電極間伸長固定されたDNA/導電性高分子高次組織体単一鎖の光電機能

• Project Area: Molecular Architectonics: Orchestration of Single Molecules for Novel Function
• Project/Area Number: 26110503
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Chiba University
• Principal Investigator: 小林 範久 千葉大学, 融合科学研究科(研究院), 教授 (50195799)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 先端機能デバイス / ナノバイオ / 生体材料 / 単一鎖機能 / 分子ネットワーク / DNA / 分子ワイヤー / 静電伸長 / 光電機能 / 電気化学発光

Outline of Annual Research Achievements

単一鎖レベルで，（光吸収・電荷分離・電荷輸送）過程や（電荷輸送・電荷再結合・発光）過程などの高次機能を有するDNA高次組織体を電極間に伸長固定し，単一鎖レベルでの高次構造と光電機能の関係から，分子レベルでのDNA物性の理解を深め，革新的な光電機能を示す次世代分子デバイス創製を目的としている。平成27年度は，まず，前年度用いた電極間隔25μm櫛形電極が，単一鎖からなるDNAナノワイヤーの位置選択的構築には困難であったため，電極間隔3μmの対向尖端形状電極を用い，単一鎖DNAナノワイヤー作成を行った。一方で，光電機能単一鎖デバイス実現のための基礎知見収集を目的として，DNAナノワイヤーに光機能Ru錯体，さらには導電性高分子ポリアニリン(PAn)を複合したナノワイヤーの電気物性を測定した。
結果として、
１）基板上に形成された，鋭角の先端を持つ金電極が先端間隔3μmで対向する対向尖端形状電極間にDNA 希薄溶液を滴下し，電極間に高周波高電界を与えることで，DNAの電極間単一鎖伸長固定を行った。電界が先端に集中するため，電極間隔25μm櫛形電極よりも条件設定が困難であり，周波数，印加電圧を幅広く検討することで，単一鎖で先端電極間に電界伸長されたDNAナノワイヤーの構築が可能であることを確認した。しかしながらまだ再現性に乏しく，高効率な方法論の確立が必要である。
２）前年度に電極間隔25μm櫛形電極間に構築したDNAナノワイヤーとそれに光機能性Ru錯体を導入したナノワイヤー，さらにはPAnを複合したナノワイヤーの電流電圧特性を評価した。電流値はRu錯体複合により大きく上昇したが，Ru錯体導入後とPAn導入後の電流値には大きな差が認められなかった。AFMより，PAn複合ナノワイヤー上にPAnの凝集構造が多く認められており，導電パスの不連続性が原因であることが明らかとなった。

