生殖細胞のエピゲノムダイナミクスとその制御

2016 Fiscal Year Annual Research Report

• Project Area: Analyses and regulation of germline epigenome
• Project/Area Number: 25112001
• Research Institution: Kyoto University
• Principal Investigator: 篠原 隆司 京都大学, 医学研究科, 教授 (30322770)
• Co-Investigator(Kenkyū-buntansha): 伊川 正人 大阪大学, 微生物病研究所, 教授 (20304066)
• Project Period (FY): 2013-06-28 – 2018-03-31
• Keywords: 生殖細胞

Outline of Annual Research Achievements

昨年度行われた中間評価において、「概ね計画通り、あるいは計画以上の成果が挙げられている」と評価を受けた一方で、研究分野が近い他の新学術領域研究との連携を期待したいとのコメントがあったことから、本年度は特にこの点に重点をおいて活動を強化した。具体的には、まずは総括班活動として若手合宿を2016年7月27日から29日まで大分県別府で行った際に「ステムセルエイジングから解明する疾患原理」(幹細胞エイジング班)班と共催を行った。若手合宿では63名が参加し、2名の研究者がベストプレゼンテーター賞を受賞した。これに引き続き、同年11月16-17日にも静岡県三島においての公開シンポジウムも幹細胞エイジング班と共同で行った。シンポジウム参加者は79名であった。両方の会議においても、二つの領域の合同となったために、これまでとは異なった角度からでの意見交換がなされたのみならず、幹細胞エイジング班の領域代表の岩間厚先生とは領域の運営や方向性について意見を交わすことができた。さらにこれに加えて本領域の国際支援班で海外より来日したDr. John R. McCarrey博士と共同で「動物における配偶子産生システムの制御」班と交流を行い、とくに精子形成を研究対象とするメンバー3名と研究打ち合わせを行った。3週間あまりの滞在期間で既存のコミュニティーの枠を超えた共同研究の打ち合わせや議論は双方の研究領域の進展に大きく寄与するものであった。中間評価でいただいたコメントの中でもう一つ問題となった若手研究者の論文の取りまとめや融合研究の促進については、三島で行われた総括班メンバーとの会議の際にも取り上げられ、班外の総括班メンバーからのアドバイスを受け、議論を行った。シニアメンバーからのサポートについては引き続き行っていく予定である。

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

中間審査で指摘いただいたコメントに予想よりも早く対応できた。

Strategy for Future Research Activity

今年度ステムセイルエイジング班と共同で行った若手勉強会が極めて好評であった。このため、来年度も再度同領域との共催を行う予定であるが、研究領域の近いもう一つの班である、「動的クロマチン構造と機能」（胡桃坂仁志代表）とも相談し、３つの班の合同で合同開催する予定となった（和歌山県白浜市）。「動的クロマチン構造と機能」領域とは本領域メンバーと既に共著論文も発表されていることから、より密接な相互作用が期待される。

また公開シンポジウムにおいても「配偶子班」との国際シンポジウムが予定されている（福岡県博多市）。本領域の計画班メンバーのみならず公募班メンバーも参加する予定である。

Research Products

• [Int'l Joint Research] University of Delaware/Baylor Collage of Medicine/ペンシルバニア大学(米国)
  • Country Name: U.S.A.
  • Counterpart Institution: University of Delaware/Baylor Collage of Medicine/ペンシルバニア大学
  • # of Other Institutions: 3
• [Int'l Joint Research] EMBL/モンペリエ大学(フランス)
  • Country Name: FRANCE
  • Counterpart Institution: EMBL/モンペリエ大学
• [Int'l Joint Research] マックスプランク研究所/マーバーグ大学(ドイツ)
  • Country Name: GERMANY
  • Counterpart Institution: マックスプランク研究所/マーバーグ大学
• [Int'l Joint Research] 台湾中央研究院(台湾)
  • Country Name: その他の国・地域
  • Counterpart Institution: 台湾中央研究院
• [Int'l Joint Research] ブリテッシュコロンンビア大学(カナダ)
  • Country Name: CANADA
  • Counterpart Institution: ブリテッシュコロンンビア大学
• [Int'l Joint Research]
  • # of Other Countries: 3
• [Journal Article] Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes. (2017)
  • Author(s): Kabayama Y, Toh H, Katanaya A, Sakurai T, Chuma S, Kuramochi-Miyagawa S, Saga Y, Nakano T, Sasaki H.
  • Journal Title: Nucleic Acids Res Volume: 45(9) Pages: 5387-5398
  • DOI: 10.1093/nar/gkx027.
  • Peer Reviewed / Open Access
• [Journal Article] Long non-coding RNA exchange during the oocyte-to-embryo transition in mice. (2017)
  • Author(s): Karlic R, Ganesh S, Franke V, Svobodova E, Urbanova J, Suzuki Y, Aoki F, Vlahovicek K, Svoboda P.
  • Journal Title: DNA Res Volume: 24(2) Pages: 129-141
  • DOI: 10.1093/dnares/dsw058.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Adeno-associated virus-mediated delivery of genes to mouse spermatogonial stem cells. (2017)
  • Author(s): Watanabe S, Kanatsu-Shinohara M, Ogonuki N, Matoba S, Ogura A, Shinohara T.
  • Journal Title: Biol Reprod Volume: 96 Pages: 221-231
  • DOI: 10.1095/biolreprod.116.143495
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] The mechanics clarifying counterclockwise rotation in most IVF eggs in mice. (2017)
  • Author(s): Ishimoto K, Ikawa M, Okabe M.
  • Journal Title: Sci Rep. Volume: 7 Pages: 43456
  • DOI: 10.1038/srep43456.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice. (2017)
  • Author(s): Naruse C, Shibata S, Tamura M, Kawaguchi T, Abe K, Sugihara K, Kato T, Nishiuchi T, Waianae S, Ikawa M, Asano M.
  • Journal Title: FASEB J. Volume: - Pages: -
  • DOI: 10.1096/fj.201600642R.
  • Peer Reviewed / Open Access
• [Journal Article] Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186. (2017)
  • Author(s): Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K.
  • Journal Title: Mucosal Immunol. Volume: 10(2) Pages: 446-459
  • DOI: 10.1038/mi.2016.58.
  • Peer Reviewed
• [Journal Article] Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis. (2017)
  • Author(s): Ueda J, Harada A, Urahama T, Machida S, Maehara K, Hada M, Makino Y, Nogami J, Horikoshi N, Osakabe A, Taguchi H, Tanaka H, Tachiwana H, Yao T, Yamada M, Iwamoto T, Isotani A, Ikawa M, Tachibana T, Okada Y, Kimura H, Ohkawa Y, Kurumizaka H, Yamagata K.
  • Journal Title: Cell Rep. Volume: 18(3) Pages: 593-600
  • DOI: 10.1016/j.celrep.2016.12.065.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition. (2017)
  • Author(s): Ishikawa T, Kitaura Y, Kadota Y, Morishita Y, Ota M, Yamanaka F, Xu M, Ikawa M, Inoue N, Kawano F, Nakai N, Murakami T, Miura S, Hatazawa Y, Kamei Y, Shimomura Y.
  • Journal Title: Sci Rep. Volume: 7 Pages: 39825
  • DOI: 10.1038/srep39825.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Naive Conversion. (2017)
  • Author(s): Honda A, Kawano Y, Izu H, Choijookhuu N, Honsho K, Nakamura T, Yabuta Y, Yamamoto T, Takashima Y, Hirose M, Sankai T, Hishikawa Y, Ogura A, Saitou M.
  • Journal Title: Sci Rep. Volume: 7 Pages: 45285
  • DOI: 10.1038/srep45285.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene. (2017)
  • Author(s): Hirose M, Hasegawa A, Mochida K, Matoba S, Hatanaka Y, Inoue K, Goto T, Kaneda H, Yamada I, Furuse T, Abe K, Uenoyama Y, Tsukamura H, Wakana S, Honda A, Ogura A.
  • Journal Title: Sci Rep. Volume: 7 Pages: 42476
  • DOI: 10.1038/srep42476.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction. (2017)
  • Author(s): Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, Tanaka H, Kondo T, Miyado K, Miyasaka N, Kubota T, Ogura A, Asahara H.
  • Journal Title: PLoS Genet. Volume: 13(1) Pages: e1006578
  • DOI: 10.1371/journal.pgen.1006578.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution. (2017)
  • Author(s): Kawasaki Y, Kuroda Y, Suetake I, Tajima S, Ishino F, Kohda T.
  • Journal Title: Nucleic Acids Res. Volume: 45(4) Pages: e24
  • DOI: 10.1093/nar/gkw994.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing. (2017)
  • Author(s): Toh H, Shirane K, Miura F, Kubo N, Ichiyanagi K, Hayashi K, Saitou M, Suyama M, Ito T, Sasaki H.
  • Journal Title: BMC Genomics. Volume: 18 Pages: 31
  • DOI: 10.1186/s12864-016-3392-9
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Factors associated with aberrant imprint methylation and oligozoospermia. (2017)
  • Author(s): Kobayashi N, Miyauchi N, Tatsuta N, Kitamura A, Okae H, Hiura H, Sato A, Utsunomiya T, Yaegashi N, Nakai K, Arima T.
  • Journal Title: Sci Rep. Volume: 7 Pages: 42336
  • DOI: 10.1038/srep42336.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Drospirenone reduces inflammatory cytokines, vascular endothelial growth factor (VEGF) and nerve growth factor (NGF) expression in human endometriotic stromal cells. (2017)
  • Author(s): Makabe T, Koga K, Miyashita M, Takeuchi A, Sue F, Taguchi A, Urata Y, Izumi G, Takamura M, Harada M, Hirata T, Hirota Y, Wada-Hiraike O, Fujii T, Osuga Y.
  • Journal Title: Reprod Immunol. Volume: 119 Pages: 44-48
  • DOI: 10.1016/j.jri.2016.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Mannose receptor is highly expressed by peritoneal dendritic cells in endometriosis. (2017)
  • Author(s): Izumi G, Koga K, Takamura M, Makabe T, Nagai M, Urata Y, Harada M, Hirata T, Hirota Y, Fujii T, Osuga Y.
  • Journal Title: Fertil Steril. Volume: 107(1) Pages: 167-173
  • DOI: 10.1016/j.fertnstert.2016.09.036.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Identification of the Doublesex protein binding sites that activate expression of lozenge in the female genital disc in Drosophila melanogaster. (2017)
  • Author(s): Wagamitsu S, Takase D, Aoki F, Suzuki MG.
  • Journal Title: Mech Dev. Volume: 143 Pages: 26-31
  • DOI: 10.1016/j.mod.2017.01.001.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. (2017)
  • Author(s): Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose R, Koseki H.
  • Journal Title: Elife. Volume: 6 Pages: e21064
  • DOI: 10.7554/eLife.21064.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryos. (2017)
  • Author(s): Ishiguro K, Nakatake Y, Chikazawa-Nohtomi N, Kimura H, Akiyama T, Oda M, Ko SBH, Ko MSH.
  • Journal Title: In Vitro Cell.Dev.Biol.-Anim. Volume: 53(2) Pages: 179-190.
  • DOI: 10.1007/s11626-016-0097-y.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis (2017)
  • Author(s): Ishiguro K, Monti M, Akiyama T, Kimura H, Chikazawa-Nohtomi N, Sakota M, Sato S, Redi CA, Ko SBH, Ko MSH.
  • Journal Title: In Vitro Cell.Dev.Biol. Volume: 53(2) Pages: 167-178
  • DOI: 10.1007/s11626-016-0096-z
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b. (2017)
  • Author(s): Padavattan S, Thiruselvam V, Shinagawa T, Hasegawa K, Kumasaka T, Ishii S, Kumarevel T.
  • Journal Title: Biophys Chem. Volume: 221 Pages: 41-48
  • DOI: 10.1016/j.bpc.2016.11.013.
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways. (2017)
  • Author(s): Jullien J, Vodnala M, Pasque V, Oikawa M, Miyamoto K, Allen G, David SA, Brochard V, Wang S, Bradshaw C, Koseki H, Sartorelli V, Beaujean N, Gurdon J.
  • Journal Title: Mol Cell. Volume: 65(5) Pages: 873-884
  • DOI: 10.1016/j.molcel.2017.01.030.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Periostin Promotes Scar Formation through the Interaction between Pericytes and Infiltrating Monocytes/Macrophages after Spinal Cord Injury. (2017)
  • Author(s): Yokota K, Kobayakawa K, Saito T, Hara M, Kijima K, Ohkawa Y, Harada A, Okazaki K, Ishihara K, Yoshida S, Kudo A, Iwamoto Y, Okada S.
  • Journal Title: Am J Pathol. Volume: 187(3) Pages: 639-653
  • DOI: 10.1016/j.ajpath.2016.11.010.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Development of reproductive engineering techniques at the RIKEN BioResource Center. (2017)
  • Author(s): Ogura A.
  • Journal Title: Exp Anim. Volume: 66(1) Pages: 1-16
  • DOI: 10.1538/expanim.16-0074.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Does MAX open up a new avenue for meiotic research? (2017)
  • Author(s): Suzuki A, Hirasaki M, Okuda A.
  • Journal Title: Dev Growth Differ Volume: 59 Pages: 61-69
  • Peer Reviewed / Open Access
• [Journal Article] A unique mechanism regulating gene expression in 1-cell embryos. (2017)
  • Author(s): Yamamoto R, Aoki F.
  • Journal Title: J Reprod Dev. Volume: 63(1) Pages: 9-11
  • DOI: 10.1262/jrd.2016-133.
  • Peer Reviewed / Open Access
• [Journal Article] Nuclear actin in development and transcriptional reprogramming. (2017)
  • Author(s): Misu S, Takebayashi M, Miyamoto K.
  • Journal Title: Front Genet. Volume: Vol 8 Pages: 27
  • DOI: 10.3389/fgene.2017.00027
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells. (2017)
  • Author(s): Hoshi R, Watanabe Y, Ishizuka Y, Hirano T, Nagasaki-Maeoka E, Yoshizawa S, Uekusa S, Kawashima H, Ohashi K, Sugito K, Fukuda N, Nagase H, Soma M. Ozaki T, Koshinaga T, Fujiwara K.
  • Journal Title: ONCOLOGY REPORTS Volume: 37 Pages: 2459-2464
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Automated detection and tracking of cell clusters in time-lapse fluorescence microscopy images. (2017)
  • Author(s): Chang YH, Yokota H, Abe K, Tang CT, Tsai MD.
