2016 Fiscal Year Annual Research Report
Plasma Medical Science Innovation
Project Area | Plasma medical innovation |
Project/Area Number |
24108001
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Research Institution | Nagoya University |
Principal Investigator |
堀 勝 名古屋大学, 工学研究科, 教授 (80242824)
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Co-Investigator(Kenkyū-buntansha) |
田中 昭代 九州大学, 医学研究院, 講師 (10136484)
池原 譲 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 (10311440)
水野 彰 豊橋技術科学大学, 工学(系)研究科(研究院), シニア研究員 (20144199)
吉川 史隆 名古屋大学, 医学系研究科, 教授 (40224985)
節原 裕一 大阪大学, 接合科学研究所, 教授 (80236108)
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Project Period (FY) |
2012-06-28 – 2017-03-31
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Keywords | プラズマ / プラズマ医療科学 / 医工連携 / 止血 / 遺伝子導入 / 再生医療 / がん治療 / 安全安心 |
Outline of Annual Research Achievements |
平成28年度は本領域研究の活性化に加え、領域内外での連携促進と成果発信を目的に、以下を実施した。1) プラズマ、生物、医療及び当該融合領域における世界トップレベルの研究に関する一般向けアウトリーチとして、市民公開講座「のぞいてみよう! プラズマと生物と医療の不思議な世界」を、本領域と新学術領域「脳タンパク質老化」とで共同開催(H28.8.10)し、本領域の魅力と展望を紹介した。2) 本領域内での連携強化を念頭に、キックオフミーティングでは本領域内で有機的に融合したグループに分かれて終日討論し、更にグループ発表を領域全体で行い、本年度での終了に向けた活動方針を明確にした。(H28.4.25-26)。3) グループ融合の活動成果を踏まえ、第5回「プラズマ医療科学の創成」研究会を合宿形式で開催(H28.12.23)し、本領域での研究の総括に向けて活発に議論した。また九州大学春日キャンパスQuest施設の見学会を開催(H28.12.24)し、本領域にも関わる研究グループと活発に討論した。4) プラズマ科学プラットフォーム開所記念講演会(H28.4.26)を開催し、900名を超える聴衆に「プラズマ医療科学」の活動を紹介した。5) 本領域主催の国際会議「International Conference on Plasma Medical Science Innovation」を開催(H29.2.26)し、海外からの多数の研究者を交えて、プラズマ医療科学の進展と展望を活発に討論した。6) 一般市民向けアウトリーチとして、「サイエンスの扉」及び「サイエンスカフェ」を月一度、開催し、本領域の成果を紹介した。7) 領域内拠点でのセミナー、本領域における医工連携と相互理解を図るためのプラズマ医療に関する用語のメルマガ配信等、本領域内外への相互連携の強化に資する方策と情報発信を精力的に行った。
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Research Progress Status |
28年度が最終年度であるため、記入しない。
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Strategy for Future Research Activity |
28年度が最終年度であるため、記入しない。
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Remarks |
2016年度受賞一覧 http://horilab.nuee.nagoya-u.ac.jp/index.php?id=687
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Research Products
(75 results)
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[Journal Article] Intraperitoneal Administration of Plasma-Activated Medium: Proposal of a Novel Treatment Option for Peritoneal Metastasis From Gastric Cancer2017
Author(s)
Shigeomi Takeda, Suguru Yamada, Norifumi Hattori, Kae Nakamura, Hiromasa Tanaka, Hiroaki Kajiyama, Mitsuro Kanda, Daisuke Kobayashi, Chie Tanaka, Tsutomu Fujii, Michitaka Fujiwara, Masaaki Mizuno, Masaru Hori, Yasuhiro Kodera
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Journal Title
Annals of Surgical Oncology
Volume: 24
Pages: 1188-1194
DOI
Peer Reviewed
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[Journal Article] Red Blood Cell Coagulation Induced by Low-temperature Plasma Treatment2016
Author(s)
K. Miyamoto, S. Ikehara, H. Takei, Y. Akimoto, H. Sakakita, K. Ishikawa, M. Ueda, J. Ikeda, M. Yamagishi, J. Kim, T. Yamaguchi, H. Nakanishi, T. Shimizu, N. Shimizu, M. Hori, and Y. Ikehara
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Journal Title
Arch. Biochem. Biophys.
Volume: 605
Pages: 95-101
DOI
Peer Reviewed
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[Journal Article] Cell survival of glioblastoma grown in medium containing hydrogen peroxide and/or nitrite, or in plasma-activated medium2016
Author(s)
N. Kurake, H. Tanaka, K. Ishikawa, T. Kondo, M. Sekine, K. Nakamura, H. Kajiyama, F. Kikkawa, M. Mizuno, and M. Hori
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Journal Title
Arch. Biochem. Biophys.
