2018 Fiscal Year Annual Research Report
Multidisciplinary computational anatomy and its application to highly intelligent diagnosis and therapy
Project Area | Multidisciplinary computational anatomy and its application to highly intelligent diagnosis and therapy |
Project/Area Number |
26108001
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Research Institution | Kyushu University |
Principal Investigator |
橋爪 誠 九州大学, 先端医療イノベーションセンター, 名誉教授 (90198664)
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Co-Investigator(Kenkyū-buntansha) |
目加田 慶人 中京大学, 工学部, 教授 (00282377)
藤田 廣志 岐阜大学, 工学部, 特任教授・名誉教授 (10124033)
井宮 淳 千葉大学, 統合情報センター, 教授 (10176505)
森 健策 名古屋大学, 情報学研究科, 教授 (10293664)
増谷 佳孝 広島市立大学, 情報科学研究科, 教授 (20345193)
正宗 英津子 (小林英津子) 東京女子医科大学, 医学部, 准教授 (20345268)
鈴木 直樹 東京慈恵会医科大学, 医学部, 教授 (40147327)
縄野 繁 国際医療福祉大学, 医学部, 教授 (40156005)
本谷 秀堅 名古屋工業大学, 工学(系)研究科(研究院), 教授 (60282688)
佐藤 嘉伸 奈良先端科学技術大学院大学, 先端科学技術研究科, 教授 (70243219)
仁木 登 徳島大学, 大学院社会産業理工学研究部(理工学域), 非常勤講師 (80116847)
清水 昭伸 東京農工大学, 工学(系)研究科(研究院), 教授 (80262880)
木戸 尚治 山口大学, 大学院創成科学研究科, 教授 (90314814)
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Project Period (FY) |
2014-07-10 – 2019-03-31
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Keywords | 多元計算解剖学 / 医用画像 / 医用イメージング |
Outline of Annual Research Achievements |
本当該年度も引き続き、総括班主導で領域全体の管理運営に当たると同時に、昨年度までに総括班の下に構築した各WGが各計画研究班および公募研究班の有機的な連携を支援した。DB構築支援WG(清水、縄野、小田): 昨年度に続き、臨床系研究班から得られた人およびマウスの病理組織のデータベースをさらに拡充し、各研究班がアクセス可能なインフラ整備をひきつづきすすめた。学理構築支援WG(リーダー:増谷、数理部門:本谷、増谷、井宮、臨床部門:木戸,菅野、縄野、大内田): 昨年度に続き、必要かつ重要な論文リストを作成し、各計画班に共有可能にした。融合支援WG(森、小林):本当該年度は、巨大ポスターなど作成をすすめ、領域全体の成果を融合した形での発表を行った。渉外(広報)WG(森、二木、目加田、植村): 本当該年度も昨年度までと同様に業績をwebに掲載し、Newsletterを発行した。さらに領域内外に広く活動内容の広報を行った。人材育成WG(佐藤、鈴木): 昨年に引き続き、各計画班で著名な研究者を国内外から招聘し領域内研究者向けのセミナーを開催した。また、昨年度と同様に若手が自主的に形成したsubグループとして若手研究および学生向けの研究コンテツの作成を行った。国際連携支援WGを強化するため、総括班内に設置された国際活動支援班としては、本年度は昨年度に引き続き、各国研究機関との連携や国際学会におけるセッション開催等、国内外連携活動を支援した。臨床支援WG(藤田、増谷、大内田):各計画班と密に連絡をとり、重複の有無、連携関係の統合整備、各領域における専門用語の統一などを引き続き行い、医工連携研究の橋渡しを強化した。
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Research Progress Status |
平成30年度が最終年度であるため、記入しない。
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Strategy for Future Research Activity |
平成30年度が最終年度であるため、記入しない。
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Research Products
(244 results)
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[Journal Article] Colorectal endoscopic submucosal dissection using novel articulating devices: a comparative study in a live porcine model2019
Author(s)
Okamoto Y, Nakadate R, Nakamura S, Arata J, Oguri S, Moriyama T, Esaki M, Iwasa T, Ohuchida K, Akahoshi T, Ikeda T, Kitazono T, Hashizume M
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Journal Title
Surg Endosc
Volume: 33(2)
Pages: 651-657
DOI
Peer Reviewed
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[Journal Article] Adipose tissue-derived stromal cells are sources of cancer-associated fibroblasts and enhance tumor progression by dense collagen matrix2019
Author(s)
Okumura T, Ohuchida K, Kibe S, Iwamoto C, Ando Y, Takesue S, Nakayama H, Abe T, Endo S, Koikawa K, Sada M, Horioka K, Mochidome N, Arita M, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Mizumoto K, Oda Y, Hashizume M, Nakamura M
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Journal Title
Int J Cancer
Volume: 144(6)
Pages: 1401-1413
DOI
Peer Reviewed
