Planned Research
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
We have carried out enzymatic and model systems that involve transition metals at the active centers using theoretical calculations. On the basis of large-scale calculations, we considered environmental effects and perturbational effects at the active centers of enzymes. In this study we did collaborative studies with experimental groups about metalloenzymes and model complexes. We demonstrated a spin-state change and electron transfer in proteins are main factors that determine metal-based enzymatic reactions.
化学