Volume: 605
Pages: 102-108
DOI
Peer Reviewed / Acknowledgement Compliant
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[Presentation] プラズマ活性培養液(PAM)処理グリオーマのメタボロミクス解析2017
Author(s)
倉家 尚之, 田中 宏昌, 石川 健治, 橋爪 博司 中村 香江, 梶山 広明, 吉川 史隆, 水野 正明, 竹田 圭吾, 近藤 博基, 関根 誠, 堀 勝
Organizer
第64回応用物理学会春季学術講演会
Place of Presentation
パシフィコ横浜
Year and Date
2017-03-14 – 2017-03-17
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[Presentation] A mechanism on generations of H2O2 and NO2― in plasma activated medium2017
Author(s)
Naoyuki Kurake, Hiromasa Tanaka, Kenji Ishikawa, Kae Nakamura, Hiroaki Kajiyama, Fumiaki Kikkawa, Takashi Kondo, Masaaki Mizuno, Keigo Takeda, Hiroki Kondo, Makoto Sekine and Masaru Hori
Organizer
International Conference on Plasma Medical Science Innovation (ICPMSI) 2017
Place of Presentation
Nagoya University
Year and Date
2017-02-27 – 2017-02-28
Int'l Joint Research
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[Presentation] 高速原子間力顕微鏡を用いたプラズマ活性培養液内の 活性酸素窒素種による支持脂質二重膜変化の解析2017
Author(s)
戸波卓也, 倉家尚之, 橋爪博司, 近藤博基, 石川健治, 竹田圭吾, 田中宏昌, 関根誠, 伊藤昌文, 手老龍吾, 堀 勝
Organizer
第34回 プラズマプロセシング研究会/第29回 プラズマ材料科学シンポジウム
Place of Presentation
北海道大学・学術交流会館
Year and Date
2017-01-16 – 2017-01-18
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[Presentation] Plasma-activated Medium (PAM) and Metabolic Analysis of Glioblastoma2016
Author(s)
Kenji ISHIKAWA, Naoyuki KURAKE, Hiroshi HASHIZUME, Hiromasa TANAKA, Keigo TAKEDA, Hiroki KONDO, Makoto SEKINE, Takashi KONDO, Shoko OHNUMA, Masashi KATO, Kae NAKAMURA, Hiroaki AJIYAMA, Fumitaka KIKKAWA, Masaaki MIZUNO, Shinya TOYOKUNI, and Masaru HORI
Organizer
The 26th annual meeting of MRS-J
Place of Presentation
Yokohama, Japan
Year and Date
2016-12-19 – 2016-12-22
Int'l Joint Research / Invited
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[Presentation] Plasma-activated medium and Cancer2016
Author(s)
H. Tanaka, M. Mizuno, K. Ishikawa, K. Takeda, H. Kondo, H. Hashizume, K. Nakamura, H. Kajiyama, H. Kano, Y. Okazaki, S. Toyokuni, S. Maruyama, F. Kikkawa, and M. Hori
Organizer
6th International Conference on Plasma Medicine (ICPM-6)
Place of Presentation
Slovak University of Technology, Slovakia
Year and Date
2016-09-04 – 2016-09-09
Int'l Joint Research / Invited
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[Presentation] Particulates generation in the plasma activated medium (PAM)2016
Author(s)
N.Kurake, H.Tanaka, K.Ishikawa, H.hashizume, K.Nakamura, H.Kajiyama, F.Kikkawa, T.Kondo, M.Mizuno, K.Takeda, H.Kondo, M.Sekine, M.Hori
Organizer
6th International Conference on Plasma Medicine
Place of Presentation
Bratislava, Slovakia
Year and Date
2016-09-04 – 2016-09-09
Int'l Joint Research
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[Presentation] Comparison of Inflammation after hemostasis with non-thermal plasma or thermal coagulation: A histological and nuclear medical evaluation2016
Author(s)
M. Ueda, D.Yamagami, A.Morioka, K.Watanabe, K.Sano, A.Mori, H.Kimra, H.Saji, H.Sakakita, Y.Ikehara, K.Ishikawa, M.Hori, S.Enomoto
Organizer
6th International Conference on Plasma Medicine
Place of Presentation
Bratislava, Slovakia
Year and Date
2016-09-04 – 2016-09-09
Int'l Joint Research
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[Presentation] Mechanisum of blood coagulation induced by plasma treatment in addition to the acceleration of the natural blood coagulation process2016
Author(s)
Y.Ikehara, S.Ikehara, Y,.Akimoto, H.sakakita, K.Ishikawa, M.Ueda, J.Ikeda, J.Kim, Y.Yamaguchi, H.Nakanishi, T.Shimizu, N.Shimizu, M. Hori
Organizer
6th International Conference on Plasma Medicine
Place of Presentation