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[Journal Article] Pulmonary blood vessels extraction from dual-energy CT images using a synchrotron radiation micro-CT2019
Author(s)
K. Saito, S. Ohnishi, S. Fuketa, Y. Kawata, N. Niki, K. Umetani, H. Sakai, Y. Nakano, T. Okamoto, H. Itoh
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Journal Title
Proc. SPIE 10953, SPIE Medical Imaging 2019
Volume: -
Pages: 109530G
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] Computer-aided CT image features improving the malignant risk prediction in pulmonary nodules suspicious for lung cancer2019
Author(s)
Y. Kawata, T. Kageyama, N. Niki, M. Kusumoto, H. Ohmatsu, K. Aokage, G. Ishii, Y. Matsumoto, T. Tsuchida, K. Eguchi, M. Kaneko
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Journal Title
Proc. SPIE 10950, SPIE Medical Imaging 2019
Volume: -
Pages: 109501J
DOI
Peer Reviewed
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[Journal Article] Radiomics nomogram for predicting the malignant potential of gastrointestinal stromal tumours preoperatively2019
Author(s)
Tao Chen, Zhenyuan Ning, Lili Xu, Xingyu Feng, Shuai Han, Holger R. Roth, Wei Xiong, Xixi Zhao, Yanfeng Hu, Hao Liu, Jiang Yu, Yu Zhang, Yong Li, Yikai Xu, Kensaku Mori, Guoxin Li
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Journal Title
European radiology
Volume: 29
Pages: 1074-1082
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] Influenza B associated paediatric acute respiratory infection hospitalization in central vietnam2018
Author(s)
Yoshihara K, Le MN, Toizumi M, Nguyen HA, Vo HM, Odagiri T, Fujisaki S, Ariyoshi K, Moriuchi H, Hashizume M, Dang DA, Yoshida LM
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Journal Title
Influenza Other Respir Viruses
Volume: -
Pages: -
DOI
Peer Reviewed
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[Journal Article] Temperature-related mortality impacts under and beyond Paris Agreement climate change scenarios2018
Author(s)
Vicedo-Cabrera AM, Guo Y, Sera F, Huber V, Schleussner CF, Mitchell D, Tong S, de Sousa Zanotti Stagliorio Coelho M, Saldiva PHN, Lavigne E, Correa PM, Ortega NV, Kan H, Osorio S, Kysel? J, Urban A, Jaakkola JJK, Ryti NRI, Pascal M, Goodman PG, Zeka A, Michelozzi P, Scortichini M, Hashizume M, et all
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Journal Title
Clim Change
Volume: 150(3-4)
Pages: 391-402
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] Seasonality of respiratory viruses causing hospitalizations for acute respiratory infections in children in Nha Trang, Vietnam2018
Author(s)
Althouse BM, Flasche S, Minh LN, Thiem VD, Hashizume M, Ariyoshi K, Anh DD, Rodgers GL, Klugman KP, Hu H, Yoshida LM
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Journal Title
Int J Infect Dis
Volume: 75
Pages: 18-25
DOI
Peer Reviewed
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[Journal Article] A case of pheochromocytoma with a marked decrease in catecholamine levels after rupture in which a good outcome was achieved by elective surgery2018
Author(s)
Murai N, Azami T, Iida T, Mikura K, Imai H, Kaji M, Hashizume M, Kigawa Y, Koizumi G, Tadokoro R, Endo K, Iizaka T, Saiki R, Otsuka F, Norose T, Yamagishi M, Kurokawa I, Oike N, Sasaki H, Nagasaka S
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Journal Title
Endocr J
Volume: 65(11)
Pages: 1093-1099
DOI
Peer Reviewed
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[Journal Article] Quantifying excess deaths related to heatwaves under climate change scenarios: A multicountry time series modelling study2018
