Hybrid Catalysis for Enabling Molecular Synthesis on Demand

2022 Fiscal Year Final Research Report

• Project Area: Hybrid Catalysis for Enabling Molecular Synthesis on Demand
• Project/Area Number: 17H06441
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: The University of Tokyo
• Principal Investigator: Kanai Motomu 東京大学, 大学院薬学系研究科(薬学部), 教授 (20243264)
• Project Period (FY): 2017-06-30 – 2022-03-31
• Keywords: 触媒 / 有機合成化学 / ハイブリッド触媒 / 均一系触媒 / 固体触媒 / 高分子化学 / 天然物合成 / ドミノ触媒

Outline of Final Research Achievements

Many of the substances indispensable for the enrichment of human health and culture are composed of organic molecules. Synthetic organic chemistry is the only way to create and stably supply these substances. Although synthetic organic chemistry has made progress, it is still difficult to supply the necessary organic molecules in the required quantities with the current capabilities. To solve this problem, we have created hybrid catalyst systems that utilize the function of multiple catalysts in a concerted manner, and have pioneered extremely efficient organic synthetic reactions that, if realized, would have a great impact but were not possible in the past. As a result, we have realized a molecular synthesis-on-demand that rapidly assembles value-added, complex organic molecules from simple, readily available raw materials according to demand.

Free Research Field

触媒化学

Academic Significance and Societal Importance of the Research Achievements

個別に発展してきた有機触媒、金属錯体触媒、不斉触媒、光触媒、固体触媒といった触媒化学分野に加えて、物理化学、理論科学、高分子化学、天然物合成化学に携わる多分野の研究者を結集し、ハイブリット触媒系の創製に焦点を絞った研究を複合的かつ強力に推進した点で学術的意義がある。これにより本領域は、今後発展が大きく期待される有機合成化学分野の研究を、国内外を問わず先導し、新たな潮流を創り出してきた。また、単純で入手容易な有機分子から高付加価値の有機分子を、環境負荷を低減しながら地球規模で供給する触媒システムの創製を実現してきたところに社会的意義がある。