「リポクオリティ」領域研究の推進

2019 Fiscal Year Annual Research Report

• Project Area: Quality of lipids in biological systems
• Project/Area Number: 15H05897
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: 有田 誠 国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー (80292952)
• Co-Investigator(Kenkyū-buntansha): 有田 正規 国立遺伝学研究所, 情報研究系, 教授 (10356389) ; 瀬藤 光利 浜松医科大学, 国際マスイメージングセンター, センター長 (20302664) ; 反町 典子 国立研究開発法人国立国際医療研究センター, その他部局等, 分子炎症制御プロジェクト長 (30217468) ; 藤本 豊士 順天堂大学, 医学(系)研究科(研究院), 特任教授 (50115929) ; 佐々木 雄彦 東京医科歯科大学, 難治疾患研究所, 教授 (50333365) ; 矢冨 裕 東京大学, 医学部附属病院, 教授 (60200523) ; 横溝 岳彦 順天堂大学, 医学(系)研究科(研究院), 教授 (60302840) ; 岡村 康司 大阪大学, 医学系研究科, 教授 (80201987) ; 杉本 幸彦 熊本大学, 大学院生命科学研究部(薬), 教授 (80243038)
• Project Period (FY): 2015-06-29 – 2020-03-31
• Keywords: 研究支援センター / 領域事務局 / 脂質データベース / 広報活動

Outline of Annual Research Achievements

（１）質量分析センター：ノンターゲット解析（Q-TOF）とターゲット解析(tripleQ)による脂質分析支援を行った。また、ノンターゲット解析から得られた質量分析データの情報処理技術を開発し、約8,000種のリポクオリティ（脂質の構造多様性）を捉えることに成功し、論文発表を行った（有田班）イノシトールリン脂質の位置異性体の個別解析法と集約解析法を領域内外の研究者に提供し、分析支援センターとして運用を行った（佐々木班）（２）脂質イメージングセンター：イメージングデータ解析に機械学習的手法を導入する事で、イメージングデータの半自動化解析法を確立した。また、機械学習を用いてマススペクトルから脳領域を自動分類するアルゴリズムの構築を試み、自動区分を可能にした（瀬藤班）ホスファチジルセリンおよびイノシトールリン脂質可視化解析法を用いた領域内共同研究の成果をまとめた論文２報発表した（藤本班）（３）膜機能解析センター：イノシトールリン脂質PIP2のレベルを短時間で変更する分子ツールVSPの活性を向上させて、これまでの2.5倍の効率で減少できるツールeVSPの改良に成功し論文発表した（岡村班）細胞内スフィンゴミエリンを検出するためのツールとして、蛍光標識EquIIを誘導性に発現するマウスを樹立し、提供できるように準備した（反町班）（４）脂質データベース：脂質117クラスの理論スペクトルおよび，マウス脳における脂質分布の基礎画像情報を公開した（有田班）（５）臨床検体センター：倫理委員会の承認の下、血清、血漿、リポ蛋白、髄液、尿、ヒト手術検体（肝臓、食道、大腸。癌部および正常部）の臨床検体を収集し領域内に提供した（矢冨班）（６）第２回リポクオリティ国際シンポジウム、第5回領域会議（静岡）を開催した（横溝班）領域ニュースレター第5号を発行した（杉本班）

Research Progress Status

令和元年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和元年度が最終年度であるため、記入しない。

Research Products

• [Int'l Joint Research] Rockfeller University/Columbia University/Icahn School of Medicine at Mount Sinai(米国)
  • Country Name: U.S.A.
  • Counterpart Institution: Rockfeller University/Columbia University/Icahn School of Medicine at Mount Sinai
  • # of Other Institutions: 5
• [Int'l Joint Research] University of Cambridge/University of Edinburgh/Babraham Institute(英国)
  • Country Name: UNITED KINGDOM
  • Counterpart Institution: University of Cambridge/University of Edinburgh/Babraham Institute
  • # of Other Institutions: 1
• [Int'l Joint Research] University of Toronto(カナダ)
  • Country Name: CANADA
  • Counterpart Institution: University of Toronto
• [Int'l Joint Research] National University of Singapore(シンガポール)
  • Country Name: SINGAPORE
  • Counterpart Institution: National University of Singapore
• [Int'l Joint Research] Friedrich-Schiller-University Jena(ドイツ)
  • Country Name: GERMANY
  • Counterpart Institution: Friedrich-Schiller-University Jena
• [Int'l Joint Research]
  • # of Other Countries: 4
• [Journal Article] Cysteinyl leukotriene metabolism of human eosinophils in allergic disease (2020)
  • Author(s): Miyata Jun、Fukunaga Koichi、Kawashima Yusuke、Ohara Osamu、Arita Makoto
  • Journal Title: Allergology International Volume: 69 Pages: 28～34
  • DOI: 10.1016/j.alit.2019.06.002
  • Peer Reviewed / Open Access
• [Journal Article] Homeostatic Function of Dermokine in the Skin Barrier and Inflammation (2020)
  • Author(s): Utsunomiya A, Chino T, Utsunomiya N, Luong VH, Tokuriki A, Naganuma T, Arita M, Higashi K, Saito K, Suzuki N, Ohara A, Sugai M, Sugawara K, Tsuruta D, Oyama N, Hasegawa M.
  • Journal Title: Journal of Investigative Dermatology Volume: 140 Pages: 838～849.e9
  • DOI: 10.1016/j.jid.2019.09.011
  • Peer Reviewed
• [Journal Article] A lipidome atlas in MS-DIAL 4. (2020)
  • Author(s): Tsugawa H, Ikeda K, Takahashi M, Satoh A, Mori Y, Uchino H, Okahashi N, Yamada Y, Tada I, Bonini P, Higashi Y, Okazaki Y, Zhou Z, Zhu Z, Koelmel J, Cajka T, Fiehn O, Saito K, Arita M, Arita M.
  • Journal Title: Nature Biotechnology Volume: in press Pages: -
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice (2020)
  • Author(s): Kimura I, Miyamoto J, Ohue-Kitano R, Watanabe K, Yamada T, Onuki M, Aoki R, Isobe Y, Kashihara D, Inoue D, Inaba A, Takamura Y, Taira S, Kumaki S, Watanabe M, Ito M, Nakagawa F, Irie J, Kakuta H, Shinohara M, Iwatsuki K, Tsujimoto G, Ohno H, Arita M, Itoh H, Hase K.
  • Journal Title: Science Volume: 367 Pages: eaaw8429
  • DOI: 10.1126/science.aaw8429
  • Peer Reviewed
• [Journal Article] Synthesis of Phosphatidylcholines Possessing Functionalized Acids at sn-2, and 13C-14N and 13C-31P Couplings in Their 13C NMR Spectra (2020)
  • Author(s): Morita Masao、Saito Shun、Shinohara Riku、Aoyagi Ryohei、Arita Makoto、Kobayashi Yuichi
  • Journal Title: Synlett Volume: 31 Pages: 718-722
  • DOI: 10.1055/s-0039-1691584
  • Peer Reviewed
• [Journal Article] Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL‐expressing plasmacytoid dendritic cells in mice (2020)
  • Author(s): Hirata SI, Nagatake T, Sawane K, Hosomi K, Honda T, Ono S, Ikeda K, Aoyagi R, Adachi J, Abe Y, Isoyama J, Suzuki H, Tomonaga T, Kiyono H, Kabashima K, Arita M, Kunisawa J.
  • Journal Title: Allergy Volume: in press Pages: ー
  • DOI: 10.1111/all.14217
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Prostaglandin E2 and its receptor EP2 trigger signaling that contributes to YAP-mediated cell competition (2020)
  • Author(s): Ishihara E, Nagaoka Y, Okuno T, Ishigami-Yuasa M, Kagechika H, Terai S, Yokomizo T, Sugimoto Y, Fujita Y, Suzuki A, Nishina H.
  • Journal Title: Genes to Cells Volume: 25 Pages: 197-214
  • DOI: 10.1111/gtc.12750
  • Peer Reviewed
• [Journal Article] Induced prostanoid synthesis regulates the balance between Th1- and Th2-producing inflammatory cytokines in the thymus of diet-restricted mice (2020)
  • Author(s): Razali N, Hohjoh H, Inazumi T, Maharjan BD, Nakagawa K, Konishi M, Sugimoto Y, Hasegawa H.
  • Journal Title: Biological and Pharmaceutical Bulletin Volume: 43 Pages: 649-662
  • DOI: 10.1248/bpb.b19-00838
  • Peer Reviewed
• [Journal Article] Effects of the selective EP2 receptor agonist omidenepag on adipocyte differentiation in 3T3-L1 cells (2020)
  • Author(s): Yamamoto Y, Taniguchi T, Inazumi T, Iwamura R, Yoneda K, Odani-Kawabata N, Matsugi T, Sugimoto Y, Shams NK.
  • Journal Title: Journal of Ocular Pharmacology and Therapeutics Volume: 36 Pages: 162-169
  • DOI: 10.1089/jop.2019.0079
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] プロスタグランジンD2レセプターのシグナル伝達 (2020)
  • Author(s): 稲住知明, 杉本幸彦
  • Journal Title: 臨床免疫・アレルギー科（科学評論社） Volume: 73 (13) Pages: 58-63
• [Journal Article] Secreted phospholipase PLA2G2D contributes to metabolic health by mobilizing omega3 polyunsaturated fatty acids in WAT (2020)
  • Author(s): Sato H, Taketomi Y, Miki Y, Murase R, Yamamoto K, Murakami M.
  • Journal Title: Cell Reports Volume: in press Pages: 0
  • Peer Reviewed / Open Access
• [Journal Article] Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress (2020)
  • Author(s): Fujihira, H Masahara-Negishi, Y Akimoto, Y Hirayama, H Lee, H C Story, B A Mueller, W F Jakob, P Clauder-Munster, S Steinmetz, L M Radhakrishnan, S K Kawakami, H Kamada, Y Miyoshi, E Yokomizo, T Suzuki, T
  • Journal Title: Biochim Biophys Acta Mol Basis Dis Volume: 1866 Pages: 165588
  • DOI: 10.1016/j.bbadis.2019.165588
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Loss of autophagy impairs physiological steatosis by accumulation of NCoR1 (2020)
  • Author(s): Takahashi, S S Sou, Y S Saito, T Kuma, A Yabe, T Sugiura, Y Lee, H C Suematsu, M Yokomizo, T Koike, M Terai, S Mizushima, N Waguri, S Komatsu, M
  • Journal Title: Life Sci Alliance Volume: 3 Pages: e201900513
  • DOI: 10.26508/lsa.201900513
  • Peer Reviewed / Open Access
• [Journal Article] n-3 Fatty Acid and Its Metabolite 18-HEPE Ameliorate Retinal Neuronal Cell Dysfunction by Enhancing Muller BDNF in Diabetic Retinopathy (2020)
  • Author(s): Suzumura, A Kaneko, H Funahashi, Y Takayama, K Nagaya, M Ito, S Okuno, T Hirakata, T Nonobe, N Kataoka, K Shimizu, H Namba, R Yamada, K Ye, F Ozawa, Y Yokomizo, T Terasaki, H
  • Journal Title: Diabetes Volume: 69 Pages: 724-735
  • DOI: 10.2337/db19-0550
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The role of propofol hydroxyl group in 5-lipoxygenase recognition (2020)
  • Author(s): Yuki, K Bu, W Eckenhoff, R G Yokomizo, T Okuno, T
  • Journal Title: Biochem Biophys Res Commun Volume: 525 Pages: 909-914
  • DOI: 10.1016/j.bbrc.2020.03.037
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Leukotriene B4 Receptor Type 2 Accelerates the Healing of Intestinal Lesions by Promoting Epithelial Cell Proliferation (2020)
  • Author(s): Matsumoto, Y Matsuya, Y Nagai, K Amagase, K Saeki, K Matsumoto, K Yokomizo, T Kato, S
  • Journal Title: J Pharmacol Exp Ther Volume: 373 Pages: In press
  • DOI: 10.1124/jpet.119.263145
  • Peer Reviewed
• [Journal Article] Aging exacerbates high-fat diet-induced steatohepatitis through alteration in hepatic lipid metabolism in mice (2020)
  • Author(s): Ishizuka, K Kon, K Lee-Okada, H C Arai, K Uchiyama, A Yamashina, S Yokomizo, T Ikejima, K
  • Journal Title: J Gastroenterol Hepatol Volume: - Pages: In press
  • DOI: 10.1111/jgh.15006
  • Peer Reviewed
• [Journal Article] ESCRT machinery mediates selective microautophagy of endoplasmic reticulum. (2020)
  • Author(s): Schafer J, Schessner JP, Tsuju T, Funaya C, Bircham PW, Schaeff K, Ruffini G, Fujimoto T, Schuck S.
