Neural Network on Choice of Behavior to Multiple Sensory Inputs

2012 Fiscal Year Final Research Report

• Project Area: Systems molecular ethology to understand the operating principle of the nervous system
• Project/Area Number: 20115004
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Iwate University
• Principal Investigator: SHINGAI Ryuzo 岩手大学, 工学部, 名誉教授 (00089088)
• Co-Investigator(Kenkyū-buntansha): IWASAKI Yuishi 茨城大学, 工学部, 助教 (50282281) ; WAKABAYASHI Tokumitsu 岩手大学, 工学部, 助教 (30332498)
• Co-Investigator(Renkei-kenkyūsha): GOMI Sohei 岩手大学, 人文社会科学部, 准教授 (30271836) ; SAKATA Kazumi 岩手大学, 工学部, 助教 (80261163)
• Project Period (FY): 2008 – 2012
• Keywords: 行動解析 / カルシウムイメージング / 数理モデル / 神経モデル

Research Abstract

In order to understand the relationship between the nervous system and behavior of C.θ1θgans, we developed software to analyze the behavior. The method to identify automatically the behavioral states (forward movement, turn etc.) was refined, and a novel method to evaluate periodicity and irregularity of the head movement was proposed. By using these methods, we found the difference of head movements among the wild type and several mutant strains, and the head movement age-dependency. The quantitative behavioral analysis, behavioral model, and neural model were utilized to understand the behavioral choice when two sensory inputs were applied simultaneously, and that in the acid avoidance behavior.