Research Progress Status

27年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

27年度が最終年度であるため、記入しない。

Research Products

• [Journal Article] An Electrochemically-Driven Dual-Mode Display Device with Both Reflective and Emissive Modes Using Poly( p-phenylenevinylene) Derivatives (2016)
  • Author(s): S. Tsuneyasu, L. Jin, K. Nakamura and N. Kobayashi
  • Journal Title: Jpn. J. Appl. Phys. Volume: 55 Issue: 4 Pages: 041601-041601
  • DOI: 10.7567/jjap.55.041601
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Temperature Dependence of Transfer Characteristics of OTFT Memory Based on DNA-CTMA Gate Dielectric (2016)
  • Author(s): L. Liang, Y. Mitsumura, K. Nakamura, S. Uemura, T. Kamata and N. Kobayashi
  • Journal Title: Organic Electronics Volume: 28 Pages: 294-298
  • DOI: 10.1016/j.orgel.2015.11.003
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Electrochemical Luminescence Modulation in a Eu(III) Complex-Modified TiO2 Electrode (2015)
  • Author(s): K. Kanazawa, K. Nakamura and N. Kobayashi
  • Journal Title: J. Mater. Chem. C Volume: 3 Issue: 27 Pages: 7135-7142
  • DOI: 10.1039/c4tc02996h
  • Peer Reviewed
• [Journal Article] Stretching and Immobilization of Photo-Electro Functional Nanowires Consisted of DNA and Functional Molecules (2015)
  • Author(s): N. Kobayashi, K. Nakamura, M. Nishizawa, R. Son, S. Inoue and Y. Nishiyama
  • Journal Title: Nonl. Opt. Quantum. Opt. Volume: 47 Pages: 161-174
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Stretching and Immobilization of Photo-Electro Functional Nanowires Consisted of DNA and FunctionalMolecules (2015)
  • Author(s): Norinisa Kobayashi, Kazuki Nakamura, Makoto Nishizawa, Rena Son, ShintaroInoue and Yuki Nishiyama
  • Journal Title: Nonlinear Optics, Quantum Optics Volume: 47
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] High-Contrast Electroswitching of Emission and Coloration Based on Single-Molecular Fluoran Derivatives (2015)
  • Author(s): Kenji kanazawa, Kazuki Nakamura and Norihisa Kobayashi
  • Journal Title: Journal of Physical Chemistry A Volume: 118 Issue: 31 Pages: 6026-6033
  • DOI: 10.1021/jp5060588
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Analysis of Charge Transport Property in Polymer Film Containing Triphenylamine Derivative Film using Impedance Spectroscopy (2014)
  • Author(s): Keita Ishii, Kazuki Nakamura and Norihisa Kobayashi,
  • Journal Title: NIHON GAZO GAKKAISHI (Journal of the Imaging Society of Japan) Volume: 53 Issue: 4 Pages: 259-264
  • DOI: 10.11370/isj.53.259
  • NAID: 130004678689
  • ISSN: 1344-4425, 1880-4675
  • Peer Reviewed
• [Journal Article] Effect of amide bond in gate dielectric polymers on memory performance of organic field-effect transistors (2014)
  • Author(s): Heisuke Sakai, Hea-Jeong Cheong, Takehito Kodzasa, Hideo Tokuhisa, Kazuhiko Tokoro, Manabu Yoshida, Taihei Ikoga, Kazuki Nakamura, Norihisa Kobayashi and Sei Uemura
  • Journal Title: Japanese Journal of Applied Physics Volume: 53 Issue: 5S3 Pages: 05HB13-05HB13
  • DOI: 10.7567/jjap.53.05hb13
  • NAID: 210000143979
  • Peer Reviewed
• [Presentation] Photoelectronic functional DNA nanowires stretched between electrodes toward DNA molecular device (2015)
  • Author(s): N. Kobayashi, T. Kunikyo and K. Nakamura
  • Organizer: Pacifichem 2015
  • Place of Presentation: Honolulu (USA)
  • Year and Date: 2015-12-15
  • Int'l Joint Research
• [Presentation] DNA/Ru(bpy)32+ Complex as a Novel AC-Driven Electrochemiluminescent Material (2015)
  • Author(s): N. Kobayashi, R. Takahashi, S. Tsuneyasu and K. Nakamura
  • Organizer: 2015 MRS Fall Meeting and Exhibit
  • Place of Presentation: Boston (USA)
  • Year and Date: 2015-11-29
  • Int'l Joint Research
• [Presentation] DNA as a novel material toward electronics and photonics (2015)
  • Author(s): N. Kobayashi
  • Organizer: SPIE Security and Diffence 2015
  • Place of Presentation: Toulouse (France)
  • Year and Date: 2015-09-21
  • Int'l Joint Research / Invited
• [Presentation] Quick response AC-operated Electrochemiluminescent Cell with DNA/Ru complex (2015)
  • Author(s): N. Kobayashi
  • Organizer: SPIE Optics + Photonics 2015
  • Place of Presentation: San Diego (USA)
  • Year and Date: 2015-08-09
  • Int'l Joint Research / Invited
• [Presentation] Improvement of photopysical properties of emissive molecules in DNA matrix (2014)
  • Author(s): Norihisa Kobayashi, Wataru Watanabe and Kazuki Nakamura
  • Organizer: SPIE Security&Diffince
  • Place of Presentation: Amsterdam, Neitherland
  • Year and Date: 2014-09-22 – 2014-09-25
  • Invited
• [Presentation] Reflective and emissive dual mode display with electrochromism and electrochemiluminescence (2014)
  • Author(s): Norihisa Kobayashi
  • Organizer: International caparica conference on chromogenics and emissivematerials
  • Place of Presentation: Caparica, Portugal
  • Year and Date: 2014-09-08 – 2014-09-10
  • Invited
• [Presentation] BioTFT memory with DNA gate dielectric and its thermal property (2014)
  • Author(s): Norihisa Kobayashi, Kazuki Nakamura, Sei Uemura and Toshihide Kamata
  • Organizer: SPIE optics+Photonics
  • Place of Presentation: San Diego, USA
  • Year and Date: 2014-08-17 – 2014-08-21
  • Invited
• [Book] Application of DNA to Materials Science 2 in "DNA Engineering : Properties and Applications" (2016)
  • Author(s): H. Mizoguchi and H. Sakamoto (Eds.), N. Kobayashi and K. Nakamura
  • Publisher: Pan Stanford Publishing
• [Book] DNA electronics and photonics in "Electronic Processes in Organic Electronics" (2015)
  • Author(s): H. Ishii, K. Kudo, T. Nakayama and N. Ueno (Eds.), N. Kobayashi and K. Nakamura
  • Total Pages: 432
  • Publisher: Springer
• [Book] “Application of DNA to Materials Science 2” in "DNA Engineering : Properties and Applications" (2015)
  • Author(s): Norihisa Kobayashi and Kazuki Nakamura
  • Publisher: Springer
• [Book] “Electrochemical Luminescence” in "Encyclopedia of Applied Electrochemistry" (2014)
  • Author(s): Norihisa Kobayashi
  • Total Pages: 2169
  • Publisher: Springer
• [Book] “DNA electronics and photonics” in "Electronic Processes in Organic Electronics: Bridging Nanostructure, ElectronicStates and Device Properties" (2014)
  • Author(s): Norihisa Kobayashi and Kazuki Nakamura
  • Total Pages: 432
  • Publisher: Springer
• [Remarks] http://photo-m.tp.chiba-u.jp/i-poly/
• [Patent(Industrial Property Rights)] 発光材料及びこれを用いた表示装置 (2014)
  • Inventor(s): 小林範久，中村一希
  • Industrial Property Rights Holder: 小林範久，中村一希
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2014-178604
  • Filing Date: 2014-09-02