  • Journal Title: Journal of Medical and Biological Engineering Volume: 37 Pages: 18-25
  • DOI: 10.1007/s40846-016-0216-y
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Conserved role of Ovo in germline development in mouse and Drosophila (2017)
  • Author(s): Hayashi M, Shinozuka Y, Shigenobu S, Sato M, Sugimoto M, Ito S, Abe K, Kobayashi S.
  • Journal Title: Sci Rep. Volume: 7 Pages: 40056
  • DOI: 10.1038/srep40056.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming. (2016)
  • Author(s): Wu Q, Fukuda K, Kato Y, Zhou Z, Deng CX, Saga Y.
  • Journal Title: PLoS Biol. Volume: 14(9) Pages: e1002553
  • DOI: 10.1371/journal.pbio.1002553.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells. (2016)
  • Author(s): Kato Y, Katsuki T, Kokubo H, Masuda A, Saga Y.
  • Journal Title: Nat Commun. Volume: 7 Pages: 11272
  • DOI: 10.1038/ncomms11272.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal. (2016)
  • Author(s): Kanatsu-Shinohara M, Tanaka T, Ogonuki N, Ogura A, Morimoto H, Cheng PF, Eisenman RN, Trumpp A, Shinohara T.
  • Journal Title: Genes Dev. Volume: 30(23) Pages: 2637-2648
  • DOI: 10.1101/gad.287045.116.
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells. (2016)
  • Author(s): Tanaka T, Kanatsu-Shinohara M, Lei Z, Rao CV, Shinohara T.
  • Journal Title: Stem Cell Reports. Volume: 7(2) Pages: 279-91
  • DOI: 10.1016/j.stemcr.2016.07.005.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Nonrandom Germline Transmission of Mouse Spermatogonial Stem Cells. (2016)
  • Author(s): Kanatsu-Shinohara M, Naoki H, Shinohara T.
  • Journal Title: Dev Cell. Volume: 38(3) Pages: 248-61
  • DOI: 10.1016/j.devcel.2016.07.011.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Fertility of Male Germline Stem Cells Following Spermatogonial Transplantation in Infertile Mouse Models. (2016)
  • Author(s): Kanatsu-Shinohara M, Morimoto H, Shinohara T.
  • Journal Title: Biol Reprod. Volume: 94(5) Pages: 112
  • DOI: 10.1095/biolreprod.115.137869.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Piwi Modulates Chromatin Accessibility by Regulating Multiple Factors Including Histone H1 to Repress Transposons. (2016)
  • Author(s): Iwasaki YW, Murano K, Ishizu H, Shibuya A, Iyoda Y, Siomi MC, Siomi H, Saito K.
  • Journal Title: Mol Cell. Volume: 63(3) Pages: 408-19
  • DOI: 10.1016/j.molcel.2016.06.008.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Inheritance of a Nuclear PIWI from Pluripotent Stem Cells by Somatic Descendants Ensures Differentiation by Silencing Transposons in Planarian. (2016)
  • Author(s): Shibata N, Kashima M, Ishiko T, Nishimura O, Rouhana L, Misaki K, Yonemura S, Saito K, Siomi H, Siomi MC, Agata K.
  • Journal Title: Dev Cell. Volume: 37(3) Pages: 226-37
  • DOI: 10.1016/j.devcel.2016.04.009.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Folic Acid Deficiency Does Not Adversely Affect Oocyte Meiosis in Mice. (2016)
  • Author(s): Tsuji A, Noguchi R, Nakamura T, Shibata K.
  • Journal Title: J Nutr Sci Vitaminol . Volume: 62(6): Pages: 375-379
  • DOI: 10.3177/jnsv.62.375.
  • Peer Reviewed
• [Journal Article] Reprogramming of germ cells into pluripotency. (2016)
  • Author(s): Sekita Y, Nakamura T, Kimura T.
  • Journal Title: World J Stem Cells. Volume: 8(8) Pages: 251-9
  • DOI: 10.4252/wjsc.v8.i8.251.
  • Peer Reviewed
• [Journal Article] High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice. (2016)
  • Author(s): Okai S, Usui F, Yokota S, Hori-I Y, Hasegawa M, Nakamura T, Kurosawa M, Okada S, Yamamoto K, Nishiyama E, Mori H, Yamada T, Kurokawa K, Matsumoto S, Nanno M, Naito T, Watanabe Y, Kato T, Miyauchi E, Ohno H, Shinkura R.
  • Journal Title: Nat Microbiol. Volume: 1(9) Pages: 16103
  • DOI: 10.1038/nmicrobiol.2016.103.
  • Peer Reviewed
• [Journal Article] A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO. (2016)
  • Author(s): Lee GH, Fujita M, Takaoka K, Murakami Y, Fujihara Y, Kanzawa N, Murakami KI, Kajikawa E, Takada Y, Saito K, Ikawa M, Hamada H, Maeda Y, Kinoshita T.
  • Journal Title: J Cell Biol. Volume: 215(5) Pages: 705-718
  • DOI: 10.1083/jcb.201605121
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa. (2016)
  • Author(s): Young SA, Miyata H, Satouh Y, Aitken RJ, Baker MA, Ikawa M.
  • Journal Title: J Cell Sci. Volume: 129(23) Pages: 4379-4387
  • DOI: 10.1242/jcs.193151
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility. (2016)
  • Author(s): Young SA, Miyata H, Satouh Y, Muto M, Larsen MR, Aitken RJ, Baker MA, Ikawa M.
  • Journal Title: Reproduction. Volume: 152(6) Pages: 665-672
  • DOI: 10.1530/REP-16-0150
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation. (2016)
  • Author(s): Takashima K, Takeda Y, Oshiumi H, Shime H, Okabe M, Ikawa M, Matsumoto M, Seya T.
  • Journal Title: Biochem Biophys Res Commun. Volume: 478(4) Pages: 1764-71
  • DOI: 10.1016/j.bbrc.2016.09.021.
  • Peer Reviewed / Open Access
• [Journal Article] CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice. (2016)
  • Author(s): Oji A, Noda T, Fujihara Y, Miyata H, Kim YJ, Muto M, Nozawa K, Matsumura T, Isotani A, Ikawa M.
  • Journal Title: Sci Rep. Volume: 6 Pages: 31666.
  • DOI: 10.1038/srep31666.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization. (2016)
  • Author(s): Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O.
  • Journal Title: Nat Commun. Volume: 7 Pages: 12198
  • DOI: 10.1038/ncomms12198.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis. (2016)
  • Author(s): Shimada M, Goshima T, Matsuo H, Johmura Y, Haruta M, Murata K, Tanaka H, Ikawa M, Nakanishi K, Nakanishi M.
  • Journal Title: Nat Commun. Volume: 7 Pages: 12059
  • DOI: 10.1038/ncomms12059
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. (2016)
  • Author(s): Miyata H, Castaneda JM, Fujihara Y, Yu Z, Archambeault DR, Isotani A, Kiyozumi D, Kriseman ML, Mashiko D, Matsumura T, Matzuk RM, Mori M, Noda T, Oji A, Okabe M, Prunskaite-Hyyrylainen R, Ramirez-Solis R, Satouh Y, Zhang Q, Ikawa M, Matzuk MM.
  • Journal Title: Proc Natl Acad Sci U S A. Volume: 113(28) Pages: 7704-10
  • DOI: 10.1073/pnas.1608458113.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse. (2016)
  • Author(s): Kanemori Y, Koga Y, Sudo M, Kang W, Kashiwabara S, Ikawa M, Hasuwa H, Nagashima K, Ishikawa Y, Ogonuki N, Ogura A, Baba T.
  • Journal Title: Proc Natl Acad Sci U S A. Volume: 113(26) Pages: E3696-705
  • DOI: 10.1073/pnas.1522333113.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Complementary role of CNNM2 in sperm motility and Ca(2+) influx during capacitation. (2016)
  • Author(s): Yamazaki D, Funato Y, Miyata H, Ikawa M, Miki H.
  • Journal Title: Biochem Biophys Res Commun. Volume: 474(3) Pages: 441-6
  • DOI: 10.1016/j.bbrc.2016.05.001
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Human HLA-Ev (147) Expression in Transgenic Animals. (2016)
  • Author(s): Matsuura R, Maeda A, Sakai R, Eguchi H, Lo PC, Hasuwa H, Ikawa M, Nakahata K, Zenitani M, Yamamichi T, Umeda S, Deguchi K, Okuyama H, Miyagawa S.
  • Journal Title: Transplant Proc. Volume: 48(4) Pages: 1323-5
  • DOI: 10.1016/j.transproceed.2015.10.069.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Knockout of Cytidine Monophospho-N-Acetylneuraminic Acid (CMP-NeuAc) Hydroxylase From Porcine Endothelial Cells by a CRISPR System. (2016)
  • Author(s): Sakai R, Esaki Y, Hasuwa H, Ikawa M, Lo P, Matsuura R, Nakahata K, Zenitani M, Asada M, Maeda A, Eguchi H, Okuyama H, Miyagawa S.
  • Journal Title: Transplant Proc. Volume: 48(4) Pages: 1320-2
  • DOI: 10.1016/j.transproceed.2015.10.065
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Expression of a Synthetic Gene of CTDM by Transgenic Animals. (2016)
  • Author(s): Sakai R, Maeda A, Matsuura R, Eguchi H, Lo P, Hasuwa H, Ikawa M, Nakahata K, Zenitani M, Yamamichi T, Umeda S, Okuyama H, Miyagawa S.
  • Journal Title: Transplant Proc. Volume: 48(4) Pages: 1279-81
  • DOI: Transplant Proc.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] The Mg2+ transporter CNNM4 regulates sperm Ca2+ homeostasis and is essential for reproduction. (2016)
  • Author(s): Yamazaki D, Miyata H, Funato Y, Fujihara Y, Ikawa M, Miki H.
  • Journal Title: J Cell Sci. Volume: 129(9) Pages: 1940-9
  • DOI: 10.1242/jcs.182220.
  • Peer Reviewed / Open Access
• [Journal Article] Generation of Hprt-disrupted rat through mouse←rat ES chimeras. (2016)
  • Author(s): Isotani A, Yamagata K, Okabe M, Ikawa M.
  • Journal Title: Sci Rep. Volume: 6 Pages: 24215
  • DOI: 10.1038/srep24215.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. (2016)
  • Author(s): Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, Daa T, Iha H, Takahashi M, Nomura T, Sato F, Mimata H, Ikawa M, Seto M, Matsuura K, Moriyama M.
  • Journal Title: J Pathol. Volume: 239(1) Pages: 97-108
  • DOI: 10.1002/path.4706.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Behavior of Mouse Spermatozoa in the Female Reproductive Tract from Soon after Mating to the Beginning of Fertilization. (2016)
  • Author(s): Muro Y, Hasuwa H, Isotani A, Miyata H, Yamagata K, Ikawa M, Yanagimachi R, Okabe M.
  • Journal Title: Biol Reprod. Volume: 94(4) Pages: 80
  • DOI: 10.1095/biolreprod.115.135368.
  • Peer Reviewed
• [Journal Article] Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders. (2016)
  • Author(s): Brukman NG, Miyata H, Torres P, Lombardo D, Caramelo JJ, Ikawa M, Da Ros VG, Cuasnicu PS.
  • Journal Title: Mol Hum Reprod. Volume: 22(4) Pages: 240-51
  • DOI: 10.1093/molehr/gaw005.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] MIWI2 as an Effector of DNA Methylation and Gene Silencing in Embryonic Male Germ Cells. (2016)
  • Author(s): Kojima-Kita K, Kuramochi-Miyagawa S, Nagamori I, Ogonuki N, Ogura A, Hasuwa H, Akazawa T, Inoue N, Nakano T.
  • Journal Title: Cell Rep. Volume: 16(11) Pages: 2819-28
  • DOI: 10.1016/j.celrep.2016.08.027.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells. (2016)
  • Author(s): Inoue H, Ogonuki N, Hirose M, Hatanaka Y, Matoba S, Chuma S, Kobayashi K, Wakana S, Noguchi J, Inoue K, Tanemura K, Ogura A.
  • Journal Title: Biochem Biophys Res Commun. Volume: 478(2) Pages: 592-8
  • DOI: 10.1016/j.bbrc.2016.07.109.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Cellular Dynamics of Mouse Trophoblast Stem Cells: Identification of a Persistent Stem Cell Type. (2016)
  • Author(s): Motomura K, Oikawa M, Hirose M, Honda A, Togayachi S, Miyoshi H, Ohinata Y, Sugimoto M, Abe K, Inoue K, Ogura A.
  • Journal Title: Biol Reprod. Volume: 94(6) Pages: 122
  • DOI: 10.1095/biolreprod.115.137125.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] In vitro derivation and propagation of spermatogonial stem cell activity from mouse pluripotent stem cells. (2016)
  • Author(s): Ishikura Y, Yabuta Y, Ohta H, Hayashi K, Nakamura T, Okamoto I, Yamamoto T, Kurimoto K, Shirane K, Sasaki H, Saitou M.
  • Journal Title: Cell Rep. Volume: 17(10) Pages: 2789-2804
  • DOI: 10.1016/j.celrep.2016.11.026.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Global landscape and regulatory principles of DNA methylation reprogramming for germ cell specification by mouse pluripotent stem cells. (2016)
  • Author(s): Shirane K, Kurimoto K, Yabuta Y, Yamaji M, Satoh J, Ito S, Watanabe A, Hayashi K, Saitou M, Sasaki H.
  • Journal Title: Dev Cell. Volume: 39(1) Pages: 87-103
  • DOI: 10.1016/j.devcel.2016.08.008.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] In vivo dynamics of GFRα1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay. (2016)
  • Author(s): Uchida A, Kishi K, Aiyama Y, Miura K, Takase HM, Suzuki H, Kanai-Azuma M, Iwamori T, Kurohmaru M, Tsunekawa N, Kanai Y.
  • Journal Title: Data Brief. Volume: 8 Pages: 1255-8
  • DOI: 10.1016/j.dib.2016.07.055.
  • Peer Reviewed / Open Access
• [Journal Article] Mouse Sox17 haploinsufficiency leads to female subfertility due to impaired implantation. (2016)
  • Author(s): Hirate Y, Suzuki H, Kawasumi M, Takase HM, Igarashi H, Naquet P, Kanai Y, Kanai-Azuma M.
  • Journal Title: Sci Rep. Volume: 6 Pages: 24171
  • DOI: 10.1038/srep24171.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency. (2016)
  • Author(s): Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, Kawaguchi M, Kashida H, Nakajima A, Tachibana M, Seki Y.