Bratislava, Slovakia
Year and Date
2016-09-04 – 2016-09-09
Int'l Joint Research
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[Presentation] Metabolic profiles on glioblastoma (U251SP) modified in plasma-activated medium (PAM) cultivation2016
Author(s)
K.Ishikawa, N.Kurake, H.Tanaka, H.Hashizume, K.Takeda, K.Nakamura, H.Kajiyama, H.Kondo, M.Sekine, M.Kato, M.Mizuno, F.Kikkawa, M.Hori
Organizer
6th International Conference on Plasma Medicine
Place of Presentation
Bratislava, Slovakia
Year and Date
2016-09-04 – 2016-09-09
Int'l Joint Research
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[Presentation] Latent Chemistry in Plasma activated medium (PAM)2016
Author(s)
Kenji Ishikawa, Naoyuki Kurake, Hiromasa Tanaka, Hiroko Mizuno, Hiroshi Hashizume, Keigo Takeda, Hiroki Kondo, Makoto Sekine, Takashi Kondo, Shoko Ohnuma, Masashi Kato, Kae Nakamura, Hiroaki Kajiyama, Fumitaka Kikkawa, Masaaki Mizuno, Masaru Hori
Organizer
20th International Vacuum congress (IVC-20)
Place of Presentation
Busan, Korea
Year and Date
2016-08-21 – 2016-08-26
Int'l Joint Research
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[Presentation] PLASMA TREATMENT INDUCES BLOOD CLOT FORMATION; PROTEIN AGGREGATION AND HEMOLYSIS2016
Author(s)
Y. Ikehara, S. Ikehara, T. Yamaguchi, Y. Akimoto, H. Sakakita, J. Kim, K. Ishikawa, M. Hori, H. Nakanishi, N. Shimizu
Organizer
43rd IEEE International Conference on Plasma Science
Place of Presentation
Banff, Alberta, Canada
Year and Date
2016-06-19 – 2016-06-23
Int'l Joint Research / Invited
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[Presentation] Increase in Galectin expression In Healing Wounded Skin Treated with Low-Temperature Plasma: Comparison with Treatment By Electronical Coagulation2016
Author(s)
Y. Akimoto, S. Ikehara, Y. Yamaguchi, J. Kim, H. Kawakami, N. Shimizu, M. Hori, H. Sakakita, Y. Ikehara
Organizer
43rd IEEE International Conference on Plasma Science
Place of Presentation
Banff, Alberta, Canada
Year and Date
2016-06-19 – 2016-06-23
Int'l Joint Research
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[Presentation] Impact of Synergism of nitrate and hydrogen Peroxide on cell survivals in plasma-activated-medium(PAM)2016
Author(s)
N. Kurake, H. Tanaka, K. Ishikawa, K.Nakamura, H. Kajiyama, F. Kikkawa, T. Kondo, M. Mizuno, H. Kondo, M. Sekine, M. Hori
Organizer
43rd IEEE International Conference on Plasma Science
Place of Presentation
Banff, Alberta, Canada
Year and Date
2016-06-19 – 2016-06-23
Int'l Joint Research
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[Presentation] INTRACELLULAR MOLECULAR MECHANISMS OF CANCER CELL DEATH USING PLASMA-ACTIVATED MEDIUM2016
Author(s)
Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Keigo Takeda, Hiroshi Hashizume, Kae Nakamura, Fumi Utsumi, Hiroaki Kajiyama, Hiroyuki Kano, Yasumasa Okazaki, Shinya Toyokuni, Shoichi Maruyama, Tetsuo Adachi, Hiroki Kaneko, Hiroko Terasaki, Yasuhiro Kodera, Fumitaka Kikkawa, and Masaru Hori
Organizer
the Third International Workshop on Plasma for Cancer Treatment (IWPCT 2016)
Place of Presentation
Embassy Suites by Hilton Washington DC Convention Center
Year and Date
2016-04-11 – 2016-04-16
Int'l Joint Research / Invited
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[Presentation] Plasma Activated Medium for Cancer Therapy2016
Author(s)
M. Hori, H.Tanaka, K.Ishikawa, M.Mizuno, F. Kikkawa
Organizer
Energy, Materials, and Nanotechnology (EMN) Meeting on Biomaterials
Place of Presentation
Phiket, Thailand
Year and Date
2016-04-04 – 2016-04-07
Int'l Joint Research / Invited
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