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2009 Fiscal Year Self-evaluation Report

Cell Proliferation Control

Administrative Group

  • PDF
Project AreaCell Proliferation Control
Project/Area Number 19057004
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionTokyo Institute of Technology

Principal Investigator

KISHIMOTO Takeo  Tokyo Institute of Technology, 大学院・生命理工学研究科, 教授 (00124222)

Project Period (FY) 2007 – 2012
Keywords細胞周期 / 細胞増殖 / 細胞分化 / チェックポイント / サイクリン / CDK / CDKインヒビター / 多細胞体制
Research Abstract

特定領域研究「細胞周期フロンティア-増殖と分化相関」(略称・細胞増殖制御)では、細胞の増殖と分化のバランスの分子基盤について、細胞周期制御を鍵とした統合的な理解を得ることを目指しており、それによって細胞周期研究のフロンティアを創成しようとしている。こうした領域の目的を達成するために、本総括班は、有機的な研究連携の場を構築して組織的かつ機動的に研究を推進・支援するとともに、領域の活動を領域の内外に積極的に広報し、さらには評価・助言担当者から意見を得て領域の運営に反映させていくことを目指している。

  • Research Products

    (10 results)

All 2010 2009 2008 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (3 results) Book (2 results) Remarks (1 results)

  • [Journal Article] 14-3-3γmediates Cdc25A proteolysis to induce S and G2 arrest after DNA damage.2010

    • Author(s)
      Kasahara, H., Goto, H., Enomoto, M., Tomono, Y., Kiyono, T., Inagaki, M.
    • Journal Title

      EMBO J. (in press)

    • Peer Reviewed
  • [Journal Article] Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transition in starfish eggs.2010

    • Author(s)
      Tachibana, K., Mori, M., Matsuhira, T., Karino, T., Inagaki, T., Nagayama, A., Nishiyama, A., Hara, M., Kishimoto, T.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 107

      Pages: 5006-5011

    • Peer Reviewed
  • [Journal Article] Emi2 inhibition of the APC/C absolutely requires Emi2 binding via the C-terminal RL tail.2010

    • Author(s)
      Ohe, M., Kawamura, Y., Ueno, H., Inoue, D., Kanemori, Y., Senoo, C., Isoda, M., Nakajo, N., Sagata, N.
    • Journal Title

      Mol. Biol. Cell 21

      Pages: 905-913

    • Peer Reviewed
  • [Journal Article] A Jumonji (Jarid2) Protein Complex Represses cyclin D1 Expression by Methylation of Histone H3-K9.2009

    • Author(s)
      Shirato, H., Ogawa, S., Nakajima, K., Inagawa, M., Kojima, M., Tachibana, M., Shinkai, Y., Takeuchi, T.
    • Journal Title

      J. Biol. Chem. 284

      Pages: 733-739

    • Peer Reviewed
  • [Presentation] Dual lock for cell cycle arrest in unfertilized mature starfish eggs.2009

    • Author(s)
      Kishimoto, T.
    • Organizer
      Les Treilles Conference "Meiotic Division in Oocytes"
    • Place of Presentation
      Les Treilles, France
    • Year and Date
      20090622-20090627
  • [Presentation] Roles of Jumonji in transcriptional control and development.2008

    • Author(s)
      Takeuchi, T.
    • Organizer
      第21回内藤コンファレンス
    • Place of Presentation
      北杜市
    • Year and Date
      20080624-20080627
  • [Presentation] Revisit to MPF.2008

    • Author(s)
      Kishimoto, T.
    • Organizer
      Jacques Monod Conference "The cell cycle and genomic instability"
    • Place of Presentation
      Roscoff, France
    • Year and Date
      20080426-20080430
  • [Book] Oogenesis: The Universal Process(ed. Verlhac, M.H., Cytostatic arrest: Post-ovulation arrest until fertilization in metazoan oocytes.)2010

    • Author(s)
      Nishiyama, T., Tachibana, K., Kishimoto, T.
    • Total Pages
      357-384
    • Publisher
      Wiley-Blackwell
  • [Book] 細胞工学(1月号)特集「細胞周期研究の新たなステージ」2009

    • Author(s)
      岸本健雄
    • Total Pages
      1-58
    • Publisher
      秀潤社
  • [Remarks] 特定領域「細胞増殖制御」

    • URL

      http://www.cellprolif.bio.titech.ac.jp/

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

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