Plasma Science Innovation
Compiling the Research Achievements
Project Area | Plasma medical innovation |
Project/Area Number |
17H06075
|
Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
|
Allocation Type | Single-year Grants |
Research Institution | Nagoya University |
Principal Investigator |
堀 勝 名古屋大学, 工学研究科, 教授 (80242824)
|
Co-Investigator(Kenkyū-buntansha) |
田中 昭代 九州大学, 医学研究院, 講師 (10136484)
池原 譲 国立研究開発法人産業技術総合研究所, 生命工学領域, 上級主任研究員 (10311440)
節原 裕一 大阪大学, 接合科学研究所, 教授 (80236108)
|
Project Period (FY) |
2017-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
|
Keywords | プラズマ / プラズマ医療科学 / プラズマがん治療 / プラズマ止血 / プラズマ遺伝子注入 / プラズマ遺伝子導入 |
Outline of Annual Research Achievements |
本研究領域ではプラズマ科学を中核に据え,医学・分子生物学と融合した未踏の新領域「プラズマ医療科学」の創成を目的に推進し,研究項目A01:医療プラズマエレクトロニクス,A02:プラズマ分子生物科学,A03:プラズマ臨床科学とし,A01では医療プラズマ源の「診る・作る」,A02ではプラズマと生体の相互作用を「理解する」,A03では医療プラズマを臨床的に「使う」ための安全性に関する学術的基盤構築を展開してきた.A01,A02,A03は高度な連携研究が進み,プラズマ,医学,生物学の異分野横断型の統合による新学術領域「プラズマ医療科学」が構築された.成果の戦略的公表や破壊的イノベーションと産業への展開,永続的発展のためのインフラ整備やグローバルな独創的な研究スキームを構築した.(1)平成28年度までの科学的成果を総括し,平成29年度には分野横断型のカテゴリ毎のレビュー論文として公表できた.また国内外の学会で「プラズマ医療科学の創成」を総括した研究成果を発表した.平成28年度までのアウトリーチ活動を継続して,平成29年度にも高校生向けの市民講座「のぞいてみよう!プラズマと生物と医療のふしぎな世界」や毎月開催でサイエンスカフェ等を進めてきた.これらは市民との永続的なネットワークとして継続,新学術領域「プラズマ医療科学の創成」で得られた成果を社会・国民に発信していく組織を作った.(2)A01からA03の研究項目を横断する組織として,いくつかチームラボや協調研究を立ち上げて,多様な研究者からなる連携研究の強化を図ってきた.また,名大,九大,産総研に設立した拠点ごとに研究教育を推進した.また,世界の研究者とともに我が国発の「プラズマ医療科学」を提言するとともに,国際学術書籍(教科書)「Plasma Medical Science」の出版を行った(2018年11月刊行予定).
|
Research Progress Status |
29年度が最終年度であるため、記入しない。
|
Strategy for Future Research Activity |
29年度が最終年度であるため、記入しない。
|
Report
(1 results)
Research Products
(60 results)
-
-
-
-
-
-
-
-
[Journal Article] Free radical generation by non-equilibrium atmospheric pressure plasma in alcohol-water mixtures. An EPR-spin trapping study2018
Author(s)
Hidefumi Uchiyama, Qing-Li Zhao, Gabor Andocs, Nobuyuki Nojima, Keigo Takeda, Murali Krishna, Yuji Matsuya, Kenji Ishikawa, Masaru Hori, Kyo Noguchi, and Takashi Kondo