  • Journal Title: EMBO J Volume: 39 Pages: e102586
  • DOI: 15252/embj.2019102586
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Possible involvement of PS-PLA1 and lysophosphatidylserine receptor (LPS1) in hepatocellular carcinoma. (2020)
  • Author(s): Uranbileg B, Kurano M, Sato M, Ikeda H, Ishizawa T, Hasegawa K, Kokudo N, Yatomi Y.
  • Journal Title: Sci Rep. Volume: 10 Pages: 2659
  • DOI: 10.1038/s41598-020-59590-3
• [Journal Article] Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism. (2020)
  • Author(s): Nakawatari K, Kurano M, Araki O, Nishikawa M, Shimamoto S, Igarashi K, Aoki J, Murakami M, Yatomi Y.
  • Journal Title: Clin Chim Acta. Volume: 503 Pages: 99-106
  • DOI: 10.1016/j.cca.2020.01.011
• [Journal Article] Protection Against Insulin Resistance by Apolipoprotein M/Sphingosine-1-Phosphate. (2020)
  • Author(s): Kurano M, Tsukamoto K, Shimizu T, Kassai H, Nakao K, Aiba A, Hara M, Yatomi Y.
  • Journal Title: Diabetes Volume: 69 Pages: 867-881
  • DOI: 10.2337/db19-0811
• [Journal Article] Analysis of urinary sphingolipids using liquid chromatography-tandem mass spectrometry in diabetic nephropathy. (2020)
  • Author(s): Morita Y, Kurano M, Sakai E, Nishikawa T, Nishikawa M, Sawabe M, Aoki J, Yatomi Y.
  • Journal Title: J Diabetes Investig Volume: 11 Pages: 441-449
  • DOI: 10.1111/jdi.13154
• [Journal Article] Engineering an enhanced voltage-sensing phosphatase (2020)
  • Author(s): Kawanabe, A, Mizutani N, Polat Onur K,Yonezawa T, Kawai T, Mori M X, Okamura Y.
  • Journal Title: Journal of General Physiology Volume: 152 Pages: e201912491
  • DOI: 10.1085/jgp.201912491
  • Peer Reviewed
• [Journal Article] A common signaling pathway leading to degranulation in mast cells and its regulation by CCR1 ligand. (2020)
  • Author(s): Chang HW, Kanegasaki S, Jin F, Deng Y, You Z, Chang JH, Kim DY, Timilshina M, Kim JR, Lee YJ, Toyama-Sorimachi N, Tsuchiya T.
  • Journal Title: Allergy Volume: in press Pages: 0
  • DOI: 10.1111/all.14186
  • Peer Reviewed
• [Journal Article] Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7. (2020)
  • Author(s): Kikuchi J, Hori M, Iha H, Toyama-Sorimachi N, Hagiwara S, Kuroda Y, Koyama D, Izumi T, Yasui H, Suzuki A, Furukawa Y.
  • Journal Title: Leukemia Volume: 34 Pages: 180-195
  • DOI: 10.1038/s41375-019-0525-6
  • Peer Reviewed
• [Journal Article] リポクオリティの違いを捉えるノンターゲット脂質解析 (2019)
  • Author(s): 内野春希、津川裕司、有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1238-1244
• [Journal Article] アレルギー疾患における好酸球の脂肪酸代謝異常 (2019)
  • Author(s): 宮田純、福永興壱、有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1008-1014
• [Journal Article] ω３脂肪酸クオリティによる疾患制御 (2019)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 967-970
• [Journal Article] 脂質クオリティ研究の基礎と臨床（企画・編集） (2019)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: -
• [Journal Article] 腸内細菌のリポクオリティと生体制御 (2019)
  • Author(s): 安田柊、岡橋伸幸、上田政宏、有田誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 Pages: 393-399
• [Journal Article] 脂肪酸クオリティによる炎症の制御 (2019)
  • Author(s): 有田誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 Pages: 355-361
• [Journal Article] 生体制御にかかわる多彩なリポクオリティ 基礎から病態まで（企画・編集） (2019)
  • Author(s): 有田誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 Pages: -
• [Journal Article] Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis (2019)
  • Author(s): Ishihara Tomoaki、Yoshida Mio、Arita Makoto
  • Journal Title: International Immunology Volume: 31 Pages: 559～567
  • DOI: 10.1093/intimm/dxz001
  • Peer Reviewed / Open Access
• [Journal Article] Lipidomics needs more standardization (2019)
  • Author(s): Lipidomics Standards Initiative Consortium
  • Journal Title: Nature Metabolism Volume: 1 Pages: 745～747
  • DOI: 10.1038/s42255-019-0094-z
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Mass Spectrometry Data Repository Enhances Novel Metabolite Discoveries with Advances in Computational Metabolomics (2019)
  • Author(s): Tsugawa Hiroshi、Satoh Aya、Uchino Haruki、Cajka Tomas、Arita Makoto、Arita Masanori
  • Journal Title: Metabolites Volume: 9 Pages: 119～119
  • DOI: 10.3390/metabo9060119
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dysregulated fatty acid metabolism in nasal polyp-derived eosinophils from patients with chronic rhinosinusitis (2019)
  • Author(s): Miyata Jun、Fukunaga Koichi、Kawashima Yusuke、Watanabe Takashi、Saitoh Akina、Hirosaki Tomomi、Araki Yasutomo、Kikawada Toru、Betsuyaku Tomoko、Ohara Osamu、Arita Makoto
  • Journal Title: Allergy Volume: 74 Pages: 1113～1124
  • DOI: 10.1111/all.13726
  • Peer Reviewed
• [Journal Article] Preferential Incorporation of Administered Eicosapentaenoic Acid Into Thin-Cap Atherosclerotic Plaques (2019)
  • Author(s): Sato Tomohito、Horikawa Makoto、Takei Shiro、Yamazaki Fumiyoshi、Ito Takashi K.、Kondo Takeshi、Sakurai Takanobu、Kahyo Tomoaki、Ikegami Koji、Sato Shumpei、Sato Ryota、Jinno Yasutaka、Kawano Hiroyuki、Naoe Satoko、Arita Makoto、Kashiwagi Yukiyasu、Setou Mitsutoshi
  • Journal Title: Arteriosclerosis, Thrombosis, and Vascular Biology Volume: 39 Pages: 1802～1816
  • DOI: 10.1161/ATVBAHA.119.313093
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids (2019)
  • Author(s): Miyamoto J, Igarashi M, Watanabe K, Karaki S, Mukouyama H, Kishino S, Li X, Ichimura A, Irie J, Sugimoto Y, Mizutani T, Sugawara T, Miki T, Ogawa J, Drucker D, Arita M, Itoh H, Kimura I.
  • Journal Title: Nature Communications Volume: 10 Pages: 4007
  • DOI: 10.1038/s41467-019-11978-0
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Characterization of Lipid Profiles after Dietary Intake of Polyunsaturated Fatty Acids Using Integrated Untargeted and Targeted Lipidomics (2019)
  • Author(s): Naoe Satoko、Tsugawa Hiroshi、Takahashi Mikiko、Ikeda Kazutaka、Arita Makoto
  • Journal Title: Metabolites Volume: 9 Pages: 241～241
  • DOI: 10.3390/metabo9100241
  • Peer Reviewed / Open Access
• [Journal Article] Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice (2019)
  • Author(s): Sawane K, Nagatake T, Hosomi K, Hirata S, Adachi J, Abe Y, Isoyama J, Suzuki H, Matsunaga A, Fukumitsu S, Aida K, Tomonaga T, Arita M, Kunisawa J.
  • Journal Title: Nutrients Volume: 11 Pages: 2868～2868
  • DOI: 10.3390/nu11122868
  • Peer Reviewed / Open Access
• [Journal Article] Lipidomics links oxidized phosphatidylcholines and coronary arteritis in Kawasaki disease (2019)
  • Author(s): Nakashima Y, Sakai Y, Mizuno Y, Furuno K, Hirono K, Takatsuki S, Suzuki H, Onouchi Y, Kobayashi T, Tanabe K, Hamase K, Miyamoto T, Aoyagi R, Arita M, Yamamura K, Tanaka T, Nishio H, Takada H, Ohga S, Hara T.
  • Journal Title: Cardiovascular Research Volume: - Pages: -
  • DOI: 10.1093/cvr/cvz305
  • Peer Reviewed
• [Journal Article] Acyl-CoA synthetase 6 regulates long-chain polyunsaturated fatty acid composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice (2019)
  • Author(s): Shishikura Kyosuke、Kuroha Sayoko、Matsueda Shinnosuke、Iseki Hachiro、Matsui Takeshi、Inoue Azusa、Arita Makoto
  • Journal Title: The FASEB Journal Volume: 33 Pages: 14194～14203
  • DOI: 10.1096/fj.201901074R
  • Peer Reviewed / Open Access
• [Journal Article] Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface (2019)
  • Author(s): Toyoda Y., Morimoto, Suno, Horita, Yamashita, Hirata, Sekiguchi, Yasuda, Shiroishi, Shimizu, Urushibata, Kajiwara, Inazumi, Hotta, Asada, Nakane, Shiimura, Nakagita, Tsuge, Yoshida, Kuribara, Hosoya, Sugimoto, Nomura, Sato, Hirokawa, Kinoshita, Murata, Takayama, Yamamoto, Narumiya, Iwata, Kobayashi, T
  • Journal Title: Nature Chemical Biology Volume: 15 Pages: 18-26
  • DOI: 10.1038/s41589-018-0131-3
  • Peer Reviewed
• [Journal Article] Competition for mitogens regulates spermatogenic stem cell homeostasis in an open niche. (2019)
  • Author(s): Kitadate, Y., Jorg, D.J., Tokue, M., Maruyama, A., Ichikawa, R., Tsuchiya, S., Segi-Nishida, E., Nakagawa, T., Uchida, A., Kimura-Yoshida, C., Mizuno, S., Sugiyama, F., Azami, T., Ema, M., Noda, C., Kobayashi, S., Matsuo, I., Kanai, Y., Nagasawa, T., Sugimoto, Y., Takahashi, S., Simons, B.D., and Yoshida, S.
  • Journal Title: Cell Stem Cell Volume: 24 Pages: 79-92
  • DOI: 10.1016/j.stem.2018.11.013
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Role of cyclooxygenase-2/prostaglandin E2/prostaglandin E receptor 4 signaling in cardiac reprogramming (2019)
  • Author(s): Muraoka N, Nara K, Tamura F, Kojima H, Yamakawa H, Sadahiro T, Miyamoto K, Isomi M, Haginiwa S, Tani H, Kurotsu S, Osakabe R, Torii S, Shimizu S, Okano H, Sugimoto Y, Fukuda K, Ieda M.
  • Journal Title: Nature Communications Volume: 10 Pages: 674
  • DOI: 10.1038/s41467-019-08626-y
  • Peer Reviewed / Open Access
• [Journal Article] Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis (2019)
  • Author(s): Iwasaki R, Tsuge K, Kishimoto K, Hayashi Y, Iwaana T, Hohjoh H, Inazumi T, Kawahara A, Tsuchiya S, Sugimoto Y.
  • Journal Title: Scientific Reports Volume: 9 Pages: 7650
  • DOI: 10.1038/s41598-019-44095-5
  • Peer Reviewed / Open Access
• [Journal Article] Molecular mechanisms underlying prostaglandin E2-exacerbated inflammation and immune diseases (2019)
  • Author(s): Tsuge K, Inazumi T, Shimamoto A, Sugimoto Y.