  • Journal Title: Stem Cell Reports. Volume: 7(6) Pages: 1072-1086
  • DOI: 10.1016/j.stemcr.2016.10.007.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Genome-Scale Assessment of Age-Related DNA Methylation Changes in Mouse Spermatozoa. (2016)
  • Author(s): Kobayashi N, Okae H, Hiura H, Chiba H, Shirakata Y, Hara K, Tanemura K, Arima T.
  • Journal Title: PLoS One. Volume: 11(11) Pages: e0167127
  • DOI: 10.1371/journal.pone.0167127.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta. (2016)
  • Author(s): Hamada H, Okae H, Toh H, Chiba H, Hiura H, Shirane K, Sato T, Suyama M, Yaegashi N, Sasaki H, Arima T.
  • Journal Title: Am J Hum Genet. Volume: 99(5) Pages: 1045-1058
  • DOI: 10.1016/j.ajhg.2016.08.021.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] A potential role for endoplasmic reticulum stress in progesterone deficiency in obese women. (2016)
  • Author(s): Takahashi N, Harada M, Hirota Y, Zhao L, Azhary JM, Yoshino O, Izumi G, Hirata T, Koga K, Wada-Hiraike O, Fujii T, Osuga Y.
  • Journal Title: Endocrinology. Volume: - Pages: en20161511
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Dienogest reduces proliferation, NGF expression and nerve fiber density in human adenomyosis. (2016)
  • Author(s): Takeuchi A, Koga K, Miyashita M, Makabe T, Sue F, Harada M, Hirata T, Hirota Y, Fujii T, Osuga Y.
  • Journal Title: Eur J Obstet Gynecol Reprod Biol. Volume: 207 Pages: 157-161
  • DOI: 10.1016/j.ejogrb.2016.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Reduced homeobox protein MSX1 in human endometrial tissue is linked to infertility. (2016)
  • Author(s): Bolnick AD, Bolnick JM, Kilburn BA, Stewart T, Oakes J, Rodriguez-Kovacs J, Kohan-Ghadr HR, Dai J, Diamond MP, Hirota Y, Drewlo S, Dey SK, Armant DR.
  • Journal Title: Hum Reprod. Volume: 31(9) Pages: 2042-50
  • DOI: 10.1093/humrep/dew143.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Neutrophil depletion reduces endometriotic lesion formation in mice. (2016)
  • Author(s): Takamura M, Koga K, Izumi G, Urata Y, Nagai M, Hasegawa A, Harada M, Hirata T, Hirota Y, Wada-Hiraike O, Fujii T, Osuga Y. Am J.
  • Journal Title: Reprod Immunol. Volume: 76(3) Pages: 193-8
  • DOI: 10.1111/aji.12540.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] p53 coordinates decidual sestrin 2/AMPK/mTORC1 signaling to govern parturition timing. (2016)
  • Author(s): Deng W, Cha J, Yuan J, Haraguchi H, Bartos A, Leishman E, Viollet B, Bradshaw HB, Hirota Y, Dey SK.
  • Journal Title: J Clin Invest. Volume: 126(8) Pages: 2941-54
  • DOI: 10.1172/JCI87715.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation. (2016)
  • Author(s): Hiraoka T, *Hirota Y, Saito-Fujita T, Matsuo M, Egashira M, Matsumoto L, Haraguchi H, Dey SK, Furukawa KS, Fujii T, Osuga Y.
  • Journal Title: JCI Insight. Volume: 1(8) Pages: e87591.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Effects of 1,25-Dihydroxy Vitamin D3 on Endometriosis. (2016)
  • Author(s): Miyashita M, Koga K, Izumi G, Sue F, Makabe T, Taguchi A, Nagai M, Urata Y, Takamura M, Harada M, Hirata T, Hirota Y, Wada-Hiraike O, Fujii T, Osuga Y.
  • Journal Title: J Clin Endocrinol Metab. Volume: 101(6) Pages: 2371-9
  • DOI: 10.1210/jc.2016-1515.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] A potential role of endoplasmic reticulum stress in development of ovarian hyperstimulation syndrome. (2016)
  • Author(s): Takahashi N, Harada M, Hirota Y, Zhao L, Yoshino O, Urata Y, Izumi G, Takamura M, Hirata T, Koga K, Wada-Hiraike O, Fujii T, Osuga Y.
  • Journal Title: Mol Cell Endocrinol. Volume: 428 Pages: 161-9
  • DOI: 10.1016/j.mce.2016.03.032.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Resveratrol Enhances Apoptosis in Endometriotic Stromal Cells. (2016)
  • Author(s): Taguchi A, Koga K, Kawana K, Makabe T, Sue F, Miyashita M, Yoshida M, Urata Y, Izumi G, Tkamura M, Harada M, Hirata T, Hirota Y, Wada-Hiraike O, Fujii T, Osuga Y.
  • Journal Title: Am J Reprod Immunol. Volume: 75(4) Pages: 486-92
  • DOI: 10.1111/aji.12489.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori. (2016)
  • Author(s): Sakai H, Sumitani M, Chikami Y, Yahata K, Uchino K, Kiuchi T, Katsuma S, Aoki F, Sezutsu H, Suzuki MG.
  • Journal Title: PLoS Genet. Volume: 12(8) Pages: e1006203
  • DOI: 10.1371/journal.pgen.1006203.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Analysis of chromatin structure in mouse preimplantation embryos by fluorescent recovery after photobleaching. (2016)
  • Author(s): Ooga M, Fulka H, Hashimoto S, Suzuki MG, Aoki F.
  • Journal Title: Epigenetics. Volume: 11(1) Pages: 85-94
  • DOI: 10.1080/15592294.2015.1136774.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Characterization of gene expression in mouse embryos at the 1-cell stage. (2016)
  • Author(s): Yamamoto R, Abe K, Suzuki Y, Suzuki MG, Aoki F.
  • Journal Title: J Reprod Dev. Volume: 62(1) Pages: 87-92
  • DOI: 10.1262/jrd.2015-131.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program. (2016)
  • Author(s): Ikawa T, Masuda K, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H.
  • Journal Title: Genes Dev. Volume: 30(22) Pages: 2475-2485
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Production of Small Noncoding RNAs from the flamenco Locus Is Regulated by the gypsy Retrotransposon of Drosophila melanogaster. (2016)
  • Author(s): Guida V, Cernilogar FM, Filograna A, De Gregorio R, Ishizu H, Siomi MC, Schotta G, Bellenchi GC, Andrenacci D.
  • Journal Title: Genetics. Volume: 204(2) Pages: 631-644
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] A HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia (2016)
  • Author(s): Chakraborty D, Cui W, Rosario GX, Scott RL, Dhakal P, Renaud SJ, Tachibana M, Rumi MAK, Mason CW, Krieg A, Soares MJ.
  • Journal Title: Proc Natl Acad Sci U S A. Volume: 113(46) Pages: E7212-E7221
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Pericentric H3K9me3 formation by HP1 interaction-defective histone methyltransferase Suv39h1. (2016)
  • Author(s): Muramatsu D, Kimura H, Kuboshita K, Tachibana M, Shinkai Y.
  • Journal Title: Cell Struct Funct. Volume: 41(2) Pages: 145-152
  • Peer Reviewed / Open Access
• [Journal Article] Sperm is epigenetically programmed to regulate gene transcription in embryos. (2016)
  • Author(s): Teperek M, Simeone A, Gaggioli V, Miyamoto K, Allen GE, Erkek S, Kwon T, Marcotte EM, Zegerman P, Bradshaw CR, Peters AH, Gurdon JB, Jullien J.
  • Journal Title: Genome Res. Volume: 26(8) Pages: 1034-46
  • DOI: 10.1101/gr.201541.115.
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Bayesian Inference of Forces Causing Cytoplasmic Streaming in Caenorhabditis elegans Embryos and Mouse Oocytes. (2016)
  • Author(s): Niwayama R, Nagao H, Kitajima TS, Hufnagel L, Shinohara K, Higuchi T, Ishikawa T, Kimura A.
  • Journal Title: PLoS One. Volume: 11(7) Pages: e0159917
  • DOI: 10.1371/journal.pone.0159917.
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Identification of Immunoglobulin Gene Sequences from a Small Read Number of mRNA-Seq Using Hybridomas. (2016)
  • Author(s): Kuniyoshi Y, Maehara K, Iwasaki T, Hayashi M, Semba Y, Fujita M, Sato Y, Kimura H, Harada A, Ohkawa Y.
  • Journal Title: PLoS One. Volume: 11(10) Pages: e0165473
  • DOI: 10.1371/journal.pone.0165473.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Histone H4 lysine 20 acetylation is associated with gene repression in human cells. (2016)
  • Author(s): Kaimori JY, Maehara K, Hayashi-Takanaka Y, Harada A, Fukuda M, Yamamoto S, Ichimaru N, Umehara T, Yokoyama S, Matsuda R, Ikura T, Nagao K, Obuse C, Nozaki N, Takahara S, Takao T, Ohkawa Y, Kimura H, Isaka Y.
  • Journal Title: Sci Rep. Volume: 6 Pages: 24318
  • DOI: 10.1038/srep24318.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] エピゲノム異常が疑われる際の解析方法． (2016)
  • Author(s): 樺山由佳，佐々木裕之
  • Journal Title: マウス表現型解析スタンダード Volume: 実験医学別冊 Pages: 267-274
• [Journal Article] GPI-AP release in cellular, developmental, and reproductive biology. (2016)
  • Author(s): Fujihara Y, Ikawa M.
  • Journal Title: J Lipid Res. Volume: 57(4) Pages: 538-45
  • DOI: 10.1194/jlr.R063032.
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Unexpected link between MAX and meiotic onset. (2016)
  • Author(s): Okuda A, Suzuki A.
  • Journal Title: Cell Cycle Volume: 15 Pages: 2235-2236
  • Peer Reviewed / Open Access
• [Journal Article] 発生および生体工学と生殖医療 子宮の再生 (2016)
  • Author(s): 古川克子、廣田泰、吉野修、岸田晶夫、牛田多加志、齋藤滋、大須賀穣．
  • Journal Title: HORMONE FRONTIER IN GYNECOLOGY. Volume: 23(2) Pages: 161-5
• [Journal Article] Nucleolus Precursor Bodies and Ribosome Biogenesis in Early Mammalian Embryos: Old Theories and New Discoveries. (2016)
  • Author(s): Fulka H, Aoki F.
  • Journal Title: Biol Reprod Volume: 94(6) Pages: 143
  • DOI: 10.1095/biolreprod.115.136093.
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Epigenetics of Sex Determination in Mammals (2016)
  • Author(s): Tachibana M.
  • Journal Title: Reproductive Medicine and Biology Volume: 15 Pages: 59-67
  • Peer Reviewed
• [Journal Article] The cohesin REC8 prevents illegitimate inter-sister synaptonemal complex. (2016)
  • Author(s): Ishiguro K, Watanabe Y.
  • Journal Title: EMBO reports. Volume: 17(6) Pages: 783-4
  • DOI: 10.15252/embr.201642544.
  • Open Access
• [Journal Article] A new era of human assisted reproductive technology. (2016)
  • Author(s): Miyamoto K.
  • Journal Title: Journal of Mammalian Ova Research. Volume: Vol. 33(2) Pages: 77
  • DOI: 10.1274/jmor.33.77
• [Journal Article] Live Imaging of Intracellular Dynamics During Meiotic Maturation in Mouse Oocytes. (2016)
  • Author(s): Yoshida S, Sakakibara Y, Kitajima TS.
  • Journal Title: Methods Mol Biol. Volume: 1457 Pages: 241-51
  • DOI: 10.1007/978-1-4939-3795-0_18.
• [Journal Article] Targeting Oct1 genomic function inhibits androgen receptor signaling and castration-resistant prostate cancer growth (2016)
  • Author(s): Obinata D, Takayama K, Fujiwara K, Suzuki T, Tsutsumi S, Fukuda N, Nagase H, Fujimura T, Urano T, Homma Y, Aburatani H, Takahashi S, Inoue S.
  • Journal Title: Oncogene Volume: 35 Pages: 6350-6358
  • DOI: 10.1038/onc.2016.171
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Double β-alanine substitutions incorporated in 12-ring pyrrole-Imidazole Polyamides for lengthened DNA minor groove recognition. (2016)
  • Author(s): Watanabe T, Shinohara K, Shinozaki Y, Uekusa S, Wang X, Koshikawa N, Hiraoka K, Inoue T, Lin J, Bando T, Sugiyama H ,Nagase H.
  • Journal Title: Advanced Techniques in Biology & Medicine. Volume: 4 Pages: 175
  • DOI: 10.4172/2379-1764.1000175.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] NLRR2 inhibits cell differentiation by transcriptional induction through JNK pathway. (2016)
  • Author(s): Sheikh A, Takatori A, Hossain MS, Hasan MK, Tagawa M, Nagase H, Nakagawara A.
  • Journal Title: Unfavorable neuroblastoma prognostic factor Cancer Science Volume: 107(9) Pages: 1223-32
  • DOI: 10.1111/cas.13003.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome. (2016)
  • Author(s): Lin J, Hiraoka K, Watanabe T, Kuo T, Shinozaki Y, Takatori A, Koshikawa N, Chandran A, Otsuki J, Sugiyama H, Horton P , Nagase H.
  • Journal Title: Plos One Volume: 11(10) Pages: e0165581
  • DOI: 10.1371/journal.pone.0165581
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] RAR-related orphan receptor α 1 is correlated with unfavorable clinicopathological features in patients with colorectal cancer. (2016)
  • Author(s): Kano H, Takayama T, Midorikawa Y, Nagase H.
  • Journal Title: Promoter hypomethylation of BioScience Trends. Volume: 10(3) Pages: 202-209
  • Peer Reviewed
• [Journal Article] Inhibition of DNA methylation at the MLH1 promoter region using pyrrole-imidazole polyamide. (2016)
  • Author(s): Shinohara K, Yoda N, Takane K, Watanabe T, Fukuyo M, Fujiwara K, Kita K, Nagase H, Nemoto T, Kaneda A.
  • Journal Title: ACS Omega Volume: 1 (6) Pages: 1164-1172
  • DOI: 10.1021/acsomega.6b00229
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Mutations in Japanese Ovarian Clear Cell Carcinoma Patients using Optimized Targeted NGS for Clinical Diagnosis. (2016)
  • Author(s): Maru Y, Tanaka N, Ohira M, Itami M, Hippo Y , Nagase H.
  • Journal Title: Identification of Novel Gynecologic Oncology Volume: - Pages: -
  • DOI: 10.1016/j.ygyno.2016.11.045.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Detection and localization of mouse induced pluripotent stem cell formation using time-lapse fluorescence microscopy images (2016)
  • Author(s): Chang YH, Yokota H, Abe K, Liu JH, Tsai MD.