-
Journal Title
J. Phys.D: Appl. Phys.
Volume: 51
Issue: 11
Pages: 026201-026201
DOI
Related Report
Peer Reviewed / Int'l Joint Research
-
-
-
[Journal Article] Clinical Experience with Cold Plasma in the Treatment of Locally Advanced Head and Neck Cancer2018
Author(s)
H-R. Metelmann, C. Seebauer, V. Miller, A. Fridman, G. Bauer, D. B. Graves, J-M. Pouvesle, R. Rutkowski, M. Schuster, S. Bekeschus, K. Wende, K. Masur, S. Hasse, T. Gerling, Masaru Hori, Hiromasa Tanaka, E. H. Choi, K-D. Weltmann, P. H. Metelmann, D. D. Von Hoff, T. von Woedtke
-
Journal Title
Clinical Plasma Medicine
Volume: 9
Pages: 6-13
DOI
Related Report
Peer Reviewed / Int'l Joint Research
-
-
-
-
[Journal Article] Intraperitoneal Administration of Plasma-Activated Medium: Proposal of a Novel Treatment Option for Peritoneal Metastasis From Gastric Cancer2017
Author(s)
Shigeomi Takeda, Suguru Yamada, Norifumi Hattori, Kae Nakamura, Hiromasa Tanaka, Hiroaki Kajiyama, Mitsuro Kanda, Daisuke Kobayashi, Chie Tanaka, Tsutomu Fujii, Michitaka Fujiwara, Masaaki Mizuno, Masaru Hori, Yasuhiro Kodera
-
Journal Title
Annals of Surgical Oncology
Volume: 24
Issue: 5
Pages: 1188-1194
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Intraperitoneal Treatment With Plasma-Activated Liquid Inhibits Peritoneal Metastasis In Ovarian Cancer Mouse Model2018
Author(s)
Kae Nakamura, Hiroaki Kajiyama, Yang Peng, Fumi Utsumi, Nobuhisa Yoshikawa, Hiromasa Tanaka, Masaaki Mizuno, Shinya Toyokuni, Masaru Hori, and Fumitaka Kikkawa
Organizer
5th International Workshop on Plasma for Cancer Treatment, Greifswald, March 21-22, 2018
Related Report
Int'l Joint Research
-
[Presentation] Similarities And Differences In The Cellular Resposnses Between Plasma-Activated Medium-Treated Glioblastomas And Plasma-Activated Ringer’s Lactate Solution-Treated Glioblastomas2018
Author(s)
Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Keigo Takeda, Hiroki Kondo, Makoto Sekine, Hiroshi Hashizume, Kae Nakamura, Hiroaki Kajiyama, Yasumasa Okazaki, Shinya Toyokuni, Shinichi Akiyama, Shoichi Maruyama, Fumitaka Kikkawa, and Masaru Hori
Organizer
5th International Workshop on Plasma for Cancer Treatment, Greifswald, March 21-22, 2018
Related Report
Int'l Joint Research
-
[Presentation] Plasma-Activated Medium Inhibites Metastatic Activities Of Ovarian Cancer Cells In Vitro Via Repressing Mapk Pathway2018
Author(s)
Yang Peng, Hiroaki Kajiyama, Kae Nakamura, Fumi Utsumi, Nobuhisa Yoshikawa, Hiromasa Tanaka, Masaaki Mizuno, Shinya Toyokuni, Masaru Hori, and Fumitaka Kikkawa
Organizer
5th International Workshop on Plasma for Cancer Treatment, Greifswald, March 21-22, 2018
Related Report
Int'l Joint Research
-
[Presentation] Plasma-activated medium and plasma-activated Ringer’s lactate solution exhibited anti-tumor effects through different mechanisms2018
Author(s)
Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Hiroki Kondo, Keigo Takeda, Hiroshi Hashizume, Kae Nakamura, Fumi Utsumi, Hiroaki Kajiyama, Yasumasa Okazaki, Shinya Toyokuni, Fumitaka Kikkawa, and Masaru Hori
Organizer
ISPLASMA - 10th International Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials, March 04-08, 2018
Related Report
Int'l Joint Research
-
-
[Presentation] Time evolution of reactive oxygen nitrogen species in plasma-activated essential media and water2017
Author(s)
Timothy Ryan Brubaker, Kenji Ishikawa, K. Takeda, H. Hashizume, H. Tanaka, H. Kondo, M. Sekine, M. Hori
Organizer
ICOPS 2017 - 44th Annual International Conference on Plasma Science May 21-25, 2017. Atlantic City, New Jersey, USA.
Related Report
Int'l Joint Research
-
-
[Presentation] Programmed process for synthesis of calcium oxalate crystals in a bufferred glucose solution by irradiation with non-equilibrium atmospheric-pressure plasma2017
Author(s)
Kenji Ishikawa, Naoyuki Kurake, Hiromasa Tanaka, Kae Nakamura, Hiroaki Kajiyama, Fumitaka Kikkawa, Masaaki Mizuno, Yoko Yamanishi, Yuzuru Ikehara, and Masaru Hori
Organizer
iPlasmaNano-VIII July 2-6, 2017. the University of Antwerp, Antwerp, Belgium.
