Systems molecular ethology to understand the operating principle of the nervous system

2010 Fiscal Year Self-evaluation Report

• Project Area: Systems molecular ethology to understand the operating principle of the nervous system
• Project/Area Number: 20115001
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: The University of Tokyo
• Principal Investigator: IINO Yuichi The University of Tokyo, 大学院・理学系研究科, 教授 (40192471)
• Project Period (FY): 2008-11-13 – 2014-03-31
• Keywords: 行動素過程 / 神経回路 / 学習 / モデル生物 / 行動学 / 行動遺伝学

Research Abstract

動物行動を構成する基本的素過程の分子レベルからの理解は重要であるが、従来の研究では実験系ないしは研究手法の制限により十分な解明がなされてこなかった。そこで本研究領域では線虫やショウジョウバエなどのモデル生物を中心として哺乳類に至るまでの各種生物の研究者に加え、化学、数理科学や工学の研究者を集結させて新学問領域の形成を行う。計画研究に加え、公募研究の研究者の参加が領域発展には重要である。総括班はこのような多数の研究者が主体的に進める研究を支援し、研究者間の研究協力や情報交換を促進し、領域全体の研究の発展を円滑に推進するための、研究領域の中枢として組織する極めて重要な機能体である。

Research Products

• [Journal Article] Population density-dependent olfactory plasticity is mediated by pheromonal and neuropeptide signaling in Caenorhabditis elegans. (2010)
  • Author(s): Yamada, K., Hirotsu, T., Matsukil, M., Butcher, R.A., Tomioka, M., Ishihara, T., Clardy, J., Kunitomo, H., Iino, Y.
  • Journal Title: Science 329 Pages: 1647-1650
  • Peer Reviewed
• [Journal Article] Recognition of pre- and postsynaptic neurons via nephrin/NEPH1 homologs is a basis for the formation of the Drosophila retinotopic map. (2010)
  • Author(s): Sugie, A., Umetsu, D., Yasugi, T., Fischbach, K.-F., Tabata, T.
  • Journal Title: Development 137(19) Pages: 3303-3313
  • Peer Reviewed
• [Journal Article] Long-tail behavior in locomotion of Caenorhabditis elegans. (2010)
  • Author(s): Ohkubo J, Yoshida K, Iino Y, Masuda N.
  • Journal Title: J Theor Biol. 267 Pages: 213-222
  • Peer Reviewed
• [Journal Article] The Drosophila CAM Klingon is required for long-term memory formation and is regulated by Notch. (2009)
  • Author(s): Matsuno, M., Horiuchi, J., Tully, T., Saitoe, M.
  • Journal Title: Proc Natl Acad Sci USA 106 Pages: 310-315
  • Peer Reviewed
• [Journal Article] Functional role of a specialized class of spinal commissural inhibitory neurons during fast escapes in zebrafish. (2009)
  • Author(s): Satou, C., Kimura, Y., Kohashi, T., Horikawa, K., Takeda, H., Oda, Y., Higashijima, S.
  • Journal Title: J.Neuroscience 29 Pages: 6780-6793
  • Peer Reviewed
• [Presentation] Development and function of V2 neurons in zebrafish spinal cord (2010)
  • Author(s): Higashijima, S.
  • Organizer: 2nd Joint Meeting of the French and Japanese Societies for Developmental Biology
  • Place of Presentation: Paris Invited talk
  • Year and Date: 20100500
• [Presentation] Pheromonal interactions modulate behavioral plasticity in C.elegans (2010)
  • Author(s): Iino, Y.
  • Organizer: East Asia C.elegans Meeting
  • Place of Presentation: Tokyo Invited talk
  • Year and Date: 2010-07-14
• [Presentation] Simultaneous presentation of two attractants modifies taxis behavior in C.elegans. (2010)
  • Author(s): Shingai, R.
  • Organizer: 第87回日本生理学会大会シンポジウム(Studies on behaviors of relatively simple model animals)
  • Place of Presentation: Morioka Invited talk
  • Year and Date: 2010-05-21
• [Presentation] Imaging molecular processes in living cells (2009)
  • Author(s): Sato M.
  • Organizer: Janelia Farm Conferecne on Fluorescent Proteins and Biological Sensors II
  • Place of Presentation: Virginia, USA Invited talk
  • Year and Date: 2009-11-03
• [Presentation] Spatio-temporal regulation of DER and Notch signaling pathways organizes the proneural wave progression in medulla neuroblast development. (2009)
  • Author(s): Tabata, T.
  • Organizer: Neurobiology of Drosophila
  • Place of Presentation: Cold Spring Harbor Laboratory Invited talk
  • Year and Date: 2009-09-29
• [Remarks] 領域ホームページ
  • URL: http://www.molecular-ethology.jp/
• [Remarks] C.エレガンスシナプス結合データベースおよびオンラインツール(岩崎唯史、新貝鉚蔵)
  • URL: http://ims.dse.ibaraki.ac.jp/ccep/