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc. Volume: - Pages: 3914-3917
  • DOI: 10.1109/EMBC.2016.7591583.
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Fluorescence microscopy image processing and visualization for analyzing cell kinematics, proliferation and attachment in mouse embryonic stem cell culture (2016)
  • Author(s): Chang YH, Yokota H, Abe K, Li CC, Tsai MD.
  • Journal Title: IEEE 16th International Conference on Bioinformatics and Bioengineering (BIBE), Volume: - Pages: -
  • DOI: 10.1109/BIBE.2016.44
  • Peer Reviewed / Int'l Joint Research
• [Presentation] ポリコーム群遺伝子Pcgf6による生殖細胞特異的遺伝子の発現および胚発生の制御 (2017)
  • Author(s): 遠藤充浩.
  • Organizer: 千葉大学医学部
  • Place of Presentation: 千葉県千葉市
  • Year and Date: 2017-03-31
  • Invited
• [Presentation] ゲノム編集を利用した精巣特異的遺伝子の網羅的機能解析 (2017)
  • Author(s): 伊川正人.
  • Organizer: 第122回日本解剖学会総会・全国学術集会
  • Place of Presentation: 長崎県長崎市
  • Year and Date: 2017-03-28 – 2017-03-30
  • Invited
• [Presentation] Reconstitution of epigenetic rerpgramming pathway associated with primordial germ cells in embryonic stem cells (2017)
  • Author(s): Seki Y.
  • Organizer: CDB Symposium 2017
  • Place of Presentation: 兵庫県神戸市
  • Year and Date: 2017-03-27
• [Presentation] The causes of aneupolidy in eggs (2017)
  • Author(s): Kitajima T.
  • Organizer: 大阪大学 蛋白研セミナー
  • Place of Presentation: 大阪府吹田市
  • Year and Date: 2017-03-23
  • Invited
• [Presentation] ビタミン欠乏が卵母細胞の質におよぼす影響 (2017)
  • Author(s): 辻 愛、中村 肇伸、柴田 克己.
  • Organizer: 日本農芸化学会2017年大会
  • Place of Presentation: 京都府京都市
  • Year and Date: 2017-03-17
• [Presentation] Lentiviral Vector-Mediated Placenta-Specific Gene Manipulation in Mice (2017)
  • Author(s): Ikawa M.
  • Organizer: 64th SRI meeting
  • Place of Presentation: Florida, USA
  • Year and Date: 2017-03-15 – 2017-03-18
  • Int'l Joint Research / Invited
• [Presentation] Germ cell-specific conditional KO via Cas9-mediated chimera analyses (2017)
  • Author(s): Saga Y.
  • Organizer: The 20th US-Japan Cellular and Gene Therapy Conference CRISPR/Cas9 Gene Editing In Vivo.
  • Place of Presentation: Maryland, USA
  • Year and Date: 2017-03-09
  • Int'l Joint Research / Invited
• [Presentation] CRISPR/Cas9 Mediated Genome Editing and its Application for the Study of Reproduction (2017)
  • Author(s): Ikawa M.
  • Organizer: The 20th US-Japan Cellular and Gene Therapy Conference
  • Place of Presentation: Maryland, USA
  • Year and Date: 2017-03-09
  • Int'l Joint Research / Invited
• [Presentation] 金属メッシュデバイスによるマウスES細胞由来胚様体のサイズ分画法の検討 (2017)
  • Author(s): 長谷川 慎 、木村 七海、井上 有香、水上 民夫、佐々木 隆造、土田 美江、中村 肇伸、古田 明日香、三浦 佳子、神波 誠治、近藤 孝志.
  • Organizer: 第16回日本再生医療学会総会
  • Place of Presentation: 宮城県仙台市
  • Year and Date: 2017-03-07
• [Presentation] ヒドロキシメチルシトシン、メチルシトシンの新しい解析手法とその応用 (2017)
  • Author(s): 幸田尚.
  • Organizer: 日本農芸化学会2017年度大会シンポジウム
  • Place of Presentation: 京都府、京都市
  • Year and Date: 2017-03-02
  • Invited
• [Presentation] 卵子における染色体数異常の細胞生物学的な要因 (2017)
  • Author(s): 北島智也.
  • Organizer: 第23回ホルモン療法を考える神奈川県医師の会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2017-03-01
  • Invited
• [Presentation] Pyrrole-imidazole polyamide conjugates targeting the cancer genome. (2017)
  • Author(s): 永瀬浩喜
  • Organizer: 日本大学学部連携研究推進シンポジウム新規バイオ医療ピロール・イミダゾール(PI)ポリアミドの創薬開発 国際シンポジウム
  • Place of Presentation: 東京都千代田区
  • Year and Date: 2017-02-24
  • Int'l Joint Research / Invited
• [Presentation] Establishment of trophoblast stem cells from human placenta (2017)
  • Author(s): 岡江寛明.
  • Organizer: RIKEN SEMINAR
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-21
  • Invited
• [Presentation] Analysis of chromatin kinetics in developing male germ cells (2017)
  • Author(s): Yamanaka S.
  • Organizer: International meeting "Chromosome Orchestration System"
  • Place of Presentation: London
  • Year and Date: 2017-02-20 – 2017-02-21
  • Int'l Joint Research
• [Presentation] Target epigenetic regulation using Pyrrole-imidazole polyamide conjugates. (2017)
  • Author(s): 永瀬浩喜
  • Organizer: RIKEN Epigenetics in TsukubaRecent Advances in Epigenetic Engineering
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-17
  • Invited
• [Presentation] The causes of aneuploidy in eggs (2017)
  • Author(s): 北島智也
  • Organizer: RIKEN Epigenetics 2017
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-17
• [Presentation] Histone H3R17me2a mark recruits Tet3 to initiate active DNA demethylation in mouse zygotes (2017)
  • Author(s): 畑中勇輝, 清水なつみ, 守田昂太郎, 佐藤学, 本多新, 廣瀬美智子, 上村悟氏, 越後貫成美, 中村肇伸, 井上貴美子, 細井美彦, 仲野徹, 松本和也, 小倉淳郎.
  • Organizer: RIKEN Epigenetics 2017
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-16
• [Presentation] The rodent-specific microRNA cluster within the Sfmbt2 gene is imprinted and essential for placental development (2017)
  • Author(s): Inoue K, Hirose M, Inoue H, Hatanaka , Honda A, Hasegawa A, Mochida K, Ogura A.
  • Organizer: RIKEN Epigenetics 2017
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-16
• [Presentation] CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene (2017)
  • Author(s): 廣瀬美智子, 長谷川歩未，持田慶司, 的場章悟, 畑中勇輝, 井上貴美子, 後藤達彦, 金田秀貴, 山田郁子, 古瀬民生, 阿部訓也, 上野山賀久, 束村博子, 若菜茂晴, 本多新, 小倉淳郎.
  • Organizer: RIKEN Epigenetics1 2017
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-16
• [Presentation] Genome-wide analysis reveals incomplete reprogramming of DNA methylation in blastocysts created by somatic cell nuclear transfer (2017)
  • Author(s): 的場章悟, Shen L, 小倉淳郎, Zhang Y.
  • Organizer: RIKEN Epigenetics 2017
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-16
• [Presentation] Translated Protamine 1 by exogenous mRNAs remodals the nucleus of cumulus cell ready to be reprogrammed by the oocyte (2017)
  • Author(s): Iuso D, Hatanaka Y, Fidanza A, Chernik M, Loi P, Ogura A.
  • Organizer: RIKEN Epigenetics 2017
  • Place of Presentation: 茨城県つくば市
  • Year and Date: 2017-02-16
• [Presentation] Functional switching of histone H3 variants in myogenesis (2017)
  • Author(s): 原田哲仁.
  • Organizer: 第4回ヒストンバリアント研究会
  • Place of Presentation: 宮城県仙台市
  • Year and Date: 2017-02-11
  • Invited
• [Presentation] ゲノム編集による遺伝子改変マウス作製とその応用 (2017)
  • Author(s): 伊川正人.
  • Organizer: がん進展制御研究所セミナー
  • Place of Presentation: 石川県、金沢市
  • Year and Date: 2017-02-10
  • Invited
• [Presentation] A proteomic approach to developmental control of genome stability in pluripotent stem cells and differentiated cells in mice. (2017)
  • Author(s): Katanaya A, Hosokawa M, Hayashi E, Mochizuki A, Moribe E, Chuma S.
  • Organizer: Frontier of Biomolecular Mass Spectrometry.
  • Place of Presentation: Kyoto、Japan
  • Year and Date: 2017-02-07
  • Invited
• [Presentation] エピゲノム成立の分子メカニズムの解明と制御 (2017)
  • Author(s): 仲野 徹、中村 肇伸.
  • Organizer: CREST「エピゲノム研究に基づく診断・治療へ向けた新技術の創出」研究領域 第6回領域会議
  • Place of Presentation: 東京都
  • Year and Date: 2017-02-03
• [Presentation] Tet3とOGTが胚性遺伝子の活性化に及ぼす影響 (2017)
  • Author(s): 中村 肇伸、古田 明日香、仲野 徹.
  • Organizer: CREST「エピゲノム研究に基づく診断・治療へ向けた新技術の創出」研究領域 第6回領域会議
  • Place of Presentation: 東京都
  • Year and Date: 2017-02-03
• [Presentation] 細胞動態のイメージングと定量 (2017)
  • Author(s): 北島智也.
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2017-02-01
  • Invited
• [Presentation] エピジェネティック破綻により引き起こされた筋肉腫の解析 (2017)
  • Author(s): 原田哲仁.
  • Organizer: 公益財団法人福岡県すこやか健康事業団平成28年度がん研究助成金優秀賞受賞講演
  • Place of Presentation: 福岡県福岡市
  • Year and Date: 2017-01-30
  • Invited
• [Presentation] 生殖細胞によるエピゲノムリプログラミングと多能性誘導 (2017)
  • Author(s): 関 由行.
  • Organizer: 産業医科大学大学院セミナー
  • Place of Presentation: 福岡県北九州市
  • Year and Date: 2017-01-27
  • Invited
• [Presentation] Stage-dependent contribution of transcriptional and posttranscriptional mechanisms to retrotransposon silencing during male germ cell development in mice. (2017)
  • Author(s): Inoue K, Ichiyanagi K, Fukuda K, Glinka M , Sasaki H.
  • Organizer: 11th International Symposium of The Institute Network, “Frontiers in Biomedical Sciences”
  • Place of Presentation: Tokushima , Japan
  • Year and Date: 2017-01-26 – 2017-01-27
  • Int'l Joint Research
• [Presentation] Role of H3K9 methylation and demethylation enzymes in mouse development (2017)
  • Author(s): Kuroki S, Tachibana M.
  • Organizer: 11th International Symposium of The Institute Network, Frontiers in Biomedical Sciences
  • Place of Presentation: 徳島県、徳島市
  • Year and Date: 2017-01-26
  • Int'l Joint Research
• [Presentation] ゲノム編集による遺伝子改変マウス作成技術の開発とその応用 (2017)
  • Author(s): 伊川正人.
  • Organizer: 第21回日本生殖内分泌学会学術集会
  • Place of Presentation: 大阪府、豊中市
  • Year and Date: 2017-01-14
  • Invited
• [Presentation] 卵母細胞では動原体が紡錘体の二極化に必要である (2017)
  • Author(s): 吉田周平、北島智也
  • Organizer: 第34回染色体ワークショップ・第15回核ダイナミクス研究会
  • Place of Presentation: 千葉県木更津市
  • Year and Date: 2017-01-12
• [Presentation] ショウジョウバエpiRNAによるクロマチン制御機構 (2016)
  • Author(s): 齋藤都暁.
  • Organizer: 大阪大学蛋白質研究所セミナー
  • Place of Presentation: 大阪府、吹田市
  • Year and Date: 2016-12-21
  • Invited
• [Presentation] マウス生殖細胞の性分化制御機 (2016)
  • Author(s): 相賀裕美子.
  • Organizer: 筑波大学生命領域学際研究センター TARAセミナー
  • Place of Presentation: 茨城県、つくば市
  • Year and Date: 2016-12-16
  • Invited
• [Presentation] 国際リスク分類システムと連携した神経芽腫分子生物学的データベースの構築と高リスク神経芽腫のゲノム解析 (2016)
  • Author(s): 大平美紀、上條岳彦、瀧本哲也、中澤温子、松本公一、七野浩之、菱木知郎、家原知子、中村洋子、永瀬浩喜、米田光宏、福島敬、田尻達郎、中川原章
  • Organizer: 第58回日本小児血液・がん学会学術集会
  • Place of Presentation: 東京都品川区
  • Year and Date: 2016-12-15
• [Presentation] 難治性神経芽腫のゲノム・エピゲノム統合解析 (2016)
  • Author(s): 大平美紀、巽康年、中村洋子、龍野健二、堤修一、山本尚吾、永江玄太、Claire Renard-Guillet、杉野隆一、永瀬浩喜、上條岳彦、油谷浩幸、中川原章
  • Organizer: 第58回日本小児血液・がん学会学術集会
  • Place of Presentation: 東京都品川区
  • Year and Date: 2016-12-15
• [Presentation] MYCN遺伝子を標的としたPIポリアミドDNAアルキル化剤の抗腫瘍活性と安全性 (2016)
  • Author(s): 高取敦志、養田裕行、井上貴博、渡部隆義、越川信子、若菜茂晴、永瀬浩喜
  • Organizer: 第58回日本小児血液・がん学会学術集会
  • Place of Presentation: 東京都品川区
  • Year and Date: 2016-12-15
• [Presentation] 発生工学的手法を用いたマーモセット世代短縮技術の開発 (2016)
  • Author(s): 越後貫成美，葛西秀俊，井上弘貴，饗場篤，小倉淳郎.
  • Organizer: 第6回日本マーモセット研究会大会
  • Place of Presentation: 東京都文京区
  • Year and Date: 2016-12-13
• [Presentation] エピジェネティクスと細胞記憶と医学 (2016)
  • Author(s): 佐々木裕之.
  • Organizer: 三和化学研究所Advans研究会2016
  • Place of Presentation: 東京都千代田区
  • Year and Date: 2016-12-11
  • Invited
• [Presentation] マウス着床前初期胚に存在する全能性細胞の評価 (2016)
  • Author(s): 束田裕一.
  • Organizer: さきがけ「エピジェネティクスの制御と生命機能」第1回終了領域研究会
  • Place of Presentation: 福岡県福岡市
  • Year and Date: 2016-12-10
• [Presentation] 全能性細胞で特異的に発現する遺伝子群の機能解析 (2016)
  • Author(s): 中村 肇伸.
