registration for Evaluating Locoregional Therapy of Hepatocellular Carcinoma
  • Author(s): Chunhua Dong, Toshihito Seki, Ryosuke Inoguchi, Chen-lun Lin, Xian-Hua Han, Yen-Wei Chen
  • Organizer: 2013 6th International Conference on BioMedical Engineering and Informatics (BMEI 2013)
  • Place of Presentation: Hangzhou, China
• [Presentation] Robust Isotropic Super-Resolution by maximizing a Laplace posterior for MRI Volumes
  • Author(s): Xian-Hua Han, Yutaro Iwamoto, Akihiko Shino and Yen-Wei Chen
  • Organizer: 2014 SPIE Medical Imaging
  • Place of Presentation: San Diego, USA
• [Presentation] フレーム間差分法による小腸収縮運動の自動解析
  • Author(s): 谷口絢子・古川顕・健山智子・武星・佐藤滋高・金崎周造・陳 延偉
  • Organizer: 電子情報通信学会医用画像研究会MI2013-5
  • Place of Presentation: 愛知県／名古屋工業大学
• [Presentation] 球面調和関数による人体臓器の 3 次元形状表現の 性能評価と統計形状モデル構築
  • Author(s): 健山智子, 上谷芽衣, 小原伸哉, 韓先花, 桶川萌, 金崎周造, 古川顕, 堀雅敏, 富山憲幸, 陳 延偉
  • Organizer: 第32回日本医用画像工学大会
  • Place of Presentation: 東京都／日本科学未来館／産業技術総合研究所臨海副都心センター
• [Presentation] 統計形状モデルの構築と肝硬変症支援診断への応用
  • Author(s): 上谷芽衣, 健山智子, 小原伸哉, 韓先花, 金崎周造, 古川顕, 陳延偉
  • Organizer: 第32回日本医用画像工学大会
  • Place of Presentation: 東京都／日本科学未来館／産業技術総合研究所臨海副都心センター
• [Presentation] ワーピングを用いた顔面神経麻痺のシミュレーション
  • Author(s): 計田真夕、瀬尾昌孝、松代直樹、陳延偉
  • Organizer: 第18回日本顔学会大会（フォーラム顔学2013）
  • Place of Presentation: 宮城県／東北大学
• [Presentation] 確率モデルを用いたCT画像からの腫瘍候補検出
  • Author(s): 今野悠, 韓先花, 陳延偉
  • Organizer: 平成２５年度電気関係学会関西連合大会
  • Place of Presentation: 大阪府／大阪電気通信大学
• [Presentation] 遺伝子関連研究のための顔面形態解析 第2報－非剛体位置合わせ不要な対応付け法－
  • Author(s): 中津美冴, 韓先花, 瀬尾昌孝，健山智子, 木村亮介, 陳延偉
  • Organizer: 平成２５年度電気関係学会関西連合大会
  • Place of Presentation: 大阪府／大阪電気通信大学
• [Presentation] Total Variation正則化を用いたマルチフレーム超解像技術
  • Author(s): 近藤佑斗, 野島優補, 谷口和輝, 韓先花, 陳延偉
  • Organizer: 平成２５年度電気関係学会関西連合大会
  • Place of Presentation: 大阪府／大阪電気通信大学
• [Presentation] Sparse and Low-Rank Decomposition for Robust Medical Image Registration
  • Author(s): Junping Deng, Xianhua Han, Gang Xu and Yen-Wei Chen
  • Organizer: The 9th Joint Workshop on Machine Perception and Robotics
  • Place of Presentation: 京都府/立命館大学朱雀キャンパス
• [Book] Proceedings of 2012 International Conference on New Trends in Information Science, Service Science and Data Mining (2012)
  • Author(s): hien-wen Shen, Sy-Yen Kuo, Kae Dal Kwack, Yen-Wei Chen, Ping-Yu Hsu and Franz Ko (Eds)
  • Publisher: IEEE Press
• [Book] (Chapter 6) Liver Tumor Detection in CT Images by Adaptive Contrast Enhancement and the EM/MPM Algorithm, Liver (2012)
  • Author(s): Yu Masuda, Tomoko Tateyama, Wei Xiong, Jiayin Zhou, Makoto Wakamiya, Syuzo Kanasaki, Akira Furukawa and Yen-Wei Chen
  • Publisher: TumorsAlexander Julianov Ed., InTech, (Croatia)
• [Book] (Chapter 5) Multilinear Supervised Neighborhood Preserving Embedding Analysis of Local Descriptor Tensor, Principal Component Analysis (2012)
  • Author(s): Xian-Hua Han and Yen-Wei Chen
  • Publisher: Parinya Sanguansat Ed., InTech, (Croatia）
• [Book] (Chapter 8) Construction of Digital Statistical Atlases of the Liver and their Applications to Computer-Aided Diagnosis, Technological Advancements in Biomedicine for Healthcare Applications (2012)
  • Author(s): Yen-Wei Chen
  • Total Pages: 12
  • Publisher: Jinglong Wu Ed., IGI Global (PA, USA)
• [Remarks] 研究者学術情報データベース陳延偉
  • URL: http://research-db.ritsumei.ac.jp/Profiles/28/0002774/profile.html
• [Remarks] Intelligent Image Processing Lab
  • URL: http://www.iipl.is.ritsumei.ac.jp/index.html