  • Journal Title: International Immunology Volume: 31 Pages: 597-606
  • DOI: 10.1093/intimm/dxz021
  • Peer Reviewed
• [Journal Article] Cutaneous p38 MAPK 1 activation triggers psoriatic dermatitis (2019)
  • Author(s): Sakurai K, Dainichi T, Garcet S, Tsuchiya S, Yamamoto Y, Kitoh A, Honda T, Nomura T, Egawa G, Otsuka A, Nakajima S, Matsumoto R, Nakano Y, Otsuka M, Iwakura Y, Grinberg-Bleyer Y, Ghosh S, Sugimoto Y, Guttman-Yassky E, Krueger JG, Kabashima K.
  • Journal Title: Journal of Allergy and Clinical Immunology Volume: 144 Pages: 1036-1049
  • DOI: 10.1016/j.jaci.2019.06.019
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Functional hierarchy of uterotonics required for successful parturition in mice (2019)
  • Author(s): Yoshida M, Takayanagi Y, Ichino-Yamashita A, Sato K, Sugimoto Y, Kimura T, Nishimori K.
  • Journal Title: Endocrinology Volume: 160 Pages: 2800-2810
  • DOI: 10.1210/en.2019-00499
  • Peer Reviewed
• [Journal Article] シクロオキシゲナーゼ経路によるリポクオリティ認識 (2019)
  • Author(s): 稲住知明, 杉本幸彦
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 (1) Pages: 1002-1007
• [Journal Article] Novel functions of Phospholipase A2s: Overview (2019)
  • Author(s): Murakami M
  • Journal Title: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Volume: 1864 Pages: 763-765
  • DOI: 10.1016/j.bbalip.2019.02.005
  • Peer Reviewed
• [Journal Article] Group IID, IIE, IIF and III secreted phospholipase A2s (2019)
  • Author(s): Murakami M, Miki Y, Sato H, Murase R, Taketomi Y, Yamamoto K.
  • Journal Title: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Volume: 1864 Pages: 803-818
  • DOI: 10.1016/j.bbalip.2018.08.014
  • Peer Reviewed
• [Journal Article] The role of PNPLA1 in ω-O-acylceramide synthesis and skin barrier function (2019)
  • Author(s): Hirabayashi T, Murakami M, Kihara A.
  • Journal Title: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Volume: 1864 Pages: 869-879
  • DOI: 10.1016/j.bbalip.2018.09.010
  • Peer Reviewed
• [Journal Article] Parkinson’s disease-assocaitaed iPLA2-VIA/PLA2G6 regulates neuronal functions and a-synuclein stability through membrane remodeling (2019)
  • Author(s): Mori A, Hatano T, Inoshita T, Shiba-Fukushima K, Koinuma T, Meng H, Kubo SI, Spratt S, Cui C, Yamashita C, Miki Y, Yamamoto K, Hirabayashi T, Murakami M, Takahashi Y, Shindou H, Nonaka T, Hasegawa M, Okuzumi A, Imai Y, Hattori N.
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 116 Pages: 20689-20699
  • DOI: 10.1073/pnas.1902958116
  • Peer Reviewed / Open Access
• [Journal Article] The orphan nuclear receptor NR4A1 promotes FcεRI-stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis (2019)
  • Author(s): Jin F, Li X, Deng Y, Timilshina M, Huang B, Kim DY, Chang JH, Ichinose H, Baek SH, Murakami M, Lee YJ, Chang HW.
  • Journal Title: Allergy Volume: 74 Pages: 1145-1156
  • DOI: 10.1111/all.13702
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 脂質メディエーターとイムノメタボリズム (2019)
  • Author(s): 佐藤弘泰、村上誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 (2) Pages: 61-71
• [Journal Article] 脂質メディエーターが繋ぐ臓器連関と動的恒常性 (2019)
  • Author(s): 村上誠
  • Journal Title: 実験医学（羊土社） Volume: 37 (7) Pages: 149-155
• [Journal Article] 脂質メディエーターとアレルギー (2019)
  • Author(s): 武富芳隆、村上誠
  • Journal Title: 実験医学（羊土社） Volume: 37 (10) Pages: 88-95
• [Journal Article] ホスホリパーゼA2 による代謝と疾患の制御 (2019)
  • Author(s): 村上誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 (13) Pages: 1024-1028
• [Journal Article] リピドミクスから見えてきた酸化脂肪酸によるマスト細胞の制御機構 (2019)
  • Author(s): 嶋中雄太、村上誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 270 (5) Pages: 401-407
• [Journal Article] Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice (2019)
  • Author(s): Kamata, M Amano, H Ito, Y Fujita, T Otaka, F Hosono, K Kamata, K Takeuchi, Y Yokomizo, T Shimizu, T Majima, M
  • Journal Title: PLoS One Volume: 14 Pages: e0202842
  • DOI: 10.1371/journal.pone.0202842
  • Peer Reviewed / Open Access
• [Journal Article] Papaverine identified as an inhibitor of high mobility group box 1/receptor for advanced glycation end-products interaction suppresses high mobility group box 1-mediated inflammatory responses (2019)
  • Author(s): Tamada, K Nakajima, S Ogawa, N Inada, M Shibasaki, H Sato, A Takasawa, R Yoshimori, A Suzuki, Y Watanabe, N Oyama, T Abe, H Inoue, S Abe, T Yokomizo, T Tanuma, S
  • Journal Title: Biochem Biophys Res Commun Volume: 511 Pages: 665-670
  • DOI: 10.1016/j.bbrc.2019.01.136
  • Peer Reviewed
• [Journal Article] Cyclooxygenase inhibition in mice heightens adaptive- and innate-type responses against inhaled protease allergen and IL-33 (2019)
  • Author(s): Maruyama, N Takai, T Kamijo, S Suchiva, P Ohba, M Takeshige, T Suzuki, M Hara, M Matsuno, K Harada, S Harada, N Nakae, S Sudo, K Okuno, T Yokomizo, T Ogawa, H Okumura, K Ikeda, S
  • Journal Title: Allergy Volume: 74 Pages: 2237-2240
  • DOI: 10.1111/all.13831
  • Peer Reviewed
• [Journal Article] BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses (2019)
  • Author(s): Nagatake, T Hirata, S I Koga, T Kuroda, E Kobari, S Suzuki, H Hosomi, K Matsumoto, N Yanrismet, Y Shimojou, M Morimoto, S Sasaki, F Ishii, K J Yokomizo, T Kunisawa, J
  • Journal Title: Mucosal Immunol Volume: 12 Pages: 1082-1091
  • DOI: 10.1038/s41385-019-0175-z
  • Peer Reviewed
• [Journal Article] An Alternative Pathway to Leukotriene B4 Enantiomers Involving a 1,8-Diol-Forming Reaction of an Algal Oxylipin (2019)
  • Author(s): Jagusch, H Werner, M Okuno, T Yokomizo, T Werz, O Pohnert, G
  • Journal Title: Org Lett Volume: 21 Pages: 4667-4670
  • DOI: 10.1021/acs.orglett.9b01554
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Dietary supplementation of omega-3 fatty acid eicosapentaenoic acid does not ameliorate pruritus in murine models of atopic dermatitis and psoriasis (2019)
  • Author(s): Lee, H C Tominaga, M Yasukawa, K Ohba, M Takahashi, N Honda, K Okuno, T Takamori, K Yokomizo, T
  • Journal Title: J Dermatol Sci Volume: 95 Pages: 130-133
  • DOI: 10.1016/j.jdermsci.2019.07.010
  • Peer Reviewed
• [Journal Article] The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction (2019)
  • Author(s): Koutsogiannaki, S Hou, L Babazada, H Okuno, T Blazon-Brown, N Soriano, S G Yokomizo, T Yuki, K
  • Journal Title: FASEB J Volume: 33 Pages: 12668-12679
  • DOI: 10.1096/fj.201901360R
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system (2019)
  • Author(s): Okuno, T Koutsogiannaki, S Hou, L Bu, W Ohto, U Eckenhoff, R G Yokomizo, T Yuki, K
  • Journal Title: FASEB J Volume: 33 Pages: 14528-14541
  • DOI: 10.1096/fj.201901570R
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation. (2019)
  • Author(s): Zhang, S Kohira, Y Oerita, S Ishimine, M Kobayashi, T Chua, S M B Nakaoka, H Inoue, I Hino, O Yokomizo, T Fukunaga, T H.C., L-O
  • Journal Title: BPB Rep Volume: 2 Pages: 130-133
• [Journal Article] ロイコトリエンB4第1受容体は滲出型加齢黄斑変性症の新規治療標的となる (2019)
  • Author(s): 佐々木文之 横溝岳彦
  • Journal Title: 実験医学 Volume: 37 Pages: 411-414
• [Journal Article] Lysophosphatidylinositol-acyltransferase-1 is involved in cytosolic Ca²⁺ oscillations in macrophages. (2019)
  • Author(s): Takemasu S, Ito M, Morioka S, Nigorikawa K, Kofuji S, Takasuga S, Eguchi S, Nakanishi H, Matsuoka I, Sasaki J, Sasaki T, Hazeki K
  • Journal Title: Genes to cells Volume: 24 Pages: 366-376
  • DOI: 10.1111/gtc.12681
  • Peer Reviewed / Open Access
• [Journal Article] A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites (2019)
  • Author(s): McCormick Barry, Craig Helen E., Chu Julia Y., Carlin Leo M., Canel Marta, Wollweber Florian, Toivakka Matilda, Michael Melina, Astier Anne L., Norton Laura, Lilja Johanna, Felton Jennifer M., Sasaki Takehiko, Ivaska Johanna, Hers Ingeborg, Dransfield Ian, Rossi Adriano G., Vermeren Sonja
  • Journal Title: JOURNAL OF IMMUNOLOGY Volume: 203 Pages: 1579-1588
  • DOI: 10.4049/jimmunol.1900443
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency (2019)
  • Author(s): Nishio Miki, Miyachi Yousuke, Otani Junji, Tane Shoji, Omori Hirofumi, Ueda Fumihito, Togashi Hideru, Sasaki Takehiko, Mak Tak Wah, Nakao Kazuwa, Fujita Yasuyuki, Nishina Hiroshi, Maehama Tomohiko, Suzuki Akira
  • Journal Title: FASEB JOURNAL Volume: 33 Pages: 5548-5560
  • DOI: 10.1096/fj.201802005R
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A Peptide Derived from Phosphoinositide 3-kinase Inhibits Endocytosis and Influenza Virus Infection. (2019)
  • Author(s): Fujioka Y, Satoh AO, Horiuchi K, Fujioka M, Tsutsumi K, Sasaki J, Nepal P, Kashiwagi S, Paudel S, Nishide S, Nanbo A, Sasaki T, Ohba Y
  • Journal Title: Cell structure and function Volume: 44 Pages: 61-74
  • DOI: 10.1247/csf.19001
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression (2019)
  • Author(s): Koizumi Atsushi, Narita Shintaro, Nakanishi Hiroki, Ishikawa Masaki, Eguchi Satoshi, Kimura Hirotaka, Takasuga Shunsuke, Huang Mingguo, Inoue Takamitsu, Sasaki Junko, Yoshioka Toshiaki, Habuchi Tomonori, Sasaki Takehiko
  • Journal Title: SCIENTIFIC REPORTS Volume: 9 Pages: 13257
  • DOI: 10.1038/s41598-019-49744-3
  • Peer Reviewed / Open Access
• [Journal Article] Polarized PtdIns(4,5)P₂ distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility. (2019)
  • Author(s): Kawai T, Miyata H, Nakanishi H, Sakata S, Morioka S, Sasaki J, Watanabe M, Sakimura K, Fujimoto T, Sasaki T, Ikawa M, Okamura Y
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 116 Pages: 26020-26028
  • DOI: 10.1073/pnas.1916867116
  • Peer Reviewed / Open Access
• [Journal Article] 細胞膜での蛋白質-イノシトールリン脂質相互作用へのアシル基の関与 (2019)
  • Author(s): 佐々木雄彦, 山本詠士, 佐々木純子
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1068-1072
• [Journal Article] Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution. (2019)
  • Author(s): Tsuji T, Cheng J, Tatematsu T, Ebata A, Kamikawa H, Fujita A, Gyobu S, Segawa K, Arai H, Taguchi T, Nagata S, Fujimoto T.
