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1989 Fiscal Year Final Research Report Summary

Exchange of the informations in the cooperative immunology research between the US-Japan Bords.

Research Project

Project/Area Number 01044088
Research Category

Grant-in-Aid for Overseas Scientific Survey.

Allocation TypeSingle-year Grants
Research InstitutionInstitute for Molecular and Cellular Biology, Osaka University

Principal Investigator

KISHIMOTO Tadamitsu  Institute for Molecular and Cellular Biology, Osaka University, 細胞工学センター, 教授 (10093402)

Co-Investigator(Kenkyū-buntansha) SAKAGUCHI Nobuo  Saga Medical School, 助教授 (70192086)
TAKEMORI Toshitada  National Institute of Health, 細胞免疫部, 部長 (60114295)
TAKATSU Kiyoshi  Kumamoto University Medical School, 医学部, 教授 (10107055)
OKUMURA Ko  Juntendo University, School of Medicine, 医学部, 教授 (50009700)
SASAZUKI Takehiko  Medical Institute of Bioregulation, Kyushu University, 生体防御医学研究所, 教授 (50014121)
Project Period (FY) 1989
KeywordsThe US-Japan Immunology Symposium / Major histocompatibility complex (MHC) / T cell receptor / IgM receptor / Recombinase / Interleukin / IL-5 / IL-6 / NF-IL-6 / Acute phase reaction
Research Abstract

The US-Japan Immunology Symposium sponsered by the US-Japan Medical Cooperative Program was held in January 1990 in New Orleans. The representative immunologists from bothe US and Japan participated in this Symposium and discussed about the up-to-date results on the regulation of the immune system.
The topics were as follows; 1) The interaction between the major histocompatibility antigens and antigenic peptide fragments. 2) The molecules associated with IgM receptor on B cells. 3) The molecules involved in the recombination of the immunoglobulin genes and T cell receptor genes. 4) Interleukines and their receptors, especially the nuclear factor involved in the expression of IL-6.

  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] Kishimoto,T.: "The Biology of interleukin 6." Blood. 74. 1-10 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Taga,T.,T.Kishimoto,et al.: "Interleukin-6 triggers the association of its receptor with a possible signal transducer,gp130." Cell. 58. 573-581 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Suematsu,S.,T.Kishimoto,et al.: "IgG_1 plasmacytosis in interleukin 6 transgenic mice." Proc.Natl.Acad.Sci.,USA. 86. 7547-7551 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yagaita,H.,K.Okumura,et al.: "Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells." Proc.Natl.Acad.Scie.,USA. 87. 645-649 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hitoshi,Y.,K.Takatsu,et al.: "Distribution of interleukin-5 receptor-positive B cells:expression of IL-5-receptor on Ly-1(CD5)-positive B cells." J.Immunol. (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kimoto,T.,T.Takemori,et al.: "B cell precursors are present in the tymus as early development." Eur.J.Immunol.19. 97-104 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sasazuki,T.et al.: "Differential roles of HLA-DR and DQ in immune regulation.in Progress <in>___ー Immunology VII" Springer velag,Berlin, 853-860 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kishimoto,T.and T.Hirano: "B lympocyte activation,proliferation and immunoglobulin secretion.<in>___ー Fundamental immunology,Second Edition" Raven Press,New York, 385-411 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kishimoto, T: "The Biology of interleukin 6." Blood. 74. 1-10 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yagita, H., K. Okumura, et al.: "Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells." Proc. Natl. Acad. Sci., USA. 87. 645-649 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hitoshi, Y., K. Takatsu, et al.: "Distribution of interleukin-5 receptor-positive B cells: Express of IL-5-receptor on Ly-1(CD5)-positive B cells." J. Immunol.in press. (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kimoto, T., T. Takemori, et al.: "B cell precursors are present in the tymus as early development." Eur. J. Immunol.19. 97-104 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sasazuki, T., et al.: Differential role sof HLA-DR and DQ in immune regulation. In Progress in Immunology VII. Springre velag, Berlin, 853-860 (1989)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1993-03-26  

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