2014 Fiscal Year Final Research Report
Metabolomics-assisted genome mining for biosynthesis of plant metabolites
Project Area | Biosynthetic machinery: Deciphering and regulating the system for bioactive metabolite diversification |
Project/Area Number |
22108008
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Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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Allocation Type | Single-year Grants |
Review Section |
Science and Engineering
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Research Institution | Chiba University |
Principal Investigator |
SAITO Kazuki 千葉大学, 薬学研究科(研究院), 教授 (00146705)
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Co-Investigator(Kenkyū-buntansha) |
YAMAZAKI Mami 千葉大学, 大学院薬学研究院, 准教授 (70222370)
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Co-Investigator(Renkei-kenkyūsha) |
YOSHIMOTO Naoko 千葉大学, 大学院薬学研究院, 助教 (10415333)
SAKAKIBARA Keiko 独立行政法人理化学研究所, 環境資源科学研究センター, 上級研究員 (20360555)
FUKUSHIMA Atsushi 独立行政法人理化学研究所, 環境資源科学研究センター, 研究員 (80415281)
NAKABAYASHI Ryo 独立行政法人理化学研究所, 環境資源科学研究センター, 特別研究員 (30586160)
KUSANO Miyako 独立行政法人理化学研究所, 植物科学研究センター, 上級研究員 (60415148)
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Project Period (FY) |
2010-04-01 – 2015-03-31
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Keywords | 生合成 / 植物二次代謝 / メタボロミクス / 統合オミクス |
Outline of Final Research Achievements |
Plant metabolites are useful for our daily life as food, medicines and raw materials for industry. In this study, we have investigated the mechanism and regulation for the biosynthesis of plant metabolites by means of functional genomics, molecular biology and biochemistry. We have identified some genes involved in the biosynthesis of anti-cancer camptothecin, quinolizidine alkaloids and sulfur-containing metabolites from plants.
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Free Research Field |
天然資源系薬学、植物ゲノム機能科学、植物バイオテクノロジー
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