2018 Fiscal Year Final Research Report

Oxygen biology: a new criterion for integrated understanding of life

Administrative Group

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Project Area	Oxygen biology: a new criterion for integrated understanding of life
Project/Area Number	26111001
Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Allocation Type	Single-year Grants
Review Section	Biological Sciences
Research Institution	Kyoto University
Principal Investigator	Mori Yasuo 京都大学, 工学研究科, 教授 (80212265)
Co-Investigator(Kenkyū-buntansha)	赤池孝章東北大学, 医学系研究科, 教授 (20231798) 浦野泰照東京大学, 大学院薬学系研究科(薬学部), 教授 (20292956) 飛田成史群馬大学, 大学院理工学府, 教授 (30164007) 山本雅之東北大学, 医学系研究科, 教授 (50166823) 中川秀彦名古屋市立大学, 大学院薬学研究科, 教授 (80281674) 三木裕明大阪大学, 微生物病研究所, 教授 (80302602) 南学正臣東京大学, 医学部附属病院, 教授 (90311620)
Research Collaborator	INOUE masahiro MIURA kyoko SUMIMOTO hideki ITOH ken UCHIDA kouji SUEMATSU makoto SOGA tomoyoshi TANIGUCHI naoyuki
Project Period (FY)	2014-07-10 – 2019-03-31
Keywords	酸素 / 活性酸素種 / 細胞シグナル / イメージング
Outline of Final Research Achievements	In order to demonstrate oxygen environment as molecular entities in living organisms, technical cores which give technique supports to area members were formed. In the area meetings, scientific achievements of area members were reported annually, and the direction of area managements, the strategy to foster young researchers, and the evaluation standard to call for area members were discussed. Many domestic and international symposia and workshops were organized along with annual meetings of different societies were held by our area. Aiming at enhancing networks among young scientists, meetings were arranged twice in collaboration with the innovative area "Dying Codes". Moreover, a special issue entitled "Oxygen Biology", to which area members contributed chapters, was arranged by our area and published in the Japanese scientific magazine "Cell".
Free Research Field	分子生理学
Academic Significance and Societal Importance of the Research Achievements	当該領域は大きく変化、拡大しており、有機的に組織化しなければ、研究者間の相互連携が取りにくい分散的状況にあった。しかし、本領域の活動により、この解決に向けた大きな一歩を踏み出すことができた。また、総括班を介した本領域での異分野の世界的な統合・再構築は、日本の学術レベルと世界におけるプレゼンスの向上・強化に貢献した。本領域は基礎生物学、医科学、薬学、農学を含めた幅広い分野に関係し、臨床医学、医工学、食品・発酵化、環境科学やケミカルバイオロジーといった学際・応用分野の発展にも結び付く。さらに、共通のプラットフォームである酸素生物学に多様な世代が本領域に集結することは、人材育成に結びついた。