Chemistry and biology of π-rich molecules

2010 Fiscal Year Self-evaluation Report

• Project Area: Emergence of highly elaborated pai-space and its function
• Project/Area Number: 20108015
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Tohoku University
• Principal Investigator: ISOBE Hiroyuki Tohoku University, 大学院・理学研究科, 教授 (30302805)
• Project Period (FY): 2008 – 2012
• Keywords: π豊富分子 / フラーレン / 生物有機化学 / 有機エレクトロニクス

Research Abstract

本研究はπ電子豊富分子の特異な構造・物性に着目し,それを活用した生体内機能性分子および生体模倣分子の設計合成を行う.

Research Products

• [Journal Article] Electron mobility in a mercury-mediated duplex of triazole-linked DNA (TLDNA) (2011)
  • Author(s): Isobe, H... ; Yamazaki, N. ; Asano, A. ; Fujino, T. ; Nakanishi, W. ; Seki, S.
  • Journal Title: Chem.Lett. 40(3) Pages: 318-319
  • URL: http://dx.doi.org/10.1246/cl.2011.318
• [Journal Article] In vivo gene delivery by cationic tetraamino fullerene (2010)
  • Author(s): Maeda-Mamiya, R.; Noiri, E.; .Isobe, H.; Nakanishi, W.; Okamoto, K.; Doi, K.; Sugaya, T.; Izumi, T.; Homma, T.; Nakamura, E
  • Journal Title: Proc. Natl. Acad. Sci., U.S.A. Volume: 107 (12) Pages: 5339-5344
  • URL: http://dx.doi.org/10.1073/pnas.0909223107
  • Peer Reviewed
• [Journal Article] Disilanyl double-pillaredbisanthracene : A bipolar carrier transport material for organic light emitting diode devices (2010)
  • Author(s): Nakanishi, W. ; Hitosugi, S. ; Piskareva, A. ; Shimada, Y. ; Taka, H. ; Kita, H. ; Isobe, H.
  • Journal Title: Angew.Chem.Int.Ed. 49(40) Pages: 7239-7242
  • URL: http://dx.doi.org/10.1002/anie.201002432
• [Journal Article] Synthesis and structures of deoxyribonucleoside analogues for triazole-linked DNA (TLDNA) (2010)
  • Author(s): Fujino, T. ; Tsunaka, N. ; Guillot-Nieckowski, M. ; Nakanishi, W. ; Iwamoto, T. ; Nakamura, E. ; Isobe, H.
  • Journal Title: Tetrahedron Lett. 51(15) Pages: 2036-2038
  • URL: http://dx.doi.org/10.1016/j.tetlet.2010.02.046
• [Journal Article] Concise synthesis of halogenated chrysenes ([4]phenacenes) that favor π-stack packing in single crystals (2009)
  • Author(s): Isobe, H.. ; Hitosugi, S. ; Matsuno, T. ; Iwamoto, T. ; Ichikawa, J.
  • Journal Title: Org.Lett. 11(17) Pages: 4026-4028
  • URL: http://dx.doi.org/10.1021/ol901693y
• [Presentation] Functional Assembly of Amphiphilic Carbon Clusters (2010)
  • Organizer: 9th International Symposium on Functional π-Electron Systems
  • Place of Presentation: Georgia, U.S.A.(Plenary Lecture)
  • Year and Date: 2010-05-28
• [Remarks]
  • URL: http://www.orgchem2.chem.tohoku.ac.jp
• [Patent(Industrial Property Rights)] 縮退系大環状化合物、並びに、その結晶及び製造方法 (2010)
  • Inventor(s): 磯部寛之、中西和嘉、吉岡知昭
  • Industrial Property Rights Holder: 東北大学
  • Industrial Property Number: 特許,2010-275387
  • Filing Date: 2010-12-10