Author(s)
Guo Y, Gasparrini A, Li S, Sera F, Vicedo-Cabrera AM, de Sousa Zanotti Stagliorio Coelho M, Saldiva PHN, Lavigne E, Tawatsupa B, Punnasiri K, Overcenco A, Correa PM, Ortega NV, Kan H, Osorio S, Jaakkola JJK, Ryti NRI, Goodman PG, Zeka A, Michelozzi P, Scortichini M, Hashizume M, et all
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Journal Title
PLoS Med
Volume: 15(7)
Pages: e1002629
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] Visualizing Energy Charge in Breast Carcinoma Tissues by MALDI Mass-spectrometry Imaging Profiles of Low-molecular-weight Metabolites2018
Author(s)
Torata N, Kubo M, Miura D, Ohuchida K, Mizuuchi Y, Fujimura Y, Hayakawa E, Kai M, Oda Y, Mizumoto K, Hashizume M, Nakamura M
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Journal Title
Anticancer Res
Volume: 38(7)
Pages: 4267-4272
DOI
Peer Reviewed
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[Journal Article] The influence of aging on the methylation status of brain-derived neurotrophic factor gene in blood2018
Author(s)
Ihara K, Fuchikami M, Hashizume M, Okada S, Kawai H, Obuchi S, Hirano H, Fujiwara Y, Hachisu M, Hongyong K, Morinobu S
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Journal Title
Int J Geriatr Psychiatry
Volume: 33(10)
Pages: 1312-1318
DOI
Peer Reviewed
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[Journal Article] Changing Susceptibility to Non-Optimum Temperatures in Japan, 1972-2012: The Role of Climate, Demographic, and Socioeconomic Factors2018
Author(s)
Chung Y, Yang D, Gasparrini A, Vicedo-Cabrera AM, Fook Sheng Ng C, Kim Y, Honda Y, Hashizume M
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Journal Title
Environ Health Perspect
Volume: 126(5)
Pages: 57002
DOI
Peer Reviewed
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[Journal Article] A new robotic-assisted flexible endoscope with single-hand control: endoscopic submucosal dissection in the ex vivo porcine stomach2018
Author(s)
Iwasa T, Nakadate R, Onogi S, Okamoto Y, Arata J, Oguri S, Ogino H, Ihara E, Ohuchida K, Akahoshi T, Ikeda T, Ogawa Y, Hashizume M
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Journal Title
Surg Endosc
Volume: 32(7)
Pages: 3386-3392
DOI
Peer Reviewed
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[Journal Article] The non-linear and lagged short-term relationship between rainfall and leptospirosis and the intermediate role of floods in the Philippines2018
Author(s)
Matsushita N, Ng CFS, Kim Y, Suzuki M, Saito N, Ariyoshi K, Salva EP, Dimaano EM, Villarama JB, Go WS, Hashizume M
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Journal Title
PLoS Negl Trop Dis
Volume: 12(4)
Pages: e0006331
DOI
Peer Reviewed
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[Journal Article] Basement membrane destruction by pancreatic stellate cells leads to local invasion in pancreatic ductal adenocarcinoma2018
Author(s)
Koikawa K, Ohuchida K, Ando Y, Kibe S, Nakayama H, Takesue S, Endo S, Abe T, Okumura T, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M
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Journal Title
Cancer Lett
Volume: 425
Pages: -
DOI
Peer Reviewed
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[Journal Article] Laparoscopic ultrasound manipulator with a spring-based elastic mechanism2018
Author(s)
Arata J, Fukami K, Oguri S, Onogi S, Ikeda T, Nakadate R, Sakaguchi M, Akahoshi T, Harada K, Mitsuishi M, Hashizume M
