Study of Supra Functional Systems by Advanced Molecular Spectroscopy

2009 Fiscal Year Self-evaluation Report

• Project Area: Molecular Science for Supra Functional Systems ? Development of Advanced Methods for Exploring Elementary Process
• Project/Area Number: 19056009
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: The Institute of Physical and Chemical Research
• Principal Investigator: TAHARA Tahei The Institute of Physical and Chemical Research, 田原分子分光研究室, 主任研究員 (60217164)
• Project Period (FY): 2007 – 2011
• Keywords: 凝縮相 / ダイナミクス / 超高速分光 / 非線形分光 / 時空間分光計測 / 相関分光 / 分子複雑系 / 生体関連分子

Research Abstract

溶液をはじめとする凝縮相の分子科学研究においては、これまで単純分子系の研究によって蓄積した深い知識と高い技術を、いかに新しい問題の解明に向けるかが重要な課題である。そのターゲットの一つは、間違いなく生体系を頂点とする複雑系における分子の性質と機能の理解と制御である。本研究では、世界的にみてトップレベルにあるわれわれの分光計測技術を発展させ、さらに新しい極限的分光計測方法論の開発を行うとともに、高次構造を有する複雑分子系の研究を行う。具体的には以下の3つを骨子とする。
(1) 超高速分光を用いた生体分子系のダイナミクスの解明と機能発現機構の解明、
(2) 界面選択的な新規非線形分光の開発とそれを用いた生体モデル系界面の分光計測、
(3) 極限的時空間分光計測法の開発と細胞を含む複雑系における分子ダイナミクスの実測。

Research Products

• [Journal Article] Infrared-induced coherent vibration of a hydrogen-bonded system:Effects of mechanical and electrical anharmonic couplings (2009)
  • Author(s): K. Ishii, S. Takeuchi, T. Tahara
  • Journal Title: J. Chem. Phys. 131 Pages: 044512/1-044512/9
  • Peer Reviewed
• [Journal Article] Hidden electronic state of enhanced green fluorescent protein (2008)
  • Author(s): H. Hosoi, S. Yamaguchi, H. Mizuno, A. Miyawaki, T. Tahara
  • Journal Title: J. Phys. Chem. B 112 Pages: 2761-2763
  • Peer Reviewed
• [Journal Article] Heterodyne-detected electronic sum frequency generation: "Up" vs. "down" alignment of interfacial molecules (2008)
  • Author(s): S. Yamaguchi, T. Tahara
  • Journal Title: J. Chem. Phys. 129 Pages: 101102/1-101102/4
  • Peer Reviewed
• [Journal Article] Ultrafast pump-probe study of primary photoreaction dynamics in pharaonis halorhodopsin: Halide-ion dependence and isomerization dynamics (2008)
  • Author(s): T. Nakamura, S. Takeuchi, M. Shibata, M. Demra, H. Kandori, T. Tahara
  • Journal Title: J. Phys. Chem. B 112 Pages: 12795-12800
  • Peer Reviewed
• [Journal Article] Spectroscopic tracking of structural evolution in ultrafast stilbene photoisomerization (2008)
  • Author(s): S. Takeuchi, S. Ruhman, T. Tsuneda, M. Chiba, T. Taketsugu, T. Tahara
  • Journal Title: Science 322 Pages: 1073-1077
  • Peer Reviewed
• [Presentation] Development of New Interface-Selective Nonlinear Spectroscopy and Its Application (2009)
  • Author(s): T. Tahara
  • Organizer: Second Asian Spectroscopy Conference
  • Place of Presentation: Seoul, Korea
  • Year and Date: 20091131-20091202
• [Presentation] Observing structural evolution of reacting molecules: ultrafast photoisomerization of cis-stilbene (2009)
  • Author(s): T. Tahara
  • Organizer: Femtochemitry IX
  • Place of Presentation: Beijing, China
  • Year and Date: 20090808-20090813
• [Presentation] Ultrafast Photochemical Dynamics Studied by Femtosecond Time-Resolved Fluorescence Spectroscopy (2009)
  • Author(s): T. Tahara
  • Organizer: Fluorescence 2009
  • Place of Presentation: Mumbai, India
  • Year and Date: 20090316-20090319
• [Presentation] Looking for the reaction coordinate of photoisomerization of cis-stilbene (2008)
  • Author(s): T. Tahara
  • Organizer: Gordon Conference on Vibrational Spectroscopy
  • Place of Presentation: South Hadley, MA, USA.
  • Year and Date: 20080803-20080808
• [Presentation] New interface-selective electronic nonlinear spectroscopy and its relevance to two-dimensional spectroscopy (2008)
  • Author(s): T. Tahara
  • Organizer: 4th International Conference on Coherent Multidimensional Spectroscopy
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 20080803-20080808
• [Book] Biochemical Application of Nonlinear Optical Spectroscopy(Ultrafast Fluorescence Microscope) (2009)
  • Author(s): T. Fujino, T. Tahara
  • Total Pages: 53-72
  • Publisher: CRC Press
• [Remarks]
  • URL: http://www.riken.go.jp/lab-www/spectroscopy