  • Journal Title: Proc Natl Acad Sci USA Volume: 116 Pages: 13368-13373
  • DOI: 10.1073/pnas.1822025116
  • Peer Reviewed
• [Journal Article] ROR1-CAVIN3 interaction is required for caveolae-dependent endocytosis and prosurvival signaling in lung adenocarcinoma. (2019)
  • Author(s): Yamaguchi T, Hayashi M, Ida L, Yamamoto M, Lu C, Kajino T, Cheng J, Nakatochi M, Isomura H, Suzuki M, Fujimoto T, Takahashi T.
  • Journal Title: Oncogene Volume: 38 Pages: 5142-5157
  • DOI: 10.1038/s41388-019-0785-7
  • Peer Reviewed
• [Journal Article] Polarized PtdIns(4,5)P2 distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility. (2019)
  • Author(s): Kawai T, Miyata H, Nakanishi H, Sakata S, Morioka S, Sasaki J, Watanabe M, Sakimura K, Fujimoto T, Sasaki T, Ikawa M, Okamura Y.
  • Journal Title: Proc Natl Acad Sci USA Volume: 116 Pages: 26020-26026
  • DOI: 10.1073/pnas.1916867116
  • Peer Reviewed
• [Journal Article] Definition of phosphoinositide distribution in the nanoscale. (2019)
  • Author(s): Tsuji T, Takatori S, Fujimoto T.
  • Journal Title: Curr Op Cell Biol Volume: 57 Pages: 33-39
  • DOI: 10.1016/j.ceb.2018.10.008
  • Peer Reviewed
• [Journal Article] Duo in a mystical realm - nuclear lipid droplets and the inner nuclear membrane. (2019)
  • Author(s): Soltysik K, Ohsaki Y, Fujimoto T.
  • Journal Title: Contact Volume: 2 Pages: 1～11
  • DOI: 10.1177/2515256419896965
  • Peer Reviewed / Open Access
• [Journal Article] 電子顕微鏡を用いた観察 (2019)
  • Author(s): 辻琢磨、藤本豊士
  • Journal Title: 実験医学（別冊）「脂質解析ハンドブック」 Volume: - Pages: 260-267
• [Journal Article] 核内脂肪滴の形成機序と機能の解明 (2019)
  • Author(s): 大崎雄樹、藤本豊士
  • Journal Title: The Lipid Volume: 30 Pages: 346-351
• [Journal Article] Regulation of plasma glycero-lysophospholipid levels by lipoprotein metabolism. (2019)
  • Author(s): Kurano M, Kano K, Hara M, Tsukamoto K, Aoki J, Yatomi Y.
  • Journal Title: Biochem J Volume: 476 Pages: 3565-3581
  • DOI: 10.1042/BCJ20190498
• [Journal Article] Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model. (2019)
  • Author(s): Uranbileg B, Ito N, Kurano M, Saigusa D, Saito R, Uruno A, Kano K, Ikeda H, Yamada Y, Sumitani M, Sekiguchi M, Aoki J, Yatomi Y.
  • Journal Title: Scientific reports Volume: 9 Pages: 16578
  • DOI: 10.1038/s41598-019-52999-5
• [Journal Article] Serum phosphatidylserine-specific phospholipase A1 as a novel biomarker for monitoring systemic lupus erythematosus disease activity. (2019)
  • Author(s): Sawada T, Kurano M, Shirai H, Iwasaki Y, Tahara K, Hayashi H, Igarashi K, Fujio K, Aoki J, Yatomi Y.
  • Journal Title: Int J Rheum Dis Volume: 22 Pages: 2059-2066
  • DOI: 10.1111/1756-185X.13689
• [Journal Article] Redox state of albumin affects its lipid mediator binding characteristics. (2019)
  • Author(s): Kurano M, Yasukawa K, Ikeda H, Aoki J, Yatomi Y.
  • Journal Title: Free Radic Res. Volume: 53 Pages: 892-900
  • DOI: 10.1080/10715762.2019.1641603
• [Journal Article] Evaluation of Lysophospholipid Measurement in Cerebrospinal Fluid Samples using Liquid Chromatography-Tandem Mass Spectrometry. (2019)
  • Author(s): Morita Y, Kurano M, Sakai E, Nishikawa M, Sawabe M, Aoki J, Yatomi Y.
  • Journal Title: Lipids. Volume: 54 Pages: 487-500
  • DOI: 10.1002/lipd.12175
• [Journal Article] Serum GM3(d18:1-16:0) and GM3(d18:1-24:1) levels may be associated with lymphoma: An exploratory study with haematological diseases. (2019)
  • Author(s): Nishikawa M, Kurano M, Nitta T, Kanoh H, Inokuchi JI, Yatomi Y.
  • Journal Title: Sci Rep. Volume: 19 Pages: 6308
  • DOI: 10.1038/s41598-019-42817-3
• [Journal Article] リポクオリティと臨床検査 (2019)
  • Author(s): 蔵野 信，矢冨 裕
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 Pages: 417-423
• [Journal Article] 臨床検査におけるリポクオリティ (2019)
  • Author(s): 蔵野 信，矢冨 裕
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1251-1256
• [Journal Article] Creating a Reliable Mass Spectral-Retention Time Library for All Ion Fragmentation-Based Metabolomics. (2019)
  • Author(s): Tada I, Tsugawa H, Meister I, Zhang P, Shu R, Katsumi R, Wheelock CE, Arita M, Chaleckis R
  • Journal Title: Metabolites Volume: 9 Pages: E251
  • DOI: 10.3390/metabo9110251
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms. (2019)
  • Author(s): Tsugawa H, Nakabayashi R, Mori T, Yamada Y, Takahashi M, Rai A, Sugiyama R, Yamamoto H, Nakaya T, Yamazaki M, Kooke R, Bac-Molenaar JA, Oztolan-Erol N, Keurentjes JJB, Arita M, Saito K
  • Journal Title: Nat Methods Volume: 16 Pages: 295-298
  • DOI: 10.1038/s41592-019-0358-2
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Tenascin C in the Tumor-Nerve Microenvironment Enhances Perineural Invasion and Correlates With Locoregional Recurrence in Pancreatic Ductal Adenocarcinoma. (2019)
  • Author(s): Furuhashi S, Sakaguchi T, Murakami T, Fukushima M, Morita Y, Ikegami K, Kikuchi H, Setou M, Takeuchi H.
  • Journal Title: Pancreas. Volume: 49 Pages: 442-454
  • DOI: 10.1097/MPA.0000000000001506.
  • Peer Reviewed
• [Journal Article] Dietary Intake of Green Nut Oil or DHA Ameliorates DHA Distribution in the Brain of a Mouse Model of Dementia Accompanied by Memory Recovery. (2019)
  • Author(s): Takeyama E, Islam A, Watanabe N, Tsubaki H, Fukushima M, Mamun MA, Sato S, Sato T, Eto F, Yao I, Ito TK, Horikawa M, Setou M.
  • Journal Title: Nutrients Volume: 11 Pages: pii: E2371
  • DOI: 10.3390/nu11102371.
  • Peer Reviewed / Open Access
• [Journal Article] Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter. (2019)
  • Author(s): Nampei M, Horikawa M, Ishizu K, Yamazaki F, Yamada H, Kahyo T, Setou M.
  • Journal Title: Scientific Reports Volume: 9 Pages: 13213
  • DOI: 10.1038/s41598-019-49819-1.
  • Peer Reviewed / Open Access
• [Journal Article] Change in brain plasmalogen composition by exposure to prenatal undernutrition leads to behavioral impairment of rats. (2019)
  • Author(s): Hino K, Kaneko S, Harasawa T, Kimura T, Takei S, Shinohara M, Yamazaki F, Morita SY, Sato S, Kubo Y, Kono T, Setou M, Yoshioka M, Fujino J, Sugihara H, Kojima H, Yamada N, Udagawa J.
  • Journal Title: J Neurosci Volume: 39 Pages: 7689-7702
  • DOI: 10.1523/JNEUROSCI.2721-18.2019.
  • Peer Reviewed / Open Access
• [Journal Article] Preferential Incorporation of Administered Eicosapentaenoic Acid Into Thin-Cap Atherosclerotic Plaques. (2019)
  • Author(s): Sato T, Horikawa M, Takei S, Yamazaki F, Ito TK, Kondo T, Sakurai T, Kahyo T, Ikegami K, Sato S, Sato R, Jinno Y, Kawano H, Naoe S, Arita M, Kashiwagi Y, Setou M.
  • Journal Title: Arterioscler Thromb Vasc Biol Volume: 39 Pages: 1802-1816
  • DOI: 10.1161/ATVBAHA.119.313093.
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of potential anti-aging beverage Pru, a traditional Cuban refreshment, by desorption electrospray innization-mass spectrometry and FTICR tandem mass spectrometry. (2019)
  • Author(s): Mamun MA, Valdes Gonzalez-T, Islam A, Sato T,Sato S, Ito KT, Horikawa M, Yamazaki Fm Alarcon RC, Ido T, Setou M.
  • Journal Title: Journal of Food and Drug Analysis Volume: 27 Pages: 833-840
  • DOI: 10.1016/j.jfda.2019.05.004.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] リポクオリティの可視化 (2019)
  • Author(s): 菊島健児、瀬藤光利
  • Journal Title: The Lipid Volume: 30 Pages: 67-74
• [Journal Article] イメージングMS (2019)
  • Author(s): 佐藤智仁、佐藤駿平、堀川誠、瀬藤光利
  • Journal Title: 実験医学別冊 Volume: - Pages: 268-276
• [Journal Article] 質量顕微鏡法 (2019)
  • Author(s): 荒牧修平、佐藤智仁、堀川誠、華表友暁、瀬藤光利
  • Journal Title: 炎症と免疫 Volume: 27 Pages: 79-82
• [Journal Article] 量子科学技術の生体応用 (2019)
  • Author(s): 荒牧修平、瀬藤光利
  • Journal Title: 脳神経外科 Volume: 17 Pages: 719-731
• [Journal Article] 組織リポクオリティのマスイメージング (2019)
  • Author(s): 櫻井孝信、瀬藤光利
  • Journal Title: 週刊 医学のあゆみ Volume: 269 Pages: 1245-1249
• [Journal Article] 細胞と組織の質量分析イメージング (2019)
  • Author(s): 大山壮歩、堀川誠、櫻井孝信、瀬藤光利
  • Journal Title: 化学工業 Volume: 70 Pages: P1-7
• [Journal Article] Functional analysis of a double-point mutation in the KCNJ2 gene identified in a family with Andersen-Tawil syndrome. (2019)
  • Author(s): Fukumura S, Yamauchi K, Kawanabe A, Yamamoto A, Nakaza M, Kubota T, Kato S, Sasaki R, Okamura Y, Takahashi M.
  • Journal Title: Journal of the Neurological Sciences. Volume: 407 Pages: 0
  • Peer Reviewed
• [Journal Article] Distinct functional properties of two electrogenic isoforms of the SLC34 Na-Pi cotransporter (2019)
  • Author(s): Mizutani N, Okochi Y, Okamura Y.
  • Journal Title: Physiol. Reports Volume: 7 Pages: e14156
  • DOI: 10.14814/phy2.14156
  • Peer Reviewed
• [Journal Article] Real-time functional analysis of Hv1 channel in neutrophils: a new approach from zebrafish model (2019)
  • Author(s): Ratanayotha Adisorn、Kawai Takafumi、Okamura Yasushi
  • Journal Title: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology Volume: 316 Pages: R819～R831
  • DOI: 10.1152/ajpregu.00326.2018
  • Peer Reviewed
• [Journal Article] Molecular mechanisms of coupling to voltage sensors in voltage-evoked cellular signals (2019)
  • Author(s): Okamura Y, Okochi Y.
