Model Construction of Computational Anatomy

2013 Fiscal Year Final Research Report

• Project Area: Computational anatomy for computer-aided diagnosis and therapy :Frontiers of medical image sciences
• Project/Area Number: 21103004
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Gifu University
• Principal Investigator: FUJITA Hiroshi 岐阜大学, 医学(系)研究科(研究院), 教授 (10124033)
• Co-Investigator(Kenkyū-buntansha): HARA Takeshi 岐阜大学, 大学院医学系研究科, 准教授 (10283285) ; ZHOU Xiangrong 岐阜大学, 大学院医学系研究科, 助教 (00359738)
• Co-Investigator(Renkei-kenkyūsha): HOSHI Hiroaki 岐阜大学, 大学院医学系研究科, 教授 (60128395) ; CHEN Huayue 岐阜大学, 大学院医学系研究科, 講師 (20273146)
• Research Collaborator: 兼松 雅之 岐阜大学 ; 福岡 大輔 岐阜大学 ; 村松 千左子 岐阜大学 ; 横山 龍二郎 岐阜大学 ; 林 達郎 岐阜大学 ; 神谷 直希 豊田工業高等専門学校 ; 寺本 篤司 藤田保健衛生大学 ; 松原 友子 名古屋文理大学 ; 畑中 裕司 滋賀県立大学 ; 内山 良一 熊本大学 ; 張 学軍 中国・広西大学 ; 姜 慧研 中国・東北大学 ; SONG Wang 米国 South Carolina 大学
• Project Period (FY): 2009-07-23 – 2014-03-31
• Keywords: 解剖学 / 臓器モデル / 画像認識 / 医用画像 / 診断・治療支援

Research Abstract

The purpose of this research is to construct "computational anatomical models" and develop model-based computer-aided diagnosis (CAD) systems for several kinds of medical images from different modalities. A large database of medical images was constructed and the models on positions, ranges, variety of surface shapes, and density distributions of the image voxels for major organs and tissues were built. Then, we confirmed that the constructed statistic models were useful for automatic recognitions of 18 kinds of organs and tissues from torso X-ray CT images. In addition, these models were applied to the developments of the CAD systems designed for PET, MR, fundus photograph, dental panoramic radiograph, etc., and found to be effective.

