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1990 Fiscal Year Final Research Report Summary

in vivo Analysis of Dopamine in rat brain using voltammetry with randompulse signal

Research Project

Project/Area Number 01550575
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field 工業分析化学
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

ICHISE Mitsunojo  KYOTO UNIVERSITY.FACULTY OF ENGINEERING.PROFESSOR, 工学部, 教授 (00025917)

Co-Investigator(Kenkyū-buntansha) MORISHITA Fujio  KYOTO UNIVERSITY,FACULTY OF ENGINEERING,ASSISTANT, 工学部, 助手 (30026281)
MIWA Souiti  KYOTO UNIVERSITY,FACULTY OF MEDICINE,INSTRUCTER, 医学部, 講師 (40157706)
Project Period (FY) 1989 – 1990
KeywordsNeurotransmitter / Dopamine / Carbonfiberelectrode / Random pulse / Learning machine / Voltammetry / in vivo Analysis
Research Abstract

For the purpose of analysing neurotransmitter Dopamine and its metabolite separately, a voltammetry using random pulses and learning machine has been developped. By this method, Dopamine dynamics has been measured in the brain of rats injected with PARGYLINE,RECERPINE and AMPHETAMINE.
In all of the cases, the crosschecks with the brain dialysis method give good results.

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Published: 1999-03-16  

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