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2022 Fiscal Year Final Research Report

Singularity biology

Administrative Group

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Project AreaSingularity biology
Project/Area Number 18H05408
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionOsaka University

Principal Investigator

Nagai Takeharu  大阪大学, 産業科学研究所, 教授 (20311350)

Project Period (FY) 2018-06-29 – 2023-03-31
Keywordsシンギュラリティ / 特異点 / 生物現象 / AMATERAS
Outline of Final Research Achievements

Research: We developed 1. Information analysis technology for extracting feature value that identify singularity cells from images, 2. Technology for extracting necessary information from big data, 3. Data platform that integrates big data obtained by the planning team and public recruitment team, 4. Comprehensive cell sorting technology , and 5. 6. Explored imaging modalities,
Development of AMATERAS: We promoted usage by releasing promotion video, and excavated the singularity phenomenon by strengthening development and research through collaboration within this area and developed AMATERAS ver3.
Management of the research area: The results of the project were widely disseminated by holding meetings and symposium, and publishing newsletters, etc.

Free Research Field

生物物理学

Academic Significance and Societal Importance of the Research Achievements

ビッグバンのように「無から有が創出される特異点」や、人工知能がヒトの知能を凌駕する技術的特異点はシンギュラリティと呼ばれていて、生命現象においてもシンギュラリティが絡む現象が広く存在するが、その作用機序はほとんど明らかにされていなかった。そこで、シンギュラリティが絡む現象を理解するため、希少な細胞やイベントを見逃さない、超広視野と高解像度、高速と長時間撮影を両立したイメージング装置と得られるビッグ画像を定量解析する手法を開発し、シンギュラリティとなりうる細胞が生成される作用機序とその生物学的な役割を解明する新しい学術の開拓を目指した。

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Published: 2024-01-30  

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