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2009 Fiscal Year Self-evaluation Report

Cell cycle regulation of cell morphology and cell size

Planned Research

  • PDF
Project AreaCell Proliferation Control
Project/Area Number 19057002
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe University of Tokyo

Principal Investigator

OHYA Yoshikazu  The University of Tokyo, 大学院・新領域創成科学研究科, 教授 (20183767)

Project Period (FY) 2007 – 2012
Keywords出芽酵母 / 細胞壁 / 細胞周期 / 細胞形態 / 画像解析
Research Abstract

従来、細胞周期の研究では、DNA複製、染色体凝集、染色体分配、細胞質分裂などの事象を対象にした研究が広く行われてきたが、最近になって、細胞増殖サイクルを可能にする空間(場)の提供という観点から、細胞周期に依存した細胞のサイズや形態形成の研究が脚光を浴びてきている。研究代表者は、今まで単細胞生物である出芽酵母と分裂酵母の特徴を生かして、細胞周期と細胞空間形成の連携に関する研究を行った。

  • Research Products

    (12 results)

All 2010 2009 2008 2007 2006 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (5 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Multiple Functional Domains of the Yeast 1, 3-β-Glucan Synthase Subunit Fks1p Revealed by Quantitative Phenotypic Analysis of Temperature-Sensitive Mutants Genetics Epub2010

    • Author(s)
      Okada H, Abe M, Asakawa-Minemura M, Hirata A, Qadota H, Morishita K, Ohnuki S, Nogami S, Ohya Y
    • Journal Title

      (in press)

    • Peer Reviewed
  • [Journal Article] Comprehensive and quantitative analysis of yeast deletion mutants defective in apical and isotropic bud growth Current Genetics2009

    • Author(s)
      Watanabe M, Watanabe D, Nogami S, Morishita S, Ohya Y
    • Journal Title

      Epub 55(4)

      Pages: 365-80

    • Peer Reviewed
  • [Journal Article] G1/S Cyclin-Dependent Kinase Regulates Small GTPase Rho1p through Phosphorylation of RhoGEF Tus1p in Saccharomyces cerevisiae.2008

    • Author(s)
      Kono K, Nogami S, Abe M, Nishizawa M, Morishita S, Pellman D, Ohya Y.
    • Journal Title

      Mol Biol Cell 19(4)

      Pages: 1763-71

    • Peer Reviewed
  • [Journal Article] Genetic complexity and QTL mapping of yeast morphological traits.2007

    • Author(s)
      Nogami S, Ohya Y, Yvert G.
    • Journal Title

      PLOS Genet. 3

      Pages: e31

    • Peer Reviewed
  • [Journal Article] Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast.2006

    • Author(s)
      Parsons, A.B., Lopez, A., Givoni, I.E., Williams, D.E., Gray, C.A., Porter, J., Chua, G., Sopko, R., Brost, R.L., Ho, C.-H., Wang, J., Ketela, T., Brenner, C., Brill, J.A., Fernandez, G.E., Lorenz, T.C., Payne, G.S., Ishihara, S., Ohya Y.,rews, B., Hughes, T.R., Frey, B.J., Graham, T.R.,ersen, R.J., Boone, C.
    • Journal Title

      Cell 126

      Pages: 611-25

    • Peer Reviewed
  • [Presentation] 出芽酵母の細胞壁チェックポイントシグナル伝達機構の解明2009

    • Author(s)
      菊地陽
    • Organizer
      第32回日本分子生物学会年会パシフィコ
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
  • [Presentation] Cell wall integrity checkpoint2009

    • Author(s)
      大矢禎一
    • Organizer
      Molecular Mechanisms of Fungal Cell Wall Biogenesis Staszic Palace
    • Place of Presentation
      Historical District of Warsaw
    • Year and Date
      2009-09-02
  • [Presentation] Chemical genomics to understand cell morphology of Saccharomyces cerevisia2007

    • Author(s)
      Ohya Y
    • Organizer
      Symposium on Systems Biology Initiative
    • Year and Date
      2007-11-18
  • [Presentation] Dynactin and its interacting molecules are involved in cell wall integrity checkpoint of Saccharomyces cerevisiae2007

    • Author(s)
      Ohya Y
    • Organizer
      Intern at ioal Work shop on Cell Regul at ions in Div is ionand Arrest OIS T Seai d e H o u s e
    • Place of Presentation
      Okinawa
    • Year and Date
      2007-03-23
  • [Presentation] Cell wall integrity checkpoint that monitors cell wall remodeling in Saccharomyces cerevisiae2007

    • Author(s)
      Ohya Y
    • Organizer
      The first International Fungal / Plant Cell Wall Meeting Village de Vancances Familiales de Anglet
    • Place of Presentation
      Biarritz, France
    • Year and Date
      2007-03-12
  • [Remarks]

    • URL

      http://ps.k.u-tokyo.ac.jp/

  • [Patent(Industrial Property Rights)] 細胞形態定量値を用いる酵母の生理状態の評価方法2009

    • Inventor(s)
      大矢禎一、野上識、大貫慎輔(東京大学)、善本裕之、榎本賢一、堀越杏子(キリンビール醸造研究所)
    • Industrial Property Rights Holder
      キリンビール
    • Industrial Property Number
      2009-0088
    • Filing Date
      2009-07-27

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

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