Study of Complex Molecular Systems by Ultrafast and Nonlinear Spectroscopy

2017 Fiscal Year Final Research Report

• Project Area: Science on Function of Soft Molecular Systems by Cooperation of Theory and Experiment
• Project/Area Number: 25104005
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: TAHARA Tahei 国立研究開発法人理化学研究所, 田原分子分光研究室, 主任研究員 (60217164)
• Co-Investigator(Kenkyū-buntansha): 竹内 佐年 国立研究開発法人理化学研究所, 田原分子分光研究室, 専任研究員 (50280582) ; 石井 邦彦 国立研究開発法人理化学研究所, 田原分子分光研究室, 専任研究員 (80391853) ; 山口 祥一 埼玉大学, 理工学研究科, 教授 (60250239) ; 須藤 雄気 岡山大学, 医歯薬学総合研究科, 教授 (10452202)
• Co-Investigator(Renkei-kenkyūsha): NIHONYANAGI Satoshi 国立研究開発法人理化学研究所, 田原分子分光研究室, 専任研究員 (30443972) ; KURAMOCHI Hikaru 国立研究開発法人理化学研究所, 光量子工学研究領域, 研究員 (40709367)
• Project Period (FY): 2013-06-28 – 2018-03-31
• Keywords: 複雑分子系 / 先端分光計測 / 超高速ダイナミクス / 界面 / 生体分子

Outline of Final Research Achievements

We studied complex molecular systems by the best spectroscopic measurements. We made numerous research achievements, while strongly promoting collaboration with researchers in this project. Particularly, (1) in ultrafast spectroscopy, we have realized an “ultimate” form of time-resolved impulsive stimulated Raman spectroscopy that we developed. We also clarified the ultrafast process of various biomolecules, supramolecules and functional molecules. (2) In interface-selective nonlinear spectroscopy, we have investigated interfacial water structure by utilizing heterodyne-detected vibrational sum-frequency generation spectroscopy (HD-VSFG)developed by us．We also studied interfacial dynamics by developing two-dimensional HD-VSFG spectroscopy and time-resolved measurement with ultraviolet excitation. (3) In the study of single molecule spectroscopy, we developed 2D fluorescence lifetime correlation spectroscopy, We studied protein folding processes, and obtained new important findings.

Free Research Field

物理化学