Controle of self-assembly in artificial systems based on precise design of moleular surfaces

2017 Fiscal Year Final Research Report

• Project Area: Dynamical ordering of biomolecular systems for creation of integrated functions
• Project/Area Number: 25102005
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: The University of Tokyo
• Principal Investigator: Hiraoka Shuichi 東京大学, 大学院総合文化研究科, 教授 (10322538)
• Project Period (FY): 2013-06-28 – 2018-03-31
• Keywords: 分子自己集合 / van der Waals力 / 疎水効果 / 分子認識 / 超分子化学 / 自己組織化

Outline of Final Research Achievements

We carried out two unresolved issues in molecular self-assembly: (1) establishing design principle of “molecular hozo” for the construction of discrete self-assemblies only using very weak, non-directional intermolecular interactions (van der Waals and cation-pai interactions) and the hydrophobic effect in water and (2) revealing molecular self-assembly process by a novel method (QASAP), which was developed by us. In the first project, we designed gear-shaped amphiphiles, developed a novel method to synthesize C2v symmetric hexaphenylbenzene derivatives, and succeeded in developing a cubic assembly “nanocube” that is stable at 130 °C in water. In the second project, self-assembly processes of 14 coordination assemblies were revealed by QASAP, which shows several features in molecular self-assembly. Besides, chiral self-sorting processes where enantiomers are spontaneously sorted into homochiral assemblies were revealed by QASAP.

Free Research Field

超分子化学