Planned Research
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Our most important achievement is to show that a stereoisomer of natural products is most useful for tuning the target selectivity. Usually, natural product have plural target and functions as a multi-biofunctional molecule. natural product behave like a bunch of keys, not a canonical lock-and-key. We can reduce the side reactions in the body by using a stereoisomer of natural products. We demonstrated the successful example of target tuning of natural products in plant hormone mimicking natural product, coronatine.
天然物有機化学