Isomer separation of polychlorinated aromatic compounds

1989 Fiscal Year Final Research Report Summary

• Project/Area Number: 01044081
• Research Category: Grant-in-Aid for international Scientific Research
• Allocation Type: Single-year Grants
• Section: Joint Research
• Research Institution: Kyoto Institute of Technology
• Principal Investigator: TANAKA Nobuo Kyoto Institute of Technology, Faculty of Textile Science, 繊維学部, 助教授 (60127165)
• Co-Investigator(Kenkyū-buntansha): HAGLUND P. National Environmental Protection Board, Sweden, 研究員 ; BARNHART E. R. Centers for Disease Control, U. S. A., 防疫センター, 研究員 ; PATTERSON D. G. Centers for Disease Control, U. S. A., 防疫センター, 主任研究員 ; HOSOYA Ken Kyoto Institute of Technology, Faculty of Textile Science, 繊維学部, 助手 (00209248) ; TERABE Shigeru Kyoto University, Faculty of Engineering, 工学部, 助教授 (50115888)
• Project Period (FY): 1989
• Keywords: Reversed-Phase Liquid Chromatography / Electrokinetic Chromatography / Dibenzothiophene / Electrophoresis / Polychlorinated Aromatic Compound / PCB / Dioxin

Research Abstract

Chromatographic separation of polychlorinated aromatic hydrocarbons including polychlorobiphenyls (PCBs), polychlorodibenzo-p-dioxins, and polychlorodibenzothiophenes were examined by using reversed-phase liquid chromatography and electrokinetic chromatography. The newly synthesized aromatic stationary phases such as 2-(1-pyrenyl)ethylsilylated silica gel and nitrated phenylethyl silica gel for reversed-phase liquid chromatography enabled preparative separation of all the 22 isomers of tetrachlorodibenzo-p-dioxin.
Electrokinetic chromatography utilizing a fused silica capillary tubing containing an electrolyte solution afforded separation of isomers of PCBs and dioxins in the presence of water-soluble carriers such as cyclodextrins. The research program showed the usefulness of these new chromatographic methods for the separation of polychlorinated aromatic compounds of environmental concern.

Research Products

• [Publications] N.Tanaka: "Selectivity of 2ー(1ーpyrenyl)ethylsilylated silica gel in the isomer separation of cyclohexane derivatives." J.Chromatographic Science,. 27. 735-740 (1989)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] K.Kimata: "A newly developed stationary phase,nitrated phenylethyl silica gel,and HPLC separation of 1,2,4,6ー/1,2,4,9ーTCDD isomer pair" J.High Resolution Chromatography. 13. 137-138 (1990)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] P.Haglund: "Isolation of toxic polychlorinated biphenyls by electron donor acceptor high performance liquid chromatography using a 2ー(1ーpyrenyl)ethylsilylated silica column." J.Chromatography.
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] S.Terabe: "Separation of highly hydrophobic compounds by cyclodextrin modified micellar electrokinetic chromatography." J.Chromatography.
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] 田中信男: "液体クロマトグラフィ-による芳香族塩素化合物異性体の分離" 環境.
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] E.R.Barnhart: "HPLC elution order of positional isomers of hexachloro-biphenyl with octadecyl-,pyrenylethyl-,and naphthylethyl silylated silica gel as stationary phase" J.Chromatography.
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] N. Tanaka, K. Hosoya, Y. Tachibana, M. Araki, K. Tanaka, A. Kaji,: "Selectivity of 2-(1-pyrenyl)ethylsilylated silica gel in the isomer separation of cyclohexane derivatives." J. Chromatogr. Sci.,. 27. 735-740 (1989)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] K. Kimata, K. Hosoya, N. Tanaka, T. Araki, E. Barnhart, D. G. Patterson, S. Terabe,: "A newly developed stationary phase, nitrated phenylethyl silica gel, and HPLC separation of 1,2,4,6-/1,2,4,9-TCDD isomer pair" J. High Resolut. Chromatogr.13. 137-138 (1990)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] P. Haglund, L. Asplund, U. Jernnas, B. Jansson,: "Isolation of toxic polychlorinated biphenyls by electron donor acceptor high performance liquid chromatography using a 2-(1-pyrenyl)ethylsilylated silica column." J. Chromatogr.
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] S. Terabe, Y. Miyashita, O. Shibata, E. R. Barnhart, L. R. Alexander, D. G. Patterson, B. L. Karger, K. Hosoya, N. Tanaka,: "Separation of highly hydrophobic compounds by cyclodextrin modified micellar electrokinetic chromatography." J. Chromatogr.
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] N. Tanaka: "Isomer separation of polychlorinated aromatic compounds by liquid chromatography (Japanese)" Kankyou(Environment).
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] E. R. Barnhart, N. Tanaka, K. Kimata, K. Hosoya, S. Terabe, L. R. Alexander, D. G. Patterson, Jr.: "HPLC elution order of positional isomers of hexachlorobiphenyl with octadecyl-, pyrenylethyl-, and naphthylethylsilylated silica gel as stationary phase" J. Chromatogr.
  • Description: 「研究成果報告書概要(欧文)」より