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Journal Title
Int J Comput Assist Radiol Surg
Volume: 13(7)
Pages: 1063-1072
DOI
Peer Reviewed
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[Journal Article] A multi-country analysis on potential adaptive mechanisms to cold and heat in a changing climate2018
Author(s)
Vicedo-Cabrera AM, Sera F, Guo Y, Chung Y, Arbuthnott K, Tong S, Tobias A, Lavigne E, de Sousa Zanotti Stagliorio Coelho M, Hilario Nascimento Saldiva P, Goodman PG, Zeka A, Hashizume M, Honda Y, Kim H, Ragettli MS, R??sli M, Zanobetti A, Schwartz J, Armstrong B, Gasparrini A
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Journal Title
Environ Int
Volume: 111
Pages: 239-246
DOI
Peer Reviewed / Int'l Joint Research
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[Journal Article] Ultrasensitive MRI detection of spontaneous pancreatic tumors with nanocage-based targeted contrast agent2018
Author(s)
Kawano T, Murata M, Kang JH, Piao JS, Narahara S, Hyodo F, Hamano N, Guo J, Oguri S, Ohuchida K, Hashizume M
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Journal Title
Biomaterials
Volume: 152
Pages: 37-46
DOI
Peer Reviewed
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[Journal Article] Mortality burden of diurnal temperature range and its temporal changes: A multi-country study2018
Author(s)
Lee W, Bell ML, Gasparrini A, Armstrong BG, Sera F, Hwang S, Lavigne E, Zanobetti A, Coelho MSZS, Saldiva PHN, Osorio S, Tobias A, Zeka A, Goodman PG, Forsberg B, Rockl?v J, Hashizume M, Honda Y, Guo YL, Seposo X, Van Dung D, Dang TN, Tong S, Guo Y, Kim H
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Journal Title
Environ Int
Volume: 110
Pages: 123-130
DOI
Peer Reviewed
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[Journal Article] Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo1802018
Author(s)
Koikawa K, Ohuchida K, Takesue S, Ando Y, Kibe S, Nakayama H, Endo S, Abe T, Okumura T, Horioka K, Sada M, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Ohuchida R, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M
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Journal Title
Cancer Lett
Volume: 412
Pages: 143-154
DOI
Peer Reviewed
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[Journal Article] Analysis of lipid raft molecules in the living brain slices2018
Author(s)
Kotani N, Nakano T, Ida Y, Ito R, Hashizume M, Yamaguchi A, Seo M, Araki T, Hojo Y, Honke K, Murakoshi T
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Journal Title
Neurochem Int
Volume: 119
Pages: 140-150
DOI
Peer Reviewed
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[Journal Article] Differences of tumor microenvironment between stage I lepidic-positive and lepidic-negative lung adenocarcinomas.2018
Author(s)
Katsumata S, Aokage K, Miyoshi T, Tane K, Nakamura H, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Hayashi R, Tsuboi M, Ishii G.
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Journal Title
J Thorac Cardiovasc Surg
Volume: 156(4)
Pages: 1679-1688
DOI
Peer Reviewed
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[Journal Article] The ratio of cancer cells to stroma within the invasive area is a histologic prognostic parameter of lung adenocarcinoma.2018
Author(s)
Ichikawa T, Aokage K, Sugano M, Miyoshi T, Kojima M, Fujii S, Kuwata T, Ochiai A, Suzuki K, Tsuboi M, Ishii G.