  • Journal Title: Proc Jpn Acad Ser B Phys Biol Sci. Volume: 95 Pages: 111-135
  • Peer Reviewed
• [Journal Article] Dynamic structural rearrangements and functional regulation of voltage-sensing phosphatase (2019)
  • Author(s): Sakata S .Okamura Y.
  • Journal Title: J. Physiol. Volume: 597 Pages: 29-40
  • Peer Reviewed
• [Journal Article] ホスフォイノシチドによるチャネル・トランスポーターの制御 (2019)
  • Author(s): 岡村康司、水谷夏希、大河内善史
  • Journal Title: 医学のあゆみ Volume: 269 Pages: 1108-1113
• [Journal Article] Cullin‐3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2‐positive breast cancer cells (2019)
  • Author(s): Murakami Akari、Maekawa Masashi、Kawai Katsuhisa、Nakayama Jun、Araki Nobukazu、Semba Kentaro、Taguchi Tomohiko、Kamei Yoshiaki、Takada Yasutsugu、Higashiyama Shigeki
  • Journal Title: Cancer Science Volume: 110 Pages: 650～661
  • DOI: 10.1111/cas.13899
  • Peer Reviewed
• [Journal Article] FAM48A mediates compensatory autophagy induced by proteasome impairment (2019)
  • Author(s): Arata Yoshiyuki、Watanabe Ayaka、Motosugi Ryo、Iemura Shun‐ichiro、Natsume Tohru、Mukai Kojiro、Taguchi Tomohiko、Hirayama Shoshiro、Hamazaki Jun、Murata Shigeo
  • Journal Title: Genes to Cells Volume: 24 Pages: 559～568
  • DOI: 10.1111/gtc.12708
  • Peer Reviewed
• [Journal Article] Innate immunity signalling and membrane trafficking (2019)
  • Author(s): Taguchi Tomohiko、Mukai Kojiro
  • Journal Title: Current Opinion in Cell Biology Volume: 59 Pages: 1～7
  • DOI: 10.1016/j.ceb.2019.02.002
  • Peer Reviewed
• [Journal Article] Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution (2019)
  • Author(s): Tsuji Takuma、Cheng Jinglei、Tatematsu Tsuyako、Ebata Aoi、Kamikawa Hiroki、Fujita Akikazu、Gyobu Sayuri、Segawa Katsumori、Arai Hiroyuki、Taguchi Tomohiko、Nagata Shigekazu、Fujimoto Toyoshi
  • Journal Title: Proceedings of the National Academy of Sciences Volume: 116 Pages: 13368～13373
  • DOI: 10.1073/pnas.1822025116
  • Peer Reviewed
• [Journal Article] SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9. (2019)
  • Author(s): Tanigawa, K., Maekawa, M., Kiyoi, T., Nakayama, J., Kitazawa, R., Kitazawa, S., Semba, K., Taguchi, T., Akita, S., Yoshida, M., Ishimaru, K., Watanabe, Y., and Higashiyama, S.
  • Journal Title: J. Cell. Physiol. Volume: 234 Pages: 17280-17294
  • DOI: 10.1002/jcp.28346
  • Peer Reviewed
• [Journal Article] STING palmitoylation as a therapeutic target. (2019)
  • Author(s): Hansen, A. L., Mukai, K., Schopfer, F. J., Taguchi, T., and Holm, C. K.
  • Journal Title: Cell Mol Immunol Volume: 16 Pages: 236-241
  • DOI: 10.1038/s41423-019-0205-5
  • Peer Reviewed
• [Journal Article] Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis. (2019)
  • Author(s): Kobayashi T, Shimabukuro-Demoto S, Tsutsui H, Toyama-Sorimachi N
  • Journal Title: PLoS Biol. Volume: 17 Pages: e3000530
  • DOI: 10.1371/journal.pbio.3000530
  • Peer Reviewed
• [Journal Article] オルガネラを基軸とした炎症制御機構の理解と疾患治療戦略 (2019)
  • Author(s): 反町典子、Nguyen Tien Dat、小林俊彦
  • Journal Title: 臨床免疫・アレルギー科 Volume: 72 Pages: 313-321
• [Journal Article] リソソーム局在型アミノ酸トランスポーターを標的とした免疫難病治療への挑戦 (2019)
  • Author(s): 反町典子、小林俊彦
  • Journal Title: 医学のあゆみ Volume: 271 Pages: 17-25
• [Presentation] （特別講演）リポクオリティの生物学：炎症や組織恒常性を制御するω３脂肪酸代謝カスケード (2020)
  • Author(s): 有田誠
  • Organizer: 第93回日本薬理学会年会
  • Invited
• [Presentation] Advanced lipidomics to unveil the potential link between lipid metabolism and biological phenotypes (2020)
  • Author(s): Makoto Arita
  • Organizer: RIKEN Glyco-lipidologue Project Symposium 2020
  • Int'l Joint Research / Invited
• [Presentation] リピドミクス新技術による病態・バイオロジー研究 (2020)
  • Author(s): 有田誠
  • Organizer: JKiC研究開発フォーラム
  • Invited
• [Presentation] 多価不飽和脂肪酸としてのω3脂肪酸摂取が雌性生殖と母性行動に与える影響 (2020)
  • Author(s): 橋本美穂, 大窪喜丸, 稲住知明, 杉本聡子, 土屋創健, 杉本幸彦
  • Organizer: 日本薬学会第140年会
• [Presentation] プロスタグランジン受容体による脂質恒常性の調節機構 (2020)
  • Author(s): 稲住知明, 杉本幸彦
  • Organizer: 第93回日本薬理学会年会
  • Invited
• [Presentation] プロスタグランジンI2受容体によるマスト細胞の炎症応答の制御機構 (2020)
  • Author(s): 佐々木諒也, 中尾優子, 村上里穂, 宮本卓馬, 鈴木佑治, 渡辺真由帆, 森本和志, 稲住知明, 土屋創健, 杉本幸彦
  • Organizer: 第36回日本薬学会九州支部大会
• [Presentation] 複数のプロスタグランジン受容体による着床調節機構 (2020)
  • Author(s): 大塚友絵, 稲住知明, 大窪喜丸, 馬驍彦, 杉本聡子, 土屋創健, 廣田泰, 竹尾透, 中潟直己, 杉本幸彦
  • Organizer: 第36回日本薬学会九州支部大会
• [Presentation] リン脂質とエピゲノムを結ぶ新規脂質代謝酵素の解析 (2020)
  • Author(s): 原田沙夜可，佐藤弘康, 武富芳隆，曽我朋義, 相葉俊樹, 大迫誠一郎，村上誠
  • Organizer: 第23回日本栄養病態学会
• [Presentation] リン脂質代謝異常と循環器疾患 (2020)
  • Author(s): 村上誠
  • Organizer: 第80回BLOOD VESSEL CLUB
  • Invited
• [Presentation] ホスホイノシタイドの分子解剖と新しい研究方法論 (2020)
  • Author(s): 佐々木雄彦、山本利義、佐々木純子
  • Organizer: 機能脂質シンポジウム
  • Invited
• [Presentation] 脂質の細胞生物学 ～脂肪滴と脂質ドメインの解析～ (2020)
  • Author(s): 藤本豊士
  • Organizer: The Future of Diabetes Conference 2020
  • Invited
• [Presentation] 肝細胞核内脂肪滴の生理的機能 (2020)
  • Author(s): 藤本豊士
  • Organizer: 第39回アルコール医学生物学研究会
  • Invited
• [Presentation] Promoting trans-omics study through the project of “Imaging Platform” (2020)
  • Author(s): 瀬藤光利
  • Organizer: The 29th Hot Spring Harbor International Symposium
  • Int'l Joint Research / Invited
• [Presentation] The conformational change of the cytoplasmic region of voltage-sensing phosphatase (2020)
  • Author(s): Kawanabe A, Nishizawa M , Nishizawa K ,Narita H, Yonezawa T, Jinno Y, Sakata S, Nakagawa A, Okamura Y.
  • Organizer: the 97th Annual Meeting of the Physiological Society of Japan（第97回日本生理学会大会）
  • Int'l Joint Research
• [Presentation] Regulation of phosphoinositide distribution by voltage-sensing phosphatase in mouse spermatozoa (2020)
  • Author(s): Kawai T, Okamura Y
  • Organizer: the 97th Annual Meeting of the Physiological Society of Japan（第97回日本生理学会大会）
  • Int'l Joint Research
• [Presentation] Analyzing PI(4,5)P2 sensitivity of GABAA receptor by voltage sensing phosphatase (2020)
  • Author(s): Sugimoto S, Kawai T, Okamura Y
  • Organizer: the 97th Annual Meeting of the Physiological Society of Japan（第97回日本生理学会大会）
  • Int'l Joint Research
• [Presentation] Alteration in the coupling between voltage sensor movement and phosphatase activity in voltage-sensing phosphatase with mutation in voltage sensor domani (2020)
  • Author(s): Mizutani N, Okamura Y
  • Organizer: the 97th Annual Meeting of the Physiological Society of Japan（第97回日本生理学会大会）
  • Int'l Joint Research
• [Presentation] Establishment of a method measuring membrane potential in phagosomes (2020)
  • Author(s): Okochi Y, Tsutsui H, Okamura Y.
