2016 Fiscal Year Final Research Report
Structure and Function of magnetotactic motility machinery
| Project Area | Harmonized supramolecular machinery for motility and its diversity |
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| Project/Area Number |
24117007
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
TAOKA Azuma 金沢大学, 理工研究域自然システム学系, 准教授 (20401888)
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| Project Period (FY) |
2012-06-28 – 2017-03-31
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| Keywords | 磁性細菌 / 細胞骨格 / オルガネラ / アクチン / べん毛 / マグネトソーム / 地磁気 |
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| Outline of Final Research Achievements |
Magnetotactic bacteria synthesize a nano-sized magnetic organelle termed the magnetosome, which they use to assist with their magnetic navigation in a specific bacterial motility called magnetotaxis. Magnetotactic bacteria are ubiquitous in aquatic environments in the world. However, the detailed molecular mechanisms of magneto-reception and magnetotaxis are still an enigma. Here, we focused on the function of MamK cytoskeleton, and analyzed molecular mechanisms of magnetotactic motility through the newly developed method for magnetotaxis quantification and the cutting-edge microscopic techniques, TIRF and high-speed AFM, for imaging dynamics of magnetosome and flagellum in living cells.
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| Free Research Field |
生化学
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