2017 Fiscal Year Final Research Report
Memory dynamism elucidated by studying on the mechanisms of forgetting in C. elegans
| Project Area | Principles of memory dynamism elucidated from a diversity of learning systems |
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| Project/Area Number |
25115009
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
TERAMOTO Takayuki 九州大学, 理学研究院, 准教授 (90571836)
FUJIWARA Manabi 九州大学, 理学研究院, 助教 (70359933)
SAWATARI Etsuko 九州大学, 基幹教育院, 助教 (60456605)
KUGE Sayuri 九州大学, 理学研究院, 学術研究員 (50260104)
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| Research Collaborator |
ARAI Miari 九州大学, 理学研究院, 学術研究員
KITAZONO Tomohiro 九州大学, 理学研究院, 学術研究員
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| Project Period (FY) |
2013-06-28 – 2018-03-31
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| Keywords | 記憶 / 忘却 / 線虫 / カルシウムイメージング / 行動遺伝学 |
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| Outline of Final Research Achievements |
Animals make memories depending on the sensory information and their environments, although most such memories are forgotten within a few hours as short term memories. We study on the molecular and neuronal mechanisms of active forgetting by using the olfactory learning in C. elegans as a model. In this study, we found that the signaling pathway that are conserved from nematodes to vertabrates properly regulates active forgetting of olfactory learning in the olfactory neurons and their downstream interneurons.
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| Free Research Field |
分子遺伝学
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