  • Organizer: 奈良先端科学技術大学院大学セミナー
  • Place of Presentation: 奈良県、生駒市
  • Year and Date: 2016-12-09
  • Invited
• [Presentation] デザイナーベビー／ゲノム編集の光と影 (2016)
  • Author(s): 伊川正人.
  • Organizer: 大阪大学公開講座
  • Place of Presentation: 大阪府、大阪市
  • Year and Date: 2016-12-07
  • Invited
• [Presentation] Nuclear transfer for the study of developmental epigenetics (2016)
  • Author(s): Ogura A.
  • Organizer: Life Sciences Institute Seminar
  • Place of Presentation: Hangzhou, China
  • Year and Date: 2016-12-06
  • Int'l Joint Research / Invited
• [Presentation] Development of Reproductive Engineering Techniques - Its History and the Present Status. (2016)
  • Author(s): Ogura A.
  • Organizer: Institute of Animal Science Seminar
  • Place of Presentation: Hangzhou, China
  • Year and Date: 2016-12-05
  • Int'l Joint Research / Invited
• [Presentation] CRISPR/Cas9システムを用いたマウスゲノム編集と生殖生物学研究への応用 (2016)
  • Author(s): 伊川正人.
  • Organizer: 日本農芸化学会関西支部 第497回講演会
  • Place of Presentation: 兵庫県、神戸市
  • Year and Date: 2016-12-03
  • Invited
• [Presentation] 顕微授精技術の開発およびその応用研究について (2016)
  • Author(s): 小倉淳郎.
  • Organizer: 第34回生殖工学研究会
  • Place of Presentation: 神奈川県、川崎市
  • Year and Date: 2016-12-03
  • Invited
• [Presentation] EnIGMA-seqによるメチルシトシンとヒドロキシメチルシトシンのゲノムワイド解析 (2016)
  • Author(s): 川崎 佑季、黒田 友紀子、石野 史敏、幸田 尚.
  • Organizer: 第３９回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-12-02
• [Presentation] マウスZscan4は着床前胚および生殖細胞で発現する (2016)
  • Author(s): 石黒 啓一郎 , Manuela Monti , 秋山 智彦 , 木村 寛美 , 近澤 奈々 , 迫田 実希, 佐藤 紗恵子, Redi Carlo, 洪 繁, 洪 実.
  • Organizer: 第３９回日本分子生物学会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-12-02
• [Presentation] アルキル化ピロールイミダゾールポリアミド化合物によるPDL1発現抑制 (2016)
  • Author(s): 服部あすか、平岡桐子、Jaison Lin、篠崎喜脩、養田裕行、井上貴博、渡部隆義、高取敦志、越川信子、永瀬浩喜
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-12-02
• [Presentation] ES細胞に含まれる全能性細胞の可視化とその制御 (2016)
  • Author(s): 古田 明日香、中村 肇伸.
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-12-01
• [Presentation] マウス着床前初期胚が有する全能性の評価 (2016)
  • Author(s): 中島友紀, 束田裕一.
  • Organizer: 日本分子生物学会第39回年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-12-01
• [Presentation] DNA結合小分子PIポリアミドによる選択的DNAメチル化阻害 (2016)
  • Author(s): 依田夏美、篠原憲一、根本哲宏、渡部隆義、永瀬浩喜、喜多和子、金田篤志
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-12-01
• [Presentation] 生殖細胞形成機構の動物種を超えた共通原理と種特異性 (2016)
  • Author(s): 関 由行
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-12-01
• [Presentation] Global landscape and regulatory principles of reprogramming for germ cell specification by mouse pluripotent stem cells. (2016)
  • Author(s): Shirane K, Kurimoto K, Yabuta Y, Yamaji M, Satoh J, Ito S, Watanabe A, Hayashi K, Saitou M, Sasaki H.
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30 – 2016-12-02
• [Presentation] Essential role of Uhrf1 during oocyte growth and preimplantation development. (2016)
  • Author(s): 前之原章司, 鵜木元香, Jafar Sharif, 古関明彦, 藤英博, 大石裕晃, 佐々木裕之.
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30 – 2016-12-02
• [Presentation] 単アレル性発現遺伝子はZfp57によるDNAメチル化依存的及び非依存的な制御を受ける (2016)
  • Author(s): 大石裕晃, 鵜木元香, 一柳健司, 福田渓, 前之原章司, 千葉初音, 佐渡敬, 佐々木裕之.
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30 – 2016-12-02
• [Presentation] Mutations in PLD6 and MILI in mouse oocytes reveal sex-dependent differences in piRNA regulation (2016)
  • Author(s): 樺山由佳, 藤英博, 刀谷在美, 櫻井隆順, 中馬新一郎, 相賀裕美子, 宮川さとみ, 仲野徹, 佐々木裕之.
  • Organizer: 第39回日本分子生物学年会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30 – 2016-12-02
• [Presentation] Role of H3K9 methyltransferase G9a during oogenesis and early embryo development (2016)
  • Author(s): 歐陽允健, 立花誠, 眞貝洋一, 佐々木裕之.
  • Organizer: 第39回日本分子生物学年会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30 – 2016-12-02
• [Presentation] マウスH19 ICRにおけるアリル特異的DNAメチル化制御配列の同定 (2016)
  • Author(s): 松﨑仁美、倉持大地、牛木亜季、谷本啓司.
  • Organizer: 第39回 日本分子生物学会年会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30 – 2016-12-02
• [Presentation] 高血圧応答性エンハンサーによるレニン遺伝子の転写制御 (2016)
  • Author(s): 牛木亜季、松﨑仁美、深水昭吉、谷本啓司.
  • Organizer: 第39回 日本分子生物学会年会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30 – 2016-12-02
• [Presentation] RNA制御を介した精子幹細胞の恒常性維持機構 (2016)
  • Author(s): 相賀裕美子、周智.
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
  • Invited
• [Presentation] 分化多能性を持つヒト胎盤栄養膜幹細胞の樹立 (2016)
  • Author(s): 岡江寛明.
  • Organizer: 第39回分子生物学会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
  • Invited
• [Presentation] H3K9メチル化の動的変動によるほ乳類の発生・分化制御 (2016)
  • Author(s): 立花誠.
  • Organizer: 第39回日本分子生物学会年会シンポジウム「発生・老化・疾患をつかさどるクロマチンイベント」
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-30
  • Invited
• [Presentation] Function of Tet proteins in the maintenance and removal of DNA methylation in CpG islands (2016)
  • Author(s): 山口新平.
  • Organizer: 第39 回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
  • Invited
• [Presentation] Mechanisms of nuclear reprogramming in eggs and oocytes. (2016)
  • Author(s): Miyamoto K.
  • Organizer: King Abdullah University of Science and Technology
  • Place of Presentation: KAUST、Saudi Arabia
  • Year and Date: 2016-11-30
  • Invited
• [Presentation] 卵子の染色体数異常の原因 (2016)
  • Author(s): 北島智也.
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
  • Invited
• [Presentation] 体細胞分裂からの減数分裂への切り替えを制御するMyc/Max/Mgaネットワーク (2016)
  • Author(s): 鈴木 歩、平崎正孝、浅賀正充、浦西洸介、西本正純、奥田晶彦.
  • Organizer: 第39回日本分子生物学会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
• [Presentation] Mbd3/NuRD転写抑制複合体によるES細胞への分化多能性賦与機構の解明 (2016)
  • Author(s): 平崎正孝、鈴木 歩、浦西洸介、浅賀正充、西本正純、奥田晶彦.
  • Organizer: 第39回日本分子生物学会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
• [Presentation] Yapによる細胞の形質転換におけるmiR29を介さない経路の重要性 (2016)
  • Author(s): 西本正純、鈴木 歩、浦西洸介、浅賀正充、平崎正孝、奥田晶彦.
  • Organizer: 第39回日本分子生物学会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
• [Presentation] Selective targeting the PIK3CA mutant sequence by Pyrrole Imidazole polyamide seco-CBI conjugates in cervical cancer (2016)
  • Author(s): Sakthisri Krishnamurthy、高取敦志、養田裕行、平岡桐子、井上貴博、篠崎喜脩、渡部隆義、越川信子、永瀬浩喜
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
• [Presentation] 神経芽腫関連遺伝子Lmo3とHen2は、協調的に機能してマウスにおけるス東証の発症に関与している (2016)
  • Author(s): 磯貝恵理子、奥村和弘、齋藤慈、吉澤康博、宗形春花、伊藤恭子、丹藤創、大平美紀、原口精輝、中川原章、伏木信次、永瀬浩喜、若林雄一
  • Organizer: 第39回日本分子生物学会年会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-30
• [Presentation] Mechanisms of nuclear reprogramming in eggs and oocytes. (2016)
  • Author(s): Miyamoto K.
  • Organizer: New York University Abu Dhabi
  • Place of Presentation: NYU,UAE
  • Year and Date: 2016-11-28
  • Invited
• [Presentation] ゲノム編集技術の進歩と課題 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第11回中部大学ライフサイエンスフォーラム
  • Place of Presentation: 愛知県、春日井市
  • Year and Date: 2016-11-23
  • Invited
• [Presentation] エピジェネティクスと細胞記憶と医学 (2016)
  • Author(s): 佐々木裕之.
  • Organizer: 九州大学医学部第一内科第112回開講記念会
  • Place of Presentation: 福岡県福岡市
  • Year and Date: 2016-11-23
  • Invited
• [Presentation] 始原生殖細胞によるエピゲノムリプログラミング (2016)
  • Author(s): 関 由行
  • Organizer: 第3回北陸エピジェネティクス研究会
  • Place of Presentation: 福井県福井市
  • Year and Date: 2016-11-21
• [Presentation] ゲノム編集を用いた受精関連遺伝子の網羅的機能解析 (2016)
  • Author(s): 伊川正人.
  • Organizer: 新学術領域研究「生殖細胞のエピゲノムダイナミクスとその制御」第４回公開シンポジウム
  • Place of Presentation: 静岡県、三島市
  • Year and Date: 2016-11-17
  • Invited
• [Presentation] Meiosis priming and suppression in male germline stem cells in mice. (2016)
  • Author(s): Hosokawa M, Katanaya A, Hayashi E, Mochizuki A, Numata K, Abe K, Suemori H, Nakatsuji N, Chuma S.
  • Organizer: 新学術領域 生殖細胞のエピゲノムダイナミクスとその制御 第4回公開シンポジウム
  • Place of Presentation: 静岡県、三島市
  • Year and Date: 2016-11-17
• [Presentation] 全能性細胞で高発現するPramef12の機能解析 (2016)
  • Author(s): 中村 肇伸.
  • Organizer: 文部科学省科学研究費補助金 新学術領域研究「生殖細胞のエピゲノムダイナミクスとその制御」第4回公開シンポジウム
  • Place of Presentation: 静岡県三島市
  • Year and Date: 2016-11-16
• [Presentation] 卵母細胞がエラーを起こしやすい原因 (2016)
  • Author(s): 北島智也
  • Organizer: 第4回公開シンポジウム 新学術領域会議「生殖細胞のエピゲノムダイナミクスとその制御」「ステムセルエイジングから解明する疾患原理」
  • Place of Presentation: 静岡県三島市
  • Year and Date: 2016-11-16
• [Presentation] CRISPR/Cas9システムを用いたES細胞のゲノム編集とその応用 (2016)
  • Author(s): 伊川正人.
  • Organizer: BSSR臨床ストレス応答学会
  • Place of Presentation: 山口県、宇部市
  • Year and Date: 2016-11-12
  • Invited
• [Presentation] 卵母細胞がエラーを起こしやすい原因 (2016)
  • Author(s): 北島智也.
  • Organizer: 第37回インターゲノミクスセミナー「染色体分配システム研究の最前線」
  • Place of Presentation: 兵庫県神戸市
  • Year and Date: 2016-11-11
  • Invited
• [Presentation] 理研バイオリソースセンターのマウス胚・精子保存とバックアップ体制およびガラス化保存の可能性について (2016)
  • Author(s): 持田慶司.
  • Organizer: 第3回Cryopreservation Conference 2016
  • Place of Presentation: 愛知県岡崎市
  • Year and Date: 2016-11-11
• [Presentation] Multiple roles for epigenetic regulator UHRF1 in oocyte growth and preimplantation development. (2016)
  • Author(s): Sasaki H.
  • Organizer: The 2nd IMCR Symposium on Endocrine and Metabolism: International Frontiers in Homeostatic Regulation Research
  • Place of Presentation: Gunma , Japan
  • Year and Date: 2016-11-10 – 2016-11-11
  • Int'l Joint Research / Invited
• [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of reproduction (2016)
  • Author(s): Ikawa M.
  • Organizer: 2016 Seoul Symposium on Epigenetics and Chromatin
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-11-09
  • Int'l Joint Research / Invited
• [Presentation] Piwi silences transposon transcription by regulating chromatin compaction. (2016)
  • Author(s): Saito K, Iwasaki YW, Murano K, Ishizu H, Shibuya A, Iyoda Y, Siomi MC, Siomi H.
  • Organizer: Cell Symposia: Functional RNAs
  • Place of Presentation: Guangzhou, China
  • Year and Date: 2016-11-07
  • Int'l Joint Research
• [Presentation] 遺伝子改変マウスが切り拓く配偶子研究の未来と臨床応用への展望 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第61回日本生殖医学会学術講演会・総会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-04
  • Invited
• [Presentation] 体外受精胚における遺伝子発現制御 (2016)
  • Author(s): 幸田尚.
  • Organizer: 第６１回日本生殖医学会学術講演会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-11-03
  • Invited
• [Presentation] 卵子の染色体数異常の原因 (2016)
  • Author(s): 北島智也.
  • Organizer: 第61回日本生殖医学会学術講演会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-11-03
  • Invited
• [Presentation] Multiple functions of the epigenetic regulator UHRF1 in mouse oocytes revealed by trans-omics approaches. (2016)
  • Author(s): Sasaki H.
  • Organizer: The 26th Hot Spring Harbor International Symposium
  • Place of Presentation: Fukuoka, Japan
  • Year and Date: 2016-11-02 – 2016-11-03
  • Int'l Joint Research / Invited
• [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of reproduction (2016)
  • Author(s): Ikawa M.
  • Organizer: The 4th SKLRB Symposium on Reproductive Biology
  • Place of Presentation: Beijing, China
  • Year and Date: 2016-10-27
  • Int'l Joint Research / Invited
• [Presentation] マウス生殖細胞の性分化制御機 (2016)
  • Author(s): 相賀裕美子.