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Journal Title
Lung Cancer
Volume: 118
Pages: 30-35
DOI
Peer Reviewed
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[Journal Article] Sub-solid nodule detectability in seven observers of seventy-nine clinical cases: comparison between ultra-low-dose chest digital tomosynthesis with iterative reconstruction and chest radiography by receiver-operating characteristics analysis.2018
Author(s)
Nagatani Y, Takahashi M, Ikeda M, Nitta N, Miyata K, Hanaoka J, Nakano Y, Matsuo S, Hamada Y, Sonoda A, Otani H, Ushio N, Ohta S, Murakami Y, Kaneko C, Inoue A, Kida T, Murata K.
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Journal Title
European Journal of Radiology
Volume: 107
Pages: 166-174
DOI
Peer Reviewed
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[Journal Article] Genome-wide association study to identify a new susceptibility locus for central serous chorioretinopathy in the Japanese population.2018
Author(s)
Miki A, Sakurada Y, Tanaka K, Semba K, Mitamura Y, Yuzawa M, Tajima A, Nakatochi M, Yamamoto K, Matsuo K, Imoto I, Honda S.
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Journal Title
Invest Ophthalmol Vis Sci.
Volume: 59(13)
Pages: 5542-5547
Peer Reviewed
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[Journal Article] Application of three-dimensional print in minor hepatectomy following liver partition between anterior and posterior sectors2018
Author(s)
Tsuyoshi Igami, Yoshihiko Nakamura, Masahiro Oda, Hiroshi Tanaka, Motoi Nojiri, Tomoki Ebata, Yukihiro Yokoyama, Gen Sugawara, Takashi Mizuno, Junpei Yamaguchi, Kensaku Mori, Masato Nagino
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Journal Title
ANZ Journal of Surgery
Volume: 88
Pages: 882-885
DOI
Peer Reviewed
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[Journal Article] Real-Time Use of Artificial Intelligence in Identification of Diminutive Polyps During Colonoscopy: A Prospective Study2018
Author(s)
Yuichi Mori, Shin-ei Kudo, Masashi Misawa, Yutaka Saito, Hiroaki Ikematsu, Yasuharu Maeda, Kenichi Takeda, Hiroki Nakamura, Katsuro Ichimasa, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Fumio Ishida, Haruhiro Inoue, Hayato Itoh, Masahiro Oda, Kensaku Mori, et all
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Journal Title
Annals of Internal Medicine
Volume: 169
Pages: 357-366
DOI
Peer Reviewed
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[Journal Article] Artificial Intelligence-Assisted Polyp Detection for Colonoscopy: Initial Experience2018
Author(s)
Masashi Misawa, Shin-ei Kudo, Yuichi Mori, Kenichi Takeda, Katsuro Ichimasa, Hiroki Nakamura, Yusuke Yagawa, Naoya Toyoshima, Noriyuki Ogata, Toyoki Kudo, Tomokazu Hisayuki, Takemasa Hayashi, Kunihiko Wakamura, Toshiyuki Baba, Fumio Ishida, Hayato Ito, Roth Holger, Kensaku Mori, et all
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Journal Title
Gastroenterology
Volume: 154
Pages: 2027-2029
DOI
Peer Reviewed
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[Presentation] 放射光CT画像による肺3次元ミクロ構造の血管系解析2019
Author(s)