Research Products

• [Journal Article] Evaluation of head movement periodicity and irregularity during locomotion of Caenorhabditis elegans (2013)
  • Author(s): Shingai R., Furudate M., Hoshi K., Iwasaki Y
  • Journal Title: Front. Behav. Neurosci Volume: 7 Pages: 20
  • DOI: doi:10.3389/fnbeh.2013.00020
  • Peer Reviewed
• [Journal Article] A model of the intracellular response of an olfactory neuron in Caenorhabditis elegans to odorstimulation (2012)
  • Author(s): Usuyama, M., Ushida, C., Shingai, R
  • Journal Title: PLoS ONE Volume: 7(8) Pages: e42907
  • DOI: doi:10.1371/journal.pone.0042907
  • Peer Reviewed
• [Journal Article] Odour concentration-dependent olfactory preference change in C. elegans (2012)
  • Author(s): Yoshida, K., Hirotsu, T., Tagawa, T., Oda, S., Wakabayashi, T., Iino, Y., Ishihara, T
  • Journal Title: Nature Comms Volume: 3 Pages: 739
  • DOI: doi:10.1038/ncomms1750
  • Peer Reviewed
• [Journal Article] Quantitative modeling of neuronal dynamics in C. elegans (2010)
  • Author(s): Kuramochi, M., lwasaki, Y
  • Journal Title: Lecture Notes in Computer Science (Springer-Verlag) Volume: 6443 Pages: 17-24
  • Peer Reviewed
• [Journal Article] In vivo calcium imaging of OFF-responding ASK neurons in C. elegans (2009)
  • Author(s): WakabaVashi L Kimura, Y, Ohba, Y., Adachi, R., Satoh, Y.,and Shinqai, R
  • Journal Title: BBA Gen. Subj Volume: 1790 Pages: 765-769
  • DOI: doi:10.1016/j.bbagen.2009.03.032
  • Peer Reviewed
• [Presentation] 冨田浩史 「線虫は、幼生の生育や成虫の運動に対して毒性を持つレア・アース元素を化学感覚器で検出し、忌避行動を示す (2012)
  • Author(s): 若林篤光、(他2名)
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡国際会議場(福岡県)
  • Year and Date: 20121211-14
• [Presentation] Computational evaluation of odor gradient in chemotaxis assay (2012)
  • Author(s): Iwasaki,Y., Ichijo, H., Shingai, R., Yamazoe, A., Kimura, K
  • Organizer: 5th East Asia C. elegans Meeting
  • Place of Presentation: Taipei (Taiwan)
  • Year and Date: 20120627-30
• [Presentation] Navigational decision-making during acidc pH avoidance in C. elegans (2012)
  • Author(s): Wakabayashi, T., Sakata, K., Shingai, R
  • Organizer: EMBO Conference Series: C. elegans Neurobiology
  • Place of Presentation: Heidelberg (Germany)
  • Year and Date: 20120614-17
• [Presentation] 線虫のニューロンと蛍光Ca2+インジケータに関する動的モデル (2012)
  • Author(s): 岩崎唯史
  • Organizer: 新学術領域「システム分子行動学」数理シンポジウム
  • Place of Presentation: 東京大学(東京都)
  • Year and Date: 20120511-12
• [Presentation] Intracellular response model of an olfactory neuron in C.elegans (2011)
  • Author(s): Usuyama, M., Shingai, R., Ichinose, M
  • Organizer: Neuroscience 2011
  • Place of Presentation: Washington DC (USA)
  • Year and Date: 20111112-16
• [Presentation] Neural circuit model for head swing and forward/backward movement of C. elegans (2011)
  • Author(s): Shingai, R., Takahashi, H., Iwasaki, Y
  • Organizer: Neuroscience 2011
  • Place of Presentation: Washington DC (USA)
  • Year and Date: 20111112-16
• [Presentation] 線虫C.elegans 嗅覚受容ニューロンは味覚刺激により活性化する (2011)
  • Author(s): 一條宏, 若林篤光,(他3名), 新貝鉚蔵
  • Organizer: 第34回日本神経科学大会P4-K17
  • Place of Presentation: パシフィコ横浜(神奈川県)
  • Year and Date: 20110914-17
• [Presentation] 非対称性を取り入れた線虫感覚神経系のコンピュータシミュレーション (2011)
  • Author(s): 坂田和実,山田雅史,岩崎唯史,秋田宙樹,若林篤光,新貝釦蔵,小栗栖太郎
  • Organizer: 第34回日本神経科学大会P4-uO6
  • Place of Presentation: パシフィコ横浜(神奈川県)
  • Year and Date: 20110914-17
• [Presentation] C.エレガンスのモデル神経回路における周期的興奮(Periodic excitation in amodel neural network of C. elegans) (2011)
  • Author(s): Shingai, R., Takahashi, H Iwasaki, Y., Ogurusu, T
  • Organizer: 第34回日本神経科学大会 Oral Session
  • Place of Presentation: パシフィコ横浜(神奈川県)
  • Year and Date: 20110914-17
• [Presentation] Neuronal modeling toward quantitative understanding of nervous system of C. elegans (2011)
  • Author(s): Iwasaki, Y., Kuramochi, M., Sakata, K., Oda, S.,lino, Y., and Shingai, R
  • Organizer: 18th International C. elegans Meeitng 545C
  • Place of Presentation: UCLA, CA(USA)
  • Year and Date: 20110622-26
• [Presentation] Dynamical model variables, calcium imaging and design of C. elegans neuron (2011)
  • Author(s): Kuramochi, M., Sakata, K., Sakata, K., Shingai R., Iwasaki Y
  • Organizer: The 7th Asian Biophysical Association Symposium
  • Place of Presentation: New Delhi(India)
  • Year and Date: 2011-01-30
• [Presentation] Computersimulation for neural network of C. elegans (2010)
  • Author(s): Shingai, R., Takahashi, H., Iwasaki, Y., Sakata, K., Wakabavashi, T., Ogurusu, T
  • Organizer: 4^<th> East Asia C. elegans Meeting
  • Place of Presentation: 国立オリンピック記念青少年記念センター(東京都)
  • Year and Date: 20100711-14
• [Presentation] Simultaneous presentation of two attractants modifies taxis behavior in C. elegans (2010)
  • Author(s): Shingai, R
  • Organizer: 第87回日本生理学会大会
  • Place of Presentation: マリオス、盛岡(岩手県)
  • Year and Date: 20100519-21
• [Presentation] Quantitative modeling of neuronal dynamics in C. elegans (2010)
  • Author(s): Kuramochi, M., lwasaki, Y
  • Organizer: 17th International Conference on Neural Information Processing (ICONIP2010)
  • Place of Presentation: Sydney(Australia)
  • Year and Date: 2010-11-22
• [Presentation] C.エレガンスの部分神経回路のシミュレーション (2009)
  • Author(s): 祝田尚之、岩崎唯史、若林篤光、新貝釧蔵
  • Organizer: BPES 2009 第24回生体・生理工学シンポジウム(依頼講演)
  • Place of Presentation: 東北大学(宮城県)
  • Year and Date: 20090924-26
• [Presentation] C.エレガンス嗅覚受容ニューロンの細胞内Ca^<2+>応答モデル (2009)
  • Author(s): 宇壽山 衛、(他2名)、新貝釧蔵
  • Organizer: 第19回日本数理生物学会年会
  • Place of Presentation: 東京大学(東京都)
  • Year and Date: 20090909-11
• [Presentation] Behavioral decision-making during acidic pH avoidance in C. elegans (2009)
  • Author(s): Wakabavashi, T., Togashi, T., Shingai, R
  • Organizer: 17th International C. elegans Meeting, 536B
  • Place of Presentation: UCLA, CA(USA)
  • Year and Date: 20090624-28
• [Presentation] 複数入力に対する行動選択 (2009)
  • Author(s): 新貝釧蔵
  • Organizer: 日本生物物理学会東北支部会シンポジウム(招待講演)
  • Place of Presentation: 東北大学(宮城県)
  • Year and Date: 2009-09-11
• [Presentation] 線虫CelegansのASK感覚神経細胞のカルシウムイメージング (2008)
  • Author(s): 若林篤光、(他3名)、新貝釧蔵
  • Organizer: 第31回日本分子生物学会年会
  • Place of Presentation: 神戸ポートアイランド(兵庫県)
  • Year and Date: 2008-12-11
• [Remarks]
  • URL: http://ims.dse.ibaraki.ac.jp/research/C_elegans.html