Research Products

• [Journal Article] Hybrid method for the detection of pulmonary nodules using positron emission tomography/computed tomography: A preliminary study (2014)
  • Author(s): A.Teramoto, H.Fujita, K.Takahashi, O.Yamamuro, T.Tamaki, M.Nishio, and T.Kobayashi
  • Journal Title: International Journal of Computer Assisted Radiology and Surgery Volume: Vol.9 Pages: 59-69
  • DOI: 10.1007/s11548-013-0910-y
  • Peer Reviewed
• [Journal Article] Automated segmentation of psoas major muscle in X-ray CT images by use of a shape model: Preliminary study (2014)
  • Author(s): N.Kamiya, X.Zhou, H.Chen, C.Muramatsu, T.Hara, R.Yokoyama, M.Kanematsu, H.Hoshi, and H.Fujita
  • Journal Title: Radiological Physics and Technology Volume: Vol.5, No.1 Pages: 5-14
  • Peer Reviewed
• [Journal Article] Model constructions for computational anatomy: Fundamentals and applications (2013)
  • Author(s): H.Fujita, T.Hara, X.Zhou, C.Muramatsu, and N.Kamiya
  • Journal Title: Medical Imaging Technology Volume: Vol.31, No.5 Pages: 278-286
  • URL: http://jamit.co.jp/mit/index.html
• [Journal Article] Model-based approach to recognize the rectus abdominis muscle in CT images (2013)
  • Author(s): N.Kamiya, X.Zhou, H.Chen, C.Muramatsu, T.Hara, and H.Fujita
  • Journal Title: IEICE Transactions on Information and Systems Volume: Vol.E-96-D, No.4 Pages: 869-871
  • DOI: 10.1587/transinf.E96.D.869
  • Peer Reviewed
• [Journal Article] Liver segmentation based on snakes model and improved GrowCut algorithm in abdominal CT image (2013)
  • Author(s): H.Jiang, B.He, Z.Ma, M.Zong, X.Zhou, and H.Fujita
  • Journal Title: Computational and Mathematical Methods in Medicine Volume: Vol. 2013, Article ID: 958398 Pages: 12
  • URL: http://www.hindawi.com/journals/cmmm/2013/958398/
  • Peer Reviewed
• [Journal Article] Automated measurement of mandibular cortical width on dental panoramic radiographs (2013)
  • Author(s): C.Muramatsu, T.Matsumoto, T.Hayashi, T.Hara, A.Katsumata, X.Zhou, Y.Iida, M.Matsuoka, T.Wakisaka, and H.Fujita
  • Journal Title: International Journal of Computer Assisted Radiology and Surgery Volume: Vol.8, No.6 Pages: 877-885
  • DOI: 10.1007/s11548-012-0800-8
  • Peer Reviewed
• [Journal Article] Particle system based adaptive sampling on spherical parameter space to improve the MDL method for construction of statistical shape models (2013)
  • Author(s): R.Xu, X.Zhou, Y.Hirano, R.Tachibana, T.Hara, S.Kido, and H.Fujita
  • Journal Title: Computational and Mathematical Methods in Medicine Volume: Vol.2013, Article ID 196259 Pages: 9
  • URL: http://www.hindawi.com/journals/cmmm/2013/196259/
  • Peer Reviewed
• [Journal Article] Automatic organ localizations on 3D CT images by using majority-voting of multiple 2D detections based on local binary patterns and Haar-like features (2013)
  • Author(s): X.Zhou, A.Yamaguti, X.Zhou, T.Hara, R.Yokoyama, M.Kanematsu, and H.Fujita
  • Journal Title: Proc. of SPIE Medical Imaging 2013: Computer-Aided Diagnosis Volume: Vol.8670 Pages: 86703A-1 - 86703A-7
  • DOI: 10.1117/12.2007466
  • Peer Reviewed
• [Journal Article] Temporal subtraction system on torso FDG-PET scans based on statistical image analysis (2013)
  • Author(s): Y.Shimizu, T.Hara, D.Fukuoka, X.Zhou, C.Muramatsu, S.Ito, K.Hakozaki, S.Kumita, K.Ishihara, T.Katafuchi, and H.Fujita
  • Journal Title: Proc. of SPIE Medical Imaging 2013: Computer-Aided Diagnosis Volume: Vol.8670 Pages: 86703F-1 - 86703F-6
  • DOI: 10.1117/12.2007886
  • Peer Reviewed
• [Journal Article] MR elastography of the liver at 3 T with cine-tagging and bending energy analysis: Preliminary results (2010)
  • Author(s): H.Watanabe, M.Kanematsu, T.Kitagawa, Y.Suzuki, H.Kondo, S.Goshima, K.Kajita, K.T. Bae, Y.Hirose, S.Miotani, X.Zhou, and H.Fujita
  • Journal Title: European Radiology Volume: Vol.20 Pages: 2381-2389
  • DOI: 10.1007/s00330-010-1800-0
  • Peer Reviewed
