Development of bioinformatics platform for analyzing chromosome dynamics and comparative genomics.

2014 Fiscal Year Final Research Report

• Project Area: Systematic study of chromosome adaptation
• Project/Area Number: 22125008
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: ITOH TAKEHIKO 東京工業大学, 生命理工学研究科, 教授 (90501106)
• Co-Investigator(Kenkyū-buntansha): SHIRAHIGE Katsuhiko 東京大学, 分子細胞学研究所, 教授 (90273854)
• Project Period (FY): 2010-04-01 – 2015-03-31
• Keywords: 染色体動態 / バイオインフォマティクス

Outline of Final Research Achievements

We developed novel ChIP-seq analysis, genome assembling and detecting point or structural variation algorithms from NGS (illumina) sequence data. These algorithms were built up as individual programs and opened to the public via paper or our HP.
And we also performed analysis of the distribution of protein localization, denovo assembling of genomes, and SNPs or structural variation detection against S.cerevisiae, S.pombe, Human. Mouse and some bacterias with other many researchers.

Free Research Field

ゲノム情報