  • Organizer: the 97th Annual Meeting of the Physiological Society of Japan（第97回日本生理学会大会）
  • Int'l Joint Research
• [Presentation] Biology of LipoQuality: Omega-3 fatty acid cascade that controls inflammation and tissue homeostasis (2019)
  • Author(s): Makoto Arita
  • Organizer: 16th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases
  • Int'l Joint Research / Invited
• [Presentation] Omega-3 fatty acid metabolism that confers anti-inflammation and tissue homeostasis (2019)
  • Author(s): Makoto Arita
  • Organizer: The 7th International Conference on Food Factors (ICoFF2019)
  • Int'l Joint Research / Invited
• [Presentation] （特別講演）リポクオリティが解き明かす生命現象 (2019)
  • Author(s): 有田誠
  • Organizer: 新学術領域研究「化学コミュニケーションのフロンティア」第６回公開シンポジウム
  • Invited
• [Presentation] 病態・バイオロジーを制御する多彩なリポクオリティ (2019)
  • Author(s): 有田誠
  • Organizer: 第30回分子糖尿病学シンポジウム
  • Invited
• [Presentation] 網膜中DHA含有リン脂質の生理学的意義の解明 (2019)
  • Author(s): 黒羽小羊子、堅田侑作、宍倉匡祐、栗原俊英、有田誠
  • Organizer: 第13回メタボロームシンポジウム
• [Presentation] MS-DIAL4.0によるlipidomics standards initiativeに基づく120脂質クラスの包括的解析 (2019)
  • Author(s): 津川裕司、池田和貴、高橋みき子、有田正規、有田誠
  • Organizer: 第13回メタボロームシンポジウム
  • Invited
• [Presentation] Omega-3 fatty acid metabolism that controls inflammation and tissue homeostasis (2019)
  • Author(s): Makoto Arita
  • Organizer: 5th LipidALL International Lipid Symposium
  • Int'l Joint Research / Invited
• [Presentation] Polyunsaturated fatty acid metabolism that controls inflammation and tissue homeostasis (2019)
  • Author(s): Makoto Arita
  • Organizer: 2019 NHRI/IBMS joint International Conference on Inflammation and Disease
  • Int'l Joint Research / Invited
• [Presentation] リポクオリティと脂質栄養 (2019)
  • Author(s): 有田誠
  • Organizer: 日本脂質栄養学会第28回大会
  • Invited
• [Presentation] 炎症や組織恒常性を制御するω３脂肪酸代謝カスケード (2019)
  • Author(s): 有田誠
  • Organizer: 第92回日本生化学会大会
  • Invited
• [Presentation] 好酸球性気道炎症における12/15-リポキシゲナーゼの機能解析 (2019)
  • Author(s): 伊東瑛美、山根剛、宮田純、有田誠
  • Organizer: 第92回日本生化学会大会
• [Presentation] ヒト培養ケラチノサイトにおける脂肪酸代謝系の包括的解析 (2019)
  • Author(s): 中野祐介、永沼達郎、有田誠
  • Organizer: 第92回日本生化学会大会
• [Presentation] アレルギー性結膜炎における12/15-リポキシゲナーゼの機能解析 (2019)
  • Author(s): 高橋優花、小川護、有田誠
  • Organizer: 第92回日本生化学会大会
• [Presentation] 共役リノール酸が脂質代謝に与える影響の包括的解析 (2019)
  • Author(s): 守先由輝子、岡橋伸幸、高藤真由子、池田和貴、有田誠
  • Organizer: 第92回日本生化学会大会
• [Presentation] LC-Q-TOFMSを用いた腸内細菌代謝物のノンターゲットリピドミクス (2019)
  • Author(s): 岡橋伸幸、安田柊、上田政宏、津川裕司、池田和貴、有田誠
  • Organizer: 第44回日本医用マススペクトル学会年会
• [Presentation] アレルギー性接触性皮膚炎の病態形成過程における脂肪酸代謝系の包括的解析 (2019)
  • Author(s): 平野愛美、永沼達郎、有田誠
  • Organizer: 第18回次世代を担う若手ファーマ・バイオフォーラム
• [Presentation] The importance of omega-3/6 fatty acid balance in inflammation and related diseases (2019)
  • Author(s): Makoto Arita
  • Organizer: The 3rd JCS Council Forum on Basic Cardiovascular research
  • Int'l Joint Research / Invited
• [Presentation] アレルギー性接触性皮膚炎の病態制御に関わる脂肪酸代謝系の包括的解析 (2019)
  • Author(s): 野愛美、永沼達郎、有田誠
  • Organizer: 第61回日本脂質生化学会
• [Presentation] Untargeted lipidomics revealed dysregulated ceramide metabolism in the initiation phase of atopic dermatitis (2019)
  • Author(s): Iino Y, Naganuma T, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Omega-3 fatty acid epoxygenase is involved in the regulation of immunological homeostasis in the skin (2019)
  • Author(s): Yoshida M, Ishihara T, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Fat-1 transgenic mice exhibit less fibrosis and inflammatory phenotypes in nonalcoholic fatty liver disease (2019)
  • Author(s): Aoki H, Kang JX, Arita M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Untargeted lipidomics of human vascular endothelial cells under shear stress (2019)
  • Author(s): Hirata T, Ikeda K, Yamamoto K, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Gut microbial metabolite 10-hydroxy-cis-12-octadecaenoic acid (HYA), a novel postbiotics with anti-inflammatory property (2019)
  • Author(s): Oka Y, Yonejima Y, Yasuda S, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Age-associated changes in phospholipid profiles and polyunsaturated fatty acid metabolism in the brain: a lipidomics analysis (2019)
  • Author(s): Sasaki H, Kaneda Y, Rogi T, Shibata H, Aoyagi R, ikeda K, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Dysregulated fatty acid metabolism in nasal polyp-derived eosinophils from patients with chronic rhinosinusitis (2019)
  • Author(s): Miyata J, Fukunaga K, Kawashima Y, Watanabe T, Saitoh A, Hirosaki T, Ohara O, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Eosinophils promote corneal wound healing via the 12/15-lipoxygenase pathway (2019)
  • Author(s): Ogawa M, Isobe Y, Ishihara T, Uchno Y, tsubota K, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Multi-lipidomics for grasping metabolic crosstalk between host and intestinal bacteria (2019)
  • Author(s): Ikeda K, Yasuda S, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] A computational workflow to link untargeted and targeted lipidomics (2019)
  • Author(s): Tsugawa H, Satoh A, Uchino H, Takahashi M, Arita M, Arita M
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Database for understanding the quality of lipids (2019)
  • Author(s): Tsugawa H, Ikeda K, Suwa K, Arita M, Arita M
  • Organizer: 2nd International Conference on LipoQuality
  • Int'l Joint Research / Invited
• [Presentation] Biology of LipoQuality: omega-3 fatty acid cascade that controls inflammation and tissue homeostasis (2019)
  • Author(s): Makoto Arita
  • Organizer: 2nd International Conference on LipoQuality
  • Int'l Joint Research / Invited
• [Presentation] 脂質代謝とアレルギー性炎症 (2019)
  • Author(s): 有田誠
  • Organizer: 第68回日本アレルギー学会学術集会（会長企画JSA-JSIシンポジウム）
  • Invited
• [Presentation] オメガ３脂肪酸代謝による疾患制御 (2019)
  • Author(s): 有田誠
  • Organizer: 第73回日本栄養・食糧学会シンポジウム（油脂・コレステロール研究会共催）
  • Invited
• [Presentation] The importance of LipoQuality in biological systems (2019)
  • Author(s): Makoto Arita
  • Organizer: William Harvey Research Institute Seminar
  • Int'l Joint Research / Invited
• [Presentation] 子宮内膜症におけるプロスタグランジンE受容体の役割 (2019)
  • Author(s): 前田ひかる, 大窪喜丸, 橋本美穂, 稲住知明, 土屋創健, 杉本幸彦
  • Organizer: 第92回日本生化学会大会
• [Presentation] 食事由来ω3脂肪酸含有食が雌性生殖と母性行動に与える影響 (2019)
  • Author(s): 橋本美穂, 大窪喜丸, 稲住知明, 杉本聡子, 土屋創健, 杉本幸彦
  • Organizer: 第92回日本生化学会大会
• [Presentation] 複数の受容体を介したプロスタグランジンの着床制御機構 (2019)
  • Author(s): 稲住知明, 大窪喜丸, 馬驍彦, 大塚友絵, 杉本聡子, 土屋創健, 竹尾透, 中潟直己, 杉本幸彦
  • Organizer: 第92回日本生化学会大会
• [Presentation] 子宮内膜症におけるプロスタグランジンE受容体機能の解析 (2019)
  • Author(s): 前田ひかる, 大窪喜丸, 橋本美穂, 稲住知明, 土屋創健, 杉本幸彦
  • Organizer: 第18回次世代を担う若手ファーマ・バイオフォーラム
• [Presentation] 高ω3脂肪酸含有食が母性行動に与える影響とその分子機構の解析 (2019)
  • Author(s): 橋本美穂, 大窪喜丸, 稲住知明, 杉本聡子, 土屋創健, 杉本幸彦
  • Organizer: 第18回次世代を担う若手ファーマ・バイオフォーラム
• [Presentation] ゼブラフィッシュ腎臓形成におけるプロスタグランジンの役割 (2019)
  • Author(s): 岩穴拓也, 告恭史郎, 岸本幸一朗, 岩崎亮, 稲住知明, 川原敦雄, 土屋創健, 杉本幸彦
  • Organizer: 第61回日本脂質生化学会
• [Presentation] The effect of dietary omega-3 fatty acids on female reproduction and nursing behavior (2019)
  • Author(s): Hashimoto M, Okubo K, Inazumi T, Sugimoto T, Tsuchiya S, Yamashita A, Suhara Y, Arita M, Sugimoto Y.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] The role of multiple prostanoid receptors in embryo implantation and spacing (2019)
  • Author(s): Inazumi T, Okubo K, Xiaoyen Ma, Otsuka T, Hirai Y, Sugimoto T, Tsuchiya S, Takeo T, Nakagata N, Sugimoto Y.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Roles of prostaglandin EP4 receptor axis in adipocytes: relevance of LipoQuality (2019)
  • Author(s): Sugimoto Y.
  • Organizer: 2nd International Conference on Lipoquality
  • Int'l Joint Research / Invited
• [Presentation] アシルセラミド代謝を介した皮膚バリア形成機構 (2019)
  • Author(s): 平林哲也, 武市拓也, 笠原浩二, Alan R. Brash, 村上誠, 秋山真志
  • Organizer: 第42回日本分子生物学会
• [Presentation] PLA2ファミリーによる代謝調節 (2019)
  • Author(s): 村上誠
  • Organizer: 第91回日本生化学会
  • Invited
• [Presentation] ホスホリパーゼA2を起点としたリゾリン脂質経路とアレルギー (2019)
  • Author(s): 武富芳隆, 村上誠
  • Organizer: 第91回日本生化学会
  • Invited
• [Presentation] ヒトとウシの乳汁中脂質プロファイル解析 (2019)
  • Author(s): 長崎祐樹, 川井恵梨佳, 田中充樹, 戸田圭祐, 津嘉山泉, 川上祐生, 高橋吉孝, 岡﨑愉加, 三木寿美, 山本圭, 村上誠, 山本登志子
  • Organizer: 第91回日本生化学会
• [Presentation] 乾癬におけるXIIA型ホスホリパーゼA2（sPLA2-XIIA）の役割 (2019)
  • Author(s): 望月茅可, 高宮里奈, 杉本奈央, 三木寿美, 武富芳隆, 村上誠
  • Organizer: 第91回日本生化学会
• [Presentation] 皮膚における新規細胞質型ホスホリパーゼA2（cPLA2δ, cPLA2ε）の機能解析 (2019)
  • Author(s): 梁陸伊韻, 三木寿美, 平林哲也, 平家圭奈子, 小林哲幸, 山本圭, 武富芳隆, 高宮里奈, 村上誠
  • Organizer: 第91回日本生化学会
• [Presentation] 脂肪細胞のベージュ化に関わる２種類のThermogenic sPLA2sの同定 (2019)
  • Author(s): 佐藤弘泰, 武富芳隆, 三木寿美, 村上誠
  • Organizer: 第91回日本生化学会
• [Presentation] リゾホスホリパーゼPNPLA7はメチオニン欠乏により誘導されエピゲノム制御に関わる (2019)
  • Author(s): 原田沙夜可，武富芳隆，川口舞，平林哲也，大迫誠一郎，村上誠
  • Organizer: フォーラム2019衛生薬学・環境トキシコロジー
• [Presentation] PLA2分子ファミリーによるリポクオリティ調節と疾患制御 (2019)
  • Author(s): 村上誠
  • Organizer: 第17回レドックス・ライフイノベーションシンポジウム
  • Invited
• [Presentation] Phospholipid metabolism and lipid mediators in health and diseases (2019)
  • Author(s): Murakami M.
  • Organizer: Asia Pacific Society for Biology and Medical Sciences (APSBMS) 2019 Annual Meeting
  • Int'l Joint Research / Invited
• [Presentation] sPLA2ファミリーと代謝疾患 (2019)
  • Author(s): 村上誠
  • Organizer: 第40回日本炎症・再生医学会
  • Invited
• [Presentation] PLA2と炎症・再生 (2019)
  • Author(s): 村上誠
  • Organizer: 第40回日本炎症・再生医学会
  • Invited
• [Presentation] PLA2分子群と皮膚疾患 (2019)
  • Author(s): 村上誠
  • Organizer: 第61回日本脂質生化学会
  • Invited
• [Presentation] PNPLA8、PNPLA7を介した内因性コリン産生経路は肝臓のメチル基供給に寄与する (2019)
  • Author(s): 川口舞, 平林哲也, 笠原浩二, 村上誠
  • Organizer: 第61回日本脂質生化学会
• [Presentation] IIF型分泌性ホスホリパーゼA2/リゾプラズマローゲン経路は表皮肥厚性疾患の新規創薬ターゲットである (2019)
  • Author(s): 山本圭, 箱井春香, 三木寿美, 村上誠
  • Organizer: 第61回日本脂質生化学会
• [Presentation] PLA2G3-driven lysophospholipid pathway protects against allergic asthma (2019)
  • Author(s): Takagi K, Taketomi Y, Tanoue A, Matsuyama T, Sakaue K, Machida K, Murakami M, Inoue H.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] The lysophospholipase PNPLA7 is induced by methionine depletion and is linked to epigenetic regulation (2019)
  • Author(s): Harada S, Taketomi Y, Kawaguchi M, Hirabayashi T, Murakami M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Phosphatidylcholine catabolism mediated by PNPLA8 and PNPLA7 has an important role in supplying methyl groups in the liver (2019)
  • Author(s): Kawaguchi M, Hirabayashi T, Murakami M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Group IVE phospholipase A2 (cPLA2ε) mobilizes the non-canonical lipid mediator N-acylethanolamine in mouse skin (2019)
  • Author(s): Liang L, Heike K, Kobayashi T, Hirabayashi T, Miki Y, Yamamoto K, Taketomi Y, Murakami M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Group IIA phospholipase A2 regulates gut microbiome (2019)
  • Author(s): Miki Y, Taketomi Y, Yamamoto K, Hosomi K, Kunisawa J, Siddabasave GB, Ikeda K, Arita M, Murakami M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Distinct Roles of phospholipase A2s in colitis and colonic cancer (2019)
  • Author(s): Murase R, Taketomi Y, Miki Y, Yamamoto K, Murakami M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Group IID phospholipase A2 promotes browning of white adipose tissue and limits diet-induced obesity (2019)
  • Author(s): Sato H, Taketomi Y, Miki Y, Yamamoto K, Makoto Murakami
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Group III phospholipase A2 promotes atherosclerosis (2019)
  • Author(s): Taketomi Y, Miyazaki T, Sato H, Miki Y, Murakami M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Exosome could be the source of lipid mediator in cancer platform (2019)
  • Author(s): Kudou K, Miki Y, Higuchi H, Yamamoto K, Murakami M, Kotani A.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Inhibition of arachidonate 5-lipoxygenase and improvement in psoriasis by red rice proanthocyanidin (2019)
  • Author(s): Toda K, Nagasaki Y, Tsukayama I, Tamenobu A, Konoike Y, Ganeko N, Ito H, Kawakami Y, Takahashi Y, Miki Y, Yamamoto K, Murakami M, Suzuki-Yamamoto T.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] Group IIF phospholipase A2/lysoplasmalogen axis is a novel drug target for epidermal-hyperplasic disease (2019)
  • Author(s): Yamamoto K, Hakoi H, Miki Y, Murakami M.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL)
  • Int'l Joint Research
• [Presentation] LipoQuality regulation by the phospholipase A2 family (2019)
  • Author(s): Murakami M.
