1990 Fiscal Year Final Research Report Summary
DNA Rearrangements Caused by Non-Homologous Recombinatin and Gene Expression
| Project/Area Number |
01480540
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
分子遺伝学・分子生理学
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| Research Institution | Science University of Tokyo |
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Principal Investigator |
IIDA Shigeru Sci. Univ. Tokyo, Dept. Biol. Sci. & Tech., Professor, 基礎工学部, 教授 (30012777)
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| Co-Investigator(Kenkyū-buntansha) |
MIYAZAKI Chikara Sci. Univ. Tokyo, Dept. Biol. Sci & Tech., Research Associate,, 基礎工学部, 助手 (40190764)
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| Project Period (FY) |
1989 – 1990
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| Keywords | Genetic Recombination / Non-Homologous Recombination / DNA Rearrangements / Gene Expression / Mobile Genetic Elements / Transposable Elements / Higher Plants / Drug Resistance Marker Genes |
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| Research Abstract |
DNA rearrangements often affect the expression of genes. Site-specific Min DNA inversion found on the plasmid p15B is a good example, which we have characterized. It consists of site-specific recombinase gene min, six crossover sites and an active recombination enhancer. Orientation of the invertible DNA segments determines the expression of sets of particular genes.
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