Development of a comprehensive and accurate absolute protein and phosphorylation quantification method applicable to diverse organisms

Publicly Offered Research

Project Area	chronoproteinology: Protein Machinery that drives "time" on various time scales
Project/Area Number	25H02462
Research Category	Grant-in-Aid for Transformative Research Areas (A)
Allocation Type	Single-year Grants
Review Section	Transformative Research Areas, Section (III)
Research Institution	Hiroshima University
Principal Investigator	内田康雄広島大学, 医系科学研究科(薬), 教授 (70583590)
Project Period (FY)	2025-04-01 – 2027-03-31
Project Status	Granted (Fiscal Year 2025)
Budget Amount *help	¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000) Fiscal Year 2025: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Keywords	網羅的な絶対定量法 / 生物横断的 / イオン液体 / PCT / qGAP法
Outline of Research at the Start	独自の技術を融合させることによって、動物・植物を問わずどんな生物にも適用可能で、タンパク質の絶対存在量（mole）を正確に（真の量にいかに近く）、かつ、その時間経過に伴う変化を高精度（微細な量的変化も確実）に定量できる網羅的なタンパク質絶対定量法を開発することを目指します。