Products Report

抗がん剤開発を指向した新規ＰＫＣリガンドの創製と作用機構解析

Planned Research

Project Area	Chemical Biology using bioactive natural products as specific ligands: identification of molecular targets and regulation of bioactivity
Project/Area Number	23102011
Research Category	Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Allocation Type	Single-year Grants
Review Section	Science and Engineering
Research Institution	Kyoto University
Principal Investigator	IRIE Kazuhiro 京都大学, (連合)農学研究科(研究院), 教授 (00168535)
Co-Investigator(Kenkyū-buntansha)	YANAGITA Ryo C. 香川大学, 農学部, 助教 (10598121)
Project Period (FY)	2011-04-01 – 2016-03-31

Research Products
(2 results)

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Patent(Industrial Property Rights) (1 results)

[Journal Article] Binding mode prediction of aplysiatoxin, a potent agonist of protein kinase C, through moleculer simulation and structure-activity study on simplified analogs of the receptor-recognition domain2016
- Author(s)
  Y Ashida, R. C. Yanagita*, C Takahashi, Y Kawanami, K Irie
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 24 Pages: 4218-4227
- DOI
  10.1016/j.bmc.2016.07.011
- Peer Reviewed
[Patent(Industrial Property Rights)] 新規アプリシアトキシン誘導体及びそれを含有する抗がん剤2013
- Inventor(s)
  入江一浩, 菊森将之, 蒲池弘明, 柳田亮, 中川優
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  第6170908号
- Filing Date
  2013-04-16
- Acquisition Date
  2017-07-07