  • Organizer: 熊本大学リエゾンラボ研究会／HIGOプログラム最先端研究セミナー
  • Place of Presentation: 熊本県、熊本市
  • Year and Date: 2016-10-26
  • Invited
• [Presentation] 生殖細胞形成機構の動物種を超えた共通原理と種特異性 (2016)
  • Author(s): 関 由行
  • Organizer: 日本発生生物学会秋季シンポジウム
  • Place of Presentation: 静岡県三島市
  • Year and Date: 2016-10-21
• [Presentation] 前向きコホート研究によるがんの高リスク郡でのアミノ酸変化を伴う多形の解析, (2016)
  • Author(s): 中村洋子、丸喜明、巽康年、奥村和弘、横井佐奈、大平美紀、鍋谷圭宏、深沢賢、片山稔、永瀬浩喜、三上春夫
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-08
• [Presentation] 抗がんピロールイミタゾールポリアミド化合物によるPD-L1発現抑制 (2016)
  • Author(s): 服部あすか、平岡桐子、ジェイソン リン、篠崎喜脩、養田裕行、渡部隆義、高取敦志、越川信子、永瀬浩喜
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-08
• [Presentation] エイドサイトーシスを介したDNA副溝結合性ピロール・イミダゾールポリアミドの腫瘍細胞の取り込み (2016)
  • Author(s): 下里修、松下雅司、内海京寛、中村瑞代、小形武広、桑梅潔、井上貴博、渡部隆義、永瀬浩喜、尾崎俊文
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-08
• [Presentation] Chem-seq : identifying genomic binding sites of a pyrrole-imidazole polyamide by nxt-generation sequencing (2016)
  • Author(s): Lin J, Hiraoka K, Watanabe T, Kuo T, Shinozaki Y, Takatori A, Koshikawa N, Otsuki J, Sugiyama H, Horton P, Nagase H.
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-08
• [Presentation] 放射性標識遺伝子配列特異的アルキル化剤による分子イメージング法の開発 (2016)
  • Author(s): 渡部隆義、井上貴博、平岡桐子、越川信子、高取敦志、永瀬浩喜
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-08
• [Presentation] 小児骨肉腫における肺転移症例に特徴的なゲノム異常 (2016)
  • Author(s): 巽康年、岩田慎太郎、宮冬樹、角田達彦、米本司、鴨田博人、石井猛、永瀬浩喜、大平美紀
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-08
• [Presentation] MYCN遺伝子を標的とした新規DNAアルキル化剤は遺伝子座損傷を介して抗腫瘍効果を発揮 (2016)
  • Author(s): 養田裕行、高取敦志、井上貴博、篠崎喜脩、渡部隆義、越川信子、永瀬浩喜
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-08
• [Presentation] CRISPR/Cas9 mediated genome editing in mice (2016)
  • Author(s): 伊川正人.
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県、横浜市
  • Year and Date: 2016-10-07
  • Invited
• [Presentation] 大腸癌異種移植モデルにおけるピロールイミタゾールポリアミドの腫瘍集積性 (2016)
  • Author(s): 井上貴博、松尾仁似奈、篠崎喜脩、渡部隆義、高取敦志、越川信子、永瀬浩喜
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-07
• [Presentation] mtDNA変異が制御する転移の予測因子としての乳酸トランスポーターMCT4核局在 (2016)
  • Author(s): 越川信子、秋元美穂、植田健、飯笹俊彦、鍋谷圭宏、井内俊彦、永瀬浩喜、竹永啓三
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-07
• [Presentation] がんゲノムの薬剤送達 (2016)
  • Author(s): 永瀬浩喜、高取敦志、渡部隆義、平岡桐子、井上貴博、越川信子、篠崎喜脩、リン ジェーソン、養田裕行、松尾仁以奈、服部あすか
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-07
• [Presentation] 難治性神経芽腫網羅的ゲノム・エピゲノムプロファイル, (2016)
  • Author(s): 大平美紀、巽康年、中村洋子、龍野健二、堤修一、山本尚吾、永江玄太、Claire Renard-Guillet、杉野隆一、永瀬浩喜、上條岳彦、油谷浩幸、中川原章
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-07
• [Presentation] Prmt5 is essential for the maintenance of female reproductive life (2016)
  • Author(s): Suzuki H, Naka T, Suzuki A, Rajkovic A, Kanai-Azuma M.
  • Organizer: 2016 Germ Cell meeting
  • Place of Presentation: NY, USA
  • Year and Date: 2016-10-06
• [Presentation] EWS-FLT1融合遺伝子を標的としたPIポリアミドDNAアルキル化剤によるEwing肉腫の治療戦略 (2016)
  • Author(s): 高取敦志、岩田慎太郎、平岡桐子、クリシュナムーティ サクティシリ、養田裕行、渡部隆義、篠崎喜脩、田中美和、中村卓郎、永瀬浩喜
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-06
• [Presentation] Targeted epigenetic activation of genes by LSD1 inhibitor NCD38 conjugated to Pyrrole Imidazole Polyamide(PIP) (2016)
  • Author(s): Alagarswamy K, Shinohara K, Okabe A, Fukuyo M, Yoda N, Nagase H, Suzuki T, Nemoto T, Kaneda A.
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-06
• [Presentation] 膵腺管自然発生マウスモデルにおけるKRAS変異アルキル化剤の抗腫瘍効果 (2016)
  • Author(s): 松尾仁以奈、井上貴博、平岡桐子、養田裕行、渡部隆義、篠崎喜脩、高取敦志、越川信子、永瀬浩喜
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-06
• [Presentation] Comprehensive genetic analysis for the anticancer activity of a novel alkylating targeting KRA mutation (2016)
  • Author(s): 平岡桐子、Lin Jason、阿久澤夏樹、井上貴博、養田裕行、Krishnamurty Sakthise、渡部隆義、高取敦志、越川信子、尾崎俊文、永瀬浩喜
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-10-06
• [Presentation] Xist/Tsix expression dynamics during mouse peri-implantation development revealed by whole-mount 3D RNA-FISH (2016)
  • Author(s): Shiura H, Abe K.
  • Organizer: X chromosome inactivation : A tribute to Mary Lion
  • Place of Presentation: London, Oxford
  • Year and Date: 2016-10-03 – 2016-10-05
• [Presentation] Roles for epigenetic regulator UHRF1 in imprint maintenance and preimplantation development. (2016)
  • Author(s): Sasaki H.
  • Organizer: Genomic Imprinting, Epigenetics and Physiological Functions, Erice,
  • Place of Presentation: Sicily, Italy
  • Year and Date: 2016-10-02 – 2016-10-07
  • Int'l Joint Research / Invited
• [Presentation] Role for SmcHD1 in the establishment of the proper epigenetic states on the inactive X chromosome. (2016)
  • Author(s): Sakakibara Y, Nagao K, Sasaki H, Blewitt M, Obuse C, Sado T.
  • Organizer: 2016 X-chromosome inactivation: a tribute to Mary Lyon
  • Place of Presentation: London, UK
  • Year and Date: 2016-10-01 – 2016-10-07
• [Presentation] 体細胞クローン胚のDNAメチローム解析による初期化異常パターンの同定 (2016)
  • Author(s): 的場章悟，Shen L, 小倉淳郎, Zhang Y.
  • Organizer: 第109回日本繁殖生物学会
  • Place of Presentation: 神奈川県相模原市
  • Year and Date: 2016-09-30
• [Presentation] 多くのマウス系統で効果的な新しい過排卵誘起法 (2016)
  • Author(s): 長谷川歩未，持田慶司，野田義博，遠藤玉夫，渡辺元，小倉淳郎.
  • Organizer: 第50回日本実験動物技術者協会総会
  • Place of Presentation: 埼玉県川越市
  • Year and Date: 2016-09-30
• [Presentation] ゲノム編集を用いた受精関連遺伝子の網羅的機能解析 (2016)
  • Author(s): 伊川正人.
  • Organizer: 創薬・薬理フォーラム 第24回シンポジウム
  • Place of Presentation: 東京都、渋谷区
  • Year and Date: 2016-09-29
  • Invited
• [Presentation] アリル特異的DNAメチル化（刷り込みメチル化）配列のin vivo再構築 (2016)
  • Author(s): 谷本啓司、松﨑仁美、牛木亜季、倉持大地.
  • Organizer: 第89回 日本生化学会大会
  • Place of Presentation: 岩手県、仙台市
  • Year and Date: 2016-09-25 – 2016-09-27
• [Presentation] Pyrrole Imidazole polyamide conjugates targeting cancer genome. (2016)
  • Author(s): Nagase H, Takatori A, Watanabe T, Koshikawa N, Hiraoka, K, Inoue T, Youda H, Lin J, Shinozaki Y, Sakthisri K, Matsuo N, Hattori A.
  • Organizer: 第89回 日本生化学会 異分野融合によるがん分子標的薬開発シンポジウム
  • Place of Presentation: 青森県、仙台市
  • Year and Date: 2016-09-25 – 2016-09-27
  • Invited
• [Presentation] ES細胞を用いたゲノム編集とキメラ解析 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第89回日本生化学会大会
  • Place of Presentation: 宮城県、仙台市
  • Year and Date: 2016-09-25
  • Invited
• [Presentation] IL-6/STAT3 signaling in adenomyosis. (2016)
  • Author(s): Hirota Y.
  • Organizer: 5th Asian Conference on Endometriosis
  • Place of Presentation: Osaka, Japan
  • Year and Date: 2016-09-23
  • Int'l Joint Research / Invited
• [Presentation] Large cytoplasm predisposes oocytes to chromosome segregation error (2016)
  • Author(s): Kitajima T. S.
  • Organizer: Conference Pigmod and Czechoslovak Biological Society: From reproductive biology to large animal models of human diseases
  • Place of Presentation: Libechov, Czech Republic
  • Year and Date: 2016-09-23
  • Int'l Joint Research / Invited
• [Presentation] 生殖細胞を用いた遺伝資源保存システムの構築 (2016)
  • Author(s): 中島友紀.
  • Organizer: 日本畜産学会サマーキャンプ
  • Place of Presentation: 愛知県岡崎市
  • Year and Date: 2016-09-23
• [Presentation] 実験動物におけるゲノム編集技術について (2016)
  • Author(s): 伊川正人.
  • Organizer: 平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
  • Place of Presentation: 長野県茅、野市
  • Year and Date: 2016-09-17
  • Invited
• [Presentation] Robust induction of primed pluripotency in mammals : Wntinhibition is critical for derivation and maintenance of mouse epiblast stem cells (2016)
  • Author(s): Abe K.
  • Organizer: つくばグローバルサイエンスウィーク2016
  • Place of Presentation: 茨城県、つくば市
  • Year and Date: 2016-09-17
  • Invited
• [Presentation] 体外受精における初期胚の遺伝子発現制御 (2016)
  • Author(s): 幸田尚.
  • Organizer: 第34回日本受精着床学会総会・学術講演会
  • Place of Presentation: 長野県、軽井沢町
  • Year and Date: 2016-09-15
  • Invited
• [Presentation] 抗がん・疾患治療薬剤開発プラットホームの構築 (2016)
  • Author(s): 永瀬浩喜
  • Organizer: 再生システムと疾患・癌エピゲノム公開シンポジウム2016,
  • Place of Presentation: 千葉県千葉市
  • Year and Date: 2016-09-15
• [Presentation] ZFP57による単アレル性遺伝子発現の制御機構 (2016)
  • Author(s): 大石裕晃.
  • Organizer: 第1回エピジェネティック修飾読み手分子の構造と生命機能をつなぐ会
  • Place of Presentation: 福岡県福岡市
  • Year and Date: 2016-09-13
  • Invited
• [Presentation] 卵子形成過程および初期発生におけるUHRF1の役割 (2016)
  • Author(s): 前之原章司.
  • Organizer: 第1回エピジェネティック修飾読み手分子の構造と生命機能をつなぐ会
  • Place of Presentation: 福岡県福岡市
  • Year and Date: 2016-09-13
  • Invited
• [Presentation] マウス受精卵における能動的DNA脱メチル化制御因子の役割 (2016)
  • Author(s): 畑中勇輝, 越後貫成美, 廣瀬美智子, 本多新, 井上貴美子, 松本和也, 小倉淳郎.
  • Organizer: 第109回日本繁殖生物学会
  • Place of Presentation: 神奈川県相模原市
  • Year and Date: 2016-09-13
• [Presentation] マーモセット精子細胞を用いた顕微授精技術の開発 (2016)
  • Author(s): 越後貫成美，葛西秀俊，井上弘貴，饗場篤，小倉淳郎.
  • Organizer: 第109回日本繁殖生物学会
  • Place of Presentation: 神奈川県相模原市
  • Year and Date: 2016-09-13
• [Presentation] Germline Stem(GS)細胞における複数遺伝子の高効率機能解析技術の開発 (2016)
  • Author(s): Suzuki S, Abe K.
  • Organizer: 第109回日本繁殖生物学会大会
  • Place of Presentation: 神奈川県相模原市
  • Year and Date: 2016-09-12 – 2016-09-15
• [Presentation] Oocytes - why so error-prone? (2016)
  • Author(s): 北島智也.
  • Organizer: 国立遺伝学研究所 セミナー
  • Place of Presentation: 静岡県三島市
  • Year and Date: 2016-09-12
  • Invited
• [Presentation] マウス初期胚発生におけるminor ZGAの生物学的な役割 (2016)
  • Author(s): 阿部健一郎、鈴木穣、青木不学.
  • Organizer: 第109回日本繁殖生物学会大会
  • Place of Presentation: 神奈川県相模原市
  • Year and Date: 2016-09-12
• [Presentation] クローン動物がもたらした可能性 (2016)
  • Author(s): 宮本圭.
  • Organizer: 第109回日本繁殖生物学会大会市民公開講座「ノーベル賞の中の繁殖生物学」
  • Place of Presentation: 神奈川県、相模原市
  • Year and Date: 2016-09-11
  • Invited
• [Presentation] CRISPR/Cas9システムを用いた精巣特異的発現遺伝子群の機能解析 (2016)
  • Author(s): 伊川正人.
  • Organizer: 日本ゲノム編集学会
  • Place of Presentation: 広島県、広島市
  • Year and Date: 2016-09-07
  • Invited
• [Presentation] マウス性決定のエピジェネティックな制御機構 (2016)
  • Author(s): 立花誠.
  • Organizer: 日本遺伝学会第88回大会シンポジウム「エピジェネティクスの広がり」
  • Place of Presentation: 静岡県三島市
  • Year and Date: 2016-09-07
  • Invited
• [Presentation] マウス生殖細胞のエピジェネティックリプログラミングにおけるTet1の役割 (2016)
  • Author(s): 山口新平
  • Organizer: 第88回日本遺伝学会大会
  • Place of Presentation: 静岡県三島市
  • Year and Date: 2016-09-07
• [Presentation] マウスのpiRNA産生様式と役割は雌雄で異なる (2016)
  • Author(s): 樺山由佳.
