2020 Fiscal Year Final Research Report
Understanding the map-based navigation system in the hippocampus of rats
| Project Area | Systems Science of Bio-navigation |
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| Project/Area Number |
16H06543
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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| Allocation Type | Single-year Grants |
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| Review Section |
Complex systems
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| Research Institution | Doshisha University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
苅部 冬紀 同志社大学, 研究開発推進機構, 准教授 (60312279)
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| Project Period (FY) |
2016-06-30 – 2021-03-31
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| Keywords | 場所細胞 |
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| Outline of Final Research Achievements |
In this study, we developed a maze in which the components of the maze including runways, sensors, movable walls, feeders, and treadmills, can be flexibly reconfigured. In addition, we constructed a logger system that can wirelessly record neuronal activities even outside the laboratory. Using these tools, we have advanced the understanding of spatial navigation in rodents and discovered grid cells in the medial pallium of Streaked shearwaters. Moreover, we discovered head direction cells in the telencephalon of salmonids (trout). We contributed to the development of DeepHL, an animal trajectory analysis method, and were able to discover those characteristic behaviors, which can identify movement disorders, appear in the maximum distance traveled at a certain time. These results have facilitated the understanding of navigation in the research field of Systems Science of Bionavigation.
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| Free Research Field |
認知神経科学
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| Academic Significance and Societal Importance of the Research Achievements |
本研究で開発した再構成可能な迷路や無線神経活動ロガーは、それぞれ独創性を備えた技術である。そのような認知神経科学、情報工学、実験心理学という異なる研究分野に加え、本領域内の共同研究により生態学、制御工学、データ科学分野を、ナビゲーション機能をシステム的に理解するという一つの具体的な目標の実現に向け融合させたという点で、本計画研究は世界的にも例のない極めて独創的な試みと言える。
本研究の成果は、移動障害を行動から検知する見守りシステムや、認知障害発症を予測する早期発見システムの開発に繋がる。更にはカーナビゲーション経路の最適化や、交通渋滞の緩和への応用も期待できる。
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