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2023 Fiscal Year Final Research Report

Management of PLAMP research

Administrative Group

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Project AreaEstablishment of PLAMP as a new concept to determine self and nonself for obligatory intracellular pathogens
Project/Area Number 20H05770
Research Category

Grant-in-Aid for Transformative Research Areas (B)

Allocation TypeSingle-year Grants
Review Section Transformative Research Areas, Section (III)
Research InstitutionOsaka University

Principal Investigator

YAMAMOTO MASAHIRO  大阪大学, 微生物病研究所, 教授 (00444521)

Co-Investigator(Kenkyū-buntansha) 橋口 隆生  京都大学, 医生物学研究所, 教授 (50632098)
新崎 恒平  東京薬科大学, 生命科学部, 准教授 (70609990)
Project Period (FY) 2020-10-02 – 2023-03-31
KeywordsPLAMP / 新しいパターン / 生きた病原体
Outline of Final Research Achievements

Here is the English translation of the provided text:
The Pathogen PLAMP Management Team held an annual online team meeting to ensure smooth research progress for each Pathogen PLAMP subgroup, with activities guided by advice from a famous professor of infection and Immunity, an advisor. Additionally, as an international conference, the team organized the Awaji Infection and Immunity Forum in 2022, hosting a symposium centered on PLAMP. This event brought together numerous microbiology and immunology researchers both online and at the Research Institute for Microbial Diseases, Osaka University, to disseminate the concept of PLAMP. In this way, the Pathogen PLAMP research was promoted by the Management Team.

Free Research Field

感染免疫学

Academic Significance and Societal Importance of the Research Achievements

病原体PLAMP研究が採択された時に丁度起こっていた新型コロナウイルスによって、人々は行動制限を設けられ、マスク生活を強いられ、それにより社会・経済活動に大きな傷跡を残した。病原体PLAMP研究は、宿主細胞と相互作用するウイルス・細菌・寄生虫に共通する新しい概念である。PLAMPの同定によって、PLAMPを標的とした新しい病原体制御技術や治療戦略ができることに、医学的意義のみならず、大きな社会的意義がある。また宿主と病原体の相互作用の研究は、いつ出現するかわからない次のパンデミックに備えるために、総括班が一丸となって国際学会を開催された社会的意義も大きい。

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Published: 2025-01-30  

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