Related Report
Int'l Joint Research
-
-
-
-
-
[Presentation] Fullerenol-addition effects on Plasma-Activated Medium2017
Author(s)
Daiki Kanno, Hiromasa Tanaka, Kenji Ishikawa, Hiroshi Hashizume, Hiroki Kondo, Makoto Sekine, Masaru Hori
Organizer
AEPSE 2017, Jeju International Convention Center, Jeju Island, Republic of Korea, September 11-15, 2017
Related Report
Int'l Joint Research
-
[Presentation] A Novel Controlling Method of differentiation of Cultured Cells on Carbon Nanowalls Scaffold with an Electric Stimulation2017
Author(s)
Tomonori Ichikawa, Suiki Tanaka, Hiroki Kondo, Kenji Ishikawa, Hiroshi Hasizume, Hiromasa Tanaka and Masaru Hori
Organizer
AEPSE 2017, Jeju International Convention Center, Jeju Island, Republic of Korea, September 11-15, 2017
Related Report
Int'l Joint Research
-
[Presentation] Observation of intracellular-molecular changes in plasma-irradiated cells using multiplex coherent anti-Stokes Raman scattering microscopy2017
Author(s)
Takayuki Ohta, Ryo Furuta, Naoyuki Kurake, Kenji Ishikawa, Keigo Takeda, Hiroshi Hashizume, Hiroki Kondo, Masafumi Ito, and Masaru Hori
Organizer
AEPSE 2017, Jeju International Convention Center, Jeju Island, Republic of Korea, September 11-15, 2017
Related Report
Int'l Joint Research
-
[Presentation] Ambient control during preparations of the plasma-activated medium (PAM) for antitumor effects2017
Author(s)
Yugo Hosoi, Kenji Ishikawa, Hiroshi Hashizume, Hiromasa Tanaka, Hiroki Kondo, Makoto Sekine, and Masaru Hori
Organizer
AEPSE 2017, Jeju International Convention Center, Jeju Island, Republic of Korea, September 11-15, 2017
Related Report
Int'l Joint Research
-
-
-
[Presentation] Multiplex Coherent Anti-Stokes Raman Scattering (CARS) Observations of HeLa Cells Cultured in Non-equilibrium Atmospheric Pressure-Plasma-Activated Medium (PAM)2017
Author(s)
Kenji Ishikawa, Ryo Furuta, Keigo Takeda, Takayuki Ohta, Masafumi Ito, Hiroshi Hashizume, Hiromasa Tanaka, Hiroki Kondo, Makoto Sekine, Masaru Hori
Organizer
AVS - 4th International Symposium and Exhibition, October 29-November 03, 2017. Tampa, Florida, USA
Related Report
Int'l Joint Research
-
-
[Presentation] Monitoring of the Plasma Flare at Atmospheric Pressure2017
Author(s)
Hajime Sakakita, Hiromasa Yamada, Tetsuji Shimizu, Masanori Fujiwara, Susumu Kato, Yutaka Fujiwara, Tomonori Hotta, Satoru Kiyama, Jaeho Kim, Keigo Takeda, Kenji Ishikawa, Masaru Hori, Sanae Ikehara, Nobuyuki Shimizu, Hayao Nakanishi, and Yuzuru Ikehara
Organizer
82nd IUVSTA Workshop on Plasma-based Atomic Layer Processes web and 10th EU-Japan Joint Symposium on Plasma Processing, December 4-7, 2017. Okinawa, Japan
Related Report
Int'l Joint Research
-
[Presentation] Morphological Dynamics of Supported Lipid Bilayers in Plasma-activated Liquids Observed by High-Speed Atomic Force Microscopy2017
Author(s)
S. Yamaoka, T. Tonami, H. Hashizume, H. Kondo, K. Ishikawa, H. Tanaka, M. Hori
Organizer
27th annual meeting of MRS-J, Yokohama, Japan, December 5-7, 2017
Related Report
Int'l Joint Research
-
[Presentation] Intracellular responses during incubation in plasma-activated cell culture medium (PAM)2017
Author(s)
Kenji Ishikawa, Ryo Furuta, Naoyuki Kurake, Keigo Takeda, Hiroshi Hashizume, Hiromasa Tanaka, Takayuki Ohta, Masafumi Ito, Hiroki Kondo, Makoto Sekine, and Masaru Hori
Organizer
27th annual meeting of MRS-J, Yokohama, Japan, December 5-7, 2017
Related Report
Int'l Joint Research
-
-
-
[Presentation] Effects of dielectric walls on atmospheric-pressure plasma discharges2017
Author(s)
Kaede Katsuno, Kenji Ishikawa, Takayoshi Tsutsumi, Keigo Takeda, Hiroshi Hashizume, Hiromasa Tanaka, Hiroki Kondo, Makoto Sekine, and Masaru Hori
Organizer
APSPT-10 - 10th Asia-Pacific International Symposium on the Basics and Applications of Plasma Technology, December 15-17, 2017. Taiwan.
Related Report
Int'l Joint Research
-
-
-
-
-
-
-