  • Organizer: 第3回転移因子研究会 転移因子と宿主の相互作用による生命機能と進化
  • Place of Presentation: 静岡県三島市
  • Year and Date: 2016-09-06
  • Invited
• [Presentation] Comprehensive study on naive-to-primed stem cell conversion process by integration of single cell transcriptomics and epigenomic analysis (2016)
  • Author(s): Ura H, Bottcher M, Suzuki S, Carninci P, Abe K.
  • Organizer: QBiC Symposium 2016 「Decoding Organisms by Quantitative Cell Profiling」
  • Place of Presentation: Toyonaka, Osaka,
  • Year and Date: 2016-09-05 – 2016-09-07
• [Presentation] 卵成熟と着床異常の疾患モデル (2016)
  • Author(s): 鈴木仁美、金井正美.
  • Organizer: 第57回日本組織細胞化学会総会・学術集会シンポジウム
  • Place of Presentation: 東京都三鷹市
  • Year and Date: 2016-09-04
  • Invited
• [Presentation] 受精前後におけるゲノム再プログラム化の分子機構． (2016)
  • Author(s): 青木不学.
  • Organizer: 第57回組織細胞化学会
  • Place of Presentation: 東京都、三鷹市
  • Year and Date: 2016-09-04
  • Invited
• [Presentation] ゲノム編集技術と実験動物への応用 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第15回教育研究推進センター講演会
  • Place of Presentation: 北海道、旭川市
  • Year and Date: 2016-09-02
  • Invited
• [Presentation] STAT3 promotes uterine regeneration in a mouse model of decellularized uterine matrix transplantation. (2016)
  • Author(s): Hirota Y.
  • Organizer: Gordon Research Conference on Mammalian Reproduction
  • Place of Presentation: Waterville Valley NH, USA
  • Year and Date: 2016-08-24
  • Int'l Joint Research
• [Presentation] The improved culture condition for mouse nuclear transfer embryos enables highly efficient nuclear reprogramming (2016)
  • Author(s): Miyamoto K, Tajima Y, Yoshida K, Tsukaguchi T, Bradshaw C.R, Allen G.E, Mori M, Imazato Y, Jullien J, Matsumoto K, Imai H, Gurdon J.B, Yamada M.
  • Organizer: The 3rd China-Japan-Korea reproduction meeting
  • Place of Presentation: Japan
  • Year and Date: 2016-08-19
  • Int'l Joint Research / Invited
• [Presentation] Regulation of germ cell development by histone demethylation (2016)
  • Author(s): 黒木 俊介, 立花 誠.
  • Organizer: 第1回次世代生命科学の研究会
  • Place of Presentation: 徳島県、徳島市
  • Year and Date: 2016-08-12
• [Presentation] アフリカツメガエル卵母細胞を用いたリプログラミングとクロマチン動構造の解析 (2016)
  • Author(s): 宮本圭.
  • Organizer: 次世代両生類研究会第二回会合
  • Place of Presentation: 愛知県、岡崎市
  • Year and Date: 2016-08-08
  • Invited
• [Presentation] ゲノム編集と生殖生物学研究への応用 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第21回日本病態プロテアーゼ学会学術集会
  • Place of Presentation: 大阪府、豊中市
  • Year and Date: 2016-08-06
  • Invited
• [Presentation] 骨格筋分化におけるクロマチン構造解析-トランスクリプトミクスで理解する骨格筋形成 (2016)
  • Author(s): 原田哲仁.
  • Organizer: 日本農芸化学会中四国支部 支部創立15周年記念 第24回若手シンポジウム
  • Place of Presentation: 山口県下関市
  • Year and Date: 2016-07-28 – 2016-07-29
  • Invited
• [Presentation] ヒト多能性幹細胞のゲノム相同組換え効率の制御メカニズムの探索. (2016)
  • Author(s): 中川史之, 中馬新一郎.
  • Organizer: 新学術領域 生殖細胞のエピゲノムダイナミクスとその制御 ステムセルエイジングから解明する疾患原理 合同若手勉強会.
  • Place of Presentation: 大分県、別府市
  • Year and Date: 2016-07-28
• [Presentation] ES細胞に含まれる全能性細胞の可視化とその制御 (2016)
  • Author(s): 古田 明日香、中村 肇伸.
  • Organizer: 文部科学省科学研究費補助金 新学術領域研究「生殖細胞のエピゲノムダイナミクスとその制御」第4回若手勉強会
  • Place of Presentation: 大分県別府市
  • Year and Date: 2016-07-28
• [Presentation] Visualization tools for epigenomics (2016)
  • Author(s): Abe K.
  • Organizer: The 5th BRC-MARC Mouse Resource Workshop
  • Place of Presentation: 茨城県、つくば市
  • Year and Date: 2016-07-25
• [Presentation] エピジェネティクスと細胞記憶と疾患 (2016)
  • Author(s): 佐々木裕之.
  • Organizer: 第5回日本DOHaD研究会学術集会
  • Place of Presentation: 東京都世田谷区
  • Year and Date: 2016-07-23 – 2016-07-24
  • Invited
• [Presentation] Studies on mouse peri implantation development using developmental mutant and stem cells (2016)
  • Author(s): Abe K.
  • Organizer: 熊本大学リエゾンラボ研究会/HIGOプログラム最先端研究セミナー
  • Place of Presentation: 熊本県熊本市
  • Year and Date: 2016-07-20
  • Invited
• [Presentation] Development of ARTs at RIKEN BRC; 2. Preservation of mouse embryos using a high osmolality vitrification (HOV) method in a deep freezer. (2016)
  • Author(s): Mochida K, Hasegawa A, Ogura A.
  • Organizer: SSR 2016 49th Annual Meeting
  • Place of Presentation: San Diego, USA
  • Year and Date: 2016-07-16 – 2016-07-19
  • Int'l Joint Research
• [Presentation] Development of ARTs at RIKEN BRC; 1. High-yield superovulation with anti-inhibin serum in mouse strains after estrous synchronization (2016)
  • Author(s): Hasegawa A, Mochida K, Inoue H, Ogonuki N, Watanabe G, Ogura A.
  • Organizer: SSR 2016 49th Annual Meeting
  • Place of Presentation: San Diego, USA
  • Year and Date: 2016-07-16 – 2016-07-19
  • Int'l Joint Research
• [Presentation] Histone H3R17me2a mark recruits Tet3 to initiate active DNA demethylation in mouse zygotes (2016)
  • Author(s): Hatanaka Y, Shimizu N, Morita K, Satoh M, Honda A, Hirose M, Kamimura S, Ogonuki N, Nakamura N, Inoue K, Hosoi Y, Nakano T, Matsumoto K, Ogura A.
  • Organizer: Mouse Genetics 2016
  • Place of Presentation: Florida, USA
  • Year and Date: 2016-07-14 – 2016-07-16
  • Int'l Joint Research
• [Presentation] Egg or sperm: which is the default? (2016)
  • Author(s): Saga Y.
  • Organizer: Workshop in Mouse molecular genetics.
  • Place of Presentation: The Allied Genetics Conference sponsored by the Genetics Society of America (GSA). (Orlando, Florida, USA)
  • Year and Date: 2016-07-13 – 2016-07-17
  • Int'l Joint Research / Invited
• [Presentation] Role of a 3’UTR-dependent DAZL suppression in mouse postnatal ovary. (2016)
  • Author(s): Fukuda K, Saga Y.
  • Organizer: Mouse molecular genetics, The Allied Genetics Conference sponsored by the Genetics Society of America (GSA).
  • Place of Presentation: Orlando, Florida, USA)
  • Year and Date: 2016-07-13 – 2016-07-17
  • Int'l Joint Research
• [Presentation] Imprinted DNA methylation status can be reconstituted by combining activity of distinct H19-ICR elements in mice (2016)
  • Author(s): Matsuzaki H, Tanimoto K.
  • Organizer: Mouse Genetics 2016 at The Allied Genetics Conference 2016
  • Place of Presentation: Orlando, Florida, USA
  • Year and Date: 2016-07-13 – 2016-07-17
  • Int'l Joint Research
• [Presentation] 卵母細胞の巨大な細胞サイズの意義 (2016)
  • Author(s): 北島智也
  • Organizer: 第18回京都大学生命科学研究科シンポジウム
  • Place of Presentation: 京都府京都市
  • Year and Date: 2016-07-07
• [Presentation] Developing a novel method to identify chromatin components at transposons using CRISPR/Cas9 system (2016)
  • Author(s): Yamanaka S, Li T, Kawamura T, Kodama T, Siomi H.
  • Organizer: RNA 2016 - The 21st Annual Meeting of the RNA Society and The 18th Annual Meeting of the RNA Society of Japan
  • Place of Presentation: Kyoto,Japan
  • Year and Date: 2016-06-28 – 2016-07-02
• [Presentation] Role of the RNA helicase, Armitage, in the primary piRNA biogenesis pathway (2016)
  • Author(s): Ishizu H.
  • Organizer: The 2016 joint annual meeting of the RNA Society and the RNA Society of Japan
  • Place of Presentation: Kyoto , Japan
  • Year and Date: 2016-06-28
• [Presentation] Effects of oocyte size on chromosome segregation during meiosis (2016)
  • Author(s): Kitajima T. S.
  • Organizer: Meiosis, Gordon Research Conference
  • Place of Presentation: New London, USA
  • Year and Date: 2016-06-27
  • Int'l Joint Research / Invited
• [Presentation] 卵子の染色体数異常の原因 (2016)
  • Author(s): 北島智也.
  • Organizer: 第38回中部生殖医学会学術集会
  • Place of Presentation: 三重県津市
  • Year and Date: 2016-06-18
  • Invited
• [Presentation] CRISPR/Cas9システムを用いたES細胞のゲノム編集とその応用 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第68回日本細胞生物学会大会
  • Place of Presentation: 京都府、京都市
  • Year and Date: 2016-06-17
  • Invited
• [Presentation] Switching from posttranscriptional to transcriptional silencing during male germ-cell development in mice. (2016)
  • Author(s): Ichiyanagi K.
  • Organizer: 1st Korea-Japan International Symposium on Transposable Elements
  • Place of Presentation: Busan, Korea
  • Year and Date: 2016-06-10
  • Int'l Joint Research / Invited
• [Presentation] Nuclear transfer for the study of developmental epigenetics. (2016)
  • Author(s): Ogura A.
  • Organizer: Epigenetic Penetrance of Reproductive Technologies
  • Place of Presentation: Teramo, Italy
  • Year and Date: 2016-06-10
  • Int'l Joint Research / Invited
• [Presentation] 実験動物におけるゲノム編集技術について (2016)
  • Author(s): 伊川正人.
  • Organizer: 第42回国立大学法人動物実験施設協議会総会
  • Place of Presentation: 岐阜県、岐阜市
  • Year and Date: 2016-06-10
  • Invited
• [Presentation] ピロール・イミダゾール・ポリアミドによる遺伝子標的治療薬の開発 (2016)
  • Author(s): 高取敦志、平岡桐子、養田裕行、Krishnamurthy Sakthisri、井上貴博、渡部隆義、越川信子、永瀬浩喜
  • Organizer: 第25回日本癌病態治療研究会
  • Place of Presentation: 千葉市中央区
  • Year and Date: 2016-06-09
• [Presentation] A novel Pyrrole-Imidazole polyamide seco-CBI conjugates targeting PIK3CA gene mutation in cervical cancer (2016)
  • Author(s): Sakthisri K, Takatori A, Yoda H, Hiraoka K, Inoue T, Watanabe T, Koshikawa N, Nagase H.
  • Organizer: 第25回日本癌病態治療研究会
  • Place of Presentation: 千葉市中央区
  • Year and Date: 2016-06-08
• [Presentation] 分子標識薬抗がん化合物PIポリアミドの腫瘍集積 (2016)
  • Author(s): 松尾仁衣奈、井上貴博、平岡桐子、養田裕行、渡部隆義、高取敦志、篠崎喜脩、越川信子、永瀬浩喜
  • Organizer: 第25回日本癌病態治療研究会
  • Place of Presentation: 千葉市中央区
  • Year and Date: 2016-06-08
• [Presentation] 変異型KRAS遺伝子を標的とした新規抗がん剤候補化合物の安全性 (2016)
  • Author(s): 井上貴博、松尾仁似奈、平岡桐子、養田裕行、渡部隆義、篠崎喜脩、越川信子、若菜茂晴、尾崎俊文、永瀬浩喜
  • Organizer: 第25回日本癌病態治療研究会
  • Place of Presentation: 千葉市中央区
  • Year and Date: 2016-06-08
• [Presentation] MYCN遺伝子を標的とした新規抗がん剤の開発 (2016)
  • Author(s): 養田裕行、高取敦志、井上貴博、渡部隆義、越川信子、永瀬浩喜
  • Organizer: 第25回日本癌病態治療研究会
  • Place of Presentation: 千葉市中央区
  • Year and Date: 2016-06-08
• [Presentation] 変異型KRAS遺伝子を標的とした新規アルキル化剤抗腫瘍効果メカニズムの検討 (2016)
  • Author(s): 平岡桐子、Lin Jason、阿久澤夏樹、井上貴博、養田裕行、Krishnamurty Sakthise、渡部隆義、高取敦志、越川信子、尾崎俊文、永瀬浩喜
  • Organizer: 第25回日本癌病態治療研究会
  • Place of Presentation: 千葉市中央区
  • Year and Date: 2016-06-08
• [Presentation] UHRF1の同定からヒストンリジンの水酸化修飾の発見まで (2016)
  • Author(s): 鵜木元香.
  • Organizer: 第16回日本蛋白質科学会年会
  • Place of Presentation: 福岡県、福岡市
  • Year and Date: 2016-06-07 – 2016-06-09
  • Invited
• [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of reproduction (2016)
  • Author(s): 伊川正人.
  • Organizer: 第47回精子研究会
  • Place of Presentation: 秋田県、秋田市
  • Year and Date: 2016-06-04
  • Invited
• [Presentation] 黄体ホルモンによる子宮の胚受容能と着床の調節機構 (2016)
  • Author(s): 廣田泰.
  • Organizer: 第5回プロゲストーゲン研究会
  • Place of Presentation: 東京都港区
  • Year and Date: 2016-06-04
  • Invited
• [Presentation] Role of post transcriptional suppression of Dazl via its 3’UTR in female reproduction. (2016)
  • Author(s): Fukuda K, Saga Y.