  • Organizer: 2nd International Conference on Lipoquality
  • Int'l Joint Research / Invited
• [Presentation] 脂質とアレルギー疾患 (2019)
  • Author(s): 村上誠
  • Organizer: 第68回日本アレルギー学会
  • Invited
• [Presentation] Identification of a novel metabolic pathway that links phospholipids to methionine metabolism (2019)
  • Author(s): 川口舞, 平林哲也, 村上誠
  • Organizer: 第19回東京大学生命科学シンポジウム
• [Presentation] The roles of omega-3 and omega-6 fatty acids in ocular diseases (2019)
  • Author(s): Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids, Invited lecture
  • Int'l Joint Research / Invited
• [Presentation] COX-2, cPGES, and SLCO2A1-dependent ammonic PGE2 accumulation during human labor (2019)
  • Author(s): Okuno, T Takahashi, N Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] Lysophosphatidic Acid Mediates Acute Inflammatory Pain in Mice Models (2019)
  • Author(s): Hashimoto, Y Ito, N Saigusa, D Okuno, T Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] The role of leukotriene A4 hydrolase in metabolism (2019)
  • Author(s): Uzawa, H Saeki, K Koga, T Okuno, T Miyatsuka, T Watada, H Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] β2 integrins affect eicosanoid production and breast cancer growth (2019)
  • Author(s): Koutsogiannaki, S Wang, W Bautista, J Okuno, T Yokomizo, T Yuki, K
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] BLT1 promotes intestinal IgA production against oral vaccine by mediating commensal bacteria-dependent innate immune signals for plasma cell proliferation (2019)
  • Author(s): Nagatake, T Hirata, S I Koga, T Kuroda, E Kobari, S Suzuki, H Hosomi, K Matsumoto, N Yanrismet, Y Shimojou, M Marimoto, S Sasaki, F Ishii, K J Yokomizo, T Kunisawa, J
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] Protective roles of leukotriene B4 receptor type 2 in pneumolysin-induced epithelial injury (2019)
  • Author(s): Chi, Y Saeki, K Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] Spatiotemporal regulation of novel DC subsets by LTB4-BLT1 signaling (2019)
  • Author(s): Koga, T Sasaki, F Saeki, K Okuno, T Nakao, M Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] Deficiency of BLT1, the high-affinity receptor for LTB4, alleviates allergic conjunctivitis in mice (2019)
  • Author(s): Hirakata, T Lee, C H Yasukawa, K Adachi, K Saeki, K Okuno, T Murakami, A Matsuda, A Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] Regulatory mechanism of expression of polyunsaturated fatty acids-related genes (2019)
  • Author(s): Ri, K Lee, C H Yokomizo, T
  • Organizer: 60th ICBL, International Conference on the Bioscience of Lipids
  • Int'l Joint Research
• [Presentation] 脂肪酸不飽和化酵素FADS2欠損マウスにおける脂質プロファイル異常 (2019)
  • Author(s): 李賢哲、李慶賢、平形寿彬、横溝岳彦
  • Organizer: 第61回日本脂質生化学会
• [Presentation] 高度不飽和脂肪酸欠乏時における脂質関連遺伝子発現の変動 (2019)
  • Author(s): 李慶賢、李賢哲、横溝岳彦
  • Organizer: 第61回日本脂質生化学会
• [Presentation] ヒト陣痛における羊水中PGE2蓄積は細胞質型PGE合成酵素依存的である (2019)
  • Author(s): 奥野利明、高橋七瀬、横溝岳彦
  • Organizer: 第61回日本脂質生化学会
• [Presentation] リン脂質におけるイオンモビリティ値である衝突断面積の解析 (2019)
  • Author(s): 上野紀子、中西広樹、李賢哲、横溝岳彦
  • Organizer: 第61回日本脂質生化学会
• [Presentation] ロイコトリエンB4産生経路およびロイコトリエンB4受容体BLT1は滲出型加齢黄斑変性症の新規治療標的となる (2019)
  • Author(s): 佐々木文之、古賀友紹、横溝岳彦
  • Organizer: 第40回日本炎症・再生学会 (シンポジウム)
  • Invited
• [Presentation] 代謝におけるロイコトリエンA4水解酵素の役割の解析 (2019)
  • Author(s): 鵜澤博嗣、古賀友紹、佐伯和子、奥野利明、綿田裕孝、横溝岳彦
  • Organizer: 第92回日本生化学会
• [Presentation] セリン加水分解酵素ABHD4の生化学的解析および機能解析 (2019)
  • Author(s): 李賢哲、Cravatt, B F、横溝岳彦
  • Organizer: 第92回日本生化学会
• [Presentation] Lysophosphatidic acid mediates formalin-induced inflammatory pain in mice (2019)
  • Author(s): Hoshino, Y Ito, N Saigusa, D Okuno, T Yokomizo, T
  • Organizer: 49th Annual meeting of the society for Neuroscience
  • Int'l Joint Research
• [Presentation] The roles of leukotriene B4 receptor in macrophage and dendritic cell (2019)
  • Author(s): Yokomizo, T
  • Organizer: 16th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases, Symposium
  • Int'l Joint Research / Invited
• [Presentation] Identification of a novel mutation in SLCO2A1 gene, encoding a prostaglandin transporter (2019)
  • Author(s): Okuno, T Jimbo, K Ohgaki, R Kanai, Y Shimizu, T Yokomizo, T
  • Organizer: 16th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases, Progress in Lipid Research-Young Investigator Award Lecture
  • Int'l Joint Research
• [Presentation] The effects of dietary supplementation of an omega-3 fatty acid eicosapentaenoic acid on pruritus in murine atopic dermatitis and psoriasis models (2019)
  • Author(s): Yasukawa, K Lee, C H Tominaga, M Ohba, M Takahashi, N Honda, K Okuno, T Takamori, K Yokomizo, T
  • Organizer: 16th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
  • Int'l Joint Research
• [Presentation] Age-related enhancement of cellular stresses and lipotoxicity exacerbates dietary steatohepatitis in mice (2019)
  • Author(s): Ishizuka, K Kon, K Lee, H C Arai, K Uchiyama, A Fukada, H Yamashina, S Yokomizo, T Ikejima, A Ikejima, K
  • Organizer: AASLD The Liver Meeting 2019
  • Int'l Joint Research
• [Presentation] Dietary glycine prevents metabolic steatohepatitis in diabetic KK-Ay mice through remodeling of hepatic lipid profile (2019)
  • Author(s): Tada, M Uchiyama, A Lee, H C Arai, K Fukuhara, K Kon, K Yamashina, S Ikejima, K
  • Organizer: AASLD The Liver Meeting 2019
  • Int'l Joint Research
• [Presentation] Lipoquality of phosphoinositides (2019)
  • Author(s): Takehiko Sasaki, Eiji Yamamoto, Toshiyoshi Yamamoto, Junko Sasaki
  • Organizer: 2nd International Conference on LipoQuality
  • Int'l Joint Research / Invited
• [Presentation] 卵巣の性維持とイノシトールリン脂質 (2019)
  • Author(s): 佐々木純子、佐々木雄彦
  • Organizer: 第18 回生命科学研究会
• [Presentation] リンパ腫細胞株ホスホイノシタイド脂肪酸組成の多変量解析を用いた抗がん剤感受性予測について (2019)
  • Author(s): 山本利義、阿部史人、田川博之、佐々木雄彦.
  • Organizer: 第18 回生命科学研究会
• [Presentation] 良い脂質、悪い脂質、普通の脂質 (2019)
  • Author(s): 佐々木雄彦
  • Organizer: 文の京最先端生命科学講座第24 回
  • Invited
• [Presentation] イノシトールリン脂質のアシル基と生理機能 (2019)
  • Author(s): 佐々木純子, 山本詠士, 長谷川純矢, 佐々木雄彦
  • Organizer: 第92回日本生化学会大会
  • Invited
• [Presentation] アルツハイマー病遺伝学的リスク因子INPP5D の病態関与に関する研究 (2019)
  • Author(s): 高鳥翔, 井口明優, 木村新伍, 佐々木純子, 佐々木雄彦, 高井俊行, 斉藤貴志, 西道隆臣, 富田泰輔
  • Organizer: 第92回日本生化学会大会
  • Invited
• [Presentation] 腎癌におけるイノシトールリン脂質発現プロファイル (2019)
  • Author(s): 成田伸太郎, 中西広樹, 松田芳教, 小泉淳, 江口賢史, 高須賀俊輔, 黄明国, 井上高光, 佐々木純子,
  • Organizer: 日本癌学会総会
• [Presentation] アルツハイマー病リスク遺伝子INPP5D がTREM2 シグナル伝達において果たす役割の解明 (2019)
  • Author(s): 井口明優, 高鳥翔, 木村新伍, 佐々木純子, 斉藤貴志, 西道隆臣, 高井俊行, 佐々木雄彦, 富田泰輔
  • Organizer: Dementia Japan
• [Presentation] Molecular dissection of phosphoinositides (2019)
  • Author(s): Junko Sasaki, Eiji Yamamoto, Toshiyoshi Yamamoto, Takehiko Sasaki
  • Organizer: The 14th International Symposium of the Institute Network for Biomedical Sciences 2019
  • Int'l Joint Research / Invited
• [Presentation] Phosphoinositide Fingerprinting in Cancer (2019)
  • Author(s): Takehiko Sasaki, Eiji Yamamoto, Toshiyoshi Yamamoto, Junko Sasaki
  • Organizer: TOHOKU FORUM for CREATIVITY Thematic Program“Cancer from Biology to Acceptance”International Symposium 2
  • Int'l Joint Research / Invited
• [Presentation] Nuclear lipid droplets (2019)
  • Author(s): Toyoshi Fujimoto
  • Organizer: EuroCellNet Workshop “Nuclear architecture, lipids, and phase separation”
  • Int'l Joint Research / Invited
• [Presentation] Lipid droplet formation in the nucleus (2019)
  • Author(s): Toyoshi Fujimoto
  • Organizer: University of Zurich Institute of Molecular Life Science,Lecture series in molecular life sciences,2019,2019,1,1
  • Int'l Joint Research / Invited
• [Presentation] Lipid droplets in the hepatocyte nucleus (2019)
  • Author(s): Toyoshi Fujimoto
  • Organizer: 17th Chinese Biophysics Conference
  • Int'l Joint Research / Invited
• [Presentation] Phospholipid landscape in cellular membranes (2019)
  • Author(s): Toyoshi Fujimoto
  • Organizer: 60th ICBL LipoQuality Satellite Symposium
  • Int'l Joint Research / Invited
• [Presentation] 脂肪滴の謎を探る (2019)
  • Author(s): 藤本豊士
  • Organizer: 認定NPO法人 綜合画像研究支援 創立十五周年記念シンポジウム
  • Invited
• [Presentation] 脂肪滴と膜脂質の解析 (2019)
  • Author(s): 藤本豊士
  • Organizer: 生化学若い研究者の会 近畿支部主催 初夏のセミナー
  • Invited
• [Presentation] 血中グリセロリゾリン脂質産生酵素はバセドウ病で上昇する． (2019)
  • Author(s): 蔵野 信，西川 真子，五十嵐 浩二，村上 正巳，矢冨 裕
  • Organizer: 第116回 日本内科学会総会・講演会
• [Presentation] スフィンゴシン1-リン酸/アポ蛋白Mによる抗インスリン抵抗性作用の解明． (2019)
  • Author(s): 蔵野 信，塚本 和久，原 眞純，矢冨 裕
  • Organizer: 第62回 日本糖尿病学会年次学術集会
• [Presentation] 髄液中リゾホスファチジン酸，リゾホスファチジルコリンは客観的疼痛マーカーである． (2019)
  • Author(s): 蔵野 信，住谷 昌彦，坂井 英里，可野 邦行，青木 淳賢，矢冨 裕
  • Organizer: 第44回 日本医用マススペクトル学会年会
• [Presentation] ヒトサンプルを用いた生理活性脂質測定系によるヒト疾患病態の解明と臨床検査への応用． (2019)
  • Author(s): 蔵野 信，森田 賢史，坂井 英里，Uranbileg B，青木 淳賢，矢冨 裕．
  • Organizer: 第66回 日本臨床検査医学会学術集会．
  • Invited
• [Presentation] Involvement of LPA and its precursor LPC, in spinal cord stenosis: A study using a rat CEC model. (2019)
  • Author(s): Uranbileg, B., Ito, N., Kurano, M., Ikeda, H., and Yatomi, Y.
