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2014 Fiscal Year Final Research Report

Metabolomics-assisted genome mining for biosynthesis of plant metabolites

Planned Research

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Project AreaBiosynthetic machinery: Deciphering and regulating the system for bioactive metabolite diversification
Project/Area Number 22108008
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionChiba University

Principal Investigator

SAITO Kazuki  千葉大学, 薬学研究科(研究院), 教授 (00146705)

Co-Investigator(Kenkyū-buntansha) YAMAZAKI Mami  千葉大学, 大学院薬学研究院, 准教授 (70222370)
Co-Investigator(Renkei-kenkyūsha) YOSHIMOTO Naoko  千葉大学, 大学院薬学研究院, 助教 (10415333)
SAKAKIBARA Keiko  独立行政法人理化学研究所, 環境資源科学研究センター, 上級研究員 (20360555)
FUKUSHIMA Atsushi  独立行政法人理化学研究所, 環境資源科学研究センター, 研究員 (80415281)
NAKABAYASHI Ryo  独立行政法人理化学研究所, 環境資源科学研究センター, 特別研究員 (30586160)
KUSANO Miyako  独立行政法人理化学研究所, 植物科学研究センター, 上級研究員 (60415148)
Project Period (FY) 2010-04-01 – 2015-03-31
Keywords生合成 / 植物二次代謝 / メタボロミクス / 統合オミクス
Outline of Final Research Achievements

Plant metabolites are useful for our daily life as food, medicines and raw materials for industry. In this study, we have investigated the mechanism and regulation for the biosynthesis of plant metabolites by means of functional genomics, molecular biology and biochemistry. We have identified some genes involved in the biosynthesis of anti-cancer camptothecin, quinolizidine alkaloids and sulfur-containing metabolites from plants.

Free Research Field

天然資源系薬学、植物ゲノム機能科学、植物バイオテクノロジー

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Published: 2016-06-03  

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