  • Organizer: 日本発生生物学会Special Symposium
  • Place of Presentation: Tokyo、Japan
  • Year and Date: 2016-06-02
• [Presentation] ピロールルイミダゾールポリアミドによる大腸がんドライバー遺伝子標的治療薬の開発 (2016)
  • Author(s): 永瀬浩喜、越川信子
  • Organizer: 第20回日本がん分子標的治療学会学術集会
  • Place of Presentation: 大分県別府市
  • Year and Date: 2016-05-31
• [Presentation] ゲノム編集マウス作製と生殖生物学研究への応用 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第8回シグナルネットワーク研究会
  • Place of Presentation: 大阪府、吹田市
  • Year and Date: 2016-05-27
  • Invited
• [Presentation] 成熟マウスの性周期同期化と抗インヒビン血清投与による過排卵誘起法 (2016)
  • Author(s): 持田慶司，長谷川歩未，野田義博，遠藤玉夫，渡辺元，小倉淳郎.
  • Organizer: 第57回日本卵子学会
  • Place of Presentation: 新潟県新潟市
  • Year and Date: 2016-05-26
• [Presentation] 卵子の染色体数異常の原因 (2016)
  • Author(s): 北島智也.
  • Organizer: ナースのためのART医学セミナー2016
  • Place of Presentation: 東京都港区
  • Year and Date: 2016-05-22
  • Invited
• [Presentation] 生殖細胞のエピゲノム：インプリンティングからトランスポゾン制御まで (2016)
  • Author(s): 佐々木裕之.
  • Organizer: 第80回日本生化学会中部支部例会・シンポジウム
  • Place of Presentation: 三重県、津市
  • Year and Date: 2016-05-21
  • Invited
• [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of reproduction (2016)
  • Author(s): Ikawa M.
  • Organizer: 2016 AMMRA meeting
  • Place of Presentation: Kanagawa, Japan
  • Year and Date: 2016-05-20 – 2016-05-21
  • Int'l Joint Research / Invited
• [Presentation] 性周期同期化と抗インヒビン血清による成熟マウスの効率的な過排卵誘起法 (2016)
  • Author(s): 長谷川歩未，持田慶司，野田義博，遠藤玉夫，渡辺元，小倉淳郎.
  • Organizer: 第63回日本実験動物学会総会
  • Place of Presentation: 神奈川県川崎市
  • Year and Date: 2016-05-20
• [Presentation] 精巣の異種異所移植の新しい試み (2016)
  • Author(s): 越後貫成美，山海直，小倉淳郎.
  • Organizer: 第63回日本実験動物学会総会
  • Place of Presentation: 神奈川県川崎市
  • Year and Date: 2016-05-20
• [Presentation] ピロールイミダゾールポリアミドを用いたゲノム・エピゲノム制御への取り組み (2016)
  • Author(s): Lin Jason、養田裕行、平岡桐子、井上貴博、Krishnamurthy Sakthisri、渡部隆義、高取敦志、越川信子、杉山弘、宮野悟、永瀬浩喜
  • Organizer: 第10回日本エピジェネティクス研究会年会
  • Place of Presentation: 大阪府豊中市
  • Year and Date: 2016-05-20
• [Presentation] Tetタンパク質による遺伝子発現調節領域の能動的脱メチル化 (2016)
  • Author(s): 山口新平
  • Organizer: 第10回日本エピジェネティクス研究会年会
  • Place of Presentation: 大阪府豊中市
  • Year and Date: 2016-05-20
• [Presentation] 生殖細胞のエピゲノム：インプリンティングからトランスポゾン制御まで (2016)
  • Author(s): 佐々木裕之.
  • Organizer: 第10回日本エピジェネティクス研究会年会
  • Place of Presentation: 大阪府、豊中市
  • Year and Date: 2016-05-19 – 2016-05-20
  • Invited
• [Presentation] 卵子形成過程および初期胚発生期のDNAメチル化制御におけるUhrf1の重要性 (2016)
  • Author(s): 前之原章司, 鵜木元香, Jafar Sharif, 古関明彦, 藤英博, 大石裕晃, 佐々木裕之.
  • Organizer: 第10回日本エピジェネティクス研究会年会
  • Place of Presentation: 大阪府、豊中市
  • Year and Date: 2016-05-19 – 2016-05-20
• [Presentation] 体外培養始原生殖細胞誘導系のDNAメチル化制御原理の解明 (2016)
  • Author(s): 白根健次郎, 栗本一基, 薮田幸宏, 山路剛史, 渡辺亮, 林克彦, 斎藤通紀, 佐々木裕之.
  • Organizer: 第10回日本エピジェネティクス研究会年会
  • Place of Presentation: 大阪府、豊中市
  • Year and Date: 2016-05-19 – 2016-05-20
• [Presentation] マウスH19 ICR上流配列を介したアリル特異的DNAメチル化の検証 (2016)
  • Author(s): 松﨑仁美、倉持大地、谷本啓司.
  • Organizer: 第10回日本エピジェネティクス研究会年会
  • Place of Presentation: 大阪府、豊中市
  • Year and Date: 2016-05-19 – 2016-05-20
• [Presentation] バイオリソースに資する発生工学技術の開発とその応用研究 (2016)
  • Author(s): 小倉淳郎.
  • Organizer: 第63回日本実験動物学会総会
  • Place of Presentation: 神奈川県、川崎市
  • Year and Date: 2016-05-19
  • Invited
• [Presentation] H3K9脱メチル化酵素Jmjd1aとJmjd1bによる雄性生殖細胞の発生制御 (2016)
  • Author(s): 黒木 俊介, 立花 誠.
  • Organizer: 第10回日本エピジェネティクス研究会年会
  • Place of Presentation: 大阪府、豊中市
  • Year and Date: 2016-05-19
• [Presentation] CRISPR/Cas9など最新のゲノム編集技術を用いた遺伝子改変マウスの作製技術 (2016)
  • Author(s): 伊川正人.
  • Organizer: 第57回日本神経学会学術大会
  • Place of Presentation: 兵庫県、神戸市
  • Year and Date: 2016-05-18
  • Invited
• [Presentation] マウス卵巣におけるPrmt5の機能解析 (2016)
  • Author(s): 鈴木仁美, 仲拓馬, 鈴木敦, Aleksandar Rajkovic, 金井正美.
  • Organizer: 第63回日本実験動物学会総会
  • Place of Presentation: 神奈川県,川崎市
  • Year and Date: 2016-05-18
• [Presentation] Robustinduction of primed pluripotency in mammals : Wntinhibition is critical for derivation and maintenance of mouse epiblast stem cells (2016)
  • Author(s): Abe K, Kondo M, Sugimoto M.
  • Organizer: INASCON(International Scientific Conference)2016
  • Place of Presentation: Kelantan, Malaysia.
  • Year and Date: 2016-05-16 – 2016-05-17
  • Int'l Joint Research / Invited
• [Presentation] Switching from post-transcriptional to transcriptional silencing of retrotransposons during male germ-cell development. (2016)
  • Author(s): Sasaki H, Inoue K, Fukuda K, Glinka M, Ichiyanagi K.
  • Organizer: The 4th Cold Spring Harbor Asia Conference on Chromatin, Epigenetics and Transcription
  • Place of Presentation: Suzhou, China
  • Year and Date: 2016-05-09 – 2016-05-13
  • Int'l Joint Research / Invited
• [Presentation] Essential role of Uhrf1 during oocyte growth and preimplantation development. (2016)
  • Author(s): Maenohara S, Unoki M, Sharif J, Koseki H, Toh H, Ohishi H, Sasaki H.
  • Organizer: The 4th Cold Spring Harbor Asia conference on Chromatin, Epigenetics and Transcription
  • Place of Presentation: Suzhou, China
  • Year and Date: 2016-05-09 – 2016-05-13
  • Int'l Joint Research
• [Presentation] Global landscape and regulatory principles of DNA methylation reprogramming for germ cell specification by mouse pluripotent stem cells. (2016)
  • Author(s): Shirane K, Kurimoto K, Yabuta Y, Yamaji M, Watanabe A, Hayashi K, Saitou M, Sasaki H.
  • Organizer: The 4th Cold Spring Harbor Asia Conference on Chromatin, Epigenetics and Transcription
  • Place of Presentation: Suzhou, China
  • Year and Date: 2016-05-09 – 2016-05-13
  • Int'l Joint Research
• [Presentation] Mutations in PLD6 and MILI in mouse oocytes reveal sex-dependent differences in piRNA regulation. (2016)
  • Author(s): Kabayama Y, Toh H, Katanaya A, Sakurai T, Watanabe T, Chuma S, Saga Y, Kuramochi-Miyagawa S, Nakano T, Sasaki H.
  • Organizer: The 4th Cold Spring Harbor Asia Conference on Chromatin, Epigenetics and Transcription
  • Place of Presentation: Suzhou, China
  • Year and Date: 2016-05-09 – 2016-05-13
  • Int'l Joint Research
• [Presentation] Detection of somatic mutations associated with pulmonary metastasis of osteosarooma by whole exome sequencing (2016)
  • Author(s): Iwata S, Tatsumi Y, Yonemoto T, Komoda H, shii T, Nagase H, Ohira M.
  • Organizer: American Association for Cancer Research Annual Meeting
  • Place of Presentation: アメリカ合衆国・ルイジアナ州
  • Year and Date: 2016-04-16 – 2016-04-20
• [Book] バイオテクノロジー入門 (2016)
  • Author(s): 高畑京也、蔡晃植、齊藤修、今村綾、宇佐美昭二、尾山廣、数岡孝幸、河内浩行、佐々壽浩、髙村岳樹、田中直子、永井信夫、仲亀誠司、中村肇伸、徳田宏晴、殿山泰弘、濱田博喜、室伏誠、若生豊.
  • Total Pages: 168
  • Publisher: 建泉社
• [Book] 実験医学増刊 Vol.34 No.20 All Aboutゲノム編集 マウスでのゲノム編集 (2016)
  • Author(s): 野田大地，大字亜沙美，伊川正人.
  • Total Pages: 234
  • Publisher: 羊土社
• [Book] 実験医学別冊 マウス表現型解析スタンダード 生殖不全の表現型解析 (2016)
  • Author(s): 藤原祥高，佐藤裕公，伊川正人.
  • Total Pages: 351
  • Publisher: 羊土社
• [Book] 実験医学別冊 マウス表現型解析スタンダード ゲノム編集技術を使った遺伝子改変マウスの作製 (2016)
  • Author(s): 野田大地，大字亜沙美，伊川正人.
  • Total Pages: 351
  • Publisher: 羊土社
• [Book] 医学のあゆみ Vol. 258 No. 9 精子カルシニューリンが受精能力に必要 (2016)
  • Author(s): 宮田治彦, 伊川正人.
  • Total Pages: 282
  • Publisher: 医歯薬出版株式会社
• [Book] 臨床免疫・アレルギー科 Vol. 66 No. 1 精子カルシニューリンはオスの生殖能に必須である (2016)
  • Author(s): 宮田治彦, 伊川正人.
  • Total Pages: 94
  • Publisher: 科学評論社
• [Book] HORMONE FRONTIER IN GYNECOLOGY ゲノム編集・遺伝子改変技術と生殖医学 (2016)
  • Author(s): 伊川正人.
  • Total Pages: 84
  • Publisher: メディカルレビュー社
• [Book] Japanese Scientists in Science 2015 マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる (2016)
  • Author(s): 宮田治彦，伊川正人.
  • Total Pages: 80
  • Publisher: American Association for the Advancement of Science(AAAS)
• [Book] マウス表現型解析スタンダード 顕微授精・核移植クローン技術（配偶子・体細胞からの産子作出） (2016)
  • Author(s): 小倉淳郎，的場章悟.
  • Total Pages: 350
  • Publisher: 羊土社
• [Book] 実験医学 Vol.34 No.8 次世代の核移植技術の利用に向けて (2016)
  • Author(s): 宮本 圭.
  • Total Pages: 141
  • Publisher: 羊土社
• [Patent(Industrial Property Rights)] 哺乳動物核移植胚の発生率向上法 (2017)
  • Inventor(s): 宮本圭、岩元正樹.
  • Industrial Property Rights Holder: 学校法人近畿大学、プライムテック株式会社
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2017―15891
  • Filing Date: 2017-01-31
• [Patent(Industrial Property Rights)] DNA結合タンパク質の結合領域の近傍に所望のDNA断片を挿入する方法 (2016)
  • Inventor(s): 大川恭行、原田哲仁、胡桃坂仁志、木村宏、半田哲也佐藤優子林陽子.
  • Industrial Property Rights Holder: 国立大学法人九州大学、国立大学法人東京工業大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願2016-167967
  • Filing Date: 2016-08-30
• [Funded Workshop] CDB Symposium 2017“Towards Understanding Human Development, Heredity, and Evolution” (2017)
  • Place of Presentation: 理化学研究所
  • Year and Date: 2017-03-27 – 2017-03-29
• [Funded Workshop] RIKEN Epigenetics 2017 "Recent advances in Epigenetic Engineering" (2017)
  • Place of Presentation: 理化学研究所
  • Year and Date: 2017-02-16 – 2017-02-17
• [Funded Workshop] ヒューマンフロンティアサイエンスプログラムHFSP（キックオフシンポジウム） 「Nuclear actin in the regulation of transcription and nuclear structure.」 (2017)
  • Place of Presentation: 近畿大学生物理工学部
  • Year and Date: 2017-01-26 – 2017-01-26
• [Funded Workshop] 第１4回RCGMフロンティア国際シンポジウム (2016)
  • Place of Presentation: 埼玉医科大学
  • Year and Date: 2016-11-11 – 2016-11-12
• [Funded Workshop] Notch signaling meeting（国立遺伝学研究所研究会） (2016)
  • Place of Presentation: 国立遺伝学研究所
  • Year and Date: 2016-10-05 – 2016-10-06
• [Funded Workshop] 日本遺伝学会第88回大会 シンポジウム「エピジェネティクスの広がり」 (2016)
  • Place of Presentation: 日本大学
  • Year and Date: 2016-09-07 – 2016-09-07
• [Funded Workshop] 領域若手勉強会2016「生殖細胞のエピゲノムダイナミクスとその制御/ステムセルエイジングから解明する疾患原理」 (2016)
  • Place of Presentation: 別府亀の井ホテル
  • Year and Date: 2016-07-27 – 2016-07-29
• [Funded Workshop] Mouse molecular genetics (co-organizer), The Allied Genetics Conference sponsored by the Genetics Society of America (GSA) (2016)
  • Place of Presentation: GSA
  • Year and Date: 2016-07-13 – 2016-07-17