Planned Research
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Blood vessel networks running throughout the body carry blood to supply oxygen and nutrients to all the cells in the body. In this study, we have investigated the molecular mechanism of vascular network formation by performing multidimensional fluorescence live-imaging analyses using zebrafish as a model animal. Here, we have clarified 1) the signaling pathways underlying endothelial cell morphology and motility during angiogenesis, 2) the role of transcriptional regulator -catenin in vascular development and 3) the regulatory mechanism of endothelial cell proliferation during vascular development.
血管生物学