  • Organizer: 第59回 日本臨床化学会年次学術集会．
• [Presentation] Possible involvement of PS-PLA1 and lysophosphatidylserine receptor (LPS1) in hepatocellular carcinoma. (2019)
  • Author(s): Uranbileg, B., Kurano, M., Sato, M., Ikeda, H., and Yatomi, Y.
  • Organizer: 第66回 日本臨床検査医学会学術集会．
• [Presentation] Apolipoprotein M and sphingosine 1-phosphate prevents the progression of diabetic nephropathy. (2019)
  • Author(s): Kurano, M. and Yatomi, Y.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Involvement of Lysiphosphatidic acid and Autotaxin in neuropathic pain caused by spinal cord stenosis in rat models. (2019)
  • Author(s): Uranbileg, B., Ito, N., Kurano, M., Saigusa, D., Kano, K., Ikeda, H., Yamada, Y., Sekiguchi, M., Aoki, J., Sumitani, M., and Yatomi, Y.
  • Organizer: 60th International Conference on the Bioscience of Lipids (ICBL2019)
  • Int'l Joint Research
• [Presentation] Lysophospholipids as disease biomarkers. 2nd International Conference on Lipoquality. (2019)
  • Author(s): Yatomi, Y. and Kurano, M.
  • Organizer: 2nd International Conference on LipoQuality
  • Int'l Joint Research / Invited
• [Presentation] Involvement of dysregulation of apolipoprotein M, a sphingosine 1-phosphate carrier, in human diseases. (2019)
  • Author(s): Yatomi, Y. and Kurano, M.
  • Organizer: 16th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases
  • Int'l Joint Research / Invited
• [Presentation] Cheminformatics for Predicting Structures from Mass Spectra (2019)
  • Author(s): Masanori Arita
  • Organizer: 1st Annual Conference of Chinese Society of Metabolomics
  • Int'l Joint Research / Invited
• [Presentation] Data sharing and the power of omics integration (2019)
  • Author(s): Masanori Arita
  • Organizer: 6th Global Forum of Leaders for Agricultural Science and Technology?
  • Int'l Joint Research / Invited
• [Presentation] 生体試料を光で判別するための分析シート (2019)
  • Author(s): 瀬藤光利
  • Organizer: ライフサイエンス 新技術説明会
  • Invited
• [Presentation] 顕微質量分析法の分子解剖学への展開と新分野の開拓 (2019)
  • Author(s): 瀬藤光利
  • Organizer: 日本学術振興会マイクロビームアナリシス141委員会 受賞記念講演
  • Invited
• [Presentation] 質量顕微鏡について (2019)
  • Author(s): 瀬藤光利
  • Organizer: 第15回日本ファブリー病フォーラム
  • Invited
• [Presentation] Mass Spectrometry based imaging of LipoQuality (2019)
  • Author(s): 瀬藤光利
  • Organizer: 60th International Conference on the Bioscience of Lipids
  • Int'l Joint Research / Invited
• [Presentation] 質量分析技術の老化研究への応用 (2019)
  • Author(s): 瀬藤光利
  • Organizer: 第19回日本抗加齢学会総会
• [Presentation] 脂質のマスイメージング (2019)
  • Author(s): 瀬藤光利
  • Organizer: 第67回質量分析総合討論会
• [Presentation] 自然免疫分子STINGの活性化を支えるゴルジ体脂質ドメイン (2019)
  • Author(s): 田口友彦、向井康治朗
  • Organizer: 第61回日本脂質生化学会
  • Invited
• [Presentation] 自然免疫分子STINGの活性を厳密に制御する細胞内物質輸送 (2019)
  • Author(s): 田口友彦、向井康治朗
  • Organizer: 2019年生理学研究所研究会
  • Invited
• [Presentation] 自然免疫分子STINGの活性化分子機構 (2019)
  • Author(s): 向井康治朗、仁木隆裕、新井洋由、田口友彦
  • Organizer: 第92回生化学会大会
  • Invited
• [Presentation] Indication of the involvement of a Golgi sphingomyelin-enriched domain in the inntate immunity signalling (2019)
  • Author(s): Tomohiko Taguchi
  • Organizer: GLYCO25th
  • Int'l Joint Research / Invited
• [Presentation] Cis-interaction between NK receptor and MHC class I mediates bulk phagocytosis in macrophages (2019)
  • Author(s): 反町典子、田口友彦
  • Organizer: 第４８回日本免疫学会学術集会
• [Presentation] SLC15A3 inhibits autophagy in macrophage and dendritic cells (2019)
  • Author(s): Dat Nguyen-Tien、小林俊彦、反町典子
  • Organizer: 第４８回日本免疫学会学術集会
• [Presentation] Sphingolipid microdomains in innate immune cells. (2019)
  • Author(s): Noriko Toyama-Sorimachi.
  • Organizer: 2nd International Conference on LipoQuality 2019 (60th ICBL Satellite Symposium）
  • Int'l Joint Research / Invited
• [Presentation] エンドリソソームに依存した炎症制御ー疾患横断的治療標的の探索に向けてー (2019)
  • Author(s): 反町典子
  • Organizer: 免疫サマースクール2019 in 愛媛
  • Invited
• [Presentation] Coupling Mechanisms of VSD Mutants of CI-VSP (2019)
  • Author(s): Mizutani N, Okamura Y
  • Organizer: 64th Biophysical Society Annual Meeting
  • Int'l Joint Research
• [Presentation] マウス精子に存在する電位依存性ホスファターゼの機能 (2019)
  • Author(s): 河合喬文、岡村康司
  • Organizer: 第112回近畿生理学談話会
• [Presentation] Regulation of ion channels by distribution of phospholipids in mouse sperm (2019)
  • Author(s): Okamura Y
  • Organizer: Ion Channel Modulation Symposium
  • Int'l Joint Research / Invited
• [Presentation] Improvement of voltage-sensing phosphatase as a molecular tool for phosphoinositide depletion in living cells (2019)
  • Author(s): Kawanabe A, Mizutani N, Yonezawa T, Okamura Y
  • Organizer: The 57th Annual Meeting of the Biophysical Society of Japan
  • Int'l Joint Research
• [Presentation] Evolutional insight into the orign of clustering of voltage-gated sodium channels (2019)
  • Author(s): Okamura Y, Jinno Y, Hashimoto M, Nishino J, Sasakura Y, Nishino A, Kawai T
  • Organizer: NEURO2019（第42回日本神経科学大会、第62回日本神経化学会大会）
• [Presentation] Functional role of VSP in mouse sperm through its regulation of phosphoinositide distribution (2019)
  • Author(s): Okamura Y
  • Organizer: The 7th International Ion Channel Conference (IICC-7)
  • Int'l Joint Research / Invited
• [Presentation] Analysis of membrane potential of phagosome in phagocytes (2019)
  • Author(s): Okochi Y, Tsutsui H, Okamura Y.
  • Organizer: 60th International Conference on the Bioscience of Lipids（ICBL2019）
  • Int'l Joint Research
• [Presentation] The hydrophobic protein-membrane interface maintains an activity of a phosphoinositide phosphatase (2019)
  • Author(s): Kawanabe A, Hashimoto M, Yonezawa T, Jinno Y, Okamura Y.
  • Organizer: 60th International Conference on the Bioscience of Lipids（ICBL2019）
  • Int'l Joint Research
• [Presentation] Function of voltage-sensing phosphatase in mouse sperm (2019)
  • Author(s): Kawai T,Miyata H, Nakanishi H, Sakata S, Okochi Y, Watanabe M, Fujimoto T, Sakimura K, Sasaki T, Ikawa M, Okamura Y
  • Organizer: 60th International Conference on the Bioscience of Lipids（ICBL2019）
  • Int'l Joint Research
• [Presentation] Voltage sensing phosphatase: crossroad of electrical signal and lipid signal (2019)
  • Author(s): Okamura Y, Kawai T, Kawanabe A
  • Organizer: 60th International Conference on the Bioscience of Lipids（ICBL2019）
  • Int'l Joint Research
• [Presentation] Molecular mechanisms and physiological functions of voltage-sensing phosphatase, VSP (2019)
  • Author(s): Okamura Y
  • Organizer: Seminar on Vollum Institute, Oregon Health ＆ Science University
  • Int'l Joint Research / Invited
• [Book] 脂質解析ハンドブック (2019)
  • Author(s): 佐々木雄彦
  • Total Pages: 8
  • Publisher: 羊土社
  • ISBN: 978-4-7581-2241-2
• [Book] The Lipid (2019)
  • Author(s): 田口友彦
  • Total Pages: 9
  • Publisher: メディカルレビュー社
  • ISBN: 978-4-7792-2321-1
• [Book] 生化学 (2019)
  • Author(s): 西野 敦雄、岡村 康司
  • Total Pages: 8
  • Publisher: 日本生化学学会
• [Remarks] リポクオリティ領域HP
  • URL: https://sites.google.com/site/lipoqualityjpn/
• [Remarks] 理研IMSメタボローム研究チームHP
  • URL: http://www.ims.riken.jp/labo/53/index_j.html
• [Remarks] 慶應義塾大学薬学部代謝生理化学講座HP
  • URL: http://keio-pha-pcm.jp
• [Remarks] 横浜市大大学院生命医科学研究科代謝エピゲノム科学HP
  • URL: http://www.tsurumi.yokohama-cu.ac.jp/lab/cme.html
• [Remarks] 順天堂大学医学部生化学第一講座HP
  • URL: http://plaza.umin.ac.jp/j_bio/
• [Patent(Industrial Property Rights)] 慢性特発性蕁麻疹の重症度マーカー、及びその使用 (2019)
  • Inventor(s): 村上誠
  • Industrial Property Rights Holder: 日本大学・東京大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2019-101289
• [Funded Workshop] 2nd International Conference on LipoQuality (2019)
• [Funded Workshop] 60th International Conference on the Bioscience of Lipids (ICBL2019) (2019)