泓田 彰汰, 斉藤 くるみ, 大西 悟, 河田 佳樹, 仁木 登, 梅谷 啓二, 阪井 宏彰, 中野 恭幸, 岡本 俊宏, 伊藤 春海,
Organizer
電子情報通信学会技術研究報告医用画像
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[Presentation] Scanning, registration, and fiber estimation of rabbit hearts using micro-focus and refraction-contrast x-ray CT2019
Author(s)
Hirohisa Oda, Holger R. Roth, Takaaki Sugino, Naoki Sunaguchi, Noriko Usami, Masahiro Oda, Daisuke Shimao, Shu Ichihara, Tetsuya Yuasa, Masami Ando, Toshiaki Akita, Yuji Narita, Kensaku Mori
Organizer
SPIE
Int'l Joint Research
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[Presentation] Multiclass vertebral fracture classification using probability SVM with multi-feature selection2019
Author(s)
Liyuan Zhang, Huamin Yang, Jiashi Zhao, Weili Shi, Yu Miao, Fei He, Wei He, Yanfang Li, Ke Zhang, Kensaku Mori, Zhengang Jiang
Organizer
SPIE
Int'l Joint Research
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[Presentation] 胸部CT画像・診療情報による肺結節の悪性リスクモデルの構築2018
Author(s)
景山 健, 河田 佳樹, 鈴木 秀宣, 仁木 登, 楠本 昌彦, 大松 広伸, 青景 圭樹, 土田 敬明, 松元 裕司, 江口 研二, 金子 昌弘
Organizer
第26回日本CT検診学会学術集会
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[Presentation] 3D High-Resolution Microstructure Imaging of the Heart2018
Author(s)
Hirohisa Oda, Holger R. Roth, Naoki Sunaguchi, Tetsuya Yuasa, Toshiaki Akita, Kensaku Mori, Daisuke Shimao, Shu Ichihara, Masami Ando, Noriko Usami, Masahiro Oda, Yuji Narita
Organizer
RSNA
Int'l Joint Research
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[Presentation] Attention U-Net: Learning Where to Look for the Pancreas2018
Author(s)
Ozan Oktay, Jo Schlemper, Loic Le Folgoc, Matthew Lee, Mattias Heinrich, Kazunari Misawa, Kensaku Mori, Steven McDonagh, Nils Y. Hammerla, Bernhard Kainz, Ben Glocker, Daniel Rueckert
Organizer
MIDL
Int'l Joint Research
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[Presentation] Micro-focus X-ray CT of the heart: A comparison with X-ray refraction-contrast CT2018
Author(s)
Hirohisa Oda, Holger R. Roth, Naoki Sunaguchi, Daisuke Shimao, Takaaki Sugino, Masahiro Oda, Toshiaki Akita, Yuji Narita, Shu Ichihara, Tetsuya Yuasa, Masami Ando, Kensaku Mori
Organizer
CARS
Int'l Joint Research
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[Presentation] イレウス診断支援システムにおける閉塞部位の誤検出修正及び改善ツールの構築2018
Author(s)
西尾 光平, 小田 紘久, 千馬 耕亮, 北坂 孝幸, Holger R. Roth, 伊東 隼人, 林 雄一郎, 小田 昌宏, 檜 顕成, 内田 広夫, 森 健策
Organizer
第27回日本コンピュータ外科学会大会
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[Presentation] U-Netを用いた腹腔鏡動画像における出血領域検出に関する検討2018
Author(s)
小澤 卓也, 小田 紘久, 伊東 隼人, 北坂 孝幸, Holger R. Roth, 小田 昌宏, 林 雄一郎, 三澤 一成, 伊藤 雅昭, 竹下 修由 , 森 健策
Organizer
第27回日本コンピュータ外科学会大会
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[Presentation] ウサギ心臓の屈折CT像における線維配向の可視化ならびに評価2018
Author(s)
小田 紘久, Holger R. Roth, 砂口 尚輝, 宇佐美 紀子, 小田 昌宏 , 島雄 大介, 市原 周, 湯浅 哲也, 安藤 正海, 秋田 利明, 成田 裕司, 森 健策
Organizer
第37回日本医用画像工学会大会 (JAMIT2018)
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[Presentation] 機械学習による内視鏡動画インスタンスセグメンテーションのための手動アノテーションツールの開発2018
Author(s)
小澤 卓也, 小田 紘久, 伊東 隼人, 北坂 孝幸, Holger R. Roth, 小田 昌宏, 林 雄一郎, 三澤 一成, 伊藤 雅昭, 竹下 修由, 森 健策
Organizer
第37回日本医用画像工学会大会 (JAMIT2018)
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