• [Presentation] A01-3 Model construction for computational anatomy: Progress overview FY2009-FY2013 (2014)
  • Author(s): H.Fujita, T.Hara, X.Zhou, C.Muramatsu, N.Kamiya, M.Zhang, D.Fukuoka, Y.Hatanaka, T.Matsubara, A.Teramoto, Y.Uchiyama, H.Chen, and H.Hoshi
  • Organizer: The Fifth International Symposium on the Project "Computational Anatomy,"
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 20140308-09
• [Presentation] Preliminary study on differentiation between glaucomatous and non-glaucomatous eyes on stereo fundus images using cup gradient models (2014)
  • Author(s): C.Muramatsu, Y.Hatanaka, K.Ishida, A.Sawada, T.Yamamoto, and H.Fujita
  • Organizer: SPIE medical imaging 2014
  • Place of Presentation: San Diego, USA
  • Year and Date: 20140216-20
• [Presentation] 臓器位置検出とGrabCut による3 次元CT 画像からの複数臓器領域の自動検出 (2014)
  • Author(s): 伊藤隆晃,周 向栄,原 武史,姜 慧研,横山龍二郎,陳 華岳,兼松雅之,星 博昭,藤田広志
  • Organizer: メディカルイメージング連合フォーラム
  • Place of Presentation: 沖縄
  • Year and Date: 20140126-27
• [Presentation] 体幹部FDG-PET 画像における除脂肪体重を用いた正常モデルの構築と解析 (2014)
  • Author(s): 清水勇介,原 武史,福岡大輔,周 向栄,村松千左子,伊藤 哲,箱崎謙太,汲田伸一郎,石原圭一,片渕哲朗,藤田広志
  • Organizer: メディカルイメージング連合フォーラム
  • Place of Presentation: 沖縄
  • Year and Date: 20140126-27
• [Presentation] State-of-the-art of Computer-Aided Detection/Diagnosis (CAD) for Medical Images (2013)
  • Author(s): H.Fujita
  • Organizer: First Aizu Conference on Biomedical Informatics and Technology (ACBIT'2013)
  • Place of Presentation: Aizuwakamatsu, Japan
  • Year and Date: 20130916-17
• [Presentation] CAD applications in diverging diagnostic imaging field (2013)
  • Author(s): H.Fujita
  • Organizer: CARS 2013
  • Place of Presentation: Heidelberg, Germany
  • Year and Date: 20130626-29
  • Invited
• [Presentation] 「計算解剖学」研究とそのパノラマ画像解析への応用 (2013)
  • Author(s): 藤田広志
  • Organizer: 日本歯科放射線学会 第33回関西・九州合同地方会
  • Place of Presentation: じゅうろくプラザ,岐阜
  • Year and Date: 2013-12-14
• [Presentation] State-of-the-art of computer-aided diagnosis (CAD) in medical images (2013)
  • Author(s): H.Fujita
  • Organizer: The International Symposium on Electrical-Electronics Engineering (ISEE2013)
  • Place of Presentation: Ho Chi Minh City, Vietnam
  • Year and Date: 2013-11-01
• [Presentation] Fast organ localization and FDG-PET modeling, Workshop: Whole-Body Computational Anatomy and its Application to Computer Aided Diagnosis and Therapy (2013)
  • Author(s): H.Fujita, T.Hara, and X.Zhou
  • Organizer: 35th Annual International Conference of IEEE Engineering in Medicine and Biology Society (IEEE EMBC 2013)
  • Place of Presentation: Osaka
  • Year and Date: 2013-07-03
• [Presentation] Automated segmentation of recuts abdominis muscle using shape model in X-ray CT images (2011)
  • Author(s): N.Kamiya, X.Zhou, H.Chen, C.Muramatsu, T.Hara, R.Yokoyama, M.Kanematsu, H.Hoshi, and H.Fujita
  • Organizer: 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC 2011)
  • Place of Presentation: Boston, USA
  • Year and Date: 20110830-0904
• [Book] Computer-aided image analysis for vertebral anatomy on X-ray CT images (Chapter 7), ed. by K.Suzuki, in Computational Intelligence in Biomedical Imaging (2014)
  • Author(s): T.Hayashi, H.Chen, K.Miyamoto, X.Zhou, T.Hara, and H.Fujita
  • Total Pages: 406
  • Publisher: Springer, New York
• [Book] 実践 医用画像解析ハンドブック (2012)
  • Author(s): 藤田広志,石田隆行,桂川茂彦(監修); 藤田広志,石田隆行,桂川茂彦,原 武史,目加田慶人,加野亜紀子,羽石秀昭(共編); 藤田広志,原 武史,周 向栄,村松千左子,他(分担執筆)
  • Total Pages: 835
  • Publisher: オーム社,東京
• [Book] Automatic organ localization on X-ray CT images by using ensemble-learning techniques, in Machine Learning in Computer-Aided Diagnosis: Medical Imaging Intelligence and Analysis, ed. by K.Suzuki (2012)
  • Author(s): X.Zhou and H.Fujita
  • Total Pages: 500
  • Publisher: IGI Global, USA
• [Book] 医用画像ハンドブック (2010)
  • Author(s): 石田隆行,桂川茂彦,藤田広志 監修
  • Total Pages: 1571
  • Publisher: オーム社
• [Remarks]
  • URL: http://www.fjt.info.gifu-u.ac.jp