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2016 Fiscal Year Final Research Report

Development of Chiral Bronsted Acid Catalyst

Planned Research

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Project AreaAdvanced Molecular Transformations by Organocatalysts
Project/Area Number 23105003
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionGakushuin University

Principal Investigator

AKIYAMA TAKAHIKO  学習院大学, 理学部, 教授 (60202553)

Project Period (FY) 2011-04-01 – 2016-03-31
Keywords有機分子触媒 / 選択的合成 / 不斉合成 / 触媒反応 / 光学分割
Outline of Final Research Achievements

Because enantiomers may exhibit different biological activities, development of novel chiral catalyst and efficient asymmetric reactions for the preparation of optically active compounds is an important topic of research interest. We already reported that chiral phosphoric acid derived from (R)-BINOL exhibited efficient catalytic activity as a chiral Bronsted acid. We tried to extend the utility of the chiral phosphoric acid and found several interesting asymmetric reactions.

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Free Research Field

有機合成化学

URL: